Flavonoid pathway (Arabidopsis thaliana)

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1CatalystCatalystKaempferol 7-neohesperidoside7-Hydroxy-3',4'-dimethoxyflavoneQuercetin 3,7-dirhamnosideRXN-14844'-MethylluteolinCatalystKaempferolQuercetin 3-O-glucoside-7-O-rhamnosideCyanidin 3-sambubioside-5-glucosideCyanidin2,7,4'-Trihydroxyiso- flavanoneBiochanin A 7-glucosideCyanidin 3-(6-p-coumaroylglucoside)AcacetinCyanidin 3,5-di-O-glucosideGenkwanin7,3',4'-TrihydroxyflavoneApigenin 7,4'-dimethyl etherCatalystIsorhamnetin 3-arabinosideCinnamtannin A1Kaempferol 3-rhamnoside-7-glucosideCatalystMedicarpinCyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-glucosideCatalyst6,7,4'-TrihydroxyflavanoneProcyanidin B2Isovitexin6-MethoxyluteolinCatalystCyanidine 3-sambubiosideKaempferol 3-glucoside-(1->6)-glucoside-7-alpha-L-rhamnosideQuercetin 3,7-diglucoside7,4'-Dihydroxy-6-methoxyisoflavone, GlyciteinHomoeriodictyolCatalyst6-HydroxydaidzeinPruninNaringenin 4'- O-glucosideProductScutellarein 7-glucuronideCatalystCyanidin 3-sophorosideCyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucosideQuercetin 3-rhamnoside-7-glucoside(+)-epicatechin2'-HydroxyformononetinKaempferol 3,7-di-O-rhamnosideCatalystIsoliquiritigeninQuercetin 3-neohesperidosideRXN-525DIHYDROKAEMPFEROL- 4-REDUCTASE-RXNCatalystScutellareinNaringenin chalconeAfzelechinLiquiritin2,6,7,4'-TetrahydroxyisoflavanoneIsorhamnetin 3-neohesperidosideDiosmetin 7-rutinosideLuteolin 7-glucosideCatalyst3-O-MethylquercetinApigenin 7-rutinosideCatalystCatalystCatalystKaempferol 3-neohesperidosidePopulninCyanidin 3-glucosideCatalystKaempferol 3-galactoside-7-rhamnosideNaringinPuerarincatechinCatalystQuercetinCatalystCyanidin 3-(6''-p-coumaryl-2'''-sinapylsambubioside)-5-(6-malonylglucoside)Hirsutrin, Quercetin 3-GlucosideApigeninKaempferol 3-O-rhamninosideDihydrokaempferolKaempferol 3-robinoside (K 3-(6''-RhaGal))Isorhamnetin 3-O-rutinoside8C-Glucosyl-2,7,4'- trihydroxyisoflavanoneRXN-7652Daidzein 7-glucosideIsorhamnetin 3,7-dirhamnosideCatalystCyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-glucosideLeucopelargonidinIsorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranosideCatalystHesperidinAstragalinPelargonidinHesperetindihydroquercetin, TaxifolinDiosmetin 7-glucosideNARINGENIN-3- DIOXYGENASE-RXNCatalystIsorhamnetin 3-O-beta-D-glucopyranosideQuercetin 3-O-alpha-L-arabinopyranosideCatalystEpiafzelechinIsorhamnetin 3-alpha-L-arabinopyranoside-7-rhamnosideCatalystCatalystFormononetin5,7-DimethoxyapigeninRXN-1481Luteolin 5,7-diglucosideTilirosideepicatechin heptamerCatalyst2',4',5,7-Tetrahydroxy- isoflavanoneCosmosiinCatalystKaempferol 3,7-diglucosideCyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) glucoside] 5-O-glucosideKaempferol 3-glucoside-7-rhamnosideKaempferol 3-neohesperidoside-7-rhamnosideQuercetin 3-neohesperidoside-7-rhamnosideLeucocyanidinLuteolin 4',7-diglucosideKaempferol 3-gentiobiosideKaempferol 3-galactosideGenistinKaempferol 3-alpha-L-arabinofuranoside-7-rhamnosidePrunetinCyanidin 3-(6-p-coumaroylsambubioside)p-Coumaroyl-CoACyanidin 3-(6-p-coumaroylglucoside)-5-(6-malonylglucoside)Isorhamnetin 3-rhamnoside-7-glucosideCatalystAfzelinLuteolin 3',7-diglucosideEriodictyolCyanidin 