Regulation of actin cytoskeleton (Rattus norvegicus)
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RAS
RAS
stress fiber
RTK
Focal complex
assembly
Lamellipodia
Filipodia
-p
GF
MAPK Signaling
pathway
Actin
polymerization
Stabilization
of actin
+p
Focal adhesion
pathway
Chemotactic factor
PI3K
GPCR
Actin polymerization
stress fiber
Growth Factor (GF)
Focal adhesion
assembly
RTK
?
PI3K
Actin polymerization
Gene Expression
Actomyosin
assembly contraction
GPCR
Chemotatic factor
Focal adhesion
pathway
Adherens junction
pathway
Fgf4
Apc2
PIP2
Mapk6
Ins1
Ssh2
Pdgfra
Mapk1
Chrm2
Fgfr1
Pip4k2b
Braf
Rras
Acetylcholine
Pak6
Cd14
Fgf23
Actg1
Fgf22
Pik3r4
Pdgfrb
Fgf11
Bradykinin
Arhgef6
Myl3
Csk
Pxn
Pik3cg
Mapk4
Kras
Fgf12
Fgf20
Fgf8
PIK3CA
Pfn1
Raf1
Pik3c2g
Fgf9
Vcl
Fgf21
Enah
Pik3r3
Pik3c3
Ezr
Nras
Fgf14
Limk1
Arhgef7
Arpc5
Fgfr2
Fgf16
DIAP3
Rock2
PIP2
Vil1
DIAP1
SOS2
Fgf2
Sos1
Fgf1
Pik3r1
Chrm3
Pak4
F2
Fn1
Fgfr4
Mapk3
PIP5KL1
Rassf7
FGF18
Pip4k2c
Pak3
Actb
Vcl
WAS
Gsn
Pik3r2
Fgfr3
Pip5k1c
Pip4k2a
Baiap2
Fgf15
Fgf17
Gng12
Arhgef4
Pdgfb
Pik3r5
Actb
Myh10
c3orf10
Pik3c2a
Itga1
Bdkrb1
Rras2
Fgf3
F2r
Pdgfa
Fgf7
Mos
Chrm4
Mylk
Rac1
Actn1
CDC42
Pak2
LOC442775
Fgf6
Apc
Baiap2
Pip4k2a
Chrm1
Wasf1
Actg1
Bcar1
Cfl1
Map2k1
Iqgap1
Abi2
Myl1
Bdkrb2
Pik3cd
Mras
Actb
Pip5k1b
LPS
CYFIP2
Slc9a1
Pak7
RAC3
Grlf1
Fgd1
Rock1
Ppp1r12a
PIP5K1A
Fgf5
Arpc5
TMSB4X
Egfr
Rac2
Pik3c2b
Pak1
Gna13
Rhoa
Rdx
Crk
Git1
Ptk2
Egf
Arhgef6
Msn
Map2k2
Actg1
Wasf2
RAC1P4
Fgf13
Gna12
Ins2
Nckap1
Pfn1
Ssh3
Cfl2
Pik3cb
Dock1
Fgf10
Ssh1
Vav1
Arhgef1
PIP3
Chrm5
Description
No description
Comments
GenMAPP notes
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks
Adapted from KEGG (right-click to see notes)
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r20783)
with a 90% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
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Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
117008
view
11:21, 16 May 2021
Eweitz
Modified title
109392
view
16:03, 16 March 2020
L Dupuis
Converted interactions to graphical lines
105000
view
04:50, 28 June 2019
Khanspers
removed KEGG comments
72164
view
12:24, 25 October 2013
Egonw
Added missing metabolite IDs.
71785
view
20:32, 17 October 2013
MaintBot
Automated update of data sources
71299
view
16:58, 17 October 2013
MaintBot
Automated update of data sources
69385
view
18:57, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67622
view
11:34, 26 June 2013
Ddigles
Ontology Term : 'cell adhesion signaling pathway' added !
47758
view
05:00, 6 April 2012
Khanspers
updated xref
47757
view
04:58, 6 April 2012
Khanspers
updated xrefs
41701
view
02:37, 2 March 2011
MaintBot
Removed redundant pathway information and comments
34083
view
19:13, 9 December 2009
MaintBot
Automatic update of empty xrefs
32406
view
17:03, 15 August 2009
MaintBot
Fixed text labels
32061
view
13:34, 14 August 2009
MaintBot
Fixed group labels
31436
view
21:04, 13 August 2009
MaintBot
Fixed text labels
31003
view
01:01, 30 July 2009
MaintBot
Converted from Homo sapiens
21415
view
11:31, 14 November 2008
MaintBot
[[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:WP351]]: Moved to stable identifier
8358
view
13:46, 7 January 2008
MaintBot
[[Pathway:Rat:Regulation of Actin Cytoskeleton KEGG]] moved to [[Pathway:Rattus norvegicus:Regulation of Actin Cytoskeleton KEGG]]: Renaming species
7797
view
16:18, 18 December 2007
MaintBot
fixed category names
7291
view
12:41, 4 November 2007
MaintBot
Added categories to GPML
6590
view
22:20, 22 May 2007
169.230.77.174
gpml file for [[Rat:Regulation_of_Actin_Cytoskeleton_KEGG]]
External references
DataNodes
View all...
