TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Sancisi V, Gandolfi G, Ragazzi M, Nicoli D, Tamagnini I, Piana S, Ciarrocchi A; ''Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway.''; PLoS One, 2013 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	137179	view	08:25, 28 February 2025	Egonw	Made a pathway clickable
	137137	view	23:13, 27 February 2025	Khanspers	Modified description
	128360	view	21:32, 2 February 2024	Ash iyer	Added protein complex oject and added pathway identifier for SMAD pathway
	128349	view	06:46, 2 February 2024	Khanspers	specified gene product node xrefs, layout, clarification
	117840	view	15:13, 22 May 2021	Eweitz	Modified title
	117837	view	15:11, 22 May 2021	Eweitz	Modified title
	106478	view	19:42, 3 September 2019	Khanspers	Modified description
	105460	view	05:09, 8 August 2019	Khanspers	Modified description
	90120	view	00:17, 14 October 2016	Khanspers	updated layout and interactions
	89942	view	13:56, 6 October 2016	Egonw	Modified description
	88619	view	02:02, 12 August 2016	AAR&Co	Added Data Nodes
	88618	view	02:01, 12 August 2016	AAR&Co	Periodical save, work in progress
	87420	view	11:32, 22 July 2016	Mkutmon	Ontology Term : 'signaling pathway' added !
	87310	view	21:17, 20 July 2016	AAR&Co	Modified description
	87306	view	20:51, 20 July 2016	AAR&Co	Ontology Term : 'thyroid cancer' added !
	87305	view	20:48, 20 July 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
AKT	GeneProduct	ENSG00000142208 (Ensembl)	AKT Not Specified
CDH16	GeneProduct	ENSG00000166589 (Ensembl)
CDH6	GeneProduct	ENSG00000113361 (Ensembl)
E-CAD	GeneProduct	6753374 (NCBI Protein)
ERK	GeneProduct	495678 (NCBI Protein)
FN1	GeneProduct	ENSG00000115414 (Ensembl)
ID1	GeneProduct	ENSG00000125968 (Ensembl)
MAPK	GeneProduct	ENSG00000100030 (Ensembl)	MAPK Not Specified
N-CAD	Protein	A0A024RC42 (Uniprot-TrEMBL)
PI3K	GeneProduct	54792082 (NCBI Protein)
RUNX2	GeneProduct	ENSG00000124813 (Ensembl)
SMAD2	GeneProduct	ENSG00000175387 (Ensembl)
SMAD3	GeneProduct	ENSG00000166949 (Ensembl)
SMAD4	GeneProduct	ENSG00000141646 (Ensembl)
SNAI1	GeneProduct	ENSG00000124216 (Ensembl)
SNAI2	GeneProduct	ENSG00000019549 (Ensembl)
TGF-B	GeneProduct	425148 (NCBI Protein)
TNC	GeneProduct	ENSG00000041982 (Ensembl)
VIM	GeneProduct	ENSG00000026025 (Ensembl)

Annotated Interactions

No annotated interactions