3-O-[2''-O-(xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-[6'''-O-(malonyl) glucoside]RXN-7775RXN-97247,4'-Dihydroxyflavone7,4'-Dihydroxy-3'-methoxyflavoneQuercetin 3-Arabinoside-7-rhamnosideLEUCOPEL-RXNNaringeninCyanidin 3-O-[2-O-(2-O-(sinapoyl)-bata-D-xylopyranosyl) 6-O-(4-O-(beta-D-glucopyranosyl)-p-coumaroyl-bata-D-glucopyranoside] 5-O-[6-O-(malonyl) bata-D-glucopyranoside]Cyanidin 3-(6''-(E)-p-coumarylsambubioside)-5-glucosideGenistein6C-Glucosyl-2- hydroxynaringeninVestitoneKaempferol 3-arabinosideIsorhamnetinFormononetin 7-GlucosideCatalystCyanidin 3-(6-p-coumaroylglucoside)-5-glucosideCatalystQuercetin 7-glucosideCatalystLiquiritigeninQuercetin 3-O-L-rhamnoside2-HydroxynaringeninDiosmetin 7-neohesperidosideIsorhamnetin 3-neohesperidoside-7-rhamnosideHesperetin 7-glucosideProcyanidin C1Luteolin 4'-glucoside[Epicatechin-(4beta->8)]4-epicatechinHesperetin 7-neohesperidosideRXN-527DaidzeinQuercetin 3-rutinoside-7-rhamnosideKaempferol 3-O-rutinosideLuteolinBiochanin ASaponarinCatalystIsorhamnetin 3-rhamnosideEpicatechin-(4beta->8)5-epicatechin7,2'-Dihydroxy-4'-methoxy-isoflavanolCyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-glucosideCatalystCatalyst6-HydroxluteolinCyanidin 3-O-[2''-O-(xylosyl) glucoside] 5-O-(6'''-O-malonyl) glucosideCatalystRutin,Birutan7,3'-Dihydroxy-4'-methoxyflavone2


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Bibliography

  1. Saito K, Yonekura-Sakakibara K, Nakabayashi R, Higashi Y, Yamazaki M, Tohge T, Fernie AR; ''The flavonoid biosynthetic pathway in Arabidopsis: structural and genetic diversity.''; Plant Physiol Biochem, 2013 PubMed Europe PMC Scholia
  2. Brazier-Hicks M, Evans KM, Gershater MC, Puschmann H, Steel PG, Edwards R; ''The C-glycosylation of flavonoids in cereals.''; J Biol Chem, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118336view13:14, 27 May 2021Mkutmonpublication ref
103424view11:59, 28 February 2019DeSlVertical allignment, moved reactions closer together for readability.
103423view11:46, 28 February 2019DeSlHorizontal layout
103422view11:34, 28 February 2019DeSlUpdated layout left hand side
103421view10:02, 28 February 2019DeSlChanged layout (righthand side and middle).
103027view08:25, 1 February 2019TokimatsuFix Annotations.
103026view07:31, 1 February 2019TokimatsuFix interactions, topology and labels.
102670view01:37, 17 January 2019TokimatsuFix interactions and labels.
102669view01:20, 17 January 2019TokimatsuFix interactions.
102644view08:49, 16 January 2019Tokimatsuremove reactions/metabolites undiscovered from Brassicaceae. Add reaction IDs.
102628view07:23, 15 January 2019Tokimatsuremove reactions/metabolites undiscovered from Brassicaceae
101938view04:31, 19 November 2018EgonwRemoved "undefined" as data source.
96270view07:16, 3 March 2018EgonwFixed the syntax of a KNApSAcK ID (too many zeros).
95486view10:25, 18 December 2017DeSlChanged all arrows to MIM-type conversion.
95484view10:01, 18 December 2017DeSlConnected unconnected line
95445view07:27, 15 December 2017Kozo2add rhea annotation
92987view18:09, 21 July 2017Khanspersconnected interaction
92901view09:46, 15 July 2017EgonwModified description
87496view01:43, 25 July 2016AlexanderPicoOntology Term : 'classic metabolic pathway' added !
87495view01:43, 25 July 2016AlexanderPicoOntology Term : 'flavonoid biosynthetic pathway' added !
