Metapathway biotransformation (Mus musculus)
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Acetylation
Glutathione transferases
Electrophiles
Sulfotransferases
Glutathione reductase
Glutathione synthetase
Glutathione peroxidases
N-acetyltransferases
Sulfation
Amino acid acyl transferases
Glutathione conjugation
Glucuronosyltransferases
Glucuronidation
Methylation
Methyltransferases
Epoxide hydrolases
Aldo-keto reductases
Flavin monooxygenases
Reduction
Hydrolysis
Nucleophiles
Cytochrome P450
Oxidation
Amino acid conjugation
Ugt1a10
Kcnab1
CYP4F12
Hs2st1
CYP2A6
Ugt1a5
Nat5
GSTA3
Cyp27b1
CYP4F2
AKR1C1
Hs3st1
Cyp24a1
Substrate-Aa
Nat13
Hs6st3
Cyp20a1
Substrate-Ac
Cyp2f2
SULT2A1
Chst3
Substrate-SH
CYP2A13
Chst1
UGT1A10
Cyp7a1
Mgst3
Akr1b3
GSTP1
Gpx5
Gpx4
Chst11
UGT1A9
Gstt2
Cyp2e1
Gstcd
Methyltransferase
Flavin monooxygenase
Gstt2
Kcnab3
Fmo1
Hs3st5
Akr1d1
AC161058.2-1
CYP2J2
Cyp2u1
Ugt1a2
AC122521.4
Chst4
Substrate-OH
UGT2B17
CYP2D6
Hs3st2
Hs6st1
Cyp4f18
NAT1
CYP4Z1
Cyp26a1
CYP2C8
Substrate-O-R
Ephx1
Ndst4
Gpx3
Sult1b1
GSTA4
Substrate-CH3
GSTA1
Gal3st1
Substrate=O
Nat10
Hs3st6
Nat8l
Chst8
Chst5
Sult4a1
Nat6
Cyp27a1
GSTM1
UGT2B7
Sult2b1
Substrate-Gl
Ndst1
Chst14
Fmo5
Chst2
GLYATL1
Mgst1
Chst5
Kcnab2
Sult1e1
Sult1a1
Glyat
Cyp4x1
CYP2C9
Cyp19a1
N-acetyltransferase
CYP27C1
Fmo2
GSTA2
Cyp2s1
Nnmt
UGT2B28
Substrate-SG
Gstt1
Hnmt
Ugt2a2
Gpx2
Sult1a1
Gsto2
GAL3ST2
UGT2B11
Gsr
Gstz1
CYP4F8
CYP11B1
Nat14
Gpx1
CYP450
Substrate-NH2
Amino acid acyltransferase
Cyp21a1
Glucuronosyltransferase
Gstm7
Ndst3
Cyp1a2
GLYATL2
AKR1C3
Akr7a5
SULT1C3
Comt1
Chst7
Sult1c2
Baat
Gsto1
Cyp4b1
Sulfotransferase
Chst9
UGT2A2
GSTM5
HS3ST3A1
Gal3st3
Mgst2
CYP11B2
UGT1A5
Gal3st4
Gss
Cyp26b1
CYP2C19
Chst10
Cyp39a1
UGT1A6
Cyp17a1
Hs3st4
Cyp11a1
Cyp46a1
CYP3A7
SULT1C2
Gstk1
CYP2C18
Aldo-keto reductase
GSTM4
CYP3A5
Hs6st2
Cyp4f39
Gstm5
Xenobiotic substrate
Ugt2a3
UGT2B4
HS3ST3B1
Cyp2r1
AKR1C4
CYP3A4
Cyp8b1
Fmo3
Sult1a1
AKR7A3
UGT1A7
Cyp1b1
Cyp1a1
Nat9
Cyp7b1
Nat12
Ugt1a1
Tpmt
Substrate-SO3H
NAT8
Chst12
AKR1B10
Ephx2
CYP3A43
Ndst2
SULT1C4
CYP2A7
GSTA5
CYP4F11
Akr1a4
Cyp51
AKR1C2
NAT2
CYP2B6
Fmo4
Sult1a1
Cyp4v3
Cyp26c1
AC154274.1-1
Glutathione transferase
UGT2B15
AC140307.3-1
Inmt
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 64% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
94721
view
14:08, 5 October 2017
Egonw
Converted two complexes (which they are not) to groups.
94720
view
14:04, 5 October 2017
Egonw
Mim-typed interactions.
69747
view
09:37, 11 July 2013
Egonw
Added ChEBI identifiers for a few compound classes.
69160
view
18:19, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67456
view
11:04, 26 June 2013
Ddigles
Ontology Term : 'cellular detoxification pathway' added !
