Prostaglandin synthesis and regulation (Canis familiaris)

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Gq signalingpathwayCytoplasmCell MembranePhospholipidsInactive MetabolitesprolactinreleasePG SynthasesCortisonePGF2aPGI2PTGISANXA5PTGS1PTGDRPTGS2CalciumPTGIRPRLANXA2ANXA3EDNRBANXA1PGE2PTGER1S100A10TBXAS1EDNRAPTGER4ProgesteroneCalciumHPGDSCGB1A1Prostaglandin H2PTGFRS100A6ANXA6CortisolEDN1Arachidonic AcidPTGER2HSD11B2PTGDSPLA2G4AANXA8ANXA4PGF2aPTGER3CortisolTXA2LOC478365HSD11B1


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 80% conversion rate.

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Quality Tags

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Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
118056view10:36, 24 May 2021EweitzModified title
106037view11:56, 16 August 2019MaintBotHMDB identifier normalization
87601view08:53, 25 July 2016LindarieswijkOntology Term : 'prostaglandin biosynthetic pathway' added !
87600view08:53, 25 July 2016LindarieswijkOntology Term : 'prostaglandin signaling pathway' added !
71459view19:17, 17 October 2013MaintBotAutomated update of data sources
68524view22:08, 5 July 2013MaintBotUpdated to 2013 gpml schema
40678view21:49, 1 March 2011MaintBotRemoved redundant pathway information and comments
33968view18:27, 9 December 2009MaintBotAutomatic update of empty xrefs
32549view13:05, 17 August 2009MaintBotFixed text labels
32231view12:49, 15 August 2009MaintBotFixed text labels
31737view11:59, 14 August 2009MaintBotFixed group labels
31247view19:50, 13 August 2009MaintBotFixed text labels
30680view22:43, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ANXA1GeneProduct476322 (Entrez Gene)
ANXA2GeneProduct403435 (Entrez Gene)
ANXA3GeneProduct478447 (Entrez Gene)
ANXA4GeneProduct606756 (Entrez Gene)
ANXA5GeneProduct476094 (Entrez Gene)
ANXA6GeneProduct479325 (Entrez Gene)
ANXA8GeneProduct
Arachidonic AcidGeneProduct
CalciumMetaboliteHMDB00464 (HMDB)
CortisolGeneProduct
EDN1GeneProduct403424 (Entrez Gene) PMID: 1474344
EDNRAGeneProduct450187 (Entrez Gene)
EDNRBGeneProduct403862 (Entrez Gene)
HPGDGeneProduct486073 (Entrez Gene)
HSD11B1GeneProduct449023 (Entrez Gene)
HSD11B2GeneProduct489758 (Entrez Gene)
LOC478365GeneProduct478365 (Entrez Gene)
PGE2MetaboliteHMDB03175 (HMDB)
PGF2aMetaboliteHMDB01139 (HMDB)
PGI2MetaboliteHMDB01335 (HMDB)
PLA2G4AGeneProduct480048 (Entrez Gene)
PRLGeneProduct488241 (Entrez Gene)
PTGDRGeneProduct610845 (Entrez Gene)
PTGDSGeneProduct403740 (Entrez Gene)
PTGER1GeneProduct610774 (Entrez Gene)
PTGER2GeneProduct403797 (Entrez Gene)
PTGER3GeneProduct
PTGER4GeneProduct403589 (Entrez Gene)
PTGFRGeneProduct479981 (Entrez Gene)
PTGIRGeneProduct484429 (Entrez Gene)
PTGISGeneProduct485919 (Entrez Gene)
PTGS1GeneProduct403544 (Entrez Gene)
PTGS2GeneProduct442942 (Entrez Gene)
ProgesteroneGeneProduct
Prostaglandin H2GeneProduct
S100A10GeneProduct475851 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
S100A6GeneProduct480143 (Entrez Gene)
SCGB1A1GeneProduct476060 (Entrez Gene) PMID: 7615804, PMID: 3292559
TBXAS1GeneProduct482771 (Entrez Gene)
TXA2MetaboliteHMDB01452 (HMDB)

Annotated Interactions

No annotated interactions
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