2q37 copy number variation syndrome (Homo sapiens)

From WikiPathways

Revision as of 15:58, 26 July 2023 by Fehrhart (Talk | contribs)
Jump to: navigation, search
NucleusSensory neuronMYO5A151, 187147, 19710933, 107108148192, 2217723, 1404, 92, 110, 133, 189...26, 74137, 173199131, 21189, 135, 182, 201, 220130170, 2088514249, 52, 160, 1947, 24, 79, 16386, 12850, 99, 1042, 48, 90, 93, 106...4, 92, 110, 161, 18994, 111, 117, 193, 21573, 2229, 204, 2281693, 14, 22, 29, 39...88, 2051361643043, 62, 17437, 42, 112, 1161534111311, 72836, 75, 9664, 165, 1814721631, 91, 195, 22387, 13245, 124, 143, 157, 178Axons/Dendrites180, 190, 21344, 4617134, 158, 22412, 34, 139, 144, 145, 149...179, 2006395, 11967, 76, 207proteins98, 10024, 16338, 80, 101, 218159, 22621925, 35, 19920, 21, 81, 11868, 12716, 19675, 85, 2148, 1525, 58, 167, 184, 203156, 175188183, 20217120, 217113, 55, 12510, 15, 975732, 6127, 36, 103, 18660, 102, 122, 172, 1771627019819, 84, 115ATG8 familyAcetylation ofhistone H4DCVMitochondrionribosomeSynaptic siteExact function unknownchr2:239,716,679230Sensation of coldExact function unknownExact function unknownCold temperatures and cooling agentsDepolarizationChanging environmental conditions Exact function unknownGDPSCF-like ECS E3ligase complexMAP4protein-serine-threonine kinasesCilium AssemblyrRNA modificationin the mitochondrionProteinactin cytoskeleton reorganizationMOZ1 histoneacetyltransferase complexFilament-forming complexsterol metabolic processGDPextracellular matrixOlfactory receptor activityGlycogen synthesis and degradationoxidative stressHBO1-5.1 histoneacetyltransferase complextubulinUDP-glucuronosyl/UDP-glucosyltransferasemitotic spindle assemblyProtein phosphatase 1UBA3-NAE1 E1 complexcysteine proteaseMyogenesisCOP9 signalosome variant 1bone remodelingbleeding NeddylationCircadian Clockaminopeptidase activitySignaling by FGFR2microtubuleProtein-tyrosine-phosphataseactinMitochondrial respiratory chain complex IerythroblastElectron transport chain:OXPHOS system in mitochondriaProtein ubiquitinationCell junction organizationhistone deacetylase activityPIP3intercellular bridgeMAPK cascadepositive regulation of smooth muscle cell proliferationProlactin receptorsignalingprotein ubiquitinationAmino acids regulate mTORC1Endothelin pathwaysCOP9 signalosomevesicle transportalong microtubuleTransferrin receptormelanosomecollagen VINeural crest differentiationmelanosome transportCENP-A nucleosome complexEstrogen metabolismclathrin-dependent endocytosisGABARAPCFLARGMEB1dTMPCancer immunotherapy by PD-1 blockadeGABARAPL1CALM1GABARAPL2dTDPAGAP1-IT1MAP1LC3CSNED1MAP1LC3AABCA1MAP1LC3BMYEOV2peroxynitriteOR5S1PnitrateMEF2C(R)-2-hydroxyglutaratePDCD1NFKBIA2-oxoglutarateNEDD8MLPHOR9S24PUGT1A10HSPE1P9SPP2USP40MIR4786RN7SL204PTNFSH3BP4ARF1UGT1A13PCXCR4ANKMY1DUSP28ACKR3SH3BP4UBE2FPhosphatidic acidRNU1-31PFAM132BRAB17SEPTIN2PDX1EEF1A1RAMP1ATG4BDNAJB3RAB27ARAMP1ASB18MEF2APRR21HAMPRNU6-1051PHDAC4DTYMKTRPM8IL13RA1ARL4CRBM44UGT1A5NDUFA10RRAGCOTOSSTK25EGFRGPC1D2HGDHUGT1A2PAGAP1OR6B3SEPTIN12GBX2RNU6-1333PPRLMIR4269CAPN10-AS1C2orf54KLHL30HDLBPILKAPUGT1A6TRAF3IP1TMSB10P1COL6A3RNU7-127PCAPN10MIR4440PER2UBE2F-SCLYH2Oacceptor beta-D-glucuronosideUGT1A11PRAC1UGT1A8HES1heparan sulfate groupRRAGDRPL17P11CALCAGPR35OR6B2phosphatidylserineAQP12ABOKkynurenic acidCXCL12IQCA1JUNRRAGBGPC1MLPHLRRFIP1Ca2+LINC01107CYTH1HES6PASKRNU6-234PMIR2467RNA5SP122ANO7TRAF3CXXC11NEU4TRPM8glucuronate acceptorL-selenocysteineMYOD1ING5FARP2CALCRLRNPEPL1MIR149L-alanineMTERFD2MSL3P1CENPAITGB3DGKD1,2-diacyl-sn-glycerolsAGXTTHAP4ARF5CXCL11SEPTIN6GAL3ST2cholesterolCa2+MIR4441MYOGUGT1A1SEPTIN4L-alanineMIR3133TP53HJURPSCLYCOPS8DISC1UGT1A7ESPNLITPK1MROH2AUGT1A3PDGFATWIST2UGT1A12PRNU6-1140PBOK-AS1RPL3P5PRLHCICP10KIF1AAQP12AUGT1A9RPS6IRF8Na+PPP1R7pyruvateUGT1A4IL1BAQP12BILKSEPT2GYS1ASCL1ANO7ASB1RRAGACa2+Na+ARL4CCYTH2CYTH4CYTH357, 166575740, 82ARF5ARF117966, 154, 212154, 212NFKBIAIRF8TP53JUNITPK138, 80, 101, 21838, 80, 101, 21813444, 4644, 4644, 4644, 46Exact function unknownAQP12BH2O19, 115Exact function unknownRPS6EEF1A1GYS1PDX15912128galactosylceramidephosphatidylcholinephosphatidylserinegalactosylceramidephosphatidylcholine43, 62, 17443, 62, 174RAC1Acetylation ofhistone H3188553, 54, 19124, 78, 105, 163Metapathway biotransformationPhase I and IIExact function unknowncholesterolTransferrin receptorPIP2Factors and pathways affectinginsulin-like growth factor(IGF1)-Akt signalingInterleukin-4 andInterleukin-13 signalingOlfactory receptor activitysensory perception of sound Ca2+Integrin-mediated cell adhesionDegradation of the extracellular matrixG proteinsignaling pathwaysDCVSemaphorin interactionsIntegrin signalingApoptosisMacroautophagyCitric acid cycle andrespiratory electron transport MetapathwaybiotransformationPhase I and IISialic acid metabolismLegendTranslocationGene ProductMetaboliteRNA geneMIM-stimulation of an enzyme or a gene leading to its activation or expressionData node for a micro RNA or another RNA geneData node for a pathwayMIM-inhibition of a compound's function or a processMIM-catalysis of a compound by an enzymePathwayMIM-transcription-translation of a geneData node for a metaboliteDashed line indicates unclear mechanismof interaction/unclear intermediatesData node for a gene or its productMIM-conversion of a compound to anotherMIM-binding of a compound to anotherData node for a pseudo genePseudogeneproteinsPhosphorylated proteinComplexchr2:234,275,216chr2:243,199,373187151, 230SCF-like ECS E3 ligase complex89, 135, 182, 201, 22053, 54, 19153, 54, 19153, 54, 19153, 54, 19153, 54, 19153, 54, 19153, 54, 191GTP53, 54, 191GTPGDPGTP5, 58, 167, 184, 203NEUROPATHOLOGYData node for associated neuropathologyD-2-HYDROXYGLUTARIC ACIDURIA 1; D2HGA1SPASTIC PARAPLEGIA 30, AUTOSOMAL DOMINANT; SPG30Alzheimer diseaseMITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 22; MC1DN22


Description

The 2q37 copy number variation syndrome can result in the loss of up to 78 protein-coding genes. Patients with 2q37 CNV syndrome had intellectual disability, facial dysmorphism and skeletal and digit malformations (DOI: 10.1186/1755-8794-7-19,DOI: 10.1016/j.gene.2013.06.056). Research linked changes in HDAC4 gene with obesity of 2q37 patients (DOI: 10.1016/j.gene.2013.06.056). The chromosomal locations are from Kirov et al. 2014 (literature cited there) (chr2:239,716,679-243,199,373) and the larger one from Sakai et al. 2014 (chr2:234,275,216-243,199,373).

