TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc) (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Name: New Pathway


Description

No description

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View approved pathways at the new wikipathways.org.

Quality Tags

Image:NeedsRef.pngAdd references
Image:Curated.pngReview changes for Approved

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
137810
Approved
view06:37, 8 March 2025EgonwModified description
123103view08:58, 3 July 2022EgonwMade a pathway clickable
117835view15:11, 22 May 2021EweitzModified title
107130view14:21, 17 September 2019MaintBotChEBI identifier normalization
105833view23:08, 15 August 2019KhanspersModified description
96056view16:30, 15 February 2018Mkutmonremoved old pathway attributes
96055view16:28, 15 February 2018MkutmonModified description
96054view16:28, 15 February 2018MkutmonModified description
94220view22:19, 25 August 2017DeSlAdded IDs for 3 missing metabolites
87731view09:25, 25 July 2016MirellaKalafatiOntology Term : 'pyruvate dehydrogenase complex deficiency pathway' added !
87724view09:20, 25 July 2016MirellaKalafatiOntology Term : 'PW:0000002' removed !
87723view09:19, 25 July 2016MirellaKalafatiOntology Term : 'disease pathway' added !
87722view09:19, 25 July 2016MirellaKalafatiOntology Term : 'citric acid cycle pathway' added !
87721view09:19, 25 July 2016MirellaKalafatiOntology Term : 'classic metabolic pathway' added !
87720view09:18, 25 July 2016MirellaKalafatiModified title
87376view09:56, 22 July 2016MaintBotadded missing graphids
80143view17:16, 14 May 2015Khanspersupdated xrefs
80142view17:11, 14 May 2015Khanspersfixed connections, updated annotations
78495view10:28, 7 January 2015MaintBotadded missing graphIds
72092view21:32, 24 October 2013Mkutmonadded datasource for "Lipoamide-E"
71271view22:16, 16 October 2013MaintBotAutomated update of data sources
69020view17:49, 8 July 2013MaintBotUpdated to 2013 gpml schema
58689view18:30, 19 February 2013MaintBotModified categories
58688view18:29, 19 February 2013MaintBotModified title
58472view20:36, 13 February 2013Maguirre1FINAL v1.0
58471view20:31, 13 February 2013Maguirre1Periodical save, work in progress
58470view20:20, 13 February 2013Maguirre1Periodical save, work in progress
58469view20:10, 13 February 2013Maguirre1Periodical save, work in progress
58468view20:00, 13 February 2013Maguirre1Periodical save, work in progress
58467view19:50, 13 February 2013Maguirre1Periodical save, work in progress
58466view19:40, 13 February 2013Maguirre1Periodical save, work in progress
58465view19:30, 13 February 2013Maguirre1Periodical save, work in progress
58464view19:20, 13 February 2013Maguirre1Periodical save, work in progress
58463view19:10, 13 February 2013Maguirre1Periodical save, work in progress
58461view19:00, 13 February 2013Maguirre1Periodical save, work in progress
58460view18:49, 13 February 2013Maguirre1New pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
(S)-MalateMetaboliteC00149 (Kegg Compound)
2-Hydroxy-ethyl- ThPPMetaboliteC05125 (Kegg Compound)
2-Oxo-glutarateMetaboliteC00026 (Kegg Compound)
3-carboxy-1- hydroxypropyl-ThPPMetabolite
ACO1GeneProductK01681 (KEGG Orthology)
ATPCLGeneProductK01648 (KEGG Orthology)
Acetyl-CoAMetaboliteC00024 (Kegg Compound)
CSGeneProductK01647 (KEGG Orthology)
CitrateMetaboliteC00158 (Kegg Compound)
DLATGeneProductK00627 (KEGG Orthology)
DLDGeneProductK00382 (KEGG Orthology)
DLSTGeneProductK00658 (KEGG Orthology)
Dihydro- lipoamide-EMetabolite
FHGeneProductK01679 (KEGG Orthology)
FumarateMetaboliteC00122 (Kegg Compound)
GlycolysisPathway
IDH1GeneProductK00031 (KEGG Orthology)
IDH3AGeneProductK00030 (KEGG Orthology)
IsocitrateMetaboliteC00311 (Kegg Compound)
Lipoamide-EMetaboliteC15972
MDH1GeneProductK00025 (KEGG Orthology)
OGDHGeneProductK00164 (KEGG Orthology)
OxaloacetateMetaboliteC00036 (Kegg Compound)
OxalosuccinateMetaboliteC05379 (Kegg Compound)
PCBGeneProduct
PCK1GeneProduct
PDHA1GeneProductK00161 (KEGG Orthology)
Phosphoenol- pyruvateMetaboliteC00074 (Kegg Compound)
PyruvateMetaboliteC00022 (Kegg Compound)
S-Acetyldihydro- lipoamide-EMetaboliteC16255 (Kegg Compound)
S-Succinyl- dihydrolipoamide-EMetabolite
SDHAGeneProductK00234 (KEGG Orthology)
SUCLG2GeneProductK01900 (KEGG Orthology)
SuccinateMetaboliteC00042 (Kegg Compound)
Succinoyl-CoAMetaboliteC00091 (Kegg Compound)
ThPPMetaboliteC00068 (Kegg Compound)

Annotated Interactions

No annotated interactions

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