Name
Type
Database reference
Comment
Abi2
GeneProduct
286928 (Entrez Gene)
Acetylcholine
Metabolite
Actb
GeneProduct
81822 (Entrez Gene)
Actg1
GeneProduct
287876 (Entrez Gene)
Actn1
GeneProduct
81634 (Entrez Gene)
Apc2
GeneProduct
299611 (Entrez Gene)
Apc
GeneProduct
24205 (Entrez Gene)
Arhgef1
GeneProduct
60323 (Entrez Gene)
Arhgef4
GeneProduct
301334 (Entrez Gene)
Arhgef6
GeneProduct
363509 (Entrez Gene)
Arhgef7
GeneProduct
114559 (Entrez Gene)
Arpc5
GeneProduct
360854 (Entrez Gene)
Baiap2
GeneProduct
117542 (Entrez Gene)
Bcar1
GeneProduct
25414 (Entrez Gene)
Bdkrb1
GeneProduct
81509 (Entrez Gene)
Bdkrb2
GeneProduct
25245 (Entrez Gene)
Bradykinin
Metabolite
Braf
GeneProduct
114486 (Entrez Gene)
CDC42
GeneProduct
64465 (Entrez Gene)
CYFIP2
GeneProduct
303073 (Entrez Gene)
Cd14
GeneProduct
60350 (Entrez Gene)
Cfl1
GeneProduct
29271 (Entrez Gene)
Cfl2
GeneProduct
366624 (Entrez Gene)
Chrm1
GeneProduct
25229 (Entrez Gene)
Chrm2
GeneProduct
81645 (Entrez Gene)
Chrm3
GeneProduct
24260 (Entrez Gene)
Chrm4
GeneProduct
25111 (Entrez Gene)
Chrm5
GeneProduct
53949 (Entrez Gene)
Crk
GeneProduct
54245 (Entrez Gene)
Csk
GeneProduct
315707 (Entrez Gene)
DIAP1
GeneProduct
DIAP3
GeneProduct
Dock1
GeneProduct
309081 (Entrez Gene)
Egf
GeneProduct
25313 (Entrez Gene)
Egfr
GeneProduct
24329 (Entrez Gene)
Enah
GeneProduct
360891 (Entrez Gene)
Ezr
GeneProduct
54319 (Entrez Gene)
F2
GeneProduct
29251 (Entrez Gene)
F2r
GeneProduct
25439 (Entrez Gene)
FGF18
GeneProduct
29369 (Entrez Gene)
Fgd1
GeneProduct
363460 (Entrez Gene)
Fgf10
GeneProduct
25443 (Entrez Gene)
Fgf11
GeneProduct
170632 (Entrez Gene)
Fgf12
GeneProduct
170630 (Entrez Gene)
Fgf1
GeneProduct
25317 (Entrez Gene)
Fgf13
GeneProduct
84488 (Entrez Gene)
Fgf14
GeneProduct
63851 (Entrez Gene)
Fgf15
GeneProduct
170582 (Entrez Gene)
Fgf16
GeneProduct
60464 (Entrez Gene)
Fgf17
GeneProduct
29368 (Entrez Gene)
Fgf20
GeneProduct
66017 (Entrez Gene)
Fgf21
GeneProduct
170580 (Entrez Gene)
Fgf22
GeneProduct
170579 (Entrez Gene)
Fgf23
GeneProduct
170583 (Entrez Gene)
Fgf2
GeneProduct
54250 (Entrez Gene)
Fgf3
GeneProduct
170633 (Entrez Gene)
Fgf4
GeneProduct
116499 (Entrez Gene)
Fgf5
GeneProduct
60662 (Entrez Gene)
Fgf6
GeneProduct
170700 (Entrez Gene)
Fgf7
GeneProduct
29348 (Entrez Gene)
Fgf8
GeneProduct
29349 (Entrez Gene)
Fgf9
GeneProduct
25444 (Entrez Gene)
Fgfr1
GeneProduct
79114 (Entrez Gene)
Fgfr2
GeneProduct
25022 (Entrez Gene)
Fgfr3
GeneProduct
84489 (Entrez Gene)
Fgfr4
GeneProduct
25114 (Entrez Gene)
Fn1
GeneProduct
25661 (Entrez Gene)
Git1
GeneProduct
83709 (Entrez Gene)
Gna12
GeneProduct
81663 (Entrez Gene)
Gna13
GeneProduct
303634 (Entrez Gene)
Gng12
GeneProduct
114120 (Entrez Gene)
Grlf1
GeneProduct
306400 (Entrez Gene)
Gsn
GeneProduct
296654 (Entrez Gene)
Ins1
GeneProduct
24505 (Entrez Gene)
Ins2
GeneProduct
24506 (Entrez Gene)
Iqgap1
GeneProduct
361598 (Entrez Gene)
Itga1
GeneProduct
25118 (Entrez Gene)
Kras
GeneProduct
24525 (Entrez Gene)
LOC442775
GeneProduct
LPS
Metabolite
C00338 (Kegg Compound)
Limk1
GeneProduct
65172 (Entrez Gene)
Map2k1
GeneProduct
170851 (Entrez Gene)
Map2k2
GeneProduct
58960 (Entrez Gene)
Mapk1
GeneProduct
116590 (Entrez Gene)
Mapk3
GeneProduct
50689 (Entrez Gene)
Mapk4
GeneProduct
54268 (Entrez Gene)
Mapk6
GeneProduct
58840 (Entrez Gene)
Mos
GeneProduct
24559 (Entrez Gene)
Mras
GeneProduct
25482 (Entrez Gene)
Msn
GeneProduct
81521 (Entrez Gene)
Myh10
GeneProduct
79433 (Entrez Gene)
Myl1
GeneProduct
56781 (Entrez Gene)
Myl3
GeneProduct
24585 (Entrez Gene)
Mylk
GeneProduct
288057 (Entrez Gene)
Nckap1
GeneProduct
58823 (Entrez Gene)
Nras
GeneProduct
24605 (Entrez Gene)
PIK3CA
GeneProduct
170911 (Entrez Gene)
PIP2
Metabolite
C04637 (Kegg Compound)
PIP3
Metabolite
C05981 (Kegg Compound)
PIP5K1A
GeneProduct
365865 (Entrez Gene)
PIP5KL1
GeneProduct
Pak1
GeneProduct
29431 (Entrez Gene)
Pak2
GeneProduct
29432 (Entrez Gene)
Pak3
GeneProduct
29433 (Entrez Gene)
Pak4
GeneProduct
292756 (Entrez Gene)
Pak6
GeneProduct
296078 (Entrez Gene)
Pak7
GeneProduct
311450 (Entrez Gene)
Pdgfa
GeneProduct
25266 (Entrez Gene)
Pdgfb
GeneProduct
24628 (Entrez Gene)
Pdgfra
GeneProduct
25267 (Entrez Gene)
Pdgfrb
GeneProduct
24629 (Entrez Gene)
Pfn1
GeneProduct
64303 (Entrez Gene)
Pik3c2a
GeneProduct
361632 (Entrez Gene)
Pik3c2b
GeneProduct
289021 (Entrez Gene)
Pik3c2g
GeneProduct
116720 (Entrez Gene)
Pik3c3
GeneProduct
65052 (Entrez Gene)
Pik3cb
GeneProduct
85243 (Entrez Gene)
Pik3cd
GeneProduct
366508 (Entrez Gene)
Pik3cg
GeneProduct
298947 (Entrez Gene)
Pik3r1
GeneProduct
25513 (Entrez Gene)
Pik3r2
GeneProduct
29741 (Entrez Gene)
Pik3r3
GeneProduct
60664 (Entrez Gene)
Pik3r4
GeneProduct
363131 (Entrez Gene)
Pik3r5
GeneProduct
497931 (Entrez Gene)
Pip4k2a
GeneProduct
116723 (Entrez Gene)
Pip4k2b
GeneProduct
89812 (Entrez Gene)
Pip4k2c
GeneProduct
140607 (Entrez Gene)
Pip5k1b
GeneProduct
309419 (Entrez Gene)
Pip5k1c
GeneProduct
314641 (Entrez Gene)
Ppp1r12a
GeneProduct
116670 (Entrez Gene)
Ptk2
GeneProduct
25614 (Entrez Gene)
Pxn
GeneProduct
360820 (Entrez Gene)
RAC1P4
GeneProduct
RAC3
GeneProduct
Rac1
GeneProduct
363875 (Entrez Gene)
Rac2
GeneProduct
366957 (Entrez Gene)
Raf1
GeneProduct
24703 (Entrez Gene)
Rassf7
GeneProduct
293623 (Entrez Gene)
Rdx
GeneProduct
315655 (Entrez Gene)
Rhoa
GeneProduct
117273 (Entrez Gene)
Rock1
GeneProduct
81762 (Entrez Gene)
Rock2
GeneProduct
25537 (Entrez Gene)
Rras2
GeneProduct
365355 (Entrez Gene)
Rras
GeneProduct
361568 (Entrez Gene)
SOS2
GeneProduct
85384 (Entrez Gene)
Slc9a1
GeneProduct
24782 (Entrez Gene)
Sos1
GeneProduct
313845 (Entrez Gene)
Ssh1
GeneProduct
304580 (Entrez Gene)
Ssh2
GeneProduct
303342 (Entrez Gene)
Ssh3
GeneProduct
365396 (Entrez Gene)
TMSB4X
GeneProduct
81814 (Entrez Gene)
Vav1
GeneProduct
25156 (Entrez Gene)
Vcl
GeneProduct
305679 (Entrez Gene)
Vil1
GeneProduct
316521 (Entrez Gene)
WAS
GeneProduct
317371 (Entrez Gene)
Wasf1
GeneProduct
294568 (Entrez Gene)
Wasf2
GeneProduct
313024 (Entrez Gene)
c3orf10
GeneProduct
Annotated Interactions
No annotated interactions
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External references
DataNodes
Annotated Interactions
No annotated interactions