Try the New WikiPathways

View approved pathways at the new wikipathways.org.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Itoh T, Rai T, Kuwahara M, Ko SB, Uchida S, Sasaki S, Ishibashi K; ''Identification of a novel aquaporin, AQP12, expressed in pancreatic acinar cells.''; Biochem Biophys Res Commun, 2005 PubMed Europe PMC Scholia
  2. Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT; ''Accessory subunits are integral for assembly and function of human mitochondrialcomplex I.''; Nature, 2016 PubMed Europe PMC Scholia
  3. Watanabe N, Araki W, Chui DH, Makifuchi T, Ihara Y, Tabira T; ''Glypican-1 as an Abeta binding HSPG in the human brain: its localization in DIG domains and possible roles in the pathogenesis of Alzheimer's disease.''; FASEB J, 2004 PubMed Europe PMC Scholia
  4. Horita S, Nomura Y, Sato Y, Shimamura T, Iwata S, Nomura N; ''High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1.''; Sci Rep, 2016 PubMed Europe PMC Scholia
  5. Cámara Y, Asin-Cayuela J, Park CB, Metodiev MD, Shi Y, Ruzzenente B, Kukat C, Habermann B, Wibom R, Hultenby K, Franz T, Erdjument-Bromage H, Tempst P, Hallberg BM, Gustafsson CM, Larsson NG; ''MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome.''; Cell Metab, 2011 PubMed Europe PMC Scholia
  6. Khachigian LM, Santiago FS, Rafty LA, Chan OL, Delbridge GJ, Bobik A, Collins T, Johnson AC; ''GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury.''; Circ Res, 1999 PubMed Europe PMC Scholia
  7. Tian H, Li CS, Zhao KW, Wang JC, Duarte ME, David CL, Phan K, Atti E, Brochmann EJ, Murray SS; ''A carboxy terminal BMP/TGF-β binding site in secreted phosphoprotein 24 kD independently affects BMP-2 activity.''; J Cell Biochem, 2015 PubMed Europe PMC Scholia
  8. Ceulemans H, Vulsteke V, De Maeyer M, Tatchell K, Stalmans W, Bollen M; ''Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  9. Yang J, Zhu H, Zhang T, Ding J; ''Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations.''; Cell Discov, 2021 PubMed Europe PMC Scholia
  10. Helaakoski T, Vuori K, Myllylä R, Kivirikko KI, Pihlajaniemi T; ''Molecular cloning of the alpha-subunit of human prolyl 4-hydroxylase: the complete cDNA-derived amino acid sequence and evidence for alternative splicing of RNA transcripts.''; Proc Natl Acad Sci U S A, 1989 PubMed Europe PMC Scholia
  11. Jo YK, Park NY, Park SJ, Kim BG, Shin JH, Jo DS, Bae DJ, Suh YA, Chang JH, Lee EK, Kim SY, Kim JC, Cho DH; ''O-GlcNAcylation of ATG4B positively regulates autophagy by increasing its hydroxylase activity.''; Oncotarget, 2016 PubMed Europe PMC Scholia
  12. Harzenetter MD, Keller U, Beer S, Riedl C, Peschel C, Holzmann B; ''Regulation and function of the CGRP receptor complex in human granulopoiesis.''; Exp Hematol, 2002 PubMed Europe PMC Scholia
  13. Tosoni D, Puri C, Confalonieri S, Salcini AE, De Camilli P, Tacchetti C, Di Fiore PP; ''TTP specifically regulates the internalization of the transferrin receptor.''; Cell, 2005 PubMed Europe PMC Scholia
  14. Nagashima K, Torii S, Yi Z, Igarashi M, Okamoto K, Takeuchi T, Izumi T; ''Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.''; FEBS Lett, 2002 PubMed Europe PMC Scholia
  15. Kuwasako K, Cao YN, Nagoshi Y, Tsuruda T, Kitamura K, Eto T; ''Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins.''; Mol Pharmacol, 2004 PubMed Europe PMC Scholia
  16. Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD; ''Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.''; Am J Hum Genet, 2009 PubMed Europe PMC Scholia
  17. Monda JK, Scott DC, Miller DJ, Lydeard J, King D, Harper JW, Bennett EJ, Schulman BA; ''Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.''; Structure, 2013 PubMed Europe PMC Scholia
  18. Sneitz N, Vahermo M, Mosorin J, Laakkonen L, Poirier D, Finel M; ''Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.''; Drug Metab Dispos, 2013 PubMed Europe PMC Scholia
  19. Brochmann EJ, Behnam K, Murray SS; ''Bone morphogenetic protein-2 activity is regulated by secreted phosphoprotein-24 kd, an extracellular pseudoreceptor, the gene for which maps to a region of the human genome important for bone quality.''; Metabolism, 2009 PubMed Europe PMC Scholia
  20. Lo KY, Kuzmin A, Unger SM, Petersen JD, Silverman MA; ''KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons.''; Neurosci Lett, 2011 PubMed Europe PMC Scholia
  21. Jovancevic N, Wunderlich KA, Haering C, Flegel C, Maßberg D, Weinrich M, Weber L, Tebbe L, Kampik A, Gisselmann G, Wolfrum U, Hatt H, Gelis L; ''Deep Sequencing of the Human Retinae Reveals the Expression of Odorant Receptors.''; Front Cell Neurosci, 2017 PubMed Europe PMC Scholia
  22. Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ; ''Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7.''; Proc Natl Acad Sci U S A, 2010 PubMed Europe PMC Scholia
  23. Williams EL, Acquaviva C, Amoroso A, Chevalier F, Coulter-Mackie M, Monico CG, Giachino D, Owen T, Robbiano A, Salido E, Waterham H, Rumsby G; ''Primary hyperoxaluria type 1: update and additional mutation analysis of the AGXT gene.''; Hum Mutat, 2009 PubMed Europe PMC Scholia
  24. Zheng J, Yang X, Harrell JM, Ryzhikov S, Shim EH, Lykke-Andersen K, Wei N, Sun H, Kobayashi R, Zhang H; ''CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex.''; Mol Cell, 2002 PubMed Europe PMC Scholia
  25. Skytte Rasmussen M, Mouilleron S, Kumar Shrestha B, Wirth M, Lee R, Bowitz Larsen K, Abudu Princely Y, O'Reilly N, Sjøttem E, Tooze SA, Lamark T, Johansen T; ''ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.''; Autophagy, 2017 PubMed Europe PMC Scholia
  26. Duran C, Qu Z, Osunkoya AO, Cui Y, Hartzell HC; ''ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.''; Am J Physiol Cell Physiol, 2012 PubMed Europe PMC Scholia
  27. Uhle S, Medalia O, Waldron R, Dumdey R, Henklein P, Bech-Otschir D, Huang X, Berse M, Sperling J, Schade R, Dubiel W; ''Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome.''; EMBO J, 2003 PubMed Europe PMC Scholia
  28. Yagita K, Tamanini F, Yasuda M, Hoeijmakers JH, van der Horst GT, Okamura H; ''Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.''; EMBO J, 2002 PubMed Europe PMC Scholia
  29. Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC; ''Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4).''; Autophagy, 2010 PubMed Europe PMC Scholia
  30. Bizet AA, Becker-Heck A, Ryan R, Weber K, Filhol E, Krug P, Halbritter J, Delous M, Lasbennes MC, Linghu B, Oakeley EJ, Zarhrate M, Nitschké P, Garfa-Traore M, Serluca F, Yang F, Bouwmeester T, Pinson L, Cassuto E, Dubot P, Elshakhs NAS, Sahel JA, Salomon R, Drummond IA, Gubler MC, Antignac C, Chibout S, Szustakowski JD, Hildebrandt F, Lorentzen E, Sailer AW, Benmerah A, Saint-Mezard P, Saunier S; ''Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization.''; Nat Commun, 2015 PubMed Europe PMC Scholia
  31. Stenmark H; ''Rab GTPases as coordinators of vesicle traffic.''; Nat Rev Mol Cell Biol, 2009 PubMed Europe PMC Scholia
  32. Voets T, Droogmans G, Wissenbach U, Janssens A, Flockerzi V, Nilius B; ''The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.''; Nature, 2004 PubMed Europe PMC Scholia
  33. Eide EJ, Woolf MF, Kang H, Woolf P, Hurst W, Camacho F, Vielhaber EL, Giovanni A, Virshup DM; ''Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.''; Mol Cell Biol, 2005 PubMed Europe PMC Scholia
  34. Kirov G, Rees E, Walters JT, Escott-Price V, Georgieva L, Richards AL, Chambert KD, Davies G, Legge SE, Moran JL, McCarroll SA, O'Donovan MC, Owen MJ; ''The penetrance of copy number variations for schizophrenia and developmental delay.''; Biol Psychiatry, 2014 PubMed Europe PMC Scholia
  35. Kalkat M, Garcia J, Ebrahimi J, Melland-Smith M, Todros T, Post M, Caniggia I; ''Placental autophagy regulation by the BOK-MCL1 rheostat.''; Autophagy, 2013 PubMed Europe PMC Scholia
  36. Robert C, Long GV, Brady B, Dutriaux C, Maio M, Mortier L, Hassel JC, Rutkowski P, McNeil C, Kalinka-Warzocha E, Savage KJ, Hernberg MM, Lebbé C, Charles J, Mihalcioiu C, Chiarion-Sileni V, Mauch C, Cognetti F, Arance A, Schmidt H, Schadendorf D, Gogas H, Lundgren-Eriksson L, Horak C, Sharkey B, Waxman IM, Atkinson V, Ascierto PA; ''Nivolumab in previously untreated melanoma without BRAF mutation.''; N Engl J Med, 2015 PubMed Europe PMC Scholia
  37. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM; ''RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor.''; Nature, 1998 PubMed Europe PMC Scholia
  38. Pengo N, Prak K, Costa JR, Luft C, Agrotis A, Freeman J, Gewinner CA, Chan AWE, Selwood DL, Kriston-Vizi J, Ketteler R; ''Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells.''; Front Cell Dev Biol, 2018 PubMed Europe PMC Scholia
  39. Ylikallio E, Kim D, Isohanni P, Auranen M, Kim E, Lönnqvist T, Tyynismaa H; ''Dominant transmission of de novo KIF1A motor domain variant underlying pure spastic paraplegia.''; Eur J Hum Genet, 2015 PubMed Europe PMC Scholia
  40. Greenbaum MP, Iwamori T, Buchold GM, Matzuk MM; ''Germ cell intercellular bridges.''; Cold Spring Harb Perspect Biol, 2011 PubMed Europe PMC Scholia
  41. Thompson MW, Beasley KA, Schmidt MD, Seipelt RL; ''Arginyl aminopeptidase-like 1 (RNPEPL1) is an alternatively processed aminopeptidase with specificity for methionine, glutamine, and citrulline residues.''; Protein Pept Lett, 2009 PubMed Europe PMC Scholia
  42. Kohroki J, Nishiyama T, Nakamura T, Masuho Y; ''ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.''; FEBS Lett, 2005 PubMed Europe PMC Scholia
  43. Huang T, Kim CK, Alvarez AA, Pangeni RP, Wan X, Song X, Shi T, Yang Y, Sastry N, Horbinski CM, Lu S, Stupp R, Kessler JA, Nishikawa R, Nakano I, Sulman EP, Lu X, James CD, Yin XM, Hu B, Cheng SY; ''MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma.''; Cancer Cell, 2017 PubMed Europe PMC Scholia
