S1P receptor signal transduction (Canis familiaris)
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Lindarieswijk
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GPCRs similar to S1P
S1PR2
MAPK3
GNAI3
GNAI1
S1PR3
MAPK1
PLCB2
AKT2
GNAI2
S1PR1
ASAH1
PLCB3
MAPK6
SPHK1
PLCB1
MAPK4
LOC51190
MAPK12
RACGAP1
PIK3C2B
S1PR5
AKT3
MAPK7
SPHK2
AKT1
Description
No description
Comments
GenMAPP notes
Representation of Figure 2. from T. Hla, et al. 2001, Science, 294, pg. 1877
GenMAPP remarks
Right click here for reference.
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP26(r20731)
with a 96% conversion rate.
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Bibliography
Hla T, Lee MJ, Ancellin N, Paik JH, Kluk MJ; ''Lysophospholipids--receptor revelations.''; Science, 2001
PubMed
Europe PMC
Scholia
History
View all...
Compare
Revision
Action
Time
User
Comment
118659
view
15:18, 31 May 2021
DeSl
Ontology Term : 'signaling pathway' added !
118658
view
15:18, 31 May 2021
DeSl
Ontology Term : 'G protein mediated signaling pathway' added !
118657
view
15:17, 31 May 2021
DeSl
Connected last unconnected line
118656
view
15:16, 31 May 2021
DeSl
Added description from WP26
118655
view
15:15, 31 May 2021
DeSl
Cleaned up comments in description
118654
view
15:14, 31 May 2021
DeSl
Converted top complex to group, according to lit. ref.
118653
view
15:12, 31 May 2021
DeSl
Updated title according to WP26
118652
view
15:12, 31 May 2021
DeSl
Redrawn, structured, converted complexes to groups, as in original (WP26)
87662
view
08:55, 25 July 2016
Lindarieswijk
Ontology Term : 'sphingosine 1-phosphate signaling pathway' added !
68536
view
22:21, 5 July 2013
MaintBot
Updated to 2013 gpml schema
40692
view
21:50, 1 March 2011
MaintBot
Removed redundant pathway information and comments
31808
view
12:20, 14 August 2009
MaintBot
Fixed group labels
30767
view
23:14, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AKT1
GeneProduct
490878 (Entrez Gene)
AKT2
GeneProduct
449021 (Entrez Gene)
AKT3
GeneProduct
442964 (Entrez Gene)
ASAH1
GeneProduct
482897 (Entrez Gene)
GNAI1
GeneProduct
478227 (Entrez Gene)
GNAI2
GeneProduct
442957 (Entrez Gene)
GNAI3
GeneProduct
611810 (Entrez Gene)
LOC51190
GeneProduct
MAPK12
GeneProduct
607023 (Entrez Gene)
MAPK1
GeneProduct
477575 (Entrez Gene)
MAPK3
GeneProduct
486758 (Entrez Gene)
MAPK4
GeneProduct
491690 (Entrez Gene)
MAPK6
GeneProduct
478311 (Entrez Gene)
MAPK7
GeneProduct
489532 (Entrez Gene)
PIK3C2B
GeneProduct
478938 (Entrez Gene)
PLCB1
GeneProduct
485773 (Entrez Gene)
PLCB2
GeneProduct
487491 (Entrez Gene)
PLCB3
GeneProduct
476034 (Entrez Gene)
RACGAP1
GeneProduct
486549 (Entrez Gene)
S1PR1
GeneProduct
490138 (Entrez Gene)
S1PR2
GeneProduct
484959 (Entrez Gene)
S1PR3
GeneProduct
484199 (Entrez Gene)
S1PR5
GeneProduct
610828 (Entrez Gene)
SPHK1
GeneProduct
483329 (Entrez Gene)
SPHK2
GeneProduct
484401 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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DataNodes
Annotated Interactions
No annotated interactions