Eukaryotic transcription initiation (Pan troglodytes)

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(small stable RNAs)Steps 2) Association of TIFs and RNA polymerase5TFIIHSteps 5) RNA elongation with CDT phosphorylationRNA polymerase IITFIIBTFIIESteps 3) DNA melting by association with TFIIHTranscription Initiation Factors (TIFs)TFIIF(recognize surface DNA geometry)TFIIHGene Regulatory ProteinsRNA pol II35TATA Box bindingproteinSteps 4) Transcription elongation by NTPs(large ribosomal RNAs)RNA polymerase ISteps 1) TBP binds TATA boxTATA3dsDNATFIIETFIID5TFIIDTFIIARNA polymerase IIITFIIA33TATATFIIB53TATA555533cell growthPrimary RNA transcript553(mRNA, snRNPs)TFIIFTFIIF3POLR2KRHOXF2POLR2JGTF2H3TAF7GTF2E1ILKTAF6CCNHPOLR1DGTF2F2POLR1BPOLR3EGTF2H1GTF2E2GTF2BERCC3POLR3BTAF9MNAT1POLR3DTAF5TAF12POLR2CPOLR2ICDK7POLR3KGTF2H2TBPPOLR2EPOLR2APOLR1APOLR2GPOLR2FPOLR2BGTF2A2POLR2HERCC2POLR3HTAF13GTF2H4


Description

No description

Comments

GenMAPP notes 
Reference: http://www.web-books.com/MoBio/Free/Ch4E.htm
GenMAPP remarks 
right click for notes & references
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP405(r29565) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Lemon B, Tjian R; ''Orchestrated response: a symphony of transcription factors for gene control.''; Genes Dev, 2000 PubMed Europe PMC Scholia
  2. Lee TI, Young RA; ''Regulation of gene expression by TBP-associated proteins.''; Genes Dev, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117391view10:32, 21 May 2021EweitzModified title
69257view18:37, 8 July 2013MaintBotUpdated to 2013 gpml schema
67218view10:22, 26 June 2013Christine ChichesterOntology Term : 'transcription pathway' added !
48168view20:29, 9 May 2012MaintBotUpdating from human to fix xrefs
41564view01:59, 2 March 2011MaintBotRemoved redundant pathway information and comments
35526view13:57, 12 February 2010Thomasadded literature
35514view13:49, 12 February 2010ThomasModified description
34293view22:02, 9 December 2009MaintBotAutomatic update of empty xrefs
33597view09:55, 1 December 2009MaintBotRemoved group label
31618view22:17, 13 August 2009MaintBotFixed text labels
30517view21:48, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CCNHGeneProduct739351 (Entrez Gene)
CDK7GeneProduct462378 (Entrez Gene)
ERCC2GeneProduct456124 (Entrez Gene)
ERCC3GeneProduct470526 (Entrez Gene)
GTF2A2GeneProduct453483 (Entrez Gene)
GTF2BGeneProduct743356 (Entrez Gene)
GTF2E1GeneProduct460615 (Entrez Gene)
GTF2E2GeneProduct464098 (Entrez Gene)
GTF2F2GeneProduct741868 (Entrez Gene)
GTF2H1GeneProduct748842 (Entrez Gene)
GTF2H2GeneProduct461830 (Entrez Gene)
GTF2H3GeneProduct452352 (Entrez Gene)
GTF2H4GeneProduct462549 (Entrez Gene)
ILKGeneProduct748941 (Entrez Gene)
MNAT1GeneProduct452954 (Entrez Gene)
POLR1AGeneProduct459373 (Entrez Gene)
POLR1BGeneProduct459495 (Entrez Gene)
POLR1DGeneProduct
POLR2AGeneProduct454463 (Entrez Gene)
POLR2BGeneProduct461305 (Entrez Gene)
POLR2CGeneProduct454119 (Entrez Gene)
POLR2EGeneProduct456359 (Entrez Gene)
POLR2FGeneProduct458824 (Entrez Gene)
POLR2GGeneProduct740537 (Entrez Gene)
POLR2HGeneProduct471027 (Entrez Gene)
POLR2IGeneProduct746261 (Entrez Gene)
POLR2JGeneProduct
POLR2KGeneProduct741257 (Entrez Gene)
POLR3BGeneProduct452201 (Entrez Gene)
POLR3DGeneProduct464043 (Entrez Gene)
POLR3EGeneProduct454351 (Entrez Gene)
POLR3HGeneProduct745514 (Entrez Gene)
POLR3KGeneProduct744386 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
TAF12GeneProduct456686 (Entrez Gene)
TAF13GeneProduct738503 (Entrez Gene)
TAF5GeneProduct735428 (Entrez Gene)
TAF6GeneProduct463588 (Entrez Gene)
TAF7GeneProduct471669 (Entrez Gene)
TAF9GeneProduct461833 (Entrez Gene)
TBPGeneProduct738472 (Entrez Gene)

Annotated Interactions

No annotated interactions
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