Phosphatidylcholine catabolism (Homo sapiens)

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1Receptor-mediated mitogen activityLands Cycle*Membrane transportsphingomyleinasesphosphocholinePC(18:0/20:4)PA-PLA1choline kinasePLA1ATPsphingomyelinAcyltransferaseStearoyl(18:0) CoAbetaineFFALyso-PCCholineKennedy pathwayLysoPLA1Acyl-CoAGlycerol 3-phosphateLyso-PC(/20:4)CoAPLDLyso-PA(/20:4)PDEACSFFA(18:0)acetylcholinecPLA2PA(18:0/20:4)Cell patterning and growthStress responseAAglycerol-phosphocholineLysoPLA2*Lands CycleADP


Description

Schematic representation of phosphatidylcholine catabolism. Formation of various metabolites formed from phosphatidylcholine catabolism, which are signaling molecules.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Gibellini F, Smith TK; ''The Kennedy pathway--De novo synthesis of phosphatidylethanolamine and phosphatidylcholine.''; IUBMB Life, 2010 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123457view05:06, 28 July 2022EgonwMade a pathway clickable
101838view16:47, 12 November 2018EgonwReplaced an old Uniprot data source with the new one.
98190view07:26, 3 August 2018EgonwReplaced the CAS number of a salt with a Wikidata of the parent compound.
98157view08:14, 31 July 2018EgonwReplaced the CAS number of a salt with a Wikidata of the parent compound.
96447view09:25, 15 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
95593view09:24, 4 January 2018DeSlChnaged layout
95592view09:22, 4 January 2018DeSlAdded last missing identifiers
95591view09:13, 4 January 2018DeSlOntology Term : 'phosphatidylcholine metabolic pathway' added !
95590view09:12, 4 January 2018DeSlOntology Term : 'phosphatidylcholine biosynthetic pathway' added !
95589view09:01, 4 January 2018DeSlAdded wikidata as database source where applicable
95588view08:59, 4 January 2018DeSlAdded more identifiers
95587view08:43, 4 January 2018DeSlAdded several identifiers, and information from text of article which was not in Figure 3
95586view14:25, 3 January 2018DeSlNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AAMetabolite
ACSProtein6.2.1.3 (Enzyme Nomenclature) acyl-CoA synthetase
ADPMetabolite
ATPMetabolite
Acyl-CoAMetabolite
AcyltransferaseProtein
CholineMetaboliteCHEBI:3665 (ChEBI)
CoAMetabolite
FFA(18:0)Metabolite
FFAMetaboliteCHEBI:35366 (ChEBI) Free fatty acids
Glycerol 3-phosphateMetaboliteQ26711901 (Wikidata)
Kennedy pathwayPathwayWP3933 (WikiPathways)
Lyso-PA(/20:4)Metabolite
Lyso-PCMetabolite
Lyso-PC(/20:4)Metabolite
LysoPLA1Protein3.1.1.5 (Enzyme Nomenclature) lysophospholipase
LysoPLA2*Protein3.1.1.5 (Enzyme Nomenclature) lysophospholipase
PA(18:0/20:4)Metabolitephosphatidic acid = PA
PA-PLA1Protein
PC(18:0/20:4)Metabolitephosphatidylcholine = PC
PDEProtein3.1.4 (Enzyme Nomenclature) a phosphodiesterase
PLA1Protein3.1.1.32 (Enzyme Nomenclature) phospholipase A1
PLDProtein3.1.4.4 (Enzyme Nomenclature) phospholipase D
Stearoyl(18:0) CoAMetabolite
acetylcholineMetaboliteQ180623 (Wikidata)
betaineMetaboliteQ10860583 (Wikidata)
cPLA2Protein3.1.1.4 (Enzyme Nomenclature) phospholipase A2
choline kinaseProtein
glycerol-phosphocholineMetaboliteQ28529699In Figure spelled as glycerophosphocholine, in text as glycerol-phosphocholine
phosphocholineMetaboliteCHEBI:295975 (ChEBI)
sphingomyelinMetaboliteCHEBI:17636 (ChEBI)
sphingomyleinasesProtein

Annotated Interactions

No annotated interactions

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