Nuclear receptors meta-pathway (Homo sapiens)

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3, 16CAR target genesCAR/PXR Ligand28KEAP1AntioxidantproteinsGSTA2GCLMNCOA6BIRC2MetabolismFTH1DNAJB1CYP3A4TNFAIP3JUNDrug and steroidmetabolismSNAI2CCL20CES2CDKN1CNRG1UGT1A1HSP90AB1SRXN1PDGFBFGF19Cell proliferationand apoptosisCES5ADNERSCNN1ATranscriptionfactorsEHHADHMYOFTSC22D3FGFBP1UGT1A3DNAJC15UGT1A4SLC2A14GSRIL17BBile acid &xenobiotics transportCXCR7AGERABCC2CYP1B1NQO1NCOA2GSTA2GPAMIP6K3ANGPTL4ABHD2CBR3ABCB1SERTAD2SERPINA1OtherGSTP1UGT1A4Phase 2metabolismCYP2B6GSTA4UGT1A9EGR1SLC2A12PCK1MT1IPPPP1R14CABCC5ABCC3AMIGO2GPR153NFE2L2CCL2G6PDUGT1A6SLC19A2B3GNT5NR1H4DNAJC7CES3CYP4A11CYP3A4ABCC3SLC10A1TXNRD3JUNBUGT1A9PDK4HSPA1AMAFGUGT1A7SLC2A13AKAP13MGST3KTN1SLC2A8GSTA5EP300PGDPRDX1PTGS2PPP2R4SP1SLC2A5CYP8B1UGT1A1ABCC2CYP2A6BHLHE40InflammationCYP2A6CYP2C9IL1BGSTA1ARL5BMFGE8CYP1A2GCLCCo-activatorsNR0B2CYP7A1ABCG5TGFB2TXNRD1SOD3CYP7A1JUNACAA1CYP2C19CUL1STOMSMC1ANAV3GCC1MGST1CYP3A4SLC2A7SMARCA1SRCSLC7A5ANKRD1SEC14L1UGT1A7KAT2BSLC2A4S100PNR0B2BAATNR3C1PPARDIL12ATranscriptionfactorsCYP2B6SLC2A10TXNGPX2ADH7SLC27A5DegradationBIRC3bile acidconjugationRXRASLC2A3TGFB1EPB41L4BIL11HBEGFUGT1A3TGFAPPARASLC7A11UGT1A9SLC2A2GSTT2TGFBR3SULT2A1ABCB11ZIC2IRS2IFNGSPRY1ALDH3A1GSTT1Bile acidneosynthesisENC1SULT1A1CYP2A6POU5F1TNS4RGS2CYP1A1PRRG4NR0B2CYP7A1GPR115MGST2FGD4ABCB4SLC2A6TGFBR2UGT2B4Cell proliferationand differentiationCYP4A11SQSTM1THBDMGAMNR1H3PRDX6SPINK13CES4AHSP90AA1UGT1A6CAP2CPEB4SLC2A11SULT2A1ABCG8SULT2A1SDPRGSTA3PPARGC1AESR1SRGNGGT1EDN2IL12BUGT2B7CDC42EP3HGFETNK2HMOX1SP1POLKPMP2ME1PPARGC1ANR1I3NFKB2SLC2A1MAFFSERPINB9PLK2GPX3HSP90AA1ALAS1CYP3A5ALOX5APCYP3A7UGT1A3EPHA3LRRC8ASLC2A9GADD45BSTAT3NCOA1SREBF1SLC26A2FKBP5SLCO2B1FTLCBR1UGT1A4EPHA2PDE4BBLVRBCES1SERPINB2CES3PTGR1FGF13TGFB1PPARAACOX1ABCC4FASN2551255152612135462553849254133495134849553325253325415510315511151491149NR1I3498192322, 47885148152554821495463344445641123113339554913LigandDNAJC7HSP90AA1CoregulatorsGenesTATA boxPBREMRXRANR1I3LigandCo-activatorsNCOA1EGFR pathwayEP300UGT1A6AHRR5, 25, 2733SRCCDKN1BAIP33CYP1B18, 11, 25, 27, 33UGT1A1ALDH3A15, 25, 278GSTA225, 27AHRJUND50NQO125, 27IGFBP137NFE2L227BAX33JUN34CYP1A28, 11, 25, 27, 33EGFRHSP90AA1TNFPTGES3IL230HES120ARNTCDC37CYP1A18, 11, 25, 27, 33AHRARNTAIPSRCSRCCDC37AHRARNTAHRLigandLigandLigandXREGenesTATA boxUGT1A95, 23HepatocyteproliferationNR1H323SCP223CPT1A23APOC323FABP123CCND1PLTP23DBI23APOA223CPT22323APOA1CYP4A1123ACADM2323CDK4CYP7A123MYC23mitochondrialomega-oxidation23SLC27A1Cholesterolcatabolism23peroxisomalbeta-oxidationKLK1523APOA523CDK1CYP8B123PPAR alpha ligand23PPARAGenesTATA boxPPREPPARARXRALigandlipoproteinmetabolismfatty acidtransportmitochondrialbeta-oxidationPXR target genes13, 