Caloric restriction and aging (Homo sapiens)

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1(+) Stress resistance(+) Lifespan and healthspanAutophagyCaloric restrictionmTORNAMPTATPAMPKSIRT1insulin/IGF1AMPNAD (+)PGC-1aFOXOAKTp53MitochondrialbiogenisisOxidative stress


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G; ''The hallmarks of aging.''; Cell, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
106347view21:35, 21 August 2019KhanspersModified description
105548view06:10, 9 August 2019KhanspersModified description
96444view08:33, 15 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
95530view20:33, 20 December 2017EgonwModified description
95529view20:31, 20 December 2017EgonwFixed character encoding.
95505view14:17, 18 December 2017DeSlAdded IDs for metabolites.
95504view14:14, 18 December 2017DeSlOntology Term : 'autophagy pathway' added !
95503view14:13, 18 December 2017DeSlOntology Term : 'oxidative stress response pathway' added !
95502view14:12, 18 December 2017DeSlOntology Term : 'aging pathway' added !
95501view14:12, 18 December 2017DeSlModified description
95500view14:11, 18 December 2017DeSlNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKTGeneProductENSG00000142208 (Ensembl)
AMPMetabolite
AMPKGeneProductENSG00000131791 (Ensembl)
ATPMetabolite
FOXOGeneProductENSG00000214295 (Ensembl)
NAD (+)Metabolite
NAMPTGeneProductENSG00000105835 (Ensembl)
PGC-1aGeneProductENSG00000109819 (Ensembl)
SIRT1GeneProductENSG00000096717 (Ensembl)
insulin/IGF1GeneProductENSG00000017427 (Ensembl)
mTORGeneProductENSG00000198793 (Ensembl)
p53GeneProductENSG00000141510 (Ensembl)

Annotated Interactions

No annotated interactions

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