Glyoxylate cycle (Mycobacterium tuberculosis)

Revision as of 15:57, 10 September 2013 by Andra (Talk | contribs)

Description

No description

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Bharadwaj VP, Katoch VM, Sharma VD, Kannan KB, Datta AK, Shivannavar CT; ''Metabolic studies on mycobacteria. IV. Assay of isocitrate lyase and malate synthase activity in M. leprae.''; Indian J Lepr, 1987 PubMed Europe PMC Scholia
Mu√±oz-El√≠as EJ, Upton AM, Cherian J, McKinney JD; ''Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence.''; Mol Microbiol, 2006 PubMed Europe PMC Scholia
Mu√±oz-El√≠as EJ, McKinney JD; ''Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence.''; Nat Med, 2005 PubMed Europe PMC Scholia
Wheeler PR, Ratledge C; ''Use of carbon sources for lipid biosynthesis in Mycobacterium leprae: a comparison with other pathogenic mycobacteria.''; J Gen Microbiol, 1988 PubMed Europe PMC Scholia
KORNBERG HL, KREBS HA; ''Synthesis of cell constituents from C2-units by a modified tricarboxylic acid cycle.''; Nature, 1957 PubMed Europe PMC Scholia
Seshadri R, Murthy PS, Venkitasubramanian TA; ''Isociatrate lyase in mycobacteria.''; Indian J Biochem Biophys, 1976 PubMed Europe PMC Scholia
McKinney JD, H√∂ner zu Bentrup K, Mu√±oz-El√≠as EJ, Miczak A, Chen B, Chan WT, Swenson D, Sacchettini JC, Jacobs WR Jr, Russell DG; ''Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase.''; Nature, 2000 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
97588	view	08:24, 28 May 2018	Fehrhart	updated outdated uniprot ID for MLS
89931	view	13:42, 6 October 2016	Mkutmon	Modified description
77539	view	19:52, 23 September 2014	Khanspers	Ontology Term : 'glyoxylate and dicarboxylate metabolic pathway' added !
77538	view	19:47, 23 September 2014	Khanspers	connected interactions
71840	view	19:46, 18 October 2013	MaintBot	Updated UniProt/TrEMBL data source
70854	view	10:23, 12 September 2013	Andra	Specify description
70849	view	08:59, 12 September 2013	Mkutmon	circular structure
70841	view	17:29, 11 September 2013	Andra	Modified description
70840	view	17:09, 11 September 2013	Andra	Added MLS and ICL references
70839	view	17:06, 11 September 2013	Andra	Periodical save, work in progress
70836	view	22:41, 10 September 2013	Andra	Specify description
70834	view	17:24, 10 September 2013	Andra	Made it more circular
70831	view	16:30, 10 September 2013	Andra	first draft
70830	view	16:28, 10 September 2013	Andra	Periodical save, work in progress
70829	view	16:18, 10 September 2013	Andra	Periodical save, work in progress
70828	view	16:08, 10 September 2013	Andra	Periodical save, work in progress
70827	view	15:57, 10 September 2013	Andra	Periodical save, work in progress
70826	view	15:25, 10 September 2013	Andra	work in progress
70825	view	15:14, 10 September 2013	Andra	Periodical save, work in progress
70821	view	12:49, 10 September 2013	Andra	Added source reference
70820	view	12:48, 10 September 2013	Andra	First Draft
70819	view	12:47, 10 September 2013	Andra	New pathway

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Name	Type	Database reference
Acetyl-CoA	Metabolite	392413 (Chemspider)
Citrate	Metabolite	29081 (Chemspider)
Fumarate	Metabolite	4573886 (Chemspider)
Glyoxylate	Metabolite	2849615 (Chemspider)
Isocitrate lyase isoform 1	GeneProduct	P0A5H3 (Uniprot/TrEMBL)
Isocitrate lyase isoform 2	GeneProduct
Isocitrate	Metabolite	4573809 (Chemspider)
MLS	GeneProduct	P0A5J4 (Uniprot/TrEMBL)
Malate	Metabolite	140981 (Chemspider)
Oxaloacetate	Metabolite	2509917 (Chemspider)
Succinate	Metabolite	140973 (Chemspider)

No annotated interactions