Age-related macular degeneration (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none mTORC1AMPKPARP2SIRT1PPARGC1ARPTORMTORRPTORMLST8RPS6KB1MAPK3PMAIP1MDH1Name: Age-related macular degenerationOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Curated.pngReview changes for Approved

Ontology Terms

 

Bibliography

  1. Zhang M, Jiang N, Chu Y, Postnikova O, Varghese R, Horvath A, Cheema AK, Golestaneh N; ''Dysregulated metabolic pathways in age-related macular degeneration.''; Sci Rep, 2020 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
138229
Approved
view01:21, 26 March 2025EweitzFix truncated text
138219view12:23, 25 March 2025EweitzConvey up- vs. down-regulation in disease via font style, refine legend
138218view12:03, 25 March 2025EweitzRefine interactions, start legend
138217view03:59, 25 March 2025EweitzOntology Term : 'age related macular degeneration' added !
138216view03:59, 25 March 2025EweitzOntology Term : 'retinal pigment epithelial cell' added !
138215view03:59, 25 March 2025EweitzModified description
138214view03:57, 25 March 2025EweitzModified description
138213view03:56, 25 March 2025EweitzModified description
138212view03:51, 25 March 2025EweitzAdd literature reference
138211view03:49, 25 March 2025EweitzLabel cell type
138210view03:42, 25 March 2025EweitzAdd more interactions
138209view03:31, 25 March 2025EweitzConvert unknowns to pathways, add cell compartments
138208view03:20, 25 March 2025EweitzUpgrade nodes, identify pathways
138207view03:15, 25 March 2025EweitzIdentify metabolites
138206view02:56, 25 March 2025EweitzEconomize layout
138205view02:53, 25 March 2025EweitzAdd interactions
138204view02:25, 25 March 2025EweitzAdd process, metabolite nodes
138203view02:09, 25 March 2025EweitzArrange nodes
138202view21:46, 24 March 2025EweitzAdd AMPK complex, with explicit genes
138201view21:44, 24 March 2025EweitzNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
MAPK3GeneProduct
MDH1GeneProduct
MLST8GeneProduct
MTORGeneProduct
PARP2GeneProduct
PMAIP1GeneProduct
PPARGC1AGeneProduct"PGC1a" in source
RPS6KB1GeneProduct
RPTORGeneProduct
SIRT1GeneProduct

Annotated Interactions

No annotated interactions

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