Dopamine metabolism (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Jones DR, Moussaud S, McLean P; ''Targeting heat shock proteins to modulate α-synuclein toxicity.''; Ther Adv Neurol Disord, 2014 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	107129	view	14:21, 17 September 2019	MaintBot	ChEBI identifier normalization
	106713	view	13:15, 17 September 2019	MaintBot	HMDB identifier normalization
	106389	view	21:26, 28 August 2019	Khanspers	Modified description
	105571	view	06:27, 9 August 2019	Khanspers	Modified description
	98240	view	14:02, 14 August 2018	Egonw	Replace a PubChem SID with a Wikidata ID (which has more links out).
	97673	view	11:17, 1 June 2018	AMTan	Ontology Term : 'dopaminergic neuron' added !
	96040	view	16:00, 15 February 2018	Mkutmon	remove old pathway attributes
	96039	view	15:59, 15 February 2018	Mkutmon	add literature reference
	96037	view	15:52, 15 February 2018	Mkutmon	Modified description
	96036	view	15:52, 15 February 2018	Mkutmon	Modified description
	94675	view	13:47, 4 October 2017	Marvin M2	Connected unconnected lines
	93092	view	13:44, 28 July 2017	DeSl	Changed 4 pubchem substance IDs to other with more stereospecificity (except for Neuromelanin)
	93090	view	13:38, 28 July 2017	DeSl	Ontology Term : 'dopamine metabolic pathway' added !
	93089	view	13:38, 28 July 2017	DeSl	Ontology Term : 'dopamine degradation pathway' added !
	93088	view	13:38, 28 July 2017	DeSl	Ontology Term : 'dopamine biosynthetic pathway' added !
	90505	view	14:00, 19 November 2016	Egonw	Ontology Term : 'classic metabolic pathway' added !
	71387	view	18:41, 17 October 2013	MaintBot	Automated update of data sources
	68759	view	14:50, 7 July 2013	Egonw	Typo :(
	68758	view	14:45, 7 July 2013	Egonw	Fixed PubChem identifier structure, and one PubChem data source name.
	68757	view	14:42, 7 July 2013	Egonw	Fixed ChEBI identifier structure.
	68756	view	14:41, 7 July 2013	Egonw	Fixed the data source to HMDB.
	67956	view	14:38, 28 June 2013	MaintBot	Ontology Term : 'dopaminergic pathway' added !
	67955	view	14:36, 28 June 2013	MaintBot	Ontology Term : 'PW:0000394' removed !
	61605	view	07:05, 15 April 2013	Mostaszewski	homovanilic acid and dopaminochrome added
	57740	view	22:19, 1 February 2013	MaintBot	Modified categories
	56800	view	13:41, 14 January 2013	Mostaszewski	minor layout correction
	56797	view	13:31, 14 January 2013	Mostaszewski	Ontology Term : 'Parkinson disease pathway' added !
	56796	view	13:31, 14 January 2013	Mostaszewski	Ontology Term : 'dopaminergic pathway' added !
	56795	view	13:26, 14 January 2013	Mostaszewski	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
4a-Hydroxytetrahydrobiopterin	Metabolite	HMDB02281 (HMDB)
5,6-Dihydroxyindole	Metabolite	HMDB04058 (HMDB)
5-glutathionyl dopamine	Metabolite
CO2	Metabolite	HMDB01967 (HMDB)
DDC	GeneProduct	1644 (Entrez Gene)
DHICA	Metabolite	HMDB01253 (HMDB)
Dopamine quinone	Metabolite	HMDB12219 (HMDB)
Dopamine semiquinone	Metabolite
Dopamine	Metabolite	HMDB00073 (HMDB)
Dopaminochrome	Metabolite	SID135653506 (PubChem-substance)
Glutathione	Metabolite	HMDB00125 (HMDB)
ICQA	Metabolite	SID96022279 (PubChem-substance)
L-Dopa quinone	Metabolite	CHEBI16852 (ChEBI)
L-Dopa	Metabolite	HMDB00181 (HMDB)
L-Dopachrome	Metabolite	HMDB01430 (HMDB)
L-Tyrosine	Metabolite	HMDB00158 (HMDB)
Leucodopachrome	Metabolite	HMDB04067 (HMDB)
Leukoaminochrome	Metabolite	HMDB12992 (HMDB)
NQO1	GeneProduct	1728 (Entrez Gene)
Neuromelanin	Metabolite	SID136368185 (PubChem-substance)
PPP2CA	GeneProduct	5515 (Entrez Gene)
PPP2CB	GeneProduct	5516 (Entrez Gene)
PRKACA	GeneProduct	5566 (Entrez Gene)
PRKACB	GeneProduct	5567 (Entrez Gene)
PRKACG	GeneProduct	5568 (Entrez Gene)
SOD1	GeneProduct	6647 (Entrez Gene)
TH	GeneProduct	7054 (Entrez Gene)
TYR	GeneProduct	7299 (Entrez Gene)
Tetrahydrobiopterin	Metabolite	HMDB00027 (HMDB)
iron(2+)	Metabolite	CHEBI29033 (ChEBI)

Annotated Interactions

No annotated interactions