Role of lipid metabolism (Caenorhabditis elegans)

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1, 2KeyInhibitsWell fed animalsFat storage1LPD-3CCO-1/LPD-4ATPUnfolded protein response (UPR)LPD-6LPD-51111SIR-2.1/SIR2.12LPD-9MAC-11LPD-81LPD-711SBP-12CBP-1HSP-422ATGL-1PhosphorylatedAAK-22PAR-42KRI-122lips-72DAF-16CTBP-122DAF-22Proposed to inhibitProposed to stimulateStimulatesDAF-162lipl-42DAF-16 translocation to nucleus2Starvationfil-12lips-72Conditional stimulationIRE-12Dauer animalsPhosphorylation ofAAK-22AAK-22RegulatesPhosphorylatesLIFESPANPositivelyinfluencesNegatively influences


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. McKay RM, McKay JP, Avery L, Graff JM; ''C elegans: a model for exploring the genetics of fat storage.''; Dev Cell, 2003 PubMed Europe PMC Scholia
  2. Elle IC, Olsen LC, Pultz D, Rødkaer SV, Faergeman NJ; ''Something worth dyeing for: molecular tools for the dissection of lipid metabolism in Caenorhabditis elegans.''; FEBS Lett, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118329view12:56, 27 May 2021UlasBabayigitturned arrows in legend and lip-4/7 and fil-1 transcription arrows into graphical lines
116501view10:37, 7 May 2021EweitzModified title
107083view14:17, 17 September 2019MaintBotChEBI identifier normalization
87643view08:54, 25 July 2016LindarieswijkOntology Term : 'lipid metabolic pathway' added !
79936view17:42, 27 April 2015Kyookadded WP2578 to UPR node
79874view23:52, 22 April 2015KyookModified description
79873view23:48, 22 April 2015KyookNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AAK-2GeneProductT01C8.1 (WormBase)
ATGL-1GeneProductWBGene00015484 (WormBase)
ATPMetabolite15422 (ChEBI)
CBP-1GeneProductR10E11.1 (WormBase)
CCO-1/LPD-4GeneProductF26E4.9 (WormBase)
CTBP-1GeneProductF49E10.5 (WormBase)
DAF-16

translocation

to nucleus		GeneProductR13H8.1 (WormBase)
DAF-16GeneProductR13H8.1 (WormBase)
DAF-2GeneProductY55D5A.5 (WormBase)
HSP-4GeneProductF43E2.8 (WormBase)
IRE-1GeneProductC41C4.4 (WormBase)
KRI-1GeneProductZK265.1 (WormBase)
LIFESPAN
LPD-3GeneProductY47G6A.23 (WormBase)
LPD-5GeneProductZK973.10 (WormBase)
LPD-6GeneProductK09H9.6 (WormBase)
LPD-7GeneProductR13A5.12 (WormBase)
LPD-8GeneProductR10H10.1 (WormBase)
LPD-9GeneProductT21C9.5 (WormBase)
MAC-1GeneProductY48C3A.7 (WormBase)
PAR-4GeneProductY59A8B.14 (WormBase)
Phosphorylated AAK-2GeneProductT01C8.1 (WormBase)
Phosphorylation of AAK-2GeneProductR13H8.1 (WormBase)
SBP-1GeneProductY47D3B.7 (WormBase)
SIR-2.1/SIR2.1GeneProductR11A8.4 (WormBase)
Unfolded protein response (UPR)
fil-1GeneProductT01C3.4 (WormBase)
lipl-4GeneProductK04A8.5 (WormBase)
lips-7GeneProductC09E8.2 (WormBase)

Annotated Interactions

No annotated interactions

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