Prostaglandin synthesis and regulation (Bos taurus)

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prolactinreleaseCytoplasmCell MembranePhospholipidsCortisoneGq signalingpathwayPG SynthasesInactive MetabolitesANXA8CYP11A1PTGER1PRLPTGER2PLA2G4AANXA6PTGDSPGF2aTBXAS1EDNRAPTGDREDNRBCalciumPTGISANXA3ANXA1ProgesteroneS100A10TXA2PTGS2PTGER3PGF2aLOC618256CortisolHPGDSCGB1A1Prostaglandin H2PGI2ANXA4PGE2HSD11B2HSD11B1PTGER4EDN1CalciumPTGIRANXA5Arachidonic AcidCortisolPTGS1ANXA2PTGFR


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 80% conversion rate.

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Ontology Terms

 

Bibliography

  1. Gross G, Imamura T, Muglia LJ; ''Gene knockout mice in the study of parturition.''; J Soc Gynecol Investig, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117590view11:25, 21 May 2021EweitzModified title
113600view14:02, 4 November 2020DeSlUpdating IDs for cortisol to avoid duplicate mappings (2x)
111161view09:22, 21 July 2020EgonwMade another pathway clickable
105989view11:51, 16 August 2019MaintBotHMDB identifier normalization
80872view15:29, 30 June 2015Mkutmonhomology conversion
71430view19:03, 17 October 2013MaintBotAutomated update of data sources
63464view17:19, 10 May 2013MaintBotUpdated to 2013 gpml schema
40599view19:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
33836view00:30, 9 December 2009MaintBotAutomatic update of empty xrefs
33636view10:06, 1 December 2009MaintBotRemoved group label
31642view22:27, 13 August 2009MaintBotFixed text labels
30564view22:04, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ANXA1GeneProduct327662 (Entrez Gene)
ANXA2GeneProduct282689 (Entrez Gene)
ANXA3GeneProduct518050 (Entrez Gene)
ANXA4GeneProduct281625 (Entrez Gene)
ANXA5GeneProduct281626 (Entrez Gene)
ANXA6GeneProduct327685 (Entrez Gene)
ANXA8GeneProduct
Arachidonic AcidMetabolite
CYP11A1GeneProduct338048 (Entrez Gene)
CalciumMetaboliteHMDB00464 (HMDB)
CortisolMetabolite
EDN1GeneProduct281137 (Entrez Gene) PMID: 1474344
EDNRAGeneProduct281749 (Entrez Gene)
EDNRBGeneProduct281750 (Entrez Gene)
HPGDGeneProduct512259 (Entrez Gene)
HSD11B1GeneProduct282589 (Entrez Gene)
HSD11B2GeneProduct282434 (Entrez Gene)
LOC618256GeneProduct618256 (Entrez Gene)
PGE2MetaboliteHMDB03175 (HMDB)
PGF2aMetaboliteHMDB01139 (HMDB)
PGI2MetaboliteHMDB01335 (HMDB)
PLA2G4AGeneProduct525072 (Entrez Gene)
PRLGeneProduct280901 (Entrez Gene)
PTGDRGeneProduct515331 (Entrez Gene)
PTGDSGeneProduct286858 (Entrez Gene)
PTGER1GeneProduct507437 (Entrez Gene)
PTGER2GeneProduct282329 (Entrez Gene)
PTGER3GeneProduct282330 (Entrez Gene)
PTGER4GeneProduct282331 (Entrez Gene)
PTGFRGeneProduct282020 (Entrez Gene)
PTGIRGeneProduct520278 (Entrez Gene)
PTGISGeneProduct282021 (Entrez Gene)
PTGS1GeneProduct282022 (Entrez Gene)
PTGS2GeneProduct282023 (Entrez Gene)
ProgesteroneMetabolite
Prostaglandin H2Metabolite
S100A10GeneProduct282466 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
SCGB1A1GeneProductPMID: 7615804, PMID: 3292559
TBXAS1GeneProduct509326 (Entrez Gene)
TXA2MetaboliteHMDB01452 (HMDB)

Annotated Interactions

No annotated interactions
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