Prostaglandin synthesis and regulation (Canis familiaris)
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Cortisone
prolactin
release
Cell Membrane
Phospholipids
Inactive Metabolites
Cytoplasm
Gq signaling
pathway
PG Synthases
SCGB1A1
EDNRA
TBXAS1
EDN1
PGF2a
PTGDR
HSD11B2
ANXA2
S100A10
PGI2
PTGIS
HPGD
PTGDS
TXA2
S100A6
Arachidonic Acid
PLA2G4A
PTGS1
ANXA3
Cortisol
LOC478365
PGE2
PTGER1
Calcium
ANXA5
Prostaglandin H2
EDNRB
ANXA6
PTGFR
PGF2a
ANXA1
Calcium
PRL
ANXA8
PTGER2
HSD11B1
Progesterone
PTGER4
ANXA4
Cortisol
PTGIR
PTGS2
PTGER3
Description
No description
Comments
GenMAPP notes
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks
See note for more details
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP98(r20887)
with a 80% conversion rate.
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Quality Tags
Ontology Terms
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Bibliography
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History
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Compare
Revision
Action
Time
User
Comment
118056
view
10:36, 24 May 2021
Eweitz
Modified title
106037
view
11:56, 16 August 2019
MaintBot
HMDB identifier normalization
87601
view
08:53, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin biosynthetic pathway' added !
87600
view
08:53, 25 July 2016
Lindarieswijk
Ontology Term : 'prostaglandin signaling pathway' added !
71459
view
19:17, 17 October 2013
MaintBot
Automated update of data sources
68524
view
22:08, 5 July 2013
MaintBot
Updated to 2013 gpml schema
40678
view
21:49, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33968
view
18:27, 9 December 2009
MaintBot
Automatic update of empty xrefs
32549
view
13:05, 17 August 2009
MaintBot
Fixed text labels
32231
view
12:49, 15 August 2009
MaintBot
Fixed text labels
31737
view
11:59, 14 August 2009
MaintBot
Fixed group labels
31247
view
19:50, 13 August 2009
MaintBot
Fixed text labels
30680
view
22:43, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ANXA1
GeneProduct
476322 (Entrez Gene)
ANXA2
GeneProduct
403435 (Entrez Gene)
ANXA3
GeneProduct
478447 (Entrez Gene)
ANXA4
GeneProduct
606756 (Entrez Gene)
ANXA5
GeneProduct
476094 (Entrez Gene)
ANXA6
GeneProduct
479325 (Entrez Gene)
ANXA8
GeneProduct
Arachidonic Acid
Metabolite
Calcium
Metabolite
HMDB00464 (HMDB)
Cortisol
Metabolite
EDN1
GeneProduct
403424 (Entrez Gene)
PMID: 1474344
EDNRA
GeneProduct
450187 (Entrez Gene)
EDNRB
GeneProduct
403862 (Entrez Gene)
HPGD
GeneProduct
486073 (Entrez Gene)
HSD11B1
GeneProduct
449023 (Entrez Gene)
HSD11B2
GeneProduct
489758 (Entrez Gene)
LOC478365
GeneProduct
478365 (Entrez Gene)
PGE2
Metabolite
HMDB03175 (HMDB)
PGF2a
Metabolite
HMDB01139 (HMDB)
PGI2
Metabolite
HMDB01335 (HMDB)
PLA2G4A
GeneProduct
480048 (Entrez Gene)
PRL
GeneProduct
488241 (Entrez Gene)
PTGDR
GeneProduct
610845 (Entrez Gene)
PTGDS
GeneProduct
403740 (Entrez Gene)
PTGER1
GeneProduct
610774 (Entrez Gene)
PTGER2
GeneProduct
403797 (Entrez Gene)
PTGER3
GeneProduct
403430 (Entrez Gene)
PTGER4
GeneProduct
403589 (Entrez Gene)
PTGFR
GeneProduct
479981 (Entrez Gene)
PTGIR
GeneProduct
484429 (Entrez Gene)
PTGIS
GeneProduct
485919 (Entrez Gene)
PTGS1
GeneProduct
403544 (Entrez Gene)
PTGS2
GeneProduct
442942 (Entrez Gene)
Progesterone
Metabolite
Prostaglandin H2
Metabolite
S100A10
GeneProduct
475851 (Entrez Gene)
PMID: 12962548 relationship with Annexin 2
S100A6
GeneProduct
480143 (Entrez Gene)
SCGB1A1
GeneProduct
476060 (Entrez Gene)
PMID: 7615804, PMID: 3292559
TBXAS1
GeneProduct
482771 (Entrez Gene)
TXA2
Metabolite
HMDB01452 (HMDB)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Annotated Interactions
No annotated interactions