Humoral immune response to fungal and bacterial pathogens (Drosophila melanogaster)
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Description
Pathways regulating Drosophila's humoral response to bacterial and fungal pathogens. Pathogens such as fungal B-1-3-glucans and virulence factors illicit signalling pathways through receptors on body fat cells of Drosophila Melanogaster (Protein Toll, PGRP-LC, and Domeless). The activation of receptors initiates pathways that increase transcription of antimicrobial agents and thioester proteins.
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Bibliography
- Igboin CO, Griffen AL, Leys EJ; ''The Drosophila melanogaster host model.''; J Oral Microbiol, 2012 PubMed Europe PMC Scholia
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