Age-related macular degeneration (Homo sapiens)

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Revision as of 03:15, 25 March 2025 by Eweitz (Talk | contribs)
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Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Zhang M, Jiang N, Chu Y, Postnikova O, Varghese R, Horvath A, Cheema AK, Golestaneh N; ''Dysregulated metabolic pathways in age-related macular degeneration.''; Sci Rep, 2020 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
140860view00:13, 30 October 2025EweitzClear deprecated metadata rendering
138229view01:21, 26 March 2025EweitzFix truncated text
138219view12:23, 25 March 2025EweitzConvey up- vs. down-regulation in disease via font style, refine legend
138218view12:03, 25 March 2025EweitzRefine interactions, start legend
138217view03:59, 25 March 2025EweitzOntology Term : 'age related macular degeneration' added !
138216view03:59, 25 March 2025EweitzOntology Term : 'retinal pigment epithelial cell' added !
138215view03:59, 25 March 2025EweitzModified description
138214view03:57, 25 March 2025EweitzModified description
138213view03:56, 25 March 2025EweitzModified description
138212view03:51, 25 March 2025EweitzAdd literature reference
138211view03:49, 25 March 2025EweitzLabel cell type
138210view03:42, 25 March 2025EweitzAdd more interactions
138209view03:31, 25 March 2025EweitzConvert unknowns to pathways, add cell compartments
138208view03:20, 25 March 2025EweitzUpgrade nodes, identify pathways
138207view03:15, 25 March 2025EweitzIdentify metabolites
138206view02:56, 25 March 2025EweitzEconomize layout
138205view02:53, 25 March 2025EweitzAdd interactions
138204view02:25, 25 March 2025EweitzAdd process, metabolite nodes
138203view02:09, 25 March 2025EweitzArrange nodes
138202view21:46, 24 March 2025EweitzAdd AMPK complex, with explicit genes
138201view21:44, 24 March 2025EweitzNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Apoptosis
Autophagy
Glycolysis
Lipid degeneration
MAPK3GeneProductENSG00000102882 (Ensembl)
MDH1GeneProductENSG00000014641 (Ensembl)
MLST8GeneProductENSG00000167965 (Ensembl)
MTORGeneProductENSG00000198793 (Ensembl)
MalateMetaboliteCHEBI:25115 (ChEBI)
Mitochondrial damage
Mitochondrion

organization

and biogenesis
NAD+MetaboliteCHEBI:15846 (ChEBI)
OxaloacetateMetaboliteCHEBI:16452 (ChEBI)
PARP2GeneProductENSG00000129484 (Ensembl)
PMAIP1GeneProductENSG00000141682 (Ensembl)
PPARGC1AGeneProductENSG00000109819 (Ensembl) "PGC1a" in source
PRKAA1GeneProductENSG00000132356 (Ensembl)
PRKAA2GeneProductENSG00000162409 (Ensembl)
PRKAB1GeneProductENSG00000111725 (Ensembl)
PRKAB2GeneProductENSG00000131791 (Ensembl)
PRKAG1GeneProductENSG00000181929 (Ensembl)
PRKAG2GeneProductENSG00000106617 (Ensembl)
PRKAG3GeneProductENSG00000115592 (Ensembl)
RPS6KB1GeneProductENSG00000108443 (Ensembl)
RPTORGeneProductENSG00000141564 (Ensembl)
Ribosome

biogenesis and

assembly
SIRT1GeneProductENSG00000096717 (Ensembl)

Annotated Interactions

No annotated interactions

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