59060
view
21:01, 21 February 2013
MaintBot
Updated Ensembl and UniProt data source
58513
view
19:13, 14 February 2013
MaintBot
Modified title
41349
view
00:26, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34408
view
23:07, 9 December 2009
MaintBot
Automatic update of empty xrefs
33190
view
18:06, 5 November 2009
Khanspers
Modified categories
32293
view
13:12, 15 August 2009
MaintBot
Fixed text labels
31856
view
12:33, 14 August 2009
MaintBot
Fixed group labels
31321
view
20:17, 13 August 2009
MaintBot
Fixed text labels
30847
view
00:06, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AC122521.4
GeneProduct
ENSMUSG00000056643 (Ensembl Mouse)
AC140307.3-1
GeneProduct
ENSMUSG00000024764 (Ensembl Mouse)
AC154274.1-1
GeneProduct
ENSMUSG00000038045 (Ensembl Mouse)
AC161058.2-1
GeneProduct
ENSMUSG00000029541 (Ensembl Mouse)
AKR1B10
GeneProduct
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
AKR1C4
GeneProduct
AKR7A3
GeneProduct
Akr1a4
GeneProduct
ENSMUSG00000028692 (Ensembl Mouse)
Akr1b3
GeneProduct
ENSMUSG00000001642 (Ensembl Mouse)
Akr1d1
GeneProduct
ENSMUSG00000038641 (Ensembl Mouse)
Akr7a5
GeneProduct
ENSMUSG00000028743 (Ensembl Mouse)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
Baat
GeneProduct
ENSMUSG00000039653 (Ensembl Mouse)
CYP11B1
GeneProduct
CYP11B2
GeneProduct
CYP27C1
GeneProduct
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2B6
GeneProduct
CYP2C18
GeneProduct
CYP2C19
GeneProduct
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
CYP2J2
GeneProduct
CYP3A4
GeneProduct
CYP3A43
GeneProduct
CYP3A5
GeneProduct
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F2
GeneProduct
CYP4F8
GeneProduct
CYP4Z1
GeneProduct
Chst10
GeneProduct
ENSMUSG00000026080 (Ensembl Mouse)
Chst11
GeneProduct
ENSMUSG00000034612 (Ensembl Mouse)
Chst12
GeneProduct
ENSMUSG00000036599 (Ensembl Mouse)
Chst14
GeneProduct
72136 (Entrez Gene)
Chst1
GeneProduct
ENSMUSG00000027221 (Ensembl Mouse)
Chst2
GeneProduct
ENSMUSG00000033350 (Ensembl Mouse)
Chst3
GeneProduct
ENSMUSG00000057337 (Ensembl Mouse)
Chst4
GeneProduct
ENSMUSG00000035930 (Ensembl Mouse)
Chst5
GeneProduct
ENSMUSG00000031952 (Ensembl Mouse)
Chst7
GeneProduct
ENSMUSG00000037347 (Ensembl Mouse)
Chst8
GeneProduct
ENSMUSG00000060402 (Ensembl Mouse)
Chst9
GeneProduct
71367 (Entrez Gene)
Comt1
GeneProduct
ENSMUSG00000000326 (Ensembl Mouse)
Cyp11a1
GeneProduct
ENSMUSG00000032323 (Ensembl Mouse)
Cyp17a1
GeneProduct
ENSMUSG00000003555 (Ensembl Mouse)
Cyp19a1
GeneProduct
ENSMUSG00000032274 (Ensembl Mouse)
Cyp1a1
GeneProduct
ENSMUSG00000032315 (Ensembl Mouse)
Cyp1a2
GeneProduct
ENSMUSG00000032310 (Ensembl Mouse)
Cyp1b1
GeneProduct
ENSMUSG00000024087 (Ensembl Mouse)
Cyp20a1
GeneProduct
ENSMUSG00000049439 (Ensembl Mouse)
Cyp21a1
GeneProduct
13079 (Entrez Gene)
Cyp24a1
GeneProduct
ENSMUSG00000038567 (Ensembl Mouse)
Cyp26a1
GeneProduct
ENSMUSG00000024987 (Ensembl Mouse)
Cyp26b1
