Principal pathways of carbon metabolism (Saccharomyces cerevisiae)

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GluconeogenesisCytoplasmOther Pathways of Carbon MetabolismMitochondrionGlycolysis[NOTE: TKL1, TKL2, Glyceraldehyde-3-phosphate,Fructose-6-phosphate, and Xylulose-5-phosphateare duplicated for clarity, but are part of thesame cytoplasmic pool.]Transport between Cytoplasm and MitochondrionPhosphoenolpyruvate6-PhosphogluconateMDH2PFK1Glyceraldehyde-3-phosphatePCK1Glycerol 3-phosphateSOL4Ribulose-5-phosphateEthanol2-PhosphoglycerateFructose 1,6-bisphosphateTDH1MalateADH3 (mt)ADH4 (mt)3-PhosphoglycerateAcetateAcetaldehydePGK1TDH2Xylulose-5-phosphateTPI1Glyceraldehyde-3-phosphatePGI1Erythrose-4-phosphateGPD2FBA1CDC19RHR2GlycerolDihydroxyacetoneFructose-6-phosphatePDC6GlucoseGPM1PYC2PDC1D-6-Phospho-glucono-delta-lactoneSedoheptulose-7-phosphateHOR2GUT2Xylulose-5-phosphateTDH3Acetyl-CoAZWF1EthanolPYK2PyruvateGLK11,3-BisphosphoglycerateGlucose-6-phosphatePYC1AcetaldehydeACS1 (mt)TKL1GND2AcetateGPD1MDH3ADH2HXK1ENO1ACS2RPE1TKL2TKL2GND1FBP1TKL1PhosphatePFK2TAL1OxaloacetateADH1GUT1ALD4 (mt)ALD6SOL3Ribose-5-PhosphatePDC5ENO2HXK2Fructose-6-phosphateADH5RKI1CIT3SDH4LPD1IsocitrateCIT1FumarateSDH3SDH2IDP1MalateSDH1Glyoxylatealpha-ketoglutarateLSC1SuccinateAcetyl-CoAMDH1Succinyl-CoALSC2IDH2LPD1CitrateFUM1IDP2PDX1ACO2LAT1PDB1MAE1CIT2PDA1DAL7KGD2KGD1IDH1ICL1MLS1ACO1PyruvateOxaloacetateAcetyl-CoA


Description

Based on Glycolysis and Gluconeogenesis Pathways at SGD and on Kruckeberg, AL and Dickinson, JR (2004) Carbon Metabolism in The Metabolism and Molecular Physiology of Saccharomyces cerevisiae, Dickinson, JR and Schweizer, M, eds, CRC Press.

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Quality Tags

Ontology Terms

 

Bibliography

  1. ARTHUR L. KRUCKEBERG, J. RICHARD DICKINSON; ''Metabolism and Molecular Physiology of Saccharomyces Cerevisiae''; https://doi.org/10.1201/9780203503867, 2004 DOI Scholia