24SLCO1B124HSP90AA1NR1I2SRPX2NCOA3FOXO1CYP4F1236CYP3A424UGT1A125DNAJC724ABCC424NRIP1UnknownCYP2B6GSTA22524PSMC5PPARGC1ANCOA1NCOA2ABCB124NR1I2LigandCoregulatorsGenesTATA boxXRERXRANR1I2LigandAhR LigandCo-activatorsGenesTATA boxNR1I3NR1I2NR3C1RXRA22, 47NR1I3NR1I2NR3C1HSP90AA1GR ligandp23HSP90AA1p23NR3C110, 43HSP90AA1p23NR3C110LigandNR3C1Ligand10LigandLigandNR3C1NR3C1LigandLigandGREGenesTATA boxNR3C1NR3C1LigandLigandnGRECoregulatorsGR inhibitorytarget genesLXR ligandNR1H3LigandRXRA22, 47PTGES3RXRANR1H322, 47CYP2B6CYP2C94949GenesTATA boxVDREVDR target genesVDR10, 35LigandRXRACYP3A449VDRVDR ligandRXRAVDRLigandER ligandESR1ESR1LigandLigandGenesTATA boxEREESR1LigandESR1LigandESR16ESR1ESR1LigandLigandCoregulatorsER target genes42GenesTATA boxNR1H3LigandLXRERXRALXR target genes22, 47FXR ligandNR1H4RXRA26LigandGenesTATA boxNR1H4RXRA26LigandFXREBile aciddetoxification41NR1H426LigandUGT1A4UGT1A655UGT1A9UGT1A355CYP2C9CYP3A52525CYP2C19SULT2A125ABCC2449ABCC3EHHADH4951FOXO1Inflammation36Growth andapoptosis1Signaltransduction11Other1Inflammation1Growth andapoptosisSignaltransduction1Metabolism11Transport1Other1NuclearreceptorsFXR Target genesOtherGR stimulatorytarget genesMulti-drugresistanceDrug and steroidmetabolismPhase 2metabolismMulti-drugresistanceOtherOtherPhase 2metabolismDrug and steroidmetabolismPhase 2metabolismOtherDrug and steroidmetabolismMulti-drugresistanceTranscriptionfactorsOtherDrug and steroidmetabolismTranscriptionfactorsOtherDrug and steroidmetabolismPPAR alphatarget genesAhR target genesGenesTATA boxRXRALigandARENRF2 targetgenesOtherPhase 1proteins4646Phase 2proteinsGSTM546GSTM1GSTM2GSTM3GSTM4TransportSLC5A246SLC5A1SLC5A4SLC5A10SLC5A9SLC5A6SLC5A11SLC5A12SLC5A3SLC5A7SLC5A8SLC5A5SLC6A2SLC6A1SLC6A4SLC6A11SLC6A9SLC6A6SLC6A13SLC6A14SLC6A3SLC6A7SLC6A8SLC6A5SLC6A16SLC6A15SLC6A18SLC6A20SLC6A17SLC6A19SLC39A2SLC39A1SLC39A4SLC39A10SLC39A9SLC39A6SLC39A11SLC39A12SLC39A3SLC39A7SLC39A8SLC39A5SLC39A13SLC39A14Growth factorsand receptorsNFE2L246NRF2 ligandKEAP1NFE2L2LigandNFE2L2NFE2L2SCD


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Bibliography

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History

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CompareRevisionActionTimeUserComment
126680view16:51, 11 June 2023EgonwFixed character encoding issues
126012view11:37, 26 March 2023EgonwWrong ligand term
125859view10:46, 13 March 2023DeSlFixed last 'ligand' classified as protein
125858view10:44, 13 March 2023DeSlResolved typo in description
125857view10:43, 13 March 2023DeSlRemoved empty comment from Description
125856view10:42, 13 March 2023DeSlConnected unconnected line
125855view10:41, 13 March 2023DeSlConverted textLabels 'ligand; to DataNode Metabolite, with ChEBI annotation; changed two protein datanodes to metaboliute for ligand.
