RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis (Homo sapiens)
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Description
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Ontology Terms
Bibliography
- Read RD, Fenton TR, Gomez GG, Wykosky J, Vandenberg SR, Babic I, Iwanami A, Yang H, Cavenee WK, Mischel PS, Furnari FB, Thomas JB; ''A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.''; PLoS Genet, 2013 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Akt1 | GeneProduct | FBgn0010379 (Ensembl) | AKT Not Specified |
Egfr | GeneProduct | FBgn0003731 (Ensembl) | |
Pi3K | GeneProduct | FBgn0015279 (Ensembl) | |
Pten | GeneProduct | FBgn0026379 (Ensembl) | |
RIOK1 | GeneProduct | FBgn0036187 (Ensembl) | |
RIOK2 | GeneProduct | FBgn0039306 (Ensembl) | |
TORC2 | GeneProduct | Q3U182 (Uniprot-TrEMBL) | |
Tumorogenesis | Pathway | Identifier Not Found | |
foxo | GeneProduct | FBgn0038197 (Ensembl) | |
p53 | GeneProduct | FBgn0039044 (Ensembl) |
Annotated Interactions
No annotated interactions