GPR40 pathway (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Pancreatic Beta cellEndoplasmic ReticulumFactin Remodelingenabling insulin exocytosisInsulin containing vesicleInsulin ExocytosisF-actin filamentsinositol-3-phosphateDAGIP3RCa2+PKD1Unknown target genesPLCG1PLCG2PLCE1PLCB1PLCB2PLCD1PLCZ1PLCB3PLCH1PLCL1PLCD3GPR40GNA11Name: GPR40 PATHWAYOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:MissingXref.pngAnnotate nodes
Image:Curated.pngReview changes for Approved
Image:Featured.pngReview changes for Featured

Ontology Terms

 

Bibliography

  1. Poitout V, Lin DC; ''Modulating GPR40: therapeutic promise and potential in diabetes''; , 2013 PubMed Europe PMC Scholia
  2. Mancini AD, Poitout V; ''The fatty acid receptor FFA1/GPR40 a decade later: how much do we know? Mancini AD1, Poitout V.''; , 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117148view09:42, 18 May 2021EweitzModified title
107154view14:24, 17 September 2019MaintBotChEBI identifier normalization
96485view16:36, 15 March 2018Fehrhartfixed connection
94758view15:41, 5 October 2017Mkutmonfix unconnected lines
91307view18:43, 26 January 2017KhanspersModified title
91076view20:35, 30 December 2016AlexanderPicoOntology Term : 'insulin secretion pathway' added !
91075view20:34, 30 December 2016AlexanderPicoOntology Term : 'G protein mediated signaling pathway' added !
91074view20:29, 30 December 2016AlexanderPicoManually fixed literature reference
91064view12:24, 29 December 2016EgonwSmall fix in one of the IDs.
91057view22:56, 27 December 2016SiddiqaOntology Term : 'signaling pathway' added !
91056view22:54, 27 December 2016SiddiqaModified description
91055view22:45, 27 December 2016SiddiqaNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
Ca2+Metabolite29108 (ChEBI)
DAGMetabolite18035 (ChEBI)
GNA11GeneProductENSG00000088256 (Ensembl)
GPR40GeneProductENSG00000126266 (Ensembl)
IP3RGeneProductENSG00000096433 (Ensembl)
PKD1GeneProductENSG00000008710 (Ensembl)
PLCB1GeneProductENSG00000182621 (Ensembl)
PLCB2GeneProductENSG00000137841 (Ensembl)
PLCB3GeneProductENSG00000149782 (Ensembl)
PLCD1GeneProductENSG00000187091 (Ensembl)
PLCD3GeneProductENSG00000161714 (Ensembl)
PLCE1GeneProductENSG00000138193 (Ensembl)
PLCG1GeneProductEnsembl:ENSG00000124181 (Ensembl)
PLCG2GeneProductENSG00000197943 (Ensembl)
PLCH1GeneProductENSG00000114805 (Ensembl)
PLCL1GeneProductENSG00000115896 (Ensembl)
PLCZ1GeneProductENSG00000139151 (Ensembl)
Unknown target genesGeneProduct
inositol-3-phosphateMetabolite16595 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3958"
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