History

View all...
CompareRevisionActionTimeUserComment
135334view20:19, 23 August 2024Khanspersupdated lit ref
135039view10:48, 1 August 2024EgonwCopied a reference to the references section
134397view19:47, 21 July 2024EweitzRemove template comments
134272view06:54, 19 July 2024EgonwMarked several interactions as mim-translocations
117329view11:49, 20 May 2021EweitzModified title
114358view19:30, 8 January 2021DeSlUpdated duplicate ID for glucose from cas to wikidata
107010view13:46, 17 September 2019MaintBotHMDB identifier normalization
102415view09:53, 23 December 2018EgonwReplaced a deleted CAS number with the active one.
94660view11:30, 4 October 2017DeSlConnected unconnected lines, changed ribose-5-phosphate to D-ribose-5-phosphate.
92228view13:56, 13 May 2017EgonwFixed the ID for Glyceraldehyde-3-phosphate.
78138view01:03, 5 December 2014AlexanderPicoUpdated cycle and reaction layout
76272view20:25, 25 June 2014Khanspersupdated layout, connected lines, added metabolites
76271view18:34, 25 June 2014Khanspersremoved genmapp notes
76270view18:21, 25 June 2014KhanspersModified description
69647view20:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
67604view11:32, 26 June 2013DdiglesOntology Term : 'lipid hormone signaling pathway' added !
58989view19:35, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
56498view11:53, 8 January 2013EgonwMarked many more metabolites as such with DataNode@Type
56497view11:46, 8 January 2013EgonwEthanol is a metabolite
41886view04:52, 2 March 2011MaintBotRemoved redundant pathway information and comments
29883view11:10, 9 June 2009Thomasupdated ensembl references
20919view11:30, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Principle Carbon Metabolism]] moved to [[Pathway:WP112]]: Moved to stable identifier
12822view08:04, 17 May 2008MaintBotautomated metabolite conversion
10998view20:22, 2 March 2008MaintBotyeast id converter
8891view14:11, 7 January 2008MaintBotAdded to category $category
8889view14:11, 7 January 2008KdahlquistUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,3-BisphosphoglycerateMetabolite1981-49-3 (CAS)
2-PhosphoglycerateMetabolite2553-59-5 (CAS)
3-PhosphoglycerateMetabolite820-11-1 (CAS)
6-PhosphogluconateMetabolite921-62-0 (CAS)
ACO1GeneProductYLR304C (Ensembl)
ACO2GeneProductYJL200C (Ensembl)
ACS1 (mt)GeneProductYAL054C (Ensembl)
ACS2GeneProductYLR153C (Ensembl)
ADH1GeneProductYOL086C (Ensembl)
ADH2GeneProductYMR303C (Ensembl)
ADH3 (mt)GeneProductYMR083W (Ensembl)
ADH4 (mt)GeneProductYGL256W (Ensembl)
ADH5GeneProductYBR145W (Ensembl)
ALD4 (mt)GeneProductYOR374W (Ensembl)
ALD6GeneProductYPL061W (Ensembl)
AcetaldehydeMetabolite75-07-0 (CAS)
AcetateMetabolite64-19-7 (CAS)
Acetyl-CoAMetabolite72-89-9 (CAS)
CDC19GeneProductYAL038W (Ensembl)
CIT1GeneProductYNR001C (Ensembl)
CIT2GeneProductYCR005C (Ensembl)
CIT3GeneProductYPR001W (Ensembl)
CitrateMetabolite29081 (Chemspider)
D-6-Phospho-glucono-delta-lactoneMetabolite90-80-2 (CAS)
DAL7GeneProductYIR031C (Ensembl)
DihydroxyacetoneMetabolite96-26-4 (CAS)
ENO1GeneProductYGR254W (Ensembl)
ENO2GeneProductYHR174W (Ensembl)
Erythrose-4-phosphateMetabolite585-18-2 (CAS)
EthanolMetabolite64-17-5 (CAS)
FBA1GeneProductYKL060C (Ensembl)