87428view12:10, 22 July 2016Kozo2replace Kaempferol ID from KNApSAcK to PubChem-compound
87330view11:42, 21 July 2016Kozo2test direct xml editing
87319view00:24, 21 July 2016AlexanderPicoupdated ID for Cyanidin
87251view10:45, 20 July 2016Kozo2Quick edit to datanode annotation or property
86212view18:16, 6 July 2016Kozo2Quick edit to datanode annotation or property
86211view17:44, 6 July 2016Kozo2Quick edit to datanode annotation or property
86210view17:34, 6 July 2016Kozo2Quick edit to datanode annotation or property
86007view07:57, 24 June 2016Kozo2Quick edit to datanode annotation or property
84960view19:00, 3 April 2016Kozo2confirm the feasibility of updating ID mappings from local pathvisio bridge
84959view17:46, 3 April 2016Kozo2replace non-KNApSAcK IDs to KNApSAcK
84958view16:42, 3 April 2016Kozo2replace non-KNApSAcK IDs to KNApSAcK
84957view15:55, 3 April 2016Kozo2assign KNApSAcK IDs to Apigenin derivative
84956view15:27, 3 April 2016Kozo2assign KNApSAcK IDs to Liquiritigenin derivative
84955view13:44, 3 April 2016Kozo2assign KNApSAcK IDs to Genistein derivative
84954view13:04, 3 April 2016Kozo2assign KNApSAcK IDs to Eriodictyol derivative
84953view11:08, 3 April 2016Kozo2assign KNApSAcK IDs to Luteolin derivative
84950view05:24, 3 April 2016Kozo2assign KNApSAcK IDs to Cyanidine derivative
84947view17:11, 2 April 2016Kozo2assign KNApSAcK IDs to Isorhamnetin derivative
84944view04:30, 2 April 2016Kozo2assign KNApSAcK IDs to Quercetin derivative
84943view03:55, 2 April 2016Kozo2assign KNApSAcK IDs to Kaempferol derivative
84942view03:38, 2 April 2016Kozo2assign KNApSAcK IDs to Kaempferol derivative
84890view01:48, 31 March 2016Kozo2assign KNApSAcK IDs to the compounds under Isoliquiritigenin
84889view23:50, 30 March 2016Kozo2Quick edit to datanode annotation or property
84888view23:49, 30 March 2016Kozo2assign KNApSAcK IDs to catechins
84872view08:34, 29 March 2016Kozo2Test updating KNApSAcK ID from PathVisio
84831view14:12, 24 March 2016Kozo2Quick edit to datanode annotation or property
84830view13:28, 24 March 2016Kozo2Quick edit to datanode annotation or property
84829view12:49, 24 March 2016Kozo2Quick edit to datanode annotation or property
84827view10:16, 24 March 2016Kozo2Quick edit to datanode annotation or property
84781view09:52, 20 March 2016EgonwChanged the data source from a metabolite to PubChem-compound.

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(+)-epicatechinMetaboliteC00000956 (KNApSAcK)
2',4',5,7-Tetrahydroxy- isoflavanoneMetabolite102056-04-2 (CAS)
2'-HydroxyformononetinMetaboliteC00000257 (KNApSAcK)
2,6,7,4'-TetrahydroxyisoflavanoneMetabolite
2,7,4'-Trihydroxyiso- flavanoneMetaboliteC15567 (KEGG Compound)
2-HydroxynaringeninMetabolite58124-18-8 (CAS)
3-O-MethylquercetinMetabolite
4'-MethylluteolinMetabolite
5,7-DimethoxyapigeninMetabolite
6,7,4'-TrihydroxyflavanoneMetabolite
6-HydroxluteolinMetabolite
6-HydroxydaidzeinMetaboliteC00009385 (KNApSAcK)
6-MethoxyluteolinMetabolite
6C-Glucosyl-2- hydroxynaringeninMetabolite90657396 (PubChem-compound)
7,2'-Dihydroxy-4'-methoxy-isoflavanolMetabolite
7,3',4'-TrihydroxyflavoneMetaboliteC00003825 (KNApSAcK)
7,3'-Dihydroxy-4'-methoxyflavoneMetaboliteC00013297 (KNApSAcK)
7,4'-Dihydroxy-3'-methoxyflavoneMetaboliteC00003826 (KNApSAcK)
