ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (Homo sapiens)

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1nucleusAutocrine signaling loopSTAT3 target genesCancer stem cellsEpithelial mesenchymal transitionMIR21NFKB1STAT3lncSox4IL6STRELAIL6JAK1lncRNA-ATBIL11RAIL11IL6RJAK2JAK3JAK1JAK2JAK3IL6IL11STAT3ZEB1SOX4MIR200AMIR200BMIR200CMIR21SOX4UCA1DILCIL6


Description

This pathway describes the influence of ncRNAs on the STAT3 pathway in hepatocellular carcinoma. The model is based on Fig 4 in Klingenberg et al.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Klingenberg M, Matsuda A, Diederichs S, Patel T; ''Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets.''; J Hepatol, 2017 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134811view11:06, 27 July 2024EweitzRefine layering
134810view10:56, 27 July 2024EweitzEconomize layout
134809view10:53, 27 July 2024EweitzOntology Term : 'stem cell' added !
134808view10:49, 27 July 2024EweitzMitigate graphical discrepancy between PathVisio and Kaavio / Pvjs
134807view10:49, 27 July 2024EweitzStandardize case, mitigate graphical discrepancy between PathVisio and Kaavio / Pvjs
108190view10:55, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
108189view10:55, 29 November 2019FehrhartOntology Term : 'hepatocyte' added !
105489view05:44, 8 August 2019KhanspersModified description
105473view05:20, 8 August 2019KhanspersModified description
98466view19:12, 7 September 2018KhanspersOntology Term : 'altered Jak-Stat signaling pathway' added !
98465view19:12, 7 September 2018KhanspersOntology Term : 'hepatocellular carcinoma' added !
98464view19:11, 7 September 2018KhanspersModified description
98463view19:09, 7 September 2018KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
DILCRna
IL11GeneProductENSG00000095752 (Ensembl)
IL11RAGeneProductENSG00000137070 (Ensembl)
IL6GeneProductENSG00000136244 (Ensembl)
IL6RGeneProductENSG00000160712 (Ensembl)
IL6STGeneProductENSG00000134352 (Ensembl)
JAK1GeneProductENSG00000162434 (Ensembl)
JAK2GeneProductENSG00000096968 (Ensembl)
JAK3GeneProductENSG00000105639 (Ensembl)
MIR200AGeneProductENSG00000207607 (Ensembl)
MIR200BGeneProductENSG00000207730 (Ensembl)
MIR200CGeneProductENSG00000207713 (Ensembl)
MIR21GeneProductENSG00000284190 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
RELAGeneProductENSG00000173039 (Ensembl)
SOX4GeneProductENSG00000124766 (Ensembl)
STAT3GeneProductENSG00000168610 (Ensembl)
UCA1GeneProductENSG00000214049 (Ensembl)
ZEB1GeneProductENSG00000148516 (Ensembl)
lncRNA-ATBRna
lncSox4Rna

Annotated Interactions

No annotated interactions

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