  44. Durgan J, Lystad AH, Sloan K, Carlsson SR, Wilson MI, Marcassa E, Ulferts R, Webster J, Lopez-Clavijo AF, Wakelam MJ, Beale R, Simonsen A, Oxley D, Florey O; ''Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine.''; Mol Cell, 2021 PubMed Europe PMC Scholia
  45. Tiainen P, Pasanen A, Sormunen R, Myllyharju J; ''Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV.''; J Biol Chem, 2008 PubMed Europe PMC Scholia
  46. Shiozaki K, Yamaguchi K, Takahashi K, Moriya S, Miyagi T; ''Regulation of sialyl Lewis antigen expression in colon cancer cells by sialidase NEU4.''; J Biol Chem, 2011 PubMed Europe PMC Scholia
  47. Pla P, Monsoro-Burq AH; ''The neural border: Induction, specification and maturation of the territory that generates neural crest cells.''; Dev Biol, 2018 PubMed Europe PMC Scholia
  48. Doyon Y, Cayrou C, Ullah M, Landry AJ, Côté V, Selleck W, Lane WS, Tan S, Yang XJ, Côté J; ''ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.''; Mol Cell, 2006 PubMed Europe PMC Scholia
  49. Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z; ''Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.''; EMBO J, 2007 PubMed Europe PMC Scholia
  50. Thebault S, Lemonnier L, Bidaux G, Flourakis M, Bavencoffe A, Gordienko D, Roudbaraki M, Delcourt P, Panchin Y, Shuba Y, Skryma R, Prevarskaya N; ''Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
  51. Ishibashi K, Tanaka Y, Morishita Y; ''The role of mammalian superaquaporins inside the cell: An update.''; Biochim Biophys Acta Biomembr, 2021 PubMed Europe PMC Scholia
  52. Sato M, Liu K, Sasaki S, Kunii N, Sakai H, Mizuno H, Saga H, Sakane F; ''Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 amongdiacylglycerol kinase isozymes using a new non-radioactive assay method.''; Pharmacology, 2013 PubMed Europe PMC Scholia
  53. Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, Rot A, Thelen M; ''CXCR7 functions as a scavenger for CXCL12 and CXCL11.''; PLoS One, 2010 PubMed Europe PMC Scholia
  54. Hori T, Osaka F, Chiba T, Miyamoto C, Okabayashi K, Shimbara N, Kato S, Tanaka K; ''Covalent modification of all members of human cullin family proteins by NEDD8.''; Oncogene, 1999 PubMed Europe PMC Scholia
  55. Reed AL, Yamazaki H, Kaufman JD, Rubinstein Y, Murphy B, Johnson AC; ''Molecular cloning and characterization of a transcription regulator with homology to GC-binding factor.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
  56. Haliloglu G, Temucin CM, Oguz KK, Celiker A, Coskun T, Sass JO, Fischer J, Topcu M; ''Peripheral neuropathy in a patient with D-2-hydroxyglutaric aciduria.''; J Inherit Metab Dis, 2009 PubMed Europe PMC Scholia
  57. Eckhardt K, Troger J, Reissmann J, Katschinski DM, Wagner KF, Stengel P, Paasch U, Hunziker P, Borter E, Barth S, Schlafli P, Spielmann P, Stiehl DP, Camenisch G, Wenger RH; ''Male germ cell expression of the PAS domain kinase PASKIN and its novel target eukaryotic translation elongation factor eEF1A1.''; Cell Physiol Biochem, 2007 PubMed Europe PMC Scholia
  58. Yang A, Pantoom S, Wu YW; ''Distinct Mechanisms for Processing Autophagy Protein LC3-PE by RavZ and ATG4B.''; Chembiochem, 2020 PubMed Europe PMC Scholia
  59. Brown AE, Yeaman SJ, Walker M; ''Targeted suppression of calpain-10 expression impairs insulin-stimulated glucose uptake in cultured primary human skeletal muscle cells.''; Mol Genet Metab, 2007 PubMed Europe PMC Scholia
  60. Murray SS, Wang JC, Duarte ME, Zhao KW, Tian H, Francis T, Brochmann Murray EJ; ''The bone matrix protein secreted phosphoprotein 24 kD (Spp24): bone metabolism regulator and starting material for biotherapeutic materials.''; Histol Histopathol, 2015 PubMed Europe PMC Scholia
  61. Kauffman KJ, Yu S, Jin J, Mugo B, Nguyen N, O'Brien A, Nag S, Lystad AH, Melia TJ; ''Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.''; Autophagy, 2018 PubMed Europe PMC Scholia
  62. Xia C, Ma W, Stafford LJ, Liu C, Gong L, Martin JF, Liu M; ''GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.''; Mol Cell Biol, 2003 PubMed Europe PMC Scholia
  63. Rozen S, Füzesi-Levi MG, Ben-Nissan G, Mizrachi L, Gabashvili A, Levin Y, Ben-Dor S, Eisenstein M, Sharon M; ''CSNAP Is a Stoichiometric Subunit of the COP9 Signalosome.''; Cell Rep, 2015 PubMed Europe PMC Scholia
  64. Yakovlev AG, Di Giovanni S, Wang G, Liu W, Stoica B, Faden AI; ''BOK and NOXA are essential mediators of p53-dependent apoptosis.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
  65. Nguyen TN, Padman BS, Zellner S, Khuu G, Uoselis L, Lam WK, Skulsuppaisarn M, Lindblom RSJ, Watts EM, Behrends C, Lazarou M; ''ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system.''; Mol Cell, 2021 PubMed Europe PMC Scholia
  66. Yang Z, Wilkie-Grantham RP, Yanagi T, Shu CW, Matsuzawa S, Reed JC; ''ATG4B (Autophagin-1) phosphorylation modulates autophagy.''; J Biol Chem, 2015 PubMed Europe PMC Scholia
  67. Foltz DR, Jansen LE, Bailey AO, Yates JR 3rd, Bassett EA, Wood S, Black BE, Cleveland DW; ''Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.''; Cell, 2009 PubMed Europe PMC Scholia
  68. Sabnis AS, Shadid M, Yost GS, Reilly CA; ''Human lung epithelial cells express a functional cold-sensing TRPM8 variant.''; Am J Respir Cell Mol Biol, 2008 PubMed Europe PMC Scholia
  69. Vanselow K, Vanselow JT, Westermark PO, Reischl S, Maier B, Korte T, Herrmann A, Herzel H, Schlosser A, Kramer A; ''Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS).''; Genes Dev, 2006 PubMed Europe PMC Scholia
  70. Keesler GA, Camacho F, Guo Y, Virshup D, Mondadori C, Yao Z; ''Phosphorylation and destabilization of human period I clock protein by human casein kinase I epsilon.''; Neuroreport, 2000 PubMed Europe PMC Scholia
  71. Sakai Y, Souzaki R, Yamamoto H, Matsushita Y, Nagata H, Ishizaki Y, Torisu H, Oda Y, Taguchi T, Shaw CA, Hara T; ''Testicular sex cord-stromal tumor in a boy with 2q37 deletion syndrome.''; BMC Med Genomics, 2014 PubMed Europe PMC Scholia
  72. Fitzsimmons TJ, Zhao X, Wank SA; ''The extracellular domain of receptor activity-modifying protein 1 is sufficient for calcitonin receptor-like receptor function.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
  73. Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S; ''Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms.''; Mol Cell Biol, 2003 PubMed Europe PMC Scholia
  74. Hofmann I, Thompson A, Sanderson CM, Munro S; ''The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.''; Curr Biol, 2007 PubMed Europe PMC Scholia
  75. Olt J, Mburu P, Johnson SL, Parker A, Kuhn S, Bowl M, Marcotti W, Brown SD; ''The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells.''; PLoS One, 2014 PubMed Europe PMC Scholia
  76. Wang J, Simonavicius N, Wu X, Swaminath G, Reagan J, Tian H, Ling L; ''Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
  77. Esmaeeli Nieh S, Madou MR, Sirajuddin M, Fregeau B, McKnight D, Lexa K, Strober J, Spaeth C, Hallinan BE, Smaoui N, Pappas JG, Burrow TA, McDonald MT, Latibashvili M, Leshinsky-Silver E, Lev D, Blumkin L, Vale RD, Barkovich AJ, Sherr EH; ''De novo mutations in KIF1A cause progressive encephalopathy and brain atrophy.''; Ann Clin Transl Neurol, 2015 PubMed Europe PMC Scholia
  78. Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F; ''HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion.''; Biochem Biophys Res Commun, 2007 PubMed Europe PMC Scholia
  79. van Blitterswijk WJ, Houssa B; ''Properties and functions of diacylglycerol kinases.''; Cell Signal, 2000 PubMed Europe PMC Scholia
  80. Naba A, Clauser KR, Lamar JM, Carr SA, Hynes RO; ''Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters.''; Elife, 2014 PubMed Europe PMC Scholia
  81. Niu Y, Murata T, Watanabe K, Kawakami K, Yoshimura A, Inoue J, Puri RK, Kobayashi N; ''MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation.''; FEBS Lett, 2003 PubMed Europe PMC Scholia
  82. Stucchi R, Plucińska G, Hummel JJA, Zahavi EE, Guerra San Juan I, Klykov O, Scheltema RA, Altelaar AFM, Hoogenraad CC; ''Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca2+/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites.''; Cell Rep, 2018 PubMed Europe PMC Scholia
  83. Honke K, Tsuda M, Koyota S, Wada Y, Iida-Tanaka N, Ishizuka I, Nakayama J, Taniguchi N; ''Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Gal beta 1-3/1-4GlcNAc-R) oligosaccharides.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
  84. Kubo T, Yamashita T, Yamaguchi A, Sumimoto H, Hosokawa K, Tohyama M; ''A novel FERM domain including guanine nucleotide exchange factor is involved in Rac signaling and regulates neurite remodeling.''; J Neurosci, 2002 PubMed Europe PMC Scholia
  85. Li M, Hou Y, Wang J, Chen X, Shao ZM, Yin XM; ''Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates.''; J Biol Chem, 2011 PubMed Europe PMC Scholia
  86. Spiliotis ET, Hunt SJ, Hu Q, Kinoshita M, Nelson WJ; ''Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules.''; J Cell Biol, 2008 PubMed Europe PMC Scholia
  87. Ray P, Mihalko LA, Coggins NL, Moudgil P, Ehrlich A, Luker KE, Luker GD; ''Carboxy-terminus of CXCR7 regulates receptor localization and function.''; Int J Biochem Cell Biol, 2012 PubMed Europe PMC Scholia
  88. Herrmann L, Dittmar T, Erdmann KS; ''The protein tyrosine phosphatase PTP-BL associates with the midbody and is involved in the regulation of cytokinesis.''; Mol Biol Cell, 2003 PubMed Europe PMC Scholia
  89. da Silva Xavier G, Farhan H, Kim H, Caxaria S, Johnson P, Hughes S, Bugliani M, Marselli L, Marchetti P, Birzele F, Sun G, Scharfmann R, Rutter J, Siniakowicz K, Weir G, Parker H, Reimann F, Gribble FM, Rutter GA; ''Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.''; Diabetologia, 2011 PubMed Europe PMC Scholia
  90. Girard H, Lévesque E, Bellemare J, Journault K, Caillier B, Guillemette C; ''Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity.''; Pharmacogenet Genomics, 2007 PubMed Europe PMC Scholia
