Visual cycle (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none RDH12RBP3LRATRDH10RDH5RLBP1RDH8RBP1RPE65RDH11OPN1SWRHOOPN1MWOPN1LWName: Retinoid cycle metabolic pathwayOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Curated.pngReview changes for Approved

Ontology Terms

 

Bibliography

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  1. Kiser PD, Golczak M, Maeda A, Palczewski K; ''Key enzymes of the retinoid (visual) cycle in vertebrate retina.''; Biochim Biophys Acta, 2012 PubMed Europe PMC Scholia
  2. Wang JS, Kefalov VJ; ''The cone-specific visual cycle.''; Prog Retin Eye Res, 2011 PubMed Europe PMC Scholia
  3. Haeseleer F, Jang GF, Imanishi Y, Driessen CAGG, Matsumura M, Nelson PS, Palczewski K; ''Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina.''; J Biol Chem, 2002 PubMed Europe PMC Scholia
  4. Pollock NL, Callaghan R; ''The lipid translocase, ABCA4: seeing is believing.''; FEBS J, 2011 PubMed Europe PMC Scholia
  5. Persson B, Kallberg Y, Oppermann U, Jörnvall H; ''Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs).''; Chem Biol Interact, 2003 PubMed Europe PMC Scholia
  6. von Lintig J; ''Metabolism of carotenoids and retinoids related to vision.''; J Biol Chem, 2012 PubMed Europe PMC Scholia
  7. Kiser PD, Palczewski K; ''Membrane-binding and enzymatic properties of RPE65.''; Prog Retin Eye Res, 2010 PubMed Europe PMC Scholia
  8. Bray JE, Marsden BD, Oppermann U; ''The human short-chain dehydrogenase/reductase (SDR) superfamily: a bioinformatics summary.''; Chem Biol Interact, 2009 PubMed Europe PMC Scholia
  9. von Lintig J, Kiser PD, Golczak M, Palczewski K; ''The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision.''; Trends Biochem Sci, 2010 PubMed Europe PMC Scholia
  10. Takahashi Y, Moiseyev G, Chen Y, Ma JX; ''The roles of three palmitoylation sites of RPE65 in its membrane association and isomerohydrolase activity.''; Invest Ophthalmol Vis Sci, 2006 PubMed Europe PMC Scholia
  11. Jörnvall H, Hedlund J, Bergman T, Oppermann U, Persson B; ''Superfamilies SDR and MDR: from early ancestry to present forms. Emergence of three lines, a Zn-metalloenzyme, and distinct variabilities.''; Biochem Biophys Res Commun, 2010 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
138466view20:02, 11 April 2025EgonwModified description
138465view16:29, 11 April 2025EgonwModified description
138416view18:53, 6 April 2025EweitzRefine label
138415view18:48, 6 April 2025EweitzEconomize layout
138414view18:35, 6 April 2025EweitzEconomize layout
138412view13:47, 6 April 2025EweitzOntology Term : 'retinal rod cell' added !
138411view13:47, 6 April 2025EweitzOntology Term : 'compound eye cone cell' added !
138410view13:47, 6 April 2025EweitzOntology Term : 'retinal pigment epithelial cell' added !
138409view13:46, 6 April 2025EweitzOntology Term : 'retinoid cycle metabolic pathway' added !
138408view13:45, 6 April 2025EweitzModified description
138407view13:44, 6 April 2025EweitzModified description
138406view13:40, 6 April 2025EweitzAdd literature references
138405view13:34, 6 April 2025EweitzEconomize layout
138404view13:32, 6 April 2025EweitzAdd cells
138403view13:21, 6 April 2025EweitzModified title
138402view13:18, 6 April 2025EweitzAdd interactions, arrange
138401view22:51, 5 April 2025EweitzArrange nodes
138400view22:24, 5 April 2025EweitzAdd, identify metabolites
138399view21:58, 5 April 2025EweitzArrange genes
138398view21:50, 5 April 2025EweitzAdd identifiers to genes
138397view21:40, 5 April 2025EweitzNew pathway

External references

DataNodes

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Name  ↓Type  ↓Database reference  ↓Comment  ↓
LRATGeneProduct
OPN1LWGeneProduct
OPN1MWGeneProduct
OPN1SWGeneProduct
RBP1GeneProduct
RBP3GeneProduct
RDH10GeneProduct
RDH11GeneProduct
RDH12GeneProduct
RDH5GeneProduct
RDH8GeneProduct
RHOGeneProduct
RLBP1GeneProduct
RPE65GeneProduct

Annotated Interactions

No annotated interactions

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