Biogenic amine synthesis (Danio rerio)

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1TyrosineGABADopamineGlutamateHistidineTryptophanSerotoninEpinephrinePhenylalanineL-DOPAHistamineSynthesis pathways for biogenic amines (in blue)follow solid arrows through enzymatic steps, while degradation steps follow the dashed arrows.NorepinephrineAcetylcholine5-hydroxy-tryptophanMelatoninAcetylserotoninCholineMAOADBHCHATPNMTaanat1MAOAddcCOMTHDCtph1zgc:112198achegad1ddcpahTHddcASMT


Description

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source: http://www.whatislife.com/reader2/Metabolism/pathway/Neurotransmitter.html

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Ontology Terms

 

Bibliography

  1. Purves, Dale, Augustine, George J., Fitzpatrick, David, Katz, Lawrence C., LaMantia, Anthony-Samuel, McNamara, James O., Williams, S. Mark.; ''Neuroscience''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=neurosci&part=A405, 2001

History

View all...
CompareRevisionActionTimeUserComment
137286view15:25, 1 March 2025EgonwThese are the L-forms
116851view10:47, 14 May 2021EweitzModified title
105102view12:32, 8 July 2019DeSlChanges wikidata ID for ASMT gene
96498view06:46, 16 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
96483view16:23, 15 March 2018DeSlOntology Term : 'dopamine degradation pathway' added !
96482view16:22, 15 March 2018DeSlTried to find other gene IDs, but not findable in bridgeDb for species
96478view16:09, 15 March 2018DeSlAdded wikidata as database source where applicable
96477view16:07, 15 March 2018DeSlAdded last IDs needed to annotate full PW.
96469view15:48, 15 March 2018DeSlModified description
96467view15:47, 15 March 2018DeSlAnnotated all metabolites.
96464view15:27, 15 March 2018DeSlRemoved "last modified" item
96463view15:26, 15 March 2018DeSlConnected enzymes to arrows, changed arrows to MIM-conversion, changed layout slightly.
89464view13:14, 15 September 2016Mkutmonremove space in ontology term id
77401view22:34, 5 September 2014MaintBotremoved homology mapp label
71530view19:23, 17 October 2013MaintBotAutomated update of data sources
70075view09:18, 12 July 2013Mkutmonfixed unconnected lines
67085view10:04, 26 June 2013Christine ChichesterOntology Term : 'biogenic amine biosynthetic pathway' added !
62806view19:20, 2 May 2013EgonwConverted many labels into Metabolite DataNodes.
62805view19:13, 2 May 2013EgonwConnected dots.
40837view22:18, 1 March 2011MaintBotRemoved redundant pathway information and comments
35161view14:39, 11 February 2010ThomasModified description
35160view14:39, 11 February 2010Thomasadded literature
34220view21:34, 9 December 2009MaintBotAutomatic update of empty xrefs
21005view11:30, 14 November 2008MaintBot[[Pathway:Danio rerio:Biogenic Amine Synthesis]] moved to [[Pathway:WP154]]: Moved to stable identifier
12040view08:45, 15 May 2008MaintBotAdded to category $category
12038view08:45, 15 May 2008AlexanderPicoUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5-hydroxy-tryptophanMetabolite
ASMTGeneProduct
AcetylcholineMetabolite
AcetylserotoninMetabolite
CHATGeneProduct100170938 (Entrez Gene)
COMTGeneProduct
CholineMetabolite
DBHGeneProduct30505 (Entrez Gene)
DopamineMetabolite
EpinephrineMetabolite
GABAMetabolite
GlutamateMetabolite
HDCGeneProduct793609 (Entrez Gene)
HistamineMetabolite
HistidineMetabolite
L-DOPAMetabolite
MAOAGeneProduct
MelatoninMetabolite
NorepinephrineMetabolite
PNMTGeneProduct
PhenylalanineMetabolite
SerotoninMetabolite
THGeneProduct30384 (Entrez Gene)
TryptophanMetabolite
TyrosineMetabolite
aanat1GeneProduct393677 (Entrez Gene)
acheGeneProduct114549 (Entrez Gene)
ddcGeneProduct406651 (Entrez Gene)
gad1GeneProduct378441 (Entrez Gene)
pahGeneProduct378962 (Entrez Gene)
tph1GeneProduct352943 (Entrez Gene)
zgc:112198GeneProduct550403 (Entrez Gene)

Annotated Interactions

No annotated interactions

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