Somatroph axis (GH) and its relationship to dietary restriction and aging (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none Dietary RestrictionAgingFOXOIGF-1PTENSIRT1PI3KGHMTORPGC-1 alphaAKTIGF and insuline signalingAMPKName: Somatroph axis (GH) and its relationship to dietary restriction and agingOrganism: Homo sapiens


Description

No description

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Quality Tags

Image:Unconnected.pngFix interactions
Image:Curated.pngReview changes for Approved
Image:PLoS_OpenAccess.pngOpen Access

Ontology Terms

Pathway Ontology : Wnt signaling pathway
 

Bibliography

  1. Lopez C, Blasco MA, Partridge L, Serrano M, Kroemer G; ''The hallmarks of aging.''; Cell, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
137495
Approved
view08:21, 3 March 2025EgonwModified description
135816view00:54, 12 November 2024EweitzFix typo
123455view05:06, 28 July 2022EgonwMade a pathway clickable
105819view23:01, 15 August 2019KhanspersModified description
95479view09:12, 18 December 2017AndraConnected unconnected line
95400view14:46, 12 December 2017DeSlChanged MIM conversion to MIM stimulation for protein-protein interactions.
95393view19:42, 11 December 2017DeSlChanged ID for AMPK, spelling correction for lit. reference.
95392view19:36, 11 December 2017DeSlModified description
95391view19:35, 11 December 2017DeSlAdded literature reference, changed colors.
95390view19:26, 11 December 2017DeSlOntology Term : 'growth factor signaling pathway' added !
95389view19:24, 11 December 2017DeSlOntology Term : 'aging pathway' added !
95388view11:31, 11 December 2017Rik LahaijeModified description
95387view11:26, 11 December 2017Rik LahaijeNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
AKTGeneProductENSG00000142208 (Ensembl)
AMPKMetaboliteCHEBI:85053 (ChEBI)
FOXOGeneProductENSG00000150907 (Ensembl)
GHMetaboliteCHEBI:37845 (ChEBI)
IGF and insuline signalingPathwayWP2799 (WikiPathways)
IGF-1GeneProductENSG00000140443 (Ensembl)
MTORGeneProductENSG00000198793 (Ensembl)
PGC-1 alphaProteinQ01711 (Uniprot-TrEMBL)
PI3K ProteinNP_006209.2 (NCBI Protein)
PTENProteinENSG00000171862 (Ensembl)
SIRT1GeneProductENSG00000096717 (Ensembl)

Annotated Interactions

No annotated interactions

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