Receptor tyrosine kinase (RTK) family (Homo sapiens)

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1Class I: EGFREGFRERBB2ERBB3ERBB4Class II: Insulin RINSRIGFRClass III: PDGFRPDGFRAPDGFRBM-CSFRKITClass IV: VEGFRVEGFR1VEGFR2VEGFR3Class V: FGFRFGFR1FGFR2FGFR3FGFR4Class VI: CCKCCK4Class VII: NGFRTRKATRKBTRKCClass VIII: HGFRMETRONFLT3LClass IX: FGFREPHA1EPHA2EPHA3EPHA4EPHA5EPHA6EPHB1EPHB2EPHB3EPHB4EPHB5EPHB6Class XI: TIETIETEKClass XII: RYKRYKClass XIII: DDRDDR1DDR2Class XIV: RETRETClass XV: ROSROSClass XVI: LTKLTKALKClass XVII: RORROR1ROR2Class XVIII: MUSKMUSKClass XX:METRONMETRONClass XIX: LMRClass X: AXLEGFRERBB2ERBB3AATYK1AATYK2AATYK3


Description

An annotated list of receptor tyrosine kinase (RTK) genes

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Bibliography

  1. Ségaliny AI, Tellez-Gabriel M, Heymann MF, Heymann D; ''Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers.''; J Bone Oncol, 2015 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
129819view22:23, 22 May 2024EweitzModified title
129815view21:53, 22 May 2024EweitzModified title
129808view21:34, 22 May 2024EweitzModified description
129807view21:29, 22 May 2024EweitzAdd literature reference for these 20 classes of RTK
129806view21:20, 22 May 2024EweitzNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AATYK1GeneProduct
AATYK2GeneProduct
AATYK3GeneProduct
ALKGeneProduct
CCK4GeneProduct
DDR1GeneProduct
DDR2GeneProduct
EGFRGeneProduct
EPHA1GeneProduct
EPHA2GeneProduct
EPHA3GeneProduct
EPHA4GeneProduct
EPHA5GeneProduct
EPHA6GeneProduct
EPHB1GeneProduct
EPHB2GeneProduct
EPHB3GeneProduct
EPHB4GeneProduct
EPHB5GeneProduct
EPHB6GeneProduct
ERBB2GeneProduct
ERBB3GeneProduct
ERBB4GeneProduct
FGFR1GeneProduct
FGFR2GeneProduct
FGFR3GeneProduct
FGFR4GeneProduct
FLT3LGeneProduct
IGFRGeneProduct
INSRGeneProduct
KITGeneProduct
LTKGeneProduct
M-CSFRGeneProduct
METGeneProduct
MUSKGeneProduct
PDGFRAGeneProduct
PDGFRBGeneProduct
RETGeneProduct
RONGeneProduct
ROR1GeneProduct
ROR2GeneProduct
ROSGeneProduct
RYKGeneProduct
TEKGeneProduct
TIEGeneProduct
TRKAGeneProduct
TRKBGeneProduct
TRKCGeneProduct
VEGFR1GeneProduct
VEGFR2GeneProduct
VEGFR3GeneProduct

Annotated Interactions

No annotated interactions

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