Central carbon metabolism (Escherichia coli)
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1
2-OG
Ace
GOX
PEP
T3P
ICT
FUM
CIT
F6P
Ace-CoA
G6P
P5P
FBP
SUC
SUC-CoA
OAA
MAL
6PG
PYR
Glucose
Galactose
Description
No description
Comments
The pathway was drawn from Figure 1 in the paper.
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Bibliography
Haverkorn van Rijsewijk BR, Nanchen A, Nallet S, Kleijn RJ, Sauer U; ''Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli.''; Mol Syst Biol, 2011
PubMed
Europe PMC
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Action
Time
User
Comment
117433
view
10:50, 21 May 2021
Eweitz
Modified title
89169
view
03:42, 23 August 2016
Ariutta
Ontology Term : 'classic metabolic pathway' added !
83523
view
08:34, 20 November 2015
Anwesha
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
2-OG
Metabolite
C00026 (KEGG Compound)
6PG
Metabolite
C00345 (KEGG Compound)
Ace-CoA
Metabolite
C00024 (KEGG Compound)
Ace
Metabolite
C00033 (KEGG Compound)
CIT
Metabolite
C00158 (KEGG Compound)
F6P
Metabolite
C05345 (KEGG Compound)
FBP
Metabolite
C05378 (KEGG Compound)
FUM
Metabolite
C00122 (KEGG Compound)
G6P
Metabolite
C00668 (KEGG Compound)
GOX
Metabolite
Galactose
Metabolite
C00124 (KEGG Compound)
Glucose
Metabolite
C00221 (KEGG Compound)
ICT
Metabolite
C00311 (KEGG Compound)
MAL
Metabolite
C00149 (KEGG Compound)
OAA
Metabolite
C00036 (KEGG Compound)
P5P
Metabolite
PEP
Metabolite
C00074 (KEGG Compound)
PYR
Metabolite
C00022 (KEGG Compound)
SUC-CoA
Metabolite
C00091 (KEGG Compound)
SUC
Metabolite
C00042 (KEGG Compound)
T3P
Metabolite
C00197 (KEGG Compound)
Annotated Interactions
View all...
Source
Target
Type
Database reference
Comment
2-OG
SUC-CoA
Arrow
R01197 (KEGG Reaction)
6PG
Arrow
WpR4 (WikiPathways)
6PG
P5P
Arrow
WpR11 (WikiPathways)
Ace-CoA
Ace
Arrow
R00227 (KEGG Reaction)
Ace-CoA
R00351 (KEGG Reaction)
Ace-CoA
WpR12 (WikiPathways)
Arrow
WpR13 (WikiPathways)
Arrow
WpR4 (WikiPathways)
CIT
ICT
Arrow
WpR2 (WikiPathways)
R01325 : Citrate <=> cis-Aconitate + H2O
R01900 : Isocitrate <=> cis-Aconitate + H2O
F6P
FBP
Arrow
WpR6 (WikiPathways)
FBP
T3P
Arrow
WpR5 (WikiPathways)
FUM
MAL
Arrow
R01082 (KEGG Reaction)
G6P
6PG
Arrow
WpR3 (WikiPathways)
R02035 : D-Glucono-1,5-lactone 6-phosphate + H2O <=> 6-Phospho-D-gluconate
R02736 : beta-D-Glucose 6-phosphate + NADP+ <=> D-Glucono-1,5-lactone 6-phosphate + NADPH + H+
G6P
F6P
Arrow
R03321 (KEGG Reaction)
GOX
MAL
Arrow
WpR12 (WikiPathways)
Galactose
G6P
Arrow
WpR7 (WikiPathways)
Glucose
G6P
Arrow
R01600 (KEGG Reaction)
ICT
2-OG
Arrow
R00709 (KEGG Reaction)
ICT
GOX
Arrow
WpR13 (WikiPathways)
MAL
OAA
Arrow
R00361 (KEGG Reaction)
MAL
PYR
Arrow
WpR9 (WikiPathways)
OAA
Arrow
WpR10 (WikiPathways)
OAA
CIT
Arrow
R00352 (KEGG Reaction)
PEP
Arrow
R00431 (KEGG Reaction)
PEP
PYR
Arrow
WpR8 (WikiPathways)
PYR
Ace-CoA
Arrow
R00209 (KEGG Reaction)
SUC-CoA
SUC
Arrow
R00432 (KEGG Reaction)
SUC
FUM
Arrow
R02164 (KEGG Reaction)
T3P
PEP
Arrow
WpR1 (WikiPathways)
R00658 : 2-Phospho-D-glycerate <=> Phosphoenolpyruvate + H2O
R01518 : 2-Phospho-D-glycerate <=> 3-Phospho-D-glycerate
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