Hepatocyte growth factor receptor signaling (Mus musculus)
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RHO
pathway
P
RAC1
pathway
Changes in Cytoskeleton
and Cell mobility
Anoikis
P
Transcription
of Cox2
Cytoplasm
Extracellular
AKT Pathway
Right Click for Comments
AP-1
Trancription
Transcription
CDC42
pathway
P
Actin
Map2k1
Elk1
Dock1
Ptk2b
Ptk2b
Stat3
Sos1
Rap1a
Rasa1
Src
Map2k2
Mapk1
Rapgef1
Hgf
Crk
Itgb1
Pak1
Map4k1
Hras1
Mapk3
Ptpn11
Pxn
Gab1
Pik3ca
Mapk8
Ptk2
Met
Src
Rap1b
Grb2
Pten
Fos
Jun
Raf1
Pxn
Itga1
Crkl
Ptk2
Description
No description
Comments
GenMAPP remarks
Converted to human by GenMAPP.org
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP313(r21339)
with a 97% conversion rate.
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
120784
view
01:55, 6 January 2022
Eweitz
Refine case
118815
view
07:59, 2 June 2021
DeSl
Converted "P" to States
118814
view
07:54, 2 June 2021
DeSl
Removed textlabel
118813
view
07:54, 2 June 2021
DeSl
Converted ReceptorSquare to MIM binding with lit. ref.
118812
view
07:51, 2 June 2021
DeSl
Ontology Term : 'hepatocyte' added !
118810
view
07:51, 2 June 2021
DeSl
Ontology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
118808
view
07:50, 2 June 2021
DeSl
Added description from WP313
116711
view
09:44, 11 May 2021
Eweitz
Modified title
88163
view
08:29, 29 July 2016
Mkutmon
graphical lines
69178
view
18:21, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67645
view
11:43, 26 June 2013
Ddigles
Ontology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
41367
view
00:28, 2 March 2011
MaintBot
Removed redundant pathway information and comments
33054
view
19:14, 8 October 2009
Khanspers
added xref
32360
view
13:42, 15 August 2009
MaintBot
Fixed text labels
31994
view
13:15, 14 August 2009
MaintBot
Fixed group labels
31406
view
20:51, 13 August 2009
MaintBot
Fixed text labels
30880
view
00:16, 30 July 2009
MaintBot
Converted from Homo sapiens
21085
view
11:30, 14 November 2008
MaintBot
[[Pathway:Mus musculus:Signaling of Hepatocyte Growth Factor Receptor Biocarta]] moved to [[Pathway:WP193]]: Moved to stable identifier
8386
view
13:46, 7 January 2008
MaintBot
[[Pathway:Mouse:Signaling of Hepatocyte Growth Factor Receptor Biocarta]] moved to [[Pathway:Mus musculus:Signaling of Hepatocyte Growth Factor Receptor Biocarta]]: Renaming species
7810
view
16:19, 18 December 2007
MaintBot
fixed category names
7296
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6493
view
22:19, 22 May 2007
169.230.77.174
gpml file for [[Mouse:Signaling_of_Hepatocyte_Growth_Factor_Receptor_Biocarta]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Crk
GeneProduct
12928 (Entrez Gene)
Crkl
GeneProduct
12929 (Entrez Gene)
Dock1
GeneProduct
330662 (Entrez Gene)
Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
Elk1
GeneProduct
13712 (Entrez Gene)
Fos
GeneProduct
14281 (Entrez Gene)
Gab1
GeneProduct
14388 (Entrez Gene)
Grb2
GeneProduct
14784 (Entrez Gene)
Hgf
GeneProduct
15234 (Entrez Gene)
Hras1
GeneProduct
15461 (Entrez Gene)
Itga1
GeneProduct
109700 (Entrez Gene)
Itgb1
GeneProduct
16412 (Entrez Gene)
Jun
GeneProduct
16476 (Entrez Gene)
Map2k1
GeneProduct
26395 (Entrez Gene)
Map2k2
GeneProduct
26396 (Entrez Gene)
Map4k1
GeneProduct
26411 (Entrez Gene)
Mapk1
GeneProduct
26413 (Entrez Gene)
Mapk3
GeneProduct
26417 (Entrez Gene)
Mapk8
GeneProduct
26419 (Entrez Gene)
Met
GeneProduct
17295 (Entrez Gene)
Pak1
GeneProduct
18479 (Entrez Gene)
Pik3ca
GeneProduct
18706 (Entrez Gene)
Pten
GeneProduct
19211 (Entrez Gene)
Ptk2
GeneProduct
14083 (Entrez Gene)
Ptk2b
GeneProduct
19229 (Entrez Gene)
Ptpn11
GeneProduct
19247 (Entrez Gene)
Pxn
GeneProduct
19303 (Entrez Gene)
Raf1
GeneProduct
110157 (Entrez Gene)
Rap1a
GeneProduct
109905 (Entrez Gene)
Rap1b
GeneProduct
215449 (Entrez Gene)
Rapgef1
GeneProduct
107746 (Entrez Gene)
Rasa1
GeneProduct
218397 (Entrez Gene)
Sos1
GeneProduct
20662 (Entrez Gene)
Son of sevenless homolog 1 (Drosophila) (predicted)
Src
GeneProduct
20779 (Entrez Gene)
Stat3
GeneProduct
20848 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions