Metapathway biotransformation (Mus musculus)
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Amino acid acyl transferases
Glucuronidation
Glutathione reductase
Electrophiles
N-acetyltransferases
Glutathione peroxidases
Flavin monooxygenases
Reduction
Hydrolysis
Glutathione conjugation
Oxidation
Aldo-keto reductases
Sulfotransferases
Methylation
Amino acid conjugation
Glucuronosyltransferases
Sulfation
Acetylation
Glutathione transferases
Nucleophiles
Methyltransferases
Epoxide hydrolases
Glutathione synthetase
Cytochrome P450
AKR1C4
Cyp4x1
Tpmt
Nat8l
Akr1a4
Gal3st3
Gpx4
Cyp26a1
Cyp4b1
Flavin monooxygenase
Ndst3
AC140307.3-1
Cyp2u1
Chst11
Gstm7
Chst5
CYP2J2
Ugt1a10
Substrate-SG
CYP2D6
Gsto1
UGT1A6
Substrate-SH
GSTM4
Ndst4
AKR7A3
Cyp2r1
Kcnab3
Cyp4f39
Akr1d1
Cyp20a1
Cyp19a1
Mgst3
Hs6st1
Akr7a5
Akr1b3
Amino acid acyltransferase
Cyp24a1
Gstt1
NAT1
GSTA5
Cyp7a1
Chst2
CYP4F12
N-acetyltransferase
Substrate-SO3H
Aldo-keto reductase
Fmo5
Hs3st6
Gss
GLYATL2
Gal3st4
Gsto2
UGT1A5
SULT1C3
Nat12
Chst4
Nnmt
Sult1e1
CYP11B2
CYP2B6
Ugt2a3
Sult2b1
Chst10
Cyp17a1
CYP2C8
Cyp26b1
Comt1
Sult4a1
Nat5
UGT1A10
Gstcd
Chst3
HS3ST3B1
GLYATL1
GSTA3
Hs3st4
Gstz1
GSTP1
Fmo2
Gpx3
CYP3A43
AC154274.1-1
Sult1b1
Ndst2
Fmo1
UGT1A9
Chst7
Hs6st2
Nat6
GSTM5
Gal3st1
AKR1B10
Gstt2
Glyat
Cyp46a1
CYP3A5
Cyp1a2
Chst14
Cyp11a1
Hs3st1
Cyp2f2
UGT2B11
CYP4F2
Cyp21a1
Substrate-O-R
NAT2
SULT1C4
Ugt2a2
Ugt1a1
Ephx1
Sult1a1
Cyp8b1
Ephx2
NAT8
Sult1c2
Gpx1
Kcnab1
Hnmt
Baat
Hs2st1
Substrate-Ac
Gstm5
Cyp7b1
UGT2B17
UGT1A7
Chst12
Cyp2s1
UGT2B15
Cyp27a1
Chst9
GAL3ST2
HS3ST3A1
Cyp2e1
Ugt1a2
Gstt2
CYP2C9
AC122521.4
Cyp51
Glutathione transferase
UGT2B7
Mgst1
Sult1a1
Cyp39a1
Nat13
Nat9
Kcnab2
Substrate-OH
AKR1C1
Nat10
Gpx2
AC161058.2-1
Mgst2
Cyp4f18
AKR1C2
CYP2A7
Chst1
Xenobiotic substrate
Ndst1
CYP2A13
Glucuronosyltransferase
CYP2C19
Cyp26c1
Substrate-Gl
UGT2B4
CYP27C1
Chst5
Methyltransferase
Cyp27b1
Hs3st5
Ugt1a5
Sult1a1
Sult1a1
Nat14
Substrate-NH2
Cyp1a1
CYP2C18
Cyp1b1
AKR1C3
GSTA2
CYP11B1
Gstk1
Fmo4
GSTM1
UGT2A2
Gpx5
Gsr
CYP4Z1
CYP4F11
CYP450
Chst8
CYP3A4
Substrate=O
Cyp4v3
Inmt
CYP4F8
Hs3st2
SULT2A1
Sulfotransferase
Substrate-Aa
CYP2A6
Hs6st3
Substrate-CH3
CYP3A7
Fmo3
UGT2B28
SULT1C2
GSTA4
GSTA1
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 64% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
94721
view
14:08, 5 October 2017
Egonw
Converted two complexes (which they are not) to groups.
94720
view
14:04, 5 October 2017
Egonw
Mim-typed interactions.
69747
view
09:37, 11 July 2013
Egonw
Added ChEBI identifiers for a few compound classes.
69160
view
18:19, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67456
view
11:04, 26 June 2013
Ddigles
Ontology Term : 'cellular detoxification pathway' added !
59060
view
21:01, 21 February 2013
MaintBot
Updated Ensembl and UniProt data source
58513
view
19:13, 14 February 2013
MaintBot
Modified title
41349
view
00:26, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34408
view
23:07, 9 December 2009
MaintBot
Automatic update of empty xrefs
33190
view
18:06, 5 November 2009
Khanspers
Modified categories
32293
view
13:12, 15 August 2009
MaintBot
Fixed text labels
31856
view
12:33, 14 August 2009
MaintBot
Fixed group labels
31321
view
20:17, 13 August 2009
MaintBot
Fixed text labels
30847
view
00:06, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AC122521.4
GeneProduct
ENSMUSG00000056643 (Ensembl)
AC140307.3-1
GeneProduct
ENSMUSG00000024764 (Ensembl)
AC154274.1-1
GeneProduct
ENSMUSG00000038045 (Ensembl)
AC161058.2-1
GeneProduct
ENSMUSG00000029541 (Ensembl)
AKR1B10
GeneProduct
67861 (Entrez Gene)
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
AKR1C4
GeneProduct
AKR7A3
GeneProduct
Akr1a4
GeneProduct
ENSMUSG00000028692 (Ensembl)
Akr1b3
GeneProduct
ENSMUSG00000001642 (Ensembl)
Akr1d1
GeneProduct
ENSMUSG00000038641 (Ensembl)
Akr7a5
GeneProduct
ENSMUSG00000028743 (Ensembl)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
Baat
GeneProduct
ENSMUSG00000039653 (Ensembl)
CYP11B1
GeneProduct
110115 (Entrez Gene)
CYP11B2
GeneProduct
13072 (Entrez Gene)
CYP27C1
GeneProduct
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2B6
GeneProduct
CYP2C18
GeneProduct
CYP2C19
GeneProduct
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
CYP2J2
GeneProduct
CYP3A4
GeneProduct
CYP3A43
GeneProduct
CYP3A5
GeneProduct
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F2
GeneProduct
CYP4F8
GeneProduct
CYP4Z1
GeneProduct
Chst10
GeneProduct
ENSMUSG00000026080 (Ensembl)
Chst11
GeneProduct
ENSMUSG00000034612 (Ensembl)
Chst12
GeneProduct
ENSMUSG00000036599 (Ensembl)
Chst14
GeneProduct
72136 (Entrez Gene)
Chst1
GeneProduct
ENSMUSG00000027221 (Ensembl)
Chst2
GeneProduct
ENSMUSG00000033350 (Ensembl)
Chst3
GeneProduct
ENSMUSG00000057337 (Ensembl)
Chst4
GeneProduct
ENSMUSG00000035930 (Ensembl)
Chst5
GeneProduct
ENSMUSG00000031952 (Ensembl)
Chst7
GeneProduct
ENSMUSG00000037347 (Ensembl)
Chst8
GeneProduct
ENSMUSG00000060402 (Ensembl)
Chst9
GeneProduct
71367 (Entrez Gene)
Comt1
GeneProduct
ENSMUSG00000000326 (Ensembl)
Cyp11a1
GeneProduct
ENSMUSG00000032323 (Ensembl)
Cyp17a1
GeneProduct
ENSMUSG00000003555 (Ensembl)
Cyp19a1
GeneProduct
ENSMUSG00000032274 (Ensembl)
Cyp1a1
GeneProduct
ENSMUSG00000032315 (Ensembl)
Cyp1a2
GeneProduct
ENSMUSG00000032310 (Ensembl)
Cyp1b1
GeneProduct
ENSMUSG00000024087 (Ensembl)
Cyp20a1
GeneProduct
ENSMUSG00000049439 (Ensembl)
Cyp21a1
GeneProduct
13079 (Entrez Gene)
Cyp24a1
GeneProduct
ENSMUSG00000038567 (Ensembl)
Cyp26a1
GeneProduct
ENSMUSG00000024987 (Ensembl)
Cyp26b1
GeneProduct
ENSMUSG00000063415 (Ensembl)
Cyp26c1
GeneProduct
ENSMUSG00000062432 (Ensembl)
Cyp27a1
GeneProduct
ENSMUSG00000026170 (Ensembl)
Cyp27b1
GeneProduct
ENSMUSG00000006724 (Ensembl)
Cyp2e1
GeneProduct
ENSMUSG00000025479 (Ensembl)
Cyp2f2
GeneProduct
ENSMUSG00000052974 (Ensembl)
Cyp2r1
GeneProduct
ENSMUSG00000030670 (Ensembl)
Cyp2s1
GeneProduct
ENSMUSG00000040703 (Ensembl)
Cyp2u1
GeneProduct
ENSMUSG00000027983 (Ensembl)
Cyp39a1
GeneProduct
ENSMUSG00000023963 (Ensembl)
Cyp46a1
GeneProduct
ENSMUSG00000021259 (Ensembl)
Cyp4b1
GeneProduct
ENSMUSG00000028713 (Ensembl)
Cyp4f18
GeneProduct
ENSMUSG00000003484 (Ensembl)
Cyp4f39
GeneProduct
ENSMUSG00000061126 (Ensembl)
Cyp4v3
GeneProduct
ENSMUSG00000079057 (Ensembl)
Cyp4x1
GeneProduct
ENSMUSG00000047155 (Ensembl)
Cyp51
GeneProduct
ENSMUSG00000001467 (Ensembl)
Cyp7a1
GeneProduct
ENSMUSG00000028240 (Ensembl)
Cyp7b1
GeneProduct
ENSMUSG00000039519 (Ensembl)
Cyp8b1
GeneProduct
ENSMUSG00000050445 (Ensembl)
Ephx1
GeneProduct
ENSMUSG00000038776 (Ensembl)
Ephx2
GeneProduct
ENSMUSG00000022040 (Ensembl)
Flavin monooxygenase
GeneProduct
Fmo1
GeneProduct
ENSMUSG00000040181 (Ensembl)
Fmo2
GeneProduct
ENSMUSG00000040170 (Ensembl)
Fmo3
GeneProduct
ENSMUSG00000026691 (Ensembl)
Fmo4
GeneProduct
ENSMUSG00000026692 (Ensembl)
Fmo5
GeneProduct
ENSMUSG00000028088 (Ensembl)
GAL3ST2
GeneProduct
381334 (Entrez Gene)
GLYATL1
GeneProduct
GLYATL2
GeneProduct
GSTA1
GeneProduct
14857 (Entrez Gene)
GSTA2
GeneProduct
14858 (Entrez Gene)
GSTA3
GeneProduct
14859 (Entrez Gene)
GSTA4
GeneProduct
14860 (Entrez Gene)
GSTA5
GeneProduct
GSTM1
GeneProduct
14862 (Entrez Gene)
GSTM4
GeneProduct
14865 (Entrez Gene)
GSTM5
GeneProduct
14866 (Entrez Gene)
GSTP1
GeneProduct
14870 (Entrez Gene)
Gal3st1
GeneProduct
ENSMUSG00000049721 (Ensembl)
Gal3st3
GeneProduct
ENSMUSG00000047658 (Ensembl)
Gal3st4
GeneProduct
ENSMUSG00000075593 (Ensembl)
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
Glyat
GeneProduct
ENSMUSG00000063683 (Ensembl)
Gpx1
GeneProduct
ENSMUSG00000063856 (Ensembl)
Gpx2
GeneProduct
ENSMUSG00000042808 (Ensembl)
Gpx3
GeneProduct
ENSMUSG00000018339 (Ensembl)
Gpx4
GeneProduct
ENSMUSG00000075706 (Ensembl)
Gpx5
GeneProduct
ENSMUSG00000004344 (Ensembl)
Gsr
GeneProduct
ENSMUSG00000031584 (Ensembl)
Gss
GeneProduct
ENSMUSG00000027610 (Ensembl)
Gstcd
GeneProduct
ENSMUSG00000028018 (Ensembl)
Gstk1
GeneProduct
ENSMUSG00000029864 (Ensembl)
Gstm5
GeneProduct
ENSMUSG00000004032 (Ensembl)
Gstm7
GeneProduct
ENSMUSG00000004035 (Ensembl)
Gsto1
GeneProduct
ENSMUSG00000025068 (Ensembl)
Gsto2
GeneProduct
ENSMUSG00000025069 (Ensembl)
Gstt1
GeneProduct
ENSMUSG00000001663 (Ensembl)
Gstt2
GeneProduct
ENSMUSG00000033318 (Ensembl)
Gstz1
GeneProduct
ENSMUSG00000021033 (Ensembl)
HS3ST3A1
GeneProduct
15478 (Entrez Gene)
HS3ST3B1
GeneProduct
