Regulation of actin cytoskeleton (Danio rerio)

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Actin polymerizationPI3KFocal adhesionassemblyStabilizationof actin+pFilipodiaRTKGFChemotatic factor?Chemotactic factorLamellipodiaGenes in green filled box have been identified in Onchorhynchus mykiss-pFocal complexassemblystress fiberActin polymerizationstress fiberRRAS2Gene ExpressionActomyosinassembly contractionGPCRActin polymerizationSSH2slc9a1WASF1vclcskFocal AdhesionpathwayVAV1msnaACTBvclMAPK Signalingpathwayactn1CFL1fn1f2LOC568935pip4k2aaTMSB4Ymapk14bPIP3ptk2.1fgd1pip4k2aasos2MAP2K2asi:dkey-74f15.3wasbPIP2myl1PAK2gna13appp1r12aACTG1rock2af2rFocal AdhesionpathwayDIAP1AcetylcholineARHGEF1ACTBINS2ABI2iqgap1cdc42lARPC5vil1lPFN1Apc2mylkbapcmyh9GRLF1ARHGEF7PIP2BAIAP2gsnaDIAP3ACTG1PAK2dock1crkSOS1zgc:153713itga4ARPC5ACTG1BradykininINS1VIL2Adherens junctionpathwaygna12raf1aGNG12ROCK1msnbPFN1bcar1ACTBlimk1WASF2ENAHcfl2zgc:114164BAIAP2LOC558288Poly(IC)itga5iqgap2iqgap3actn4


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History

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CompareRevisionActionTimeUserComment
134154view21:31, 15 July 2024EweitzModified title
130622view05:11, 29 May 2024Khansperswork in progress
130621view05:02, 29 May 2024Khanspersconnected interactions, converted some to graphical lines
126435view10:14, 28 April 2023EgonwLicense is CCZero
123554view17:57, 3 August 2022EgonwMade three pathways clickable
118076view10:43, 24 May 2021EweitzModified title
102807view14:40, 24 January 2019DeSlOntology Term : 'regulatory pathway' added !
98713view11:55, 1 October 2018Scm3New pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABI2GeneProduct561894 (Entrez Gene)
ACTBGeneProduct
ACTG1GeneProduct
ARHGEF1GeneProduct
ARHGEF7GeneProduct558288 (Entrez Gene)
ARPC5GeneProduct
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct
BradykininMetabolite58-82-2 (CAS)
CFL1GeneProduct
DIAP1GeneProduct
DIAP3GeneProduct
ENAHGeneProduct
Focal Adhesion pathwayPathwayWP306 (WikiPathways)
GNG12GeneProduct
GRLF1GeneProduct
INS1GeneProduct
INS2GeneProduct
LOC558288GeneProduct558288 (Entrez Gene)
LOC568935GeneProduct568935 (Entrez Gene)
MAP2K2aGeneProduct
MAPK Signaling pathwayPathwayWP382 (WikiPathways)
PAK2GeneProduct
PAK2GeneProduct327204 (Entrez Gene)
PFN1GeneProduct
PIP2MetaboliteC04637 (KEGG Compound)
PIP3MetaboliteC05981 (KEGG Compound)
Poly(IC)MetaboliteC00338 (KEGG Compound)
ROCK1GeneProduct
SOS1GeneProduct
SSH2GeneProduct
TMSB4YGeneProduct
VAV1GeneProduct
VIL2GeneProduct
WASF1GeneProduct
WASF2GeneProduct
actn1GeneProduct560400 (Entrez Gene)
actn4GeneProductENSDARG00000099786 (Ensembl)
apcGeneProduct386762 (Entrez Gene)
bcar1GeneProduct568309 (Entrez Gene)
cdc42lGeneProduct793158 (Entrez Gene)
cfl2GeneProduct403001 (Entrez Gene)
crkGeneProduct445234 (Entrez Gene)
cskGeneProduct556454 (Entrez Gene)
dock1GeneProduct572187 (Entrez Gene)
f2GeneProduct325881 (Entrez Gene)
f2rGeneProduct558477 (Entrez Gene)
fgd1GeneProduct560305 (Entrez Gene)
fn1GeneProduct100005469 (Entrez Gene)
gna12GeneProduct503589 (Entrez Gene)
gna13aGeneProduct326825 (Entrez Gene)
gsnaGeneProduct321099 (Entrez Gene)
iqgap1GeneProduct100002928 (Entrez Gene)
iqgap2GeneProductENSDARG00000060010 (Ensembl)
iqgap3GeneProductENSDARG00000098650 (Ensembl)
itga4GeneProduct570868 (Entrez Gene)
itga5GeneProduct570868 (Entrez Gene)
limk1GeneProduct735292 (Entrez Gene)
mapk14bGeneProduct565830 (Entrez Gene)
msnaGeneProduct286739 (Entrez Gene)
msnbGeneProduct553434 (Entrez Gene)
myh9GeneProduct555454 (Entrez Gene)
myl1GeneProduct336165 (Entrez Gene)
mylkbGeneProduct492576 (Entrez Gene)
pip4k2aaGeneProduct560360 (Entrez Gene)
ppp1r12aGeneProduct445393 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
raf1aGeneProduct557109 (Entrez Gene)
rock2aGeneProduct317747 (Entrez Gene)
si:dkey-74f15.3GeneProduct559017 (Entrez Gene)
slc9a1GeneProduct795135 (Entrez Gene)
sos2GeneProduct561670 (Entrez Gene)
vclGeneProduct552980 (Entrez Gene)
vil1lGeneProduct393207 (Entrez Gene)
wasbGeneProduct335158 (Entrez Gene)
zgc:114164GeneProduct574004 (Entrez Gene)
zgc:153713GeneProduct751630 (Entrez Gene)

Annotated Interactions

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