Tgif disruption of Shh signaling (Homo sapiens)

Revision as of 12:48, 1 July 2016 by AAR&Co (Talk | contribs)

Description

No description

View approved pathways at the new wikipathways.org.

Open Access

Review changes for Approved

Pathway Ontology : disease pathway neurological disorder pathway

Disease : traumatic neurosis spinal cord disease

Cell Type : astrocyte of the spinal cord monocyte microglial cell T cell B cell motor neuron spinal cord motor neuron macrophage oligodendrocyte neutrophil

Taniguchi K, Anderson AE, Sutherland AE, Wotton D; ''Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.''; PLoS Genet, 2012 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
117841 Approved	view	15:13, 22 May 2021	Eweitz	Modified description
113712	view	14:06, 18 November 2020	DeSl	Removed Krzeszinski paper from GPML
113711	view	14:04, 18 November 2020	DeSl	Removed Krzeszinski publication and info thereof, since the paper has been retracted.
103865	view	22:02, 11 April 2019	AlexanderPico	Ontology Term : 'skeletogenic cell' added !
103864	view	22:02, 11 April 2019	AlexanderPico	Ontology Term : 'genetic disease' added !
103863	view	21:59, 11 April 2019	AlexanderPico	added ref
103862	view	21:57, 11 April 2019	AlexanderPico	added mir; updated description; reorganized; red inhibitions
88772	view	19:37, 14 August 2016	AAR&Co	Modified description
88771	view	19:35, 14 August 2016	AAR&Co	Ontology Term : 'altered Hedgehog signaling pathway' added !
88769	view	19:34, 14 August 2016	AAR&Co	Modified description
87049	view	23:03, 17 July 2016	AlexanderPico	Ontology Term : 'signaling pathway' added !
87048	view	23:01, 17 July 2016	AlexanderPico	Reduced white space
87047	view	23:00, 17 July 2016	AlexanderPico	Periodical save, work in progress
86152	view	10:57, 2 July 2016	Egonw	Replaced a mim-conversion with Arrow.
86128	view	12:59, 1 July 2016	AAR&Co	Modified description
86127	view	12:48, 1 July 2016	AAR&Co	New pathway

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Name	Type	Database reference
FGF8	GeneProduct	ENSG00000107831 (Ensembl)
FOXG1	GeneProduct	ENSG00000176165 (Ensembl)
GLI3	GeneProduct	ENSG00000106571 (Ensembl)
NKX2-1	GeneProduct	ENSG00000136352 (Ensembl)
NODAL	GeneProduct	ENSG00000156574 (Ensembl)
SHH	GeneProduct	ENSG00000164690 (Ensembl)
SMAD2	GeneProduct	ENSG00000175387 (Ensembl)
TGIF1	GeneProduct	ENSG00000177426 (Ensembl)
TGIF2	GeneProduct	ENSG00000118707 (Ensembl)

No annotated interactions