  91. Burckhardt CJ, Minna JD, Danuser G; ''SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt.''; Dev Cell, 2021 PubMed Europe PMC Scholia
  92. Hummel JJA, Hoogenraad CC; ''Specific KIF1A-adaptor interactions control selective cargo recognition.''; J Cell Biol, 2021 PubMed Europe PMC Scholia
  93. Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, Weber JS, Joshua AM, Hwu WJ, Gangadhar TC, Patnaik A, Dronca R, Zarour H, Joseph RW, Boasberg P, Chmielowski B, Mateus C, Postow MA, Gergich K, Elassaiss-Schaap J, Li XN, Iannone R, Ebbinghaus SW, Kang SP, Daud A; ''Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial.''; Lancet, 2014 PubMed Europe PMC Scholia
  94. Su G, Meyer K, Nandini CD, Qiao D, Salamat S, Friedl A; ''Glypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cells.''; Am J Pathol, 2006 PubMed Europe PMC Scholia
  95. Sueda R, Kageyama R; ''Regulation of active and quiescent somatic stem cells by Notch signaling.''; Dev Growth Differ, 2020 PubMed Europe PMC Scholia
  96. Garcia-Gonzalo FR, Corbit KC, Sirerol-Piquer MS, Ramaswami G, Otto EA, Noriega TR, Seol AD, Robinson JF, Bennett CL, Josifova DJ, García-Verdugo JM, Katsanis N, Hildebrandt F, Reiter JF; ''A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.''; Nat Genet, 2011 PubMed Europe PMC Scholia
  97. Petroski MD, Deshaies RJ; ''Function and regulation of cullin-RING ubiquitin ligases.''; Nat Rev Mol Cell Biol, 2005 PubMed Europe PMC Scholia
  98. Taylor DR, Whitehouse IJ, Hooper NM; ''Glypican-1 mediates both prion protein lipid raft association and disease isoform formation.''; PLoS Pathog, 2009 PubMed Europe PMC Scholia
  99. Kendall KM, Rees E, Escott-Price V, Einon M, Thomas R, Hewitt J, O'Donovan MC, Owen MJ, Walters JTR, Kirov G; ''Cognitive Performance Among Carriers of Pathogenic Copy Number Variants: Analysis of 152,000 UK Biobank Subjects.''; Biol Psychiatry, 2017 PubMed Europe PMC Scholia
  100. Guo J, Wang D, Dong Y, Gao X, Tong H, Liu W, Zhang L, Sun M; ''ANO7: Insights into topology, function, and potential applications as a biomarker and immunotherapy target.''; Tissue Cell, 2021 PubMed Europe PMC Scholia
  101. Lao L, Shen J, Tian H, Yao Q, Li Y, Qian L, Murray SS, Wang JC; ''Secreted Phosphoprotein 24 kD Inhibits Growth of Human Prostate Cancer Cells Stimulated by BMP-2.''; Anticancer Res, 2016 PubMed Europe PMC Scholia
  102. Omi R, Kurokawa S, Mihara H, Hayashi H, Goto M, Miyahara I, Kurihara T, Hirotsu K, Esaki N; ''Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase.''; J Biol Chem, 2010 PubMed Europe PMC Scholia
  103. Kumar AS, Naruszewicz I, Wang P, Leung-Hagesteijn C, Hannigan GE; ''ILKAP regulates ILK signaling and inhibits anchorage-independent growth.''; Oncogene, 2004 PubMed Europe PMC Scholia
  104. Kang HJ, Lee MH, Kang HL, Kim SH, Ahn JR, Na H, Na TY, Kim YN, Seong JK, Lee MO; ''Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.''; Cancer Res, 2014 PubMed Europe PMC Scholia
  105. Schläfli P, Borter E, Spielmann P, Wenger RH; ''The PAS-domain kinase PASKIN: a new sensor in energy homeostasis.''; Cell Mol Life Sci, 2009 PubMed Europe PMC Scholia
  106. Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP; ''Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.''; Nature, 2002 PubMed Europe PMC Scholia
  107. Paul D, Bargale AB, Rapole S, Shetty PK, Santra MK; ''Protein Phosphatase 1 Regulatory Subunit SDS22 Inhibits Breast Cancer Cell Tumorigenesis by Functioning as a Negative Regulator of the AKT Signaling Pathway.''; Neoplasia, 2019 PubMed Europe PMC Scholia
  108. Schläfli P, Tröger J, Eckhardt K, Borter E, Spielmann P, Wenger RH; ''Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN.''; FEBS J, 2011 PubMed Europe PMC Scholia
  109. Balabanian K, Lagane B, Infantino S, Chow KY, Harriague J, Moepps B, Arenzana-Seisdedos F, Thelen M, Bachelerie F; ''The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
  110. Chaudhary SK, Iyyappan Y, Elayappan M, Jeyakanthan J, Sekar K; ''Insights into product release dynamics through structural analyses of thymidylate kinase.''; Int J Biol Macromol, 2019 PubMed Europe PMC Scholia
  111. Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA; ''YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.''; J Cell Biol, 2004 PubMed Europe PMC Scholia
  112. Gkika D, Lemonnier L, Shapovalov G, Gordienko D, Poux C, Bernardini M, Bokhobza A, Bidaux G, Degerny C, Verreman K, Guarmit B, Benahmed M, de Launoit Y, Bindels RJ, Fiorio Pla A, Prevarskaya N; ''TRP channel-associated factors are a novel protein family that regulates TRPM8 trafficking and activity.''; J Cell Biol, 2015 PubMed Europe PMC Scholia
  113. Huang DT, Ayrault O, Hunt HW, Taherbhoy AM, Duda DM, Scott DC, Borg LA, Neale G, Murray PJ, Roussel MF, Schulman BA; ''E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification.''; Mol Cell, 2009 PubMed Europe PMC Scholia
  114. Einsele-Scholz S, Malmsheimer S, Bertram K, Stehle D, Johänning J, Manz M, Daniel PT, Gillissen BF, Schulze-Osthoff K, Essmann F; ''Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak.''; J Cell Sci, 2016 PubMed Europe PMC Scholia
  115. Wilson WA, Skurat AV, Probst B, de Paoli-Roach A, Roach PJ, Rutter J; ''Control of mammalian glycogen synthase by PAS kinase.''; Proc Natl Acad Sci U S A, 2005 PubMed Europe PMC Scholia
  116. Seeger M, Kraft R, Ferrell K, Bech-Otschir D, Dumdey R, Schade R, Gordon C, Naumann M, Dubiel W; ''A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits.''; FASEB J, 1998 PubMed Europe PMC Scholia
  117. Na Z, Yeo SP, Bharath SR, Bowler MW, Balıkçı E, Wang CI, Song H; ''Structural basis for blocking PD-1-mediated immune suppression by therapeutic antibody pembrolizumab.''; Cell Res, 2017 PubMed Europe PMC Scholia
  118. Kuehl GE, Bigler J, Potter JD, Lampe JW; ''Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.''; Drug Metab Dispos, 2006 PubMed Europe PMC Scholia
  119. Fife BT, Pauken KE; ''The role of the PD-1 pathway in autoimmunity and peripheral tolerance.''; Ann N Y Acad Sci, 2011 PubMed Europe PMC Scholia
  120. Tanida I, Sou YS, Ezaki J, Minematsu-Ikeguchi N, Ueno T, Kominami E; ''HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
  121. Dunleavy EM, Roche D, Tagami H, Lacoste N, Ray-Gallet D, Nakamura Y, Daigo Y, Nakatani Y, Almouzni-Pettinotti G; ''HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.''; Cell, 2009 PubMed Europe PMC Scholia
  122. Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y; ''The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.''; Cell, 2003 PubMed Europe PMC Scholia
  123. Jääskeläinen M, Nieminen A, Pökkylä RM, Kauppinen M, Liakka A, Heikinheimo M, Vaskivuo TE, Klefström J, Tapanainen JS; ''Regulation of cell death in human fetal and adult ovaries--role of Bok and Bcl-X(L).''; Mol Cell Endocrinol, 2010 PubMed Europe PMC Scholia
  124. Takahashi T, Fournier A, Nakamura F, Wang LH, Murakami Y, Kalb RG, Fujisawa H, Strittmatter SM; ''Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.''; Cell, 1999 PubMed Europe PMC Scholia
  125. Lin SH; ''Prolactin-releasing peptide.''; Results Probl Cell Differ, 2008 PubMed Europe PMC Scholia
  126. Shen K, Choe A, Sabatini DM; ''Intersubunit Crosstalk in the Rag GTPase Heterodimer Enables mTORC1 to Respond Rapidly to Amino Acid Availability.''; Mol Cell, 2017 PubMed Europe PMC Scholia
  127. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR; ''Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.''; Mol Med, 2010 PubMed Europe PMC Scholia
  128. Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, Dubiel W; ''COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system.''; EMBO J, 2001 PubMed Europe PMC Scholia
  129. Lépine J, Bernard O, Plante M, Têtu B, Pelletier G, Labrie F, Bélanger A, Guillemette C; ''Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.''; J Clin Endocrinol Metab, 2004 PubMed Europe PMC Scholia
  130. Ling L, Goeddel DV; ''MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network.''; J Biol Chem, 2000 PubMed Europe PMC Scholia
  131. Nerstedt A, Cansby E, Andersson CX, Laakso M, Stan�áková A, Blüher M, Smith U, Mahlapuu M; ''Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle.''; Diabetologia, 2012 PubMed Europe PMC Scholia
  132. Li M, Chen X, Ye QZ, Vogt A, Yin XM; ''A high-throughput FRET-based assay for determination of Atg4 activity.''; Autophagy, 2012 PubMed Europe PMC Scholia
  133. Bar-Peled L, Schweitzer LD, Zoncu R, Sabatini DM; ''Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.''; Cell, 2012 PubMed Europe PMC Scholia
  134. Marchese A, Heiber M, Nguyen T, Heng HH, Saldivia VR, Cheng R, Murphy PM, Tsui LC, Shi X, Gregor P; ''Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors.''; Genomics, 1995 PubMed Europe PMC Scholia
  135. Suriano AR, Sanford AN, Kim N, Oh M, Kennedy S, Henderson MJ, Dietzmann K, Sullivan KE; ''GCF2/LRRFIP1 represses tumor necrosis factor alpha expression.''; Mol Cell Biol, 2005 PubMed Europe PMC Scholia
  136. Seyrantepe V, Landry K, Trudel S, Hassan JA, Morales CR, Pshezhetsky AV; ''Neu4, a novel human lysosomal lumen sialidase, confers normal phenotype to sialidosis and galactosialidosis cells.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
  137. Deshaies RJ, Joazeiro CA; ''RING domain E3 ubiquitin ligases.''; Annu Rev Biochem, 2009 PubMed Europe PMC Scholia
  138. Kim YM, Stone M, Hwang TH, Kim YG, Dunlevy JR, Griffin TJ, Kim DH; ''SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.''; Mol Cell, 2012 PubMed Europe PMC Scholia
  139. von Thun A, Birtwistle M, Kalna G, Grindlay J, Strachan D, Kolch W, von Kriegsheim A, Norman JC; ''ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.''; J Cell Sci, 2012 PubMed Europe PMC Scholia