7,4'-Dihydroxy-6-methoxyisoflavone, GlyciteinMetaboliteC00009392 (KNApSAcK)
7,4'-DihydroxyflavoneMetaboliteC12123 (KEGG Compound)
7-Hydroxy-3',4'-dimethoxyflavoneMetaboliteC00013298 (KNApSAcK)
8C-Glucosyl-2,7,4'- trihydroxyisoflavanoneMetabolite
AcacetinMetabolite
AfzelechinMetabolite2545-00-8 (CAS)
AfzelinMetaboliteC00005140 (KNApSAcK)
Apigenin 7,4'-dimethyl etherMetabolite
Apigenin 7-rutinosideMetabolite
ApigeninMetabolite520-36-5 (CAS)
AstragalinMetaboliteC00005138 (KNApSAcK)
Biochanin AMetabolite
Biochanin A 7-glucosideMetabolite
CatalystGeneProduct
CatalystPathwayR02442 (SWISS-MODEL)
CatalystPathwayR06556 (SWISS-MODEL)
CatalystPathwayR06793 (SWISS-MODEL)
CatalystPathwayR07317 (SWISS-MODEL)
CatalystGeneProduct
Cinnamtannin A1MetaboliteC00009107 (KNApSAcK)
CosmosiinMetabolite
Cyanidin 3,5-di-O-glucosideMetabolite
Cyanidin 3-(6''-(E)-p-coumarylsambubioside)-5-glucosideMetabolite
Cyanidin 3-(6''-p-coumaryl-2'''-sinapylsambubioside)-5-(6-malonylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)-5-(6-malonylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)-5-glucosideMetabolite
Cyanidin 3-(6-p-coumaroylsambubioside)Metabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-[6'''-O-(malonyl) glucoside]Metabolite
Cyanidin 3-O-[2''-O-(xylosyl) glucoside] 5-O-(6'''-O-malonyl) glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucosideMetabolite
Cyanidin 3-O-[2-O-(2-O-(sinapoyl)-bata-D-xylopyranosyl) 6-O-(4-O-(beta-D-glucopyranosyl)-p-coumaroyl-bata-D-glucopyranoside] 5-O-[6-O-(malonyl) bata-D-glucopyranoside]Metabolite
Cyanidin 3-glucosideMetabolite
Cyanidin 3-sambubioside-5-glucosideMetabolite
Cyanidin 3-sophorosideMetabolite
CyanidinMetaboliteC00006614 (KNApSAcK)
Cyanidine 3-sambubiosideMetaboliteundefined (undefined)
DIHYDROKAEMPFEROL- 4-REDUCTASE-RXNDIHYDROKAEMPFEROL-4-REDUCTASE-RXN (HGNC)
Daidzein 7-glucosideMetaboliteC00002518 (KNApSAcK)
DaidzeinMetaboliteC10208 (KEGG Compound)
DihydrokaempferolMetaboliteC00974 (KEGG Compound)
Diosmetin 7-glucosideMetabolite
Diosmetin 7-neohesperidosideMetabolite
Diosmetin 7-rutinosideMetabolite
EpiafzelechinMetaboliteC00008805 (KNApSAcK)
Epicatechin-(4beta->8)5-epicatechinMetaboliteC00002918 (KNApSAcK)
EriodictyolMetabolite552-58-9 (CAS)
Formononetin 7-GlucosideMetaboliteC00002553 (KNApSAcK)
FormononetinMetaboliteC00002525 (KNApSAcK)
GenisteinMetaboliteC06563 (KEGG Compound)
GenistinMetabolite
GenkwaninMetabolite
HesperetinMetabolite
Hesperetin 7-glucosideMetabolite
Hesperetin 7-neohesperidosideMetabolite
HesperidinMetabolite
Hirsutrin, Quercetin 3-GlucosideMetabolite
HomoeriodictyolMetabolite
IsoliquiritigeninMetaboliteC08650 (KEGG Compound)
IsorhamnetinMetabolite
Isorhamnetin 3,7-dirhamnosideMetabolite
Isorhamnetin 3-O-beta-D-glucopyranosideMetabolite
Isorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranosideMetabolite
Isorhamnetin 3-O-rutinosideMetabolite
Isorhamnetin 3-alpha-L-arabinopyranoside-7-rhamnosideMetabolite
Isorhamnetin 3-arabinosideMetabolite
Isorhamnetin 3-neohesperidosideMetabolite
Isorhamnetin 3-neohesperidoside-7-rhamnosideMetabolite
Isorhamnetin 3-rhamnosideMetabolite
Isorhamnetin 3-rhamnoside-7-glucosideMetabolite
IsovitexinMetaboliteC00001059 (KNApSAcK)
Kaempferol 3,7-di-O-rhamnosideMetaboliteC00005189 (KNApSAcK)
Kaempferol 3,7-diglucosideMetaboliteC00005182 (KNApSAcK)