FBP1GeneProductYLR377C (Ensembl)
FUM1GeneProductYPL262W (Ensembl)
Fructose 1,6-bisphosphateMetabolite488-69-7 (CAS)
Fructose-6-phosphateMetabolite643-13-0 (CAS)
FumarateMetaboliteHMDB00134 (HMDB)
GLK1GeneProductYCL040W (Ensembl)
GND1GeneProductYHR183W (Ensembl)
GND2GeneProductYGR256W (Ensembl)
GPD1GeneProductYDL022W (Ensembl)
GPD2GeneProductYOL059W (Ensembl)
GPM1GeneProductYKL152C (Ensembl)
GUT1GeneProductYHL032C (Ensembl)
GUT2GeneProductYIL155C (Ensembl)
Glucose-6-phosphateMetabolite59-56-3 (CAS)
GlucoseMetabolite50-99-7 (CAS)
Glyceraldehyde- 3-phosphateMetabolite56-82-6 (CAS)
Glyceraldehyde-3-phosphateMetabolite591-57-1 (CAS)
Glycerol 3-phosphateMetabolite57-03-4 (CAS)
GlycerolMetabolite56-81-5 (CAS)
GlyoxylateMetaboliteHMDB00119 (HMDB)
HOR2GeneProductYER062C (Ensembl)
HXK1GeneProductYFR053C (Ensembl)
HXK2GeneProductYGL253W (Ensembl)
ICL1GeneProductYER065C (Ensembl)
  • peroxisome
  • Type your comment here
IDH1GeneProductYNL037C (Ensembl)
IDH2GeneProductYOR136W (Ensembl)
IDP1GeneProductYDL066W (Ensembl)
IDP2GeneProductYLR174W (Ensembl)
IsocitrateMetabolite320-77-4 (CAS)
KGD1GeneProductYIL125W (Ensembl)
KGD2GeneProductYDR148C (Ensembl)
LAT1GeneProductYNL071W (Ensembl)
LPD1GeneProductYFL018C (Ensembl)
LSC1GeneProductYOR142W (Ensembl)
LSC2GeneProductYGR244C (Ensembl)
MAE1GeneProductYKL029C (Ensembl)
MDH1GeneProductYKL085W (Ensembl)
MDH2GeneProductYOL126C (Ensembl)
MDH3GeneProductYDL078C (Ensembl)
MLS1GeneProductYNL117W (Ensembl)
  • peroxisome
  • Type your comment here
MalateMetabolite617-48-1 (CAS)
OxaloacetateMetabolite328-42-7 (CAS)
OxaloacetateMetaboliteHMDB00223 (HMDB)
PCK1GeneProductYKR097W (Ensembl)
PDA1GeneProductYER178W (Ensembl)
PDB1GeneProductYBR221C (Ensembl)
PDC1GeneProductYLR044C (Ensembl)
PDC5GeneProductYLR134W (Ensembl)
PDC6GeneProductYGR087C (Ensembl)
PDX1GeneProductYGR193C (Ensembl)
PFK1GeneProductYGR240C (Ensembl)
PFK2GeneProductYMR205C (Ensembl)
PGI1GeneProductYBR196C (Ensembl)
PGK1GeneProductYCR012W (Ensembl)
PYC1GeneProductYGL062W (Ensembl)
PYC2GeneProductYBR218C (Ensembl)
PYK2GeneProductYOR347C (Ensembl)
PhosphateMetabolite14265-44-2 (CAS)
PhosphoenolpyruvateMetabolite138-08-9 (CAS)
PyruvateMetabolite127-17-3 (CAS)
PyruvateMetaboliteHMDB00243 (HMDB)
RHR2GeneProductYIL053W (Ensembl)
RKI1GeneProductYOR095C (Ensembl)
RPE1GeneProductYJL121C (Ensembl)
Ribose-5-PhosphateMetabolite3615-55-2 (CAS)
Ribulose-5-phosphateMetabolite4151-19-3 (CAS)
SDH1GeneProductYKL148C (Ensembl)
SDH2GeneProductYLL041C (Ensembl)
SDH3GeneProductYKL141W (Ensembl)
SDH4GeneProductYDR178W (Ensembl)
SOL3GeneProductYHR163W (Ensembl)
SOL4GeneProductYGR248W (Ensembl)
Sedoheptulose-7-phosphateMetabolite2646-35-7 (CAS)
SuccinateMetaboliteHMDB00254 (HMDB)
Succinyl-CoAMetabolite604-98-8 (CAS)
TAL1GeneProductYLR354C (Ensembl)
TDH1GeneProductYJL052W (Ensembl)
TDH2GeneProductYJR009C (Ensembl)
TDH3GeneProductYGR192C (Ensembl)
TKL1GeneProductYPR074C (Ensembl)
TKL2GeneProductYBR117C (Ensembl)
TPI1GeneProductYDR050C (Ensembl)
Xylulose-5-phosphateMetabolite60802-29-1 (CAS)
ZWF1GeneProductYNL241C (Ensembl)
alpha-ketoglutarateMetaboliteHMDB00208 (HMDB)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP112"
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