125833view07:00, 13 March 2023EgonwAdded ChEBI identifiers for ligands
120815view15:30, 11 January 2022SusanOntology Term : 'transcription factor mediated signaling pathway' added !
117808view14:40, 22 May 2021EweitzModified title
115341view14:20, 14 February 2021EgonwMade more pathways clickable
103038view11:54, 2 February 2019MaintBotReplaced an outdated Ensembl identifiers with the new one.
97489view13:23, 23 May 2018Fehrhartlayout
97488view13:17, 23 May 2018Fehrhartadded annotations
97487view13:08, 23 May 2018Fehrhartadded annotations
97484view12:58, 23 May 2018FehrhartModified description
97483view12:56, 23 May 2018Fehrhartadded annotations
97481view12:50, 23 May 2018Fehrhartadded annotations
97480view12:42, 23 May 2018Fehrhartadded annotations
97479view12:35, 23 May 2018Fehrhartadded annotations
97478view12:12, 23 May 2018FehrhartModified description
97477view12:11, 23 May 2018FehrhartModified description
97476view12:07, 23 May 2018Fehrhartall connections done (hopefully)
97475view12:04, 23 May 2018Fehrhartconnections
97474view12:02, 23 May 2018Fehrhartconnections...
97473view12:00, 23 May 2018Fehrhartfixed connections
97472view11:58, 23 May 2018Fehrhartfixed connections
97471view11:56, 23 May 2018Fehrhartfixed connections
97470view11:55, 23 May 2018Fehrhartfixed more connections
97469view11:53, 23 May 2018Fehrhartfixed more connections
97467view09:20, 23 May 2018Fehrhartfixed more connections
97463view08:48, 22 May 2018Fehrhartfixed connections
87959view13:12, 25 July 2016ElisaOntology Term : 'regulatory pathway' added !
83040view04:29, 18 November 2015Mkutmonfixed issue with references
83016view13:30, 17 November 2015FehrhartUpdate of outdated identifiers
79825view08:28, 17 April 2015EgonwFixed the Ensembl data source.
78569view14:50, 7 January 2015MaintBotadded missing graphIds
78210view14:44, 14 December 2014EgonwChanged schema.
78209view14:42, 14 December 2014MaintBotModified title
78095view11:38, 2 December 2014RiannefijtenNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABCB11GeneProductENSG00000073734 (Ensembl)
ABCB1GeneProductENSG00000085563 (Ensembl)
ABCB4GeneProductENSG00000005471 (Ensembl)
ABCC2GeneProductENSG00000023839 (Ensembl)
ABCC3GeneProductENSG00000108846 (Ensembl)
ABCC4GeneProductENSG00000125257 (Ensembl)
ABCC5GeneProductENSG00000114770 (Ensembl)
ABCG5GeneProductENSG00000138075 (Ensembl)
ABCG8GeneProductENSG00000143921 (Ensembl)
ABHD2GeneProductENSG00000140526 (Ensembl)
ACAA1GeneProductENSG00000060971 (Ensembl)
ACADMGeneProductENSG00000117054 (Ensembl)
ACOX1GeneProductENSG00000161533 (Ensembl)
ADH7GeneProductENSG00000196344 (Ensembl)
AGERGeneProductENSG00000204305 (Ensembl)
AHRGeneProductENSG00000106546 (Ensembl)
AHRRGeneProductENSG00000063438 (Ensembl)
AIPGeneProductENSG00000110711 (Ensembl)
AKAP13GeneProductENSG00000170776 (Ensembl)
ALAS1GeneProductENSG00000023330 (Ensembl)
ALDH3A1GeneProductENSG00000108602 (Ensembl)
ALOX5APGeneProductENSG00000132965 (Ensembl)
AMIGO2GeneProductENSG00000139211 (Ensembl)
ANGPTL4GeneProductENSG00000167772 (Ensembl)
ANKRD1GeneProductENSG00000148677 (Ensembