Nanoparticle-mediated activation of receptor signaling (Homo sapiens)

Revision as of 10:55, 3 April 2014 by Bart Smeets (Talk | contribs)

Description

No description

View approved pathways at the new wikipathways.org.

Review changes for Approved

Community: Adverse Outcome Pathways

Pathway Ontology : signaling pathway nanomaterial response pathway

Rauch J, Kolch W, Laurent S, Mahmoudi M; ''Big signals from small particles: regulation of cell signaling pathways by nanoparticles.''; Chem Rev, 2013 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
137818 Approved	view	06:42, 8 March 2025	Egonw	Modified description
136676	view	13:51, 19 February 2025	Eweitz	Adjust per PathVisio / Kaavio graphical discrepancy
136675	view	13:49, 19 February 2025	Eweitz	Use standard metabolite color, economize layout
123429 AOP	view	06:39, 26 July 2022	Egonw	Typed six data nodes
110709	view	14:36, 28 May 2020	Laurent	Added missing DataNode type - changed IDs to WikiPathways IDs
106660	view	21:19, 12 September 2019	Khanspers	Modified description
105661	view	05:17, 10 August 2019	Khanspers	Modified description
102132	view	09:12, 2 December 2018	Egonw	Replaced Wikipedia with Wikidata identifiers.
95473	view	08:43, 16 December 2017	Egonw	Oh, there were two nodes :(
95472	view	08:42, 16 December 2017	Egonw	Replace a Wikipedia ID with the matching Wikidata ID (with more mappings).
92317	view	08:50, 20 May 2017	Egonw	Ontology Term : 'nanomaterial response pathway' added !
87898	view	12:53, 25 July 2016	Elisa	Ontology Term : 'signaling pathway' added !
74251	view	08:45, 11 April 2014	Elisa	Using label type for text elements
74250	view	08:40, 11 April 2014	Elisa	Using label type for text elements
74187	view	11:00, 3 April 2014	Bart Smeets	Modified title
74186	view	11:00, 3 April 2014	Bart Smeets	Modified description
74185	view	10:56, 3 April 2014	Bart Smeets	Modified description
74184	view	10:55, 3 April 2014	Bart Smeets	Modified description
74183	view	10:55, 3 April 2014	Bart Smeets	New pathway

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Name	Type	Database reference
AKT	Protein	Q9Y243 (Uniprot-TrEMBL)
Amphiregulin	Protein	P15514 (Uniprot-TrEMBL)
Angiogenesis		Angiogenesis (Wikipedia)
Apoptosis		Apoptosis (Wikipedia)
Autocrine loop
Collagen	Protein	P02452 (Uniprot-TrEMBL)
Differentiation		Cellular differentiation (Wikipedia)
EGFR	Protein	P00533 (Uniprot-TrEMBL)
Endocytosis of NP
FAK	Protein	Q05397 (Uniprot-TrEMBL)
Fibronectin	Protein	P02751 (Uniprot-TrEMBL)
Grb	Protein	P62993 (Uniprot-TrEMBL)
HRAS	Protein	P01112 (Uniprot-TrEMBL)
Inflammation		Inflammation (Wikipedia)
Integrin
JNK1	Protein	P45983 (Uniprot-TrEMBL)
JNK2	Protein	P45984 (Uniprot-TrEMBL)
JNK3	Protein	P53779 (Uniprot-TrEMBL)
KRAS	Protein	P01116 (Uniprot-TrEMBL)
MAP2K1	Protein	Q02750 (Uniprot-TrEMBL)
MAP2K2	Protein	P36507 (Uniprot-TrEMBL)
MAPK11	Protein	Q15759 (Uniprot-TrEMBL)
MAPK12	Protein	P53778 (Uniprot-TrEMBL)
MAPK13	Protein	O15264 (Uniprot-TrEMBL)
MAPK14	Protein	Q16539 (Uniprot-TrEMBL)
MAPK1	Protein	P28482 (Uniprot-TrEMBL)
Migration		Cell migration (Wikipedia)
NP-induced extracellular ROS production
NRAS	Protein	P01111 (Uniprot-TrEMBL)
PI3K	Protein	O00329 (Uniprot-TrEMBL)
Paxillin	Protein	P49023 (Uniprot-TrEMBL)
Proliferation		Cell proliferation (Wikipedia)
RAF	Protein	P04049 (Uniprot-TrEMBL)
ROS		Reactive oxygen species (Wikipedia)
Receptor-mediated NP uptake
Sos	Protein	Q07889 (Uniprot-TrEMBL)
Src	Protein	P12931 (Uniprot-TrEMBL)
Talin	Protein	Q9Y490 (Uniprot-TrEMBL)
α	Protein	P56199 (Uniprot-TrEMBL)
β	Protein	P05556 (Uniprot-TrEMBL)

No annotated interactions