GeneProduct
ENSMUSG00000063415 (Ensembl Mouse)
Cyp26c1
GeneProduct
ENSMUSG00000062432 (Ensembl Mouse)
Cyp27a1
GeneProduct
ENSMUSG00000026170 (Ensembl Mouse)
Cyp27b1
GeneProduct
ENSMUSG00000006724 (Ensembl Mouse)
Cyp2e1
GeneProduct
ENSMUSG00000025479 (Ensembl Mouse)
Cyp2f2
GeneProduct
ENSMUSG00000052974 (Ensembl Mouse)
Cyp2r1
GeneProduct
ENSMUSG00000030670 (Ensembl Mouse)
Cyp2s1
GeneProduct
ENSMUSG00000040703 (Ensembl Mouse)
Cyp2u1
GeneProduct
ENSMUSG00000027983 (Ensembl Mouse)
Cyp39a1
GeneProduct
ENSMUSG00000023963 (Ensembl Mouse)
Cyp46a1
GeneProduct
ENSMUSG00000021259 (Ensembl Mouse)
Cyp4b1
GeneProduct
ENSMUSG00000028713 (Ensembl Mouse)
Cyp4f18
GeneProduct
ENSMUSG00000003484 (Ensembl Mouse)
Cyp4f39
GeneProduct
ENSMUSG00000061126 (Ensembl Mouse)
Cyp4v3
GeneProduct
ENSMUSG00000079057 (Ensembl Mouse)
Cyp4x1
GeneProduct
ENSMUSG00000047155 (Ensembl Mouse)
Cyp51
GeneProduct
ENSMUSG00000001467 (Ensembl Mouse)
Cyp7a1
GeneProduct
ENSMUSG00000028240 (Ensembl Mouse)
Cyp7b1
GeneProduct
ENSMUSG00000039519 (Ensembl Mouse)
Cyp8b1
GeneProduct
ENSMUSG00000050445 (Ensembl Mouse)
Ephx1
GeneProduct
ENSMUSG00000038776 (Ensembl Mouse)
Ephx2
GeneProduct
ENSMUSG00000022040 (Ensembl Mouse)
Flavin monooxygenase
GeneProduct
Fmo1
GeneProduct
ENSMUSG00000040181 (Ensembl Mouse)
Fmo2
GeneProduct
ENSMUSG00000040170 (Ensembl Mouse)
Fmo3
GeneProduct
ENSMUSG00000026691 (Ensembl Mouse)
Fmo4
GeneProduct
ENSMUSG00000026692 (Ensembl Mouse)
Fmo5
GeneProduct
ENSMUSG00000028088 (Ensembl Mouse)
GAL3ST2
GeneProduct
GLYATL1
GeneProduct
GLYATL2
GeneProduct
GSTA1
GeneProduct
GSTA2
GeneProduct
GSTA3
GeneProduct
GSTA4
GeneProduct
GSTA5
GeneProduct
GSTM1
GeneProduct
GSTM4
GeneProduct
GSTM5
GeneProduct
GSTP1
GeneProduct
Gal3st1
GeneProduct
ENSMUSG00000049721 (Ensembl Mouse)
Gal3st3
GeneProduct
ENSMUSG00000047658 (Ensembl Mouse)
Gal3st4
GeneProduct
ENSMUSG00000075593 (Ensembl Mouse)
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
Glyat
GeneProduct
ENSMUSG00000063683 (Ensembl Mouse)
Gpx1
GeneProduct
ENSMUSG00000063856 (Ensembl Mouse)
Gpx2
GeneProduct
ENSMUSG00000042808 (Ensembl Mouse)
Gpx3
GeneProduct
ENSMUSG00000018339 (Ensembl Mouse)
Gpx4
GeneProduct
ENSMUSG00000075706 (Ensembl Mouse)
Gpx5
GeneProduct
ENSMUSG00000004344 (Ensembl Mouse)
Gsr
GeneProduct
ENSMUSG00000031584 (Ensembl Mouse)
Gss
GeneProduct
ENSMUSG00000027610 (Ensembl Mouse)
Gstcd
GeneProduct
ENSMUSG00000028018 (Ensembl Mouse)
Gstk1
GeneProduct
ENSMUSG00000029864 (Ensembl Mouse)
Gstm5
GeneProduct
ENSMUSG00000004032 (Ensembl Mouse)
Gstm7
GeneProduct
ENSMUSG00000004035 (Ensembl Mouse)
Gsto1
GeneProduct
ENSMUSG00000025068 (Ensembl Mouse)
Gsto2
GeneProduct
ENSMUSG00000025069 (Ensembl Mouse)
Gstt1
GeneProduct
ENSMUSG00000001663 (Ensembl Mouse)
Gstt2
GeneProduct
ENSMUSG00000033318 (Ensembl Mouse)
Gstz1
GeneProduct
ENSMUSG00000021033 (Ensembl Mouse)
HS3ST3A1
GeneProduct
HS3ST3B1
GeneProduct
Hnmt
GeneProduct
ENSMUSG00000026986 (Ensembl Mouse)
Hs2st1
GeneProduct
ENSMUSG00000040151 (Ensembl Mouse)
Hs3st1
GeneProduct
ENSMUSG00000051022 (Ensembl Mouse)
Hs3st2
GeneProduct
ENSMUSG00000046321 (Ensembl Mouse)
Hs3st4
GeneProduct
ENSMUSG00000078591 (Ensembl Mouse)
Hs3st5
GeneProduct
ENSMUSG00000044499 (Ensembl Mouse)
Hs3st6
GeneProduct
ENSMUSG00000039628 (Ensembl Mouse)
Hs6st1
GeneProduct
ENSMUSG00000045216 (Ensembl Mouse)
Hs6st2
GeneProduct
ENSMUSG00000062184 (Ensembl Mouse)
Hs6st3
GeneProduct
ENSMUSG00000053465 (Ensembl Mouse)
Inmt
GeneProduct
ENSMUSG00000003477 (Ensembl Mouse)
Kcnab1
GeneProduct
ENSMUSG00000027827 (Ensembl Mouse)
Kcnab2
GeneProduct
ENSMUSG00000028931 (Ensembl Mouse)
Kcnab3
GeneProduct
ENSMUSG00000018470 (Ensembl Mouse)
Methyltransferase
GeneProduct
Mgst1
GeneProduct
ENSMUSG00000008540 (Ensembl Mouse)
Mgst2
GeneProduct
ENSMUSG00000074604 (Ensembl Mouse)
Mgst3
GeneProduct
ENSMUSG00000026688 (Ensembl Mouse)
N-acetyltransferase
GeneProduct
NAT1
GeneProduct
NAT2
GeneProduct
NAT8
GeneProduct
Nat10
GeneProduct
ENSMUSG00000027185 (Ensembl Mouse)
Nat12
GeneProduct
ENSMUSG00000036282 (Ensembl Mouse)
Nat13
GeneProduct
ENSMUSG00000022698 (Ensembl Mouse)
Nat14
GeneProduct
ENSMUSG00000035285 (Ensembl Mouse)
Nat5
GeneProduct
ENSMUSG00000002728 (Ensembl Mouse)
Nat6
GeneProduct
ENSMUSG00000079334 (Ensembl Mouse)
Nat8l
GeneProduct
ENSMUSG00000048142 (Ensembl Mouse)
Nat9
GeneProduct
ENSMUSG00000015542 (Ensembl Mouse)
Ndst1
GeneProduct
ENSMUSG00000054008 (Ensembl Mouse)
Ndst2
GeneProduct
ENSMUSG00000039308 (Ensembl Mouse)
Ndst3
GeneProduct
ENSMUSG00000027977 (Ensembl Mouse)
Ndst4
GeneProduct
ENSMUSG00000027971 (Ensembl Mouse)
Nnmt
GeneProduct
ENSMUSG00000032271 (Ensembl Mouse)
SULT1C2
GeneProduct
SULT1C3
GeneProduct
SULT1C4
GeneProduct
SULT2A1
GeneProduct
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
Sult1a1
GeneProduct
ENSMUSG00000030711 (Ensembl Mouse)
Sult1b1
GeneProduct
ENSMUSG00000029269 (Ensembl Mouse)
Sult1c2
GeneProduct
ENSMUSG00000023122 (Ensembl Mouse)
Sult1e1
GeneProduct
ENSMUSG00000029272 (Ensembl Mouse)
Sult2b1
GeneProduct
ENSMUSG00000003271 (Ensembl Mouse)
Sult4a1
GeneProduct
ENSMUSG00000018865 (Ensembl Mouse)
Tpmt
GeneProduct
ENSMUSG00000021376 (Ensembl Mouse)
UGT1A10
GeneProduct
UGT1A5
GeneProduct
UGT1A6
GeneProduct
UGT1A7
GeneProduct
UGT1A9
GeneProduct
UGT2A2
GeneProduct
UGT2B11
GeneProduct
UGT2B15
GeneProduct
UGT2B17
GeneProduct
UGT2B28
GeneProduct
UGT2B4
GeneProduct
UGT2B7
GeneProduct
Ugt1a10
GeneProduct
ENSMUSG00000054545 (Ensembl Mouse)
Ugt1a1
GeneProduct
394436 (Entrez Gene)
Ugt1a2
GeneProduct
22236 (Entrez Gene)
Ugt1a5
GeneProduct
394433 (Entrez Gene)
Ugt2a2
GeneProduct
ENSMUSG00000029268 (Ensembl Mouse)
Ugt2a3
GeneProduct
ENSMUSG00000035780 (Ensembl Mouse)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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External references
DataNodes
Annotated Interactions
No annotated interactions