  140. Levoye A, Balabanian K, Baleux F, Bachelerie F, Lagane B; ''CXCR7 heterodimerizes with CXCR4 and regulates CXCL12-mediated G protein signaling.''; Blood, 2009 PubMed Europe PMC Scholia
  141. Struys EA, Korman SH, Salomons GS, Darmin PS, Achouri Y, van Schaftingen E, Verhoeven NM, Jakobs C; ''Mutations in phenotypically mild D-2-hydroxyglutaric aciduria.''; Ann Neurol, 2005 PubMed Europe PMC Scholia
  142. Picard N, Ratanasavanh D, Prémaud A, Le Meur Y, Marquet P; ''Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.''; Drug Metab Dispos, 2005 PubMed Europe PMC Scholia
  143. Wei SM, Xie CG, Abe Y, Cai JT; ''ADP-ribosylation factor like 7 (ARL7) interacts with alpha-tubulin and modulates intracellular vesicular transport.''; Biochem Biophys Res Commun, 2009 PubMed Europe PMC Scholia
  144. Preisinger C, Short B, De Corte V, Bruyneel E, Haas A, Kopajtich R, Gettemans J, Barr FA; ''''; , PubMed Europe PMC Scholia
  145. Hoefs SJ, van Spronsen FJ, Lenssen EW, Nijtmans LG, Rodenburg RJ, Smeitink JA, van den Heuvel LP; ''NDUFA10 mutations cause complex I deficiency in a patient with Leigh disease.''; Eur J Hum Genet, 2011 PubMed Europe PMC Scholia
  146. Rikiyama T, Curtis J, Oikawa M, Zimonjic DB, Popescu N, Murphy BA, Wilson MA, Johnson AC; ''GCF2: expression and molecular analysis of repression.''; Biochim Biophys Acta, 2003 PubMed Europe PMC Scholia
  147. Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E; ''Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease.''; Haematologica, 2018 PubMed Europe PMC Scholia
  148. Ohmura-Hoshino M, Goto E, Matsuki Y, Aoki M, Mito M, Uematsu M, Hotta H, Ishido S; ''A novel family of membrane-bound E3 ubiquitin ligases.''; J Biochem, 2006 PubMed Europe PMC Scholia
  149. Ku B, Hong W, Keum CW, Kim M, Ryu H, Jeon D, Shin HC, Kim JH, Kim SJ, Ryu SE; ''Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28.''; PLoS One, 2017 PubMed Europe PMC Scholia
  150. Engel T, Lueken A, Bode G, Hobohm U, Lorkowski S, Schlueter B, Rust S, Cullen P, Pech M, Assmann G, Seedorf U; ''ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export.''; FEBS Lett, 2004 PubMed Europe PMC Scholia
  151. Wurst W, Bally-Cuif L; ''Neural plate patterning: upstream and downstream of the isthmic organizer.''; Nat Rev Neurosci, 2001 PubMed Europe PMC Scholia
  152. Miret JJ, Rakhilina L, Silverman L, Oehlen B; ''Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  153. De Simone G, di Masi A, Vita GM, Polticelli F, Pesce A, Nardini M, Bolognesi M, Ciaccio C, Coletta M, Turilli ES, Fasano M, Tognaccini L, Smulevich G, Abbruzzetti S, Viappiani C, Bruno S, Ascenzi P; ''Mycobacterial and Human Nitrobindins: Structure and Function.''; Antioxid Redox Signal, 2020 PubMed Europe PMC Scholia
  154. Sugawara K, Suzuki NN, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F; ''Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
  155. Lyapina S, Cope G, Shevchenko A, Serino G, Tsuge T, Zhou C, Wolf DA, Wei N, Deshaies RJ; ''Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome.''; Science, 2001 PubMed Europe PMC Scholia
  156. Goolsby KM, Shapiro DJ; ''RNAi-mediated depletion of the 15 KH domain protein, vigilin, induces death of dividing and non-dividing human cells but does not initially inhibit protein synthesis.''; Nucleic Acids Res, 2003 PubMed Europe PMC Scholia
  157. Murai T, Samata N, Iwabuchi H, Ikeda T; ''Human UDP-glucuronosyltransferase, UGT1A8, glucuronidates dihydrotestosterone to a monoglucuronide and further to a structurally novel diglucuronide.''; Drug Metab Dispos, 2006 PubMed Europe PMC Scholia
  158. Berger KN, Pu JJ; ''PD-1 pathway and its clinical application: A 20year journey after discovery of the complete human PD-1 gene.''; Gene, 2018 PubMed Europe PMC Scholia
  159. Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T; ''LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation.''; J Cell Sci, 2004 PubMed Europe PMC Scholia
  160. Toyofuku T, Yoshida J, Sugimoto T, Zhang H, Kumanogoh A, Hori M, Kikutani H; ''FARP2 triggers signals for Sema3A-mediated axonal repulsion.''; Nat Neurosci, 2005 PubMed Europe PMC Scholia
  161. Ishibashi K; ''New members of mammalian aquaporins: AQP10-AQP12.''; Handb Exp Pharmacol, 2009 PubMed Europe PMC Scholia
  162. Sun D, Zhang J, Xie J, Wei W, Chen M, Zhao X; ''MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.''; FEBS Lett, 2012 PubMed Europe PMC Scholia
  163. Picollo A, Malvezzi M, Accardi A; ''TMEM16 proteins: unknown structure and confusing functions.''; J Mol Biol, 2015 PubMed Europe PMC Scholia
  164. Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T; ''The crystal structure of human Atg4b, a processing andde-conjugating enzyme for autophagosome-forming modifiers.''; J Mol Biol, 2006 PubMed Europe PMC Scholia
  165. Li Y, Zhang Y, Wang L, Wang P, Xue Y, Li X, Qiao X, Zhang X, Xu T, Liu G, Li P, Chen C; ''Autophagy impairment mediated by S-nitrosation of ATG4B leads to neurotoxicity in response to hyperglycemia.''; Autophagy, 2017 PubMed Europe PMC Scholia
  166. Joseph TB, Wang SW, Liu X, Kulkarni KH, Wang J, Xu H, Hu M; ''Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.''; Mol Pharm, 2007 PubMed Europe PMC Scholia
  167. Chengxiao Z, Ze Y; ''Biological function and molecular mechanism of Twist2.''; Yi Chuan, 2015 PubMed Europe PMC Scholia
  168. Hirbawi J, Bialkowska K, Bledzka KM, Liu J, Fukuda K, Qin J, Plow EF; ''The extreme C-terminal region of kindlin-2 is critical to its regulation of integrin activation.''; J Biol Chem, 2017 PubMed Europe PMC Scholia
  169. Spåhr H, Habermann B, Gustafsson CM, Larsson NG, Hallberg BM; ''Structure of the human MTERF4-NSUN4 protein complex that regulates mitochondrial ribosome biogenesis.''; Proc Natl Acad Sci U S A, 2012 PubMed Europe PMC Scholia
  170. Agrotis A, Pengo N, Burden JJ, Ketteler R; ''Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.''; Autophagy, 2019 PubMed Europe PMC Scholia
  171. Ray JE, Garcia J, Jurisicova A, Caniggia I; ''Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia.''; Cell Death Differ, 2010 PubMed Europe PMC Scholia
  172. Bocharov AV, Vishnyakova TG, Baranova IN, Patterson AP, Eggerman TL; ''Characterization of a 95 kDa high affinity human high density lipoprotein-binding protein.''; Biochemistry, 2001 PubMed Europe PMC Scholia
  173. Tang L, Singh R, Liu Z, Hu M; ''Structure and concentration changes affect characterization of UGT isoform-specific metabolism of isoflavones.''; Mol Pharm, 2009 PubMed Europe PMC Scholia
  174. Sakane F, Imai S, Yamada K, Murakami T, Tsushima S, Kanoh H; ''Alternative splicing of the human diacylglycerol kinase delta gene generates two isoforms differing in their expression patterns and in regulatory functions.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  175. Achouri Y, Noël G, Vertommen D, Rider MH, Veiga-Da-Cunha M, Van Schaftingen E; ''Identification of a dehydrogenase acting on D-2-hydroxyglutarate.''; Biochem J, 2004 PubMed Europe PMC Scholia
  176. De Simone G, di Masi A, Polticelli F, Ascenzi P; ''Human nitrobindin: the first example of an all-β-barrel ferric heme-protein that catalyzes peroxynitrite detoxification.''; FEBS Open Bio, 2018 PubMed Europe PMC Scholia
  177. Takegahara N, Kang S, Nojima S, Takamatsu H, Okuno T, Kikutani H, Toyofuku T, Kumanogoh A; ''Integral roles of a guanine nucleotide exchange factor, FARP2, in osteoclast podosome rearrangements.''; FASEB J, 2010 PubMed Europe PMC Scholia
  178. Hatakeyama S, Nakayama KI; ''U-box proteins as a new family of ubiquitin ligases.''; Biochem Biophys Res Commun, 2003 PubMed Europe PMC Scholia
  179. Rümenapp U, Blomquist A, Schwörer G, Schablowski H, Psoma A, Jakobs KH; ''Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member.''; FEBS Lett, 1999 PubMed Europe PMC Scholia
  180. Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, Wei K, McMaster BE, Wright K, Howard MC, Schall TJ; ''A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.''; J Exp Med, 2006 PubMed Europe PMC Scholia
  181. Agrotis A, von Chamier L, Oliver H, Kiso K, Singh T, Ketteler R; ''Human ATG4 autophagy proteases counteract attachment of ubiquitin-like LC3/GABARAP proteins to other cellular proteins.''; J Biol Chem, 2019 PubMed Europe PMC Scholia
  182. Bidaux G, Beck B, Zholos A, Gordienko D, Lemonnier L, Flourakis M, Roudbaraki M, Borowiec AS, Fernández J, Delcourt P, Lepage G, Shuba Y, Skryma R, Prevarskaya N; ''Regulation of activity of transient receptor potential melastatin 8 (TRPM8) channel by its short isoforms.''; J Biol Chem, 2012 PubMed Europe PMC Scholia
  183. Johansson AL, Collins R, Arnér ES, Brzezinski P, Högbom M; ''Biochemical discrimination between selenium and sulfur 2: mechanistic investigation of the selenium specificity of human selenocysteine lyase.''; PLoS One, 2012 PubMed Europe PMC Scholia
  184. Pengo N, Agrotis A, Prak K, Jones J, Ketteler R; ''A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B.''; Nat Commun, 2017 PubMed Europe PMC Scholia
  185. Honda H, Kobayashi Y, Onuma S, Shibagaki K, Yuza T, Hirao K, Yamamoto T, Tomosugi N, Shibata T; ''Associations among Erythroferrone and Biomarkers of Erythropoiesis and Iron Metabolism, and Treatment with Long-TermErythropoiesis-Stimulating Agents in Patients on Hemodialysis.''; PLoS One, 2016 PubMed Europe PMC Scholia
  186. Wang AH, Bertos NR, Vezmar M, Pelletier N, Crosato M, Heng HH, Th'ng J, Han J, Yang XJ; ''HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.''; Mol Cell Biol, 1999 PubMed Europe PMC Scholia
  187. Satoo K, Noda NN, Kumeta H, Fujioka Y, Mizushima N, Ohsumi Y, Inagaki F; ''The structure of Atg4B-LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy.''; EMBO J, 2009 PubMed Europe PMC Scholia
  188. Kalatskaya I, Berchiche YA, Gravel S, Limberg BJ, Rosenbaum JS, Heveker N; ''AMD3100 is a CXCR7 ligand with allosteric agonist properties.''; Mol Pharmacol, 2009 PubMed Europe PMC Scholia
  189. Lee MS, Lowe G, Flanagan S, Kuchler K, Glackin CA; ''Human Dermo-1 has attributes similar to twist in early bone development.''; Bone, 2000 PubMed Europe PMC Scholia
  190. Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R; ''A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.''; J Leukoc Biol, 2008 PubMed Europe PMC Scholia
  191. An R, da Silva Xavier G, Hao HX, Semplici F, Rutter J, Rutter GA; ''Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic beta-cells.''; Biochem Soc Trans, 2006 PubMed Europe PMC Scholia
  192. Arrington DD, Van Vleet TR, Schnellmann RG; ''Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction.''; Am J Physiol Cell Physiol, 2006 PubMed Europe PMC Scholia
  193. Shen K, Sabatini DM; ''Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms.''; Proc Natl Acad Sci U S A, 2018 PubMed Europe PMC Scholia
  194. Lalonde ME, Avvakumov N, Glass KC, Joncas FH, Saksouk N, Holliday M, Paquet E, Yan K, Tong Q, Klein BJ, Tan S, Yang XJ, Kutateladze TG, Côté J; ''Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity.''; Genes Dev, 2013 PubMed Europe PMC Scholia
  195. Lee LS, Cheng Y; ''Human thymidylate kinase. Purification, characterization, and kinetic behavior of the thymidylate kinase derived from chronic myelocytic leukemia.''; J Biol Chem, 1977 PubMed Europe PMC Scholia
  196. Kohda M, Tokuzawa Y, Kishita Y, Nyuzuki H, Moriyama Y, Mizuno Y, Hirata T, Yatsuka Y, Yamashita-Sugahara Y, Nakachi Y, Kato H, Okuda A, Tamaru S, Borna NN, Banshoya K, Aigaki T, Sato-Miyata Y, Ohnuma K, Suzuki T, Nagao A, Maehata H, Matsuda F, Higasa K, Nagasaki M, Yasuda J, Yamamoto M, Fushimi T, Shimura M, Kaiho-Ichimoto K, Harashima H, Yamazaki T, Mori M, Murayama K, Ohtake A, Okazaki Y; ''A Comprehensive Genomic Analysis Reveals the Genetic Landscape of Mitochondrial Respiratory Chain Complex Deficiencies.''; PLoS Genet, 2016 PubMed Europe PMC Scholia
  197. Delprat B, Boulanger A, Wang J, Beaudoin V, Guitton MJ, Ventéo S, Dechesne CJ, Pujol R, Lavigne-Rebillard M, Puel JL, Hamel CP; ''Downregulation of otospiralin, a novel inner ear protein, causes hair cell degeneration and deafness.''; J Neurosci, 2002 PubMed Europe PMC Scholia
  198. Kawasaki T, Kobayashi T, Ueyama T, Shirai Y, Saito N; ''Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha.''; Biochem J, 2008 PubMed Europe PMC Scholia
  199. Misra VK, Struys EA, O'brien W, Salomons GS, Glover T, Jakobs C, Innis JW; ''Phenotypic heterogeneity in the presentation of D-2-hydroxyglutaric aciduria in monozygotic twins.''; Mol Genet Metab, 2005 PubMed Europe PMC Scholia
  200. Seo JH, Park JH, Lee EJ, Vo TT, Choi H, Kim JY, Jang JK, Wee HJ, Lee HS, Jang SH, Park ZY, Jeong J, Lee KJ, Seok SH, Park JY, Lee BJ, Lee MN, Oh GT, Kim KW; ''ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.''; Nat Commun, 2016 PubMed Europe PMC Scholia
  201. Cheng F, Cappai R, Ciccotosto GD, Svensson G, Multhaup G, Fransson LÃ…, Mani K; ''Suppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation.''; J Biol Chem, 2011 PubMed Europe PMC Scholia
  202. Morris JA, Kandpal G, Ma L, Austin CP; ''DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation.''; Hum Mol Genet, 2003 PubMed Europe PMC Scholia
  203. Yamaguchi K, Hata K, Koseki K, Shiozaki K, Akita H, Wada T, Moriya S, Miyagi T; ''Evidence for mitochondrial localization of a novel human sialidase (NEU4).''; Biochem J, 2005 PubMed Europe PMC Scholia
  204. Kuo YC, Shen YR, Chen HI, Lin YH, Wang YY, Chen YR, Wang CY, Kuo PL; ''SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins.''; J Cell Sci, 2015 PubMed Europe PMC Scholia
  205. Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, Horn L, Drake CG, Pardoll DM, Chen L, Sharfman WH, Anders RA, Taube JM, McMiller TL, Xu H, Korman AJ, Jure-Kunkel M, Agrawal S, McDonald D, Kollia GD, Gupta A, Wigginton JM, Sznol M; ''Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.''; N Engl J Med, 2012 PubMed Europe PMC Scholia
  206. Mani K, Cheng F, Havsmark B, Jönsson M, Belting M, Fransson LA; ''Prion, amyloid beta-derived Cu(II) ions, or free Zn(II) ions support S-nitroso-dependent autocleavage of glypican-1 heparan sulfate.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
  207. Zhao CL, Hui Y, Wang LJ, Yang D, Yakirevich E, Mangray S, Huang CK, Lu S; ''Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.''; Hum Pathol, 2018 PubMed Europe PMC Scholia
  208. Goll DE, Thompson VF, Li H, Wei W, Cong J; ''The calpain system.''; Physiol Rev, 2003 PubMed Europe PMC Scholia
  209. Danelon V, Goldner R, Martinez E, Gokhman I, Wang K, Yaron A, Tran TS; ''Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis.''; J Neurosci, 2020 PubMed Europe PMC Scholia
  210. Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim WS, Park SP, Lee J, Lee B, Kim BM, Raouf R, Shin YK, Oh U; ''TMEM16A confers receptor-activated calcium-dependent chloride conductance.''; Nature, 2008 PubMed Europe PMC Scholia
  211. Cuthbert EJ, Davis KK, Casanova JE; ''Substrate specificities and activities of AZAP family Arf GAPs in vivo.''; Am J Physiol Cell Physiol, 2008 PubMed Europe PMC Scholia
  212. Daher R, Van Lente F; ''Characterization of selenocysteine lyase in human tissues and its relationship to tissue selenium concentrations.''; J Trace Elem Electrolytes Health Dis, 1992 PubMed Europe PMC Scholia
  213. Müller PM, Rademacher J, Bagshaw RD, Wortmann C, Barth C, van Unen J, Alp KM, Giudice G, Eccles RL, Heinrich LE, Pascual-Vargas P, Sanchez-Castro M, Brandenburg L, Mbamalu G, Tucholska M, Spatt L, Czajkowski MT, Welke RW, Zhang S, Nguyen V, Rrustemi T, Trnka P, Freitag K, Larsen B, Popp O, Mertins P, Gingras AC, Roth FP, Colwill K, Bakal C, Pertz O, Pawson T, Petsalaki E, Rocks O; ''Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.''; Nat Cell Biol, 2020 PubMed Europe PMC Scholia
  214. Tan S, Zhang H, Chai Y, Song H, Tong Z, Wang Q, Qi J, Wong G, Zhu X, Liu WJ, Gao S, Wang Z, Shi Y, Yang F, Gao GF, Yan J; ''An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.''; Nat Commun, 2017 PubMed Europe PMC Scholia
  215. Makeyeva Y, Nicol C, Ledger WL, Ryugo DK; ''Immunocytochemical Localization of Olfactory-signaling Molecules in Human and Rat Spermatozoa.''; J Histochem Cytochem, 2020 PubMed Europe PMC Scholia
  216. Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN; ''A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.''; Sci Rep, 2018 PubMed Europe PMC Scholia
  217. Kranendijk M, Struys EA, Gibson KM, Wickenhagen WV, Abdenur JE, Buechner J, Christensen E, de Kremer RD, Errami A, Gissen P, Gradowska W, Hobson E, Islam L, Korman SH, Kurczynski T, Maranda B, Meli C, Rizzo C, Sansaricq C, Trefz FK, Webster R, Jakobs C, Salomons GS; ''Evidence for genetic heterogeneity in D-2-hydroxyglutaric aciduria.''; Hum Mutat, 2010 PubMed Europe PMC Scholia
  218. Chamorro-Jorganes A, Araldi E, Rotllan N, Cirera-Salinas D, Suárez Y; ''Autoregulation of glypican-1 by intronic microRNA-149 fine tunes the angiogenic response to FGF2 in human endothelial cells.''; J Cell Sci, 2014 PubMed Europe PMC Scholia
  219. Spiliotis ET, Kinoshita M, Nelson WJ; ''A mitotic septin scaffold required for Mammalian chromosome congression and segregation.''; Science, 2005 PubMed Europe PMC Scholia
  220. Vuori K, Pihlajaniemi T, Marttila M, Kivirikko KI; ''Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system.''; Proc Natl Acad Sci U S A, 1992 PubMed Europe PMC Scholia
  221. Leung-Hagesteijn C, Mahendra A, Naruszewicz I, Hannigan GE; ''Modulation of integrin signal transduction by ILKAP, a protein phosphatase 2C associating with the integrin-linked kinase, ILK1.''; EMBO J, 2001 PubMed Europe PMC Scholia
  222. Liefhebber JM, Punt S, Spaan WJ, van Leeuwen HC; ''The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein.''; BMC Cell Biol, 2010 PubMed Europe PMC Scholia
  223. Jeong DG, Wei CH, Ku B, Jeon TJ, Chien PN, Kim JK, Park SY, Hwang HS, Ryu SY, Park H, Kim DS, Kim SJ, Ryu SE; ''The family-wide structure and function of human dual-specificity protein phosphatases.''; Acta Crystallogr D Biol Crystallogr, 2014 PubMed Europe PMC Scholia
  224. Struys EA, Salomons GS, Achouri Y, Van Schaftingen E, Grosso S, Craigen WJ, Verhoeven NM, Jakobs C; ''Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria.''; Am J Hum Genet, 2005 PubMed Europe PMC Scholia
  225. Netter P, Chan SK, Banerjee PP, Monaco-Shawver L, Noroski LM, Hanson IC, Forbes LR, Mace EM, Chinen J, Gaspar HB, Sleiman P, Hakonarson H, Klein C, Ehlayel MS, Orange JS; ''A novel Rab27a mutation binds melanophilin, but not Munc13-4, causing immunodeficiency without albinism.''; J Allergy Clin Immunol, 2016 PubMed Europe PMC Scholia
  226. Kremer BE, Adang LA, Macara IG; ''Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.''; Cell, 2007 PubMed Europe PMC Scholia
  227. Yano T; ''The energy-transducing NADH: quinone oxidoreductase,complex I.''; Mol Aspects Med, 2002 PubMed Europe PMC Scholia
  228. Pasricha SR, McHugh K, Drakesmith H; ''Regulation of Hepcidin by Erythropoiesis: The Story So Far.''; Annu Rev Nutr, 2016 PubMed Europe PMC Scholia
  229. Itäaho K, Mackenzie PI, Ikushiro S, Miners JO, Finel M; ''The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.''; Drug Metab Dispos, 2008 PubMed Europe PMC Scholia
  230. Holubová M, Hrubá L, Neprašová B, Majer�íková Z, Lacinová Z, Kuneš J, Maletínská L, Železná B; ''Prolactin-releasing peptide improved leptin hypothalamic signaling in obese mice.''; J Mol Endocrinol, 2018 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134653view09:17, 24 July 2024EgonwAdded the missing datasources for three OMIM identifiers
134545view21:33, 22 July 2024EweitzStandardize case
134525view12:56, 22 July 2024EweitzOntology Term : 'chromosome 2q37 deletion syndrome' added !
134524view12:55, 22 July 2024EweitzOntology Term : 'chromosomal duplication syndrome' added !
134523view12:55, 22 July 2024EweitzOntology Term : 'chromosomal deletion syndrome' added !
134522view12:55, 22 July 2024EweitzOntology Term : 'disease of mental health' added !
134521view12:54, 22 July 2024EweitzEconomize layout
134520view12:53, 22 July 2024EweitzRefine legend, economize layout
134498view05:50, 22 July 2024EgonwAdded the missing Complex Portal for identifiers from this database
134497view05:46, 22 July 2024EgonwRemoved a template comment
127064view15:58, 26 July 2023FehrhartModified description
127063view15:56, 26 July 2023FehrhartAdded information on chromosomal location found in the Kirov et al. 2014 paper
122740view13:12, 7 May 2022Shad4Added neuropathologies
122633view10:56, 22 April 2022FehrhartOntology Term : 'disease pathway' added !
122627view09:58, 22 April 2022Shad4Modified description
122603view18:31, 20 April 2022Shad4Connected unconnected lines
122575view19:05, 16 April 2022Shad4New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(R)-2-hydroxyglutarateMetaboliteCHEBI:15801 (ChEBI)
1,2-diacyl-sn-glycerolsMetaboliteCHEBI:17815 (ChEBI)
2-oxoglutarateMetaboliteCHEBI:16810 (ChEBI)
ABCA1ProteinENSG00000165029 (Ensembl)
ACKR3GeneProductENSG00000144476 (Ensembl)
AGAP1-IT1GeneProductENSG00000235529 (Ensembl)
AGAP1GeneProductENSG00000157985 (Ensembl)
AGXTGeneProductENSG00000172482 (Ensembl)
ANKMY1GeneProductENSG00000144504 (Ensembl)
ANO7GeneProductENSG00000146205 (Ensembl)
AQP12AProteinENSG00000184945 (Ensembl)
AQP12BProteinENSG00000185176 (Ensembl)
ARF1ProteinENSG00000143761 (Ensembl)
ARF5ProteinENSG00000004059 (Ensembl)
ARL4CProteinENSG00000188042 (Ensembl)
ASB18GeneProductENSG00000182177 (Ensembl)
ASB1GeneProductENSG00000065802 (Ensembl)
ASCL1ProteinENSG00000139352 (Ensembl)
ATG4BGeneProductENSG00000168397 (Ensembl)
Alzheimer disease
Amino acids regulate mTORC1PathwayWP5015 (WikiPathways)
ApoptosisPathwayWP254 (WikiPathways)
BOK-AS1GeneProductENSG00000234235 (Ensembl)
BOKGeneProductENSG00000176720 (Ensembl)
C2orf54GeneProductENSG00000172478 (Ensembl)
CALCAProteinENSG00000110680 (Ensembl)
CALCRLGeneProductENSG00000064989 (Ensembl)
CALM1ProteinENSG00000198668 (Ensembl)
CAPN10-AS1GeneProductENSG00000260942 (Ensembl)
CAPN10GeneProductENSG00000142330 (Ensembl)
CENP-A nucleosome complexComplexCPX-5647
CENPAProteinENSG00000115163 (Ensembl)
CFLARProteinENSG00000003402 (Ensembl)
CICP10GeneProductENSG00000224160 (Ensembl)
COL6A3GeneProductENSG00000163359 (Ensembl)
COP9 signalosome variant 1ComplexCPX-1870
COP9 signalosomeComplexCPX-1870
COPS8GeneProductENSG00000198612 (Ensembl)
CXCL11ProteinENSG00000169248 (Ensembl)
CXCL12ProteinENSG00000107562 (Ensembl)
CXCR4ProteinENSG00000121966 (Ensembl)
CXXC11GeneProductENSG00000188011 (Ensembl)
CYTH1ProteinENSG00000108669 (Ensembl)
CYTH2ProteinENSG00000105443 (Ensembl)
CYTH3ProteinENSG00000008256 (Ensembl)
CYTH4ProteinENSG00000100055 (Ensembl)
Ca2+MetaboliteCHEBI:29108 (ChEBI)
Cancer immunotherapy by PD-1 blockadePathwayWP4585 (WikiPathways)
Cell junction organizationPathwayWP1793 (WikiPathways)
Cilium AssemblyPathwayWP4124 (WikiPathways)
Circadian ClockPathwayWP1797 (WikiPathways)
Citric acid cycle and respiratory electron transport PathwayWP2766 (WikiPathways)
D-2-HYDROXYGLUTARIC ACIDURIA 1; D2HGA1600721
D2HGDHGeneProductENSG00000180902 (Ensembl)
DGKDGeneProductENSG00000077044 (Ensembl)
DISC1ProteinENSG00000162946 (Ensembl)
DNAJB3GeneProductENSG00000227802 (Ensembl)
DTYMKGeneProductENSG00000168393 (Ensembl)
DUSP28GeneProductENSG00000188542 (Ensembl)
Degradation of the extracellular matrixPathwayWP2774 (WikiPathways)
EEF1A1ProteinENSG00000156508 (Ensembl)
EGFRProteinENSG00000146648 (Ensembl)
ESPNLGeneProductENSG00000144488 (Ensembl)
Electron transport chain: OXPHOS system in mitochondriaPathwayWP111 (WikiPathways)
Endothelin pathwaysPathwayWP2197 (WikiPathways)
Estrogen metabolismPathwayWP697 (WikiPathways)
FAM132BGeneProductENSG00000178752 (Ensembl)
FARP2GeneProductENSG00000006607 (Ensembl)
Factors and pathways affecting

insulin-like growth factor

(IGF1)-Akt signaling		PathwayWP3850 (WikiPathways)
Filament-forming complexComplex
G protein signaling pathwaysPathwayWP35 (WikiPathways)
GABARAPProteinENSG00000170296 (Ensembl)
GABARAPL1ProteinENSG00000139112 (Ensembl)
GABARAPL2ProteinENSG00000034713 (Ensembl)
GAL3ST2GeneProductENSG00000154252 (Ensembl)
GBX2GeneProductENSG00000168505 (Ensembl)
GDPMetaboliteCHEBI:17552 (ChEBI)
GMEB1ProteinENSG00000162419 (Ensembl)
GPC1GeneProductENSG00000063660 (Ensembl)
GPR35GeneProductENSG00000178623 (Ensembl)
GTPMetaboliteCHEBI:37565 (ChEBI)
GYS1ProteinENSG00000104812 (Ensembl)
Glycogen synthesis and degradationPathwayWP500 (WikiPathways)
H2OMetaboliteCHEBI:15377 (ChEBI)
HAMPProteinENSG00000105697 (Ensembl)
HBO1-5.1 histone acetyltransferase complexComplexCPX-721
HDAC4GeneProductENSG00000068024 (Ensembl)
HDLBPGeneProductENSG00000115677 (Ensembl)
HES1ProteinENSG00000114315 (Ensembl)
HES6GeneProductENSG00000144485 (Ensembl)
HJURPGeneProductENSG00000123485 (Ensembl)
HSPE1P9GeneProductENSG00000232690 (Ensembl)
IL13RA1ProteinENSG00000131724 (Ensembl)
IL1BProteinENSG00000125538 (Ensembl)
ILKAPGeneProductENSG00000132323 (Ensembl)
ILKProteinENSG00000166333 (Ensembl)
ING5GeneProductENSG00000168395 (Ensembl)
IQCA1GeneProductENSG00000132321 (Ensembl)
IRF8ProteinENSG00000140968 (Ensembl)
ITGB3ProteinENSG00000259207 (Ensembl)
ITPK1ProteinENSG00000100605 (Ensembl)
Integrin signalingPathwayWP4431 (WikiPathways)
Integrin-mediated cell adhesionPathwayWP185 (WikiPathways)
Interleukin-4 and Interleukin-13 signalingPathwayWP4066 (WikiPathways)
JUNProteinENSG00000177606 (Ensembl)
KIF1AGeneProductENSG00000130294 (Ensembl)
KLHL30GeneProductENSG00000168427 (Ensembl)
L-alanineMetaboliteCHEBI:57972 (ChEBI)
L-selenocysteineMetaboliteCHEBI:57843 (ChEBI)
LINC01107GeneProductENSG00000225493 (Ensembl)
LRRFIP1GeneProductENSG00000124831 (Ensembl)
MAP1LC3AProteinENSG00000101460 (Ensembl)
MAP1LC3BProteinENSG00000140941 (Ensembl)
MAP1LC3CProteinENSG00000197769 (Ensembl)
MAP4ProteinENSG00000047849 (Ensembl)
MAPK cascadePathwayWP422 (WikiPathways)
MEF2AProteinENSG00000068305 (Ensembl)
MEF2CProteinENSG00000081189 (Ensembl)
MIR149GeneProductENSG00000207611 (Ensembl)
MIR2467GeneProductENSG00000264292 (Ensembl)
MIR3133GeneProductENSG00000263752 (Ensembl)
MIR4269GeneProductENSG00000265215 (Ensembl)
MIR4440GeneProductENSG00000266109 (Ensembl)
MIR4441GeneProductENSG00000264810 (Ensembl)
MIR4786GeneProductENSG00000264279 (Ensembl)
MITOCHONDRIAL COMPLEX I DEFICIENCY, NUCLEAR TYPE 22; MC1DN22618243
MLPHProteinENSG00000115648 (Ensembl)
MOZ1 histone acetyltransferase complexComplexCPX-727
MROH2AGeneProductENSG00000185038 (Ensembl)
MSL3P1GeneProductENSG00000224287 (Ensembl)
MTERFD2GeneProductENSG00000122085 (Ensembl)
MYEOV2GeneProductENSG00000172428 (Ensembl)
MYO5AProteinENSG00000197535 (Ensembl)
MYOD1ProteinENSG00000129152 (Ensembl)
MYOGProteinENSG00000122180 (Ensembl)
MacroautophagyPathwayWP3348 (WikiPathways)
Metapathway

biotransformation

Phase I and II		PathwayWP702 (WikiPathways)
Metapathway biotransformation Phase I and IIPathwayWP702 (WikiPathways)
Mitochondrial respiratory chain complex IComplexCPX-577
MyogenesisPathwayWP1865 (WikiPathways)
NDUFA10GeneProductENSG00000130414 (Ensembl)
NEDD8ProteinENSG00000129559 (Ensembl)
NEU4GeneProductENSG00000204099 (Ensembl)
NEUROPATHOLOGY
NFKBIAProteinENSG00000100906 (Ensembl)
Na+MetaboliteCHEBI:29101 (ChEBI)
NeddylationPathwayWP4121 (WikiPathways)
Neural crest differentiationPathwayWP2064 (WikiPathways)
OR5S1PGeneProductENSG00000213048 (Ensembl)
OR6B2GeneProductENSG00000182083 (Ensembl)
OR6B3GeneProductENSG00000178586 (Ensembl)
OR9S24PGeneProductENSG00000231278 (Ensembl)
OTOSGeneProductENSG00000178602 (Ensembl)
Olfactory receptor activityPathwayWP3608 (WikiPathways)
PASKGeneProductENSG00000115687 (Ensembl)
PDCD1GeneProductENSG00000188389 (Ensembl)
PDGFAProteinENSG00000197461 (Ensembl)
PDX1ProteinENSG00000139515 (Ensembl)
PER2GeneProductENSG00000132326 (Ensembl)
PIP2MetaboliteCHEBI:18348 (ChEBI)
PIP3MetaboliteCHEBI:16618 (ChEBI)
PPP1R7GeneProductENSG00000115685 (Ensembl)
PRLProteinENSG00000172179 (Ensembl)
PRLHGeneProductENSG00000071677 (Ensembl)
PRR21GeneProductENSG00000260610 (Ensembl)
Phosphatidic acidMetaboliteCHEBI:58608 (ChEBI)
Prolactin receptor signalingPathwayWP2678 (WikiPathways)
ProteinProtein
Protein phosphatase 1Complex
Protein ubiquitinationPathwayWP4125 (WikiPathways)
Protein-tyrosine-phosphatase10684 (Rhea)
RAB17GeneProductENSG00000124839 (Ensembl)
RAB27AProteinENSG00000069974 (Ensembl)
RAC1ProteinENSG00000136238 (Ensembl)
RAMP1GeneProductENSG00000132329 (Ensembl)
RBM44GeneProductENSG00000177483 (Ensembl)
RN7SL204PGeneProductENSG00000264676 (Ensembl)
RNA5SP122GeneProductENSG00000207186 (Ensembl)
RNPEPL1GeneProductENSG00000142327 (Ensembl)
RNU1-31PGeneProductENSG00000200745 (Ensembl)
RNU6-1051PGeneProductENSG00000202341 (Ensembl)
RNU6-1140PGeneProductENSG00000222449 (Ensembl)
RNU6-1333PGeneProductENSG00000251971 (Ensembl)
RNU6-234PGeneProductENSG00000202099 (Ensembl)
RNU7-127PGeneProductENSG00000238812 (Ensembl)
RPL17P11GeneProductENSG00000233445 (Ensembl)
RPL3P5GeneProductENSG00000231546 (Ensembl)
RPS6ProteinENSG00000137154 (Ensembl)
RRAGAProteinENSG00000155876 (Ensembl)
RRAGBProteinENSG00000083750 (Ensembl)
RRAGCProteinENSG00000116954 (Ensembl)
RRAGDProteinENSG00000025039 (Ensembl)
SCF-like ECS E3 ligase complexComplex
SCF-like ECS E3 ligase complexComplex
SCLYGeneProductENSG00000132330 (Ensembl)
SEPT2GeneProductENSG00000168385 (Ensembl)
SEPTIN12ProteinENSG00000140623 (Ensembl)
SEPTIN2ProteinENSG00000168385 (Ensembl)
SEPTIN4ProteinENSG00000108387 (Ensembl)
SEPTIN6ProteinENSG00000125354 (Ensembl)
SH3BP4GeneProductENSG00000130147 (Ensembl)
SNED1GeneProductENSG00000162804 (Ensembl)
SPASTIC PARAPLEGIA 30, AUTOSOMAL DOMINANT; SPG30610357
SPP2GeneProductENSG00000072080 (Ensembl)
STK25GeneProductENSG00000115694 (Ensembl)
Semaphorin interactionsPathwayWP1907 (WikiPathways)
Sialic acid metabolismPathwayWP3363 (WikiPathways)
Signaling by FGFR2PathwayWP3338 (WikiPathways)
THAP4GeneProductENSG00000176946 (Ensembl)
TMSB10P1GeneProductENSG00000228499 (Ensembl)
TNFProteinENSG00000232810 (Ensembl)
TP53ProteinENSG00000141510 (Ensembl)
TRAF3ProteinENSG00000131323 (Ensembl)
TRAF3IP1GeneProductENSG00000204104 (Ensembl)
TRPM8GeneProductENSG00000144481 (Ensembl)
TWIST2GeneProductENSG00000233608 (Ensembl)
Transferrin receptorQ21112583 (Wikidata)
UBA3-NAE1 E1 complexComplex
UBE2F-SCLYGeneProductENSG00000258984 (Ensembl)
UBE2FGeneProductENSG00000184182 (Ensembl)
UDP-glucuronosyl/UDP-glucosyltransferaseProteinIPR002213 (InterPro)
UGT1A10GeneProductENSG00000242515 (Ensembl)
UGT1A11PGeneProductENSG00000227846 (Ensembl)
UGT1A12PGeneProductENSG00000228949 (Ensembl)
UGT1A13PGeneProductENSG00000234143 (Ensembl)
UGT1A1GeneProductENSG00000242366 (Ensembl)
UGT1A2PGeneProductENSG00000228445 (Ensembl)
UGT1A3GeneProductENSG00000243135 (Ensembl)
UGT1A4GeneProductENSG00000244474 (Ensembl)
UGT1A5GeneProductENSG00000240224 (Ensembl)
UGT1A6GeneProductENSG00000167165 (Ensembl)
UGT1A7GeneProductENSG00000244122 (Ensembl)
UGT1A8GeneProductENSG00000241635 (Ensembl)
UGT1A9GeneProductENSG00000241119 (Ensembl)
USP40GeneProductENSG00000085982 (Ensembl)
acceptor beta-D-glucuronosideMetaboliteCHEBI:132367 (ChEBI)
actin cytoskeleton reorganizationQ14908027 (Wikidata)
actinQ185269 (Wikidata)
aminopeptidase activityQ14864885 (Wikidata)
bleeding Q166019 (Wikidata)
bone remodelingQ952019 (Wikidata)
cholesterolMetaboliteCHEBI:16113 (ChEBI)
clathrin-dependent endocytosisQ14876760 (Wikidata)
collagen VIComplexCPX-1736
cysteine proteaseQ419343 (Wikidata)
dTDPMetaboliteCHEBI:58369 (ChEBI)
dTMPMetaboliteCHEBI:63528 (ChEBI)
erythroblastQ3296909 (Wikidata)
extracellular matrixQ193825 (Wikidata)
galactosylceramideMetaboliteCHEBI:18390 (ChEBI)
glucuronate acceptorMetaboliteCHEBI:132368 (ChEBI)
heparan sulfate groupMetaboliteCHEBI:157750 (ChEBI)
histone deacetylase activity58196 (Rhea)
intercellular bridgeQ14873624 (Wikidata)
kynurenic acidMetaboliteQ642217 (Wikidata)
melanosome transportQ15320928 (Wikidata)
melanosomeQ1065756 (Wikidata)
microtubuleQ189933 (Wikidata)
mitotic spindle assemblyQ14912279 (Wikidata)
nitrateMetaboliteCHEBI:17632 (ChEBI)
oxidative stressQ898814 (Wikidata)
peroxynitriteMetaboliteCHEBI:25941 (ChEBI)
phosphatidylcholineMetaboliteCHEBI:57643 (ChEBI)
phosphatidylserineMetaboliteCHEBI:57262 (ChEBI)
positive regulation of smooth muscle cell proliferationQ14863701 (Wikidata)
protein ubiquitinationQ3547638 (Wikidata)
protein-serine-threonine kinasesQ4857068 (Wikidata)
proteinsMetaboliteCHEBI:36080 (ChEBI)
pyruvateMetaboliteCHEBI:15361 (ChEBI)
rRNA modification in the mitochondrionPathwayWP4099 (WikiPathways)
sensory perception of sound Q14865145 (Wikidata)
sterol metabolic processQ14599656 (Wikidata)
tubulinQ422492 (Wikidata)
vesicle transport along microtubuleQ14882513 (Wikidata)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5224"
Personal tools