Kaempferol 3-O-rhamninosideMetaboliteC00005202 (KNApSAcK)
Kaempferol 3-O-rutinosideMetaboliteC00005169 (KNApSAcK)
Kaempferol 3-alpha-L-arabinofuranoside-7-rhamnosideMetaboliteC00005174 (KNApSAcK)
Kaempferol 3-arabinosideMetaboliteC00005132 (KNApSAcK)
Kaempferol 3-galactoside-7-rhamnosideMetaboliteC00005178 (KNApSAcK)
Kaempferol 3-galactosideMetaboliteC00005137 (KNApSAcK)
Kaempferol 3-gentiobiosideMetaboliteC00005166 (KNApSAcK)
Kaempferol 3-glucoside-(1->6)-glucoside-7-alpha-L-rhamnosideMetaboliteC00005234 (KNApSAcK)
Kaempferol 3-glucoside-7-rhamnosideMetabolite
Kaempferol 3-neohesperidoside-7-rhamnosideMetabolite
Kaempferol 3-neohesperidosideMetaboliteC00005167 (KNApSAcK)
Kaempferol 3-rhamnoside-7-glucosideMetaboliteC00005188 (KNApSAcK)
Kaempferol 3-robinoside (K 3-(6''-RhaGal))MetaboliteC00005160 (KNApSAcK)
Kaempferol 7-neohesperidosideMetaboliteC00005197 (KNApSAcK)
KaempferolMetaboliteC00004565 (KNApSAcK)
LEUCOPEL-RXNLEUCOPEL-RXN (HGNC)
LeucocyanidinMetabolite
LeucopelargonidinMetabolite520-17-2 (CAS)
LiquiritigeninMetaboliteC00000977 (KNApSAcK)
LiquiritinMetaboliteC00008193 (KNApSAcK)
Luteolin 3',7-diglucosideMetabolite
Luteolin 4',7-diglucosideMetabolite
Luteolin 4'-glucosideMetabolite
Luteolin 5,7-diglucosideMetabolite
Luteolin 7-glucosideMetabolite
LuteolinMetaboliteC01514 (KEGG Compound)
MedicarpinMetaboliteC00002547 (KNApSAcK)
NARINGENIN-3- DIOXYGENASE-RXNNARINGENIN-3-DIOXYGENASE-RXN (HGNC)
Naringenin 4'- O-glucosideMetabolite81202-36-0 (CAS)
Naringenin chalconeMetaboliteundefined (undefined)
NaringeninMetaboliteC00509 (KEGG Compound)
NaringinMetabolite
PelargonidinMetaboliteC05904 (KEGG Compound)
PopulninMetaboliteC00005149 (KNApSAcK)
Procyanidin B2MetaboliteC00009077 (KNApSAcK)
Procyanidin C1MetaboliteC00009098 (KNApSAcK)
ProductScutellarein 7-glucuronideMetabolite
PrunetinMetaboliteundefined (SWISS-MODEL)
PruninMetabolite
PuerarinMetaboliteC10524 (KEGG Compound)
QuercetinMetabolite
Quercetin 3,7-diglucosideMetabolite
Quercetin 3,7-dirhamnosideMetabolite
Quercetin 3-Arabinoside-7-rhamnosideMetabolite
Quercetin 3-O-L-rhamnosideMetabolite
Quercetin 3-O-alpha-L-arabinopyranosideMetabolite
Quercetin 3-O-glucoside-7-O-rhamnosideMetabolite
Quercetin 3-neohesperidosideMetabolite
Quercetin 3-neohesperidoside-7-rhamnosideMetabolite
Quercetin 3-rhamnoside-7-glucosideMetabolite
Quercetin 3-rutinoside-7-rhamnosideMetabolite
Quercetin 7-glucosideMetabolite
RXN-1481RXN-1481 (STRING)
RXN-1484RXN-1484 (STRING)
RXN-525RXN-525 (HGNC)
RXN-527RXN-527 (HGNC)
RXN-7652RXN-7652 (STRING)
RXN-7775RXN-7775 (STRING)
RXN-9724RXN-9724 (STRING)
Rutin,BirutanMetabolite
SaponarinMetaboliteC08064 (KEGG Compound)
ScutellareinMetaboliteC10184 (KEGG Compound)
TilirosideMetaboliteC00005851 (KNApSAcK)
VestitoneMetaboliteC00002584 (KNApSAcK)
[Epicatechin-(4beta->8)]4-epicatechinMetaboliteC00009109 (KNApSAcK)
catechinMetaboliteC06562 (KEGG Compound)
dihydroquercetin, TaxifolinMetaboliteC01617 (KEGG Compound)
epicatechin heptamerMetabolite
p-Coumaroyl-CoAMetaboliteundefined (undefined)

Annotated Interactions

SourceTargetTypeDatabase referenceComment
6C-Glucosyl-2- hydroxynaringeninIsovitexinArrowRXN-14076 (BioCyc)
NaringeninNaringenin 4'- O-glucosideArrowR08006 (KEGG Reaction)
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