54710 (Entrez Gene)
Hnmt
GeneProduct
ENSMUSG00000026986 (Ensembl)
Hs2st1
GeneProduct
ENSMUSG00000040151 (Ensembl)
Hs3st1
GeneProduct
ENSMUSG00000051022 (Ensembl)
Hs3st2
GeneProduct
ENSMUSG00000046321 (Ensembl)
Hs3st4
GeneProduct
ENSMUSG00000078591 (Ensembl)
Hs3st5
GeneProduct
ENSMUSG00000044499 (Ensembl)
Hs3st6
GeneProduct
ENSMUSG00000039628 (Ensembl)
Hs6st1
GeneProduct
ENSMUSG00000045216 (Ensembl)
Hs6st2
GeneProduct
ENSMUSG00000062184 (Ensembl)
Hs6st3
GeneProduct
ENSMUSG00000053465 (Ensembl)
Inmt
GeneProduct
ENSMUSG00000003477 (Ensembl)
Kcnab1
GeneProduct
ENSMUSG00000027827 (Ensembl)
Kcnab2
GeneProduct
ENSMUSG00000028931 (Ensembl)
Kcnab3
GeneProduct
ENSMUSG00000018470 (Ensembl)
Methyltransferase
GeneProduct
Mgst1
GeneProduct
ENSMUSG00000008540 (Ensembl)
Mgst2
GeneProduct
ENSMUSG00000074604 (Ensembl)
Mgst3
GeneProduct
ENSMUSG00000026688 (Ensembl)
N-acetyltransferase
GeneProduct
NAT1
GeneProduct
NAT2
GeneProduct
17961 (Entrez Gene)
NAT8
GeneProduct
68396 (Entrez Gene)
Nat10
GeneProduct
ENSMUSG00000027185 (Ensembl)
Nat12
GeneProduct
ENSMUSG00000036282 (Ensembl)
Nat13
GeneProduct
ENSMUSG00000022698 (Ensembl)
Nat14
GeneProduct
ENSMUSG00000035285 (Ensembl)
Nat5
GeneProduct
ENSMUSG00000002728 (Ensembl)
Nat6
GeneProduct
ENSMUSG00000079334 (Ensembl)
Nat8l
GeneProduct
ENSMUSG00000048142 (Ensembl)
Nat9
GeneProduct
ENSMUSG00000015542 (Ensembl)
Ndst1
GeneProduct
ENSMUSG00000054008 (Ensembl)
Ndst2
GeneProduct
ENSMUSG00000039308 (Ensembl)
Ndst3
GeneProduct
ENSMUSG00000027977 (Ensembl)
Ndst4
GeneProduct
ENSMUSG00000027971 (Ensembl)
Nnmt
GeneProduct
ENSMUSG00000032271 (Ensembl)
SULT1C2
GeneProduct
69083 (Entrez Gene)
SULT1C3
GeneProduct
SULT1C4
GeneProduct
SULT2A1
GeneProduct
20859 (Entrez Gene)
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
Sult1a1
GeneProduct
ENSMUSG00000030711 (Ensembl)
Sult1b1
GeneProduct
ENSMUSG00000029269 (Ensembl)
Sult1c2
GeneProduct
ENSMUSG00000023122 (Ensembl)
Sult1e1
GeneProduct
ENSMUSG00000029272 (Ensembl)
Sult2b1
GeneProduct
ENSMUSG00000003271 (Ensembl)
Sult4a1
GeneProduct
ENSMUSG00000018865 (Ensembl)
Tpmt
GeneProduct
ENSMUSG00000021376 (Ensembl)
UGT1A10
GeneProduct
394430 (Entrez Gene)
UGT1A5
GeneProduct
394433 (Entrez Gene)
UGT1A6
GeneProduct
UGT1A7
GeneProduct
UGT1A9
GeneProduct
394434 (Entrez Gene)
UGT2A2
GeneProduct
552899 (Entrez Gene)
UGT2B11
GeneProduct
UGT2B15
GeneProduct
UGT2B17
GeneProduct
UGT2B28
GeneProduct
UGT2B4
GeneProduct
UGT2B7
GeneProduct
Ugt1a10
GeneProduct
ENSMUSG00000054545 (Ensembl)
Ugt1a1
GeneProduct
394436 (Entrez Gene)
Ugt1a2
GeneProduct
22236 (Entrez Gene)
Ugt1a5
GeneProduct
394433 (Entrez Gene)
Ugt2a2
GeneProduct
ENSMUSG00000029268 (Ensembl)
Ugt2a3
GeneProduct
ENSMUSG00000035780 (Ensembl)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
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External references
DataNodes
Annotated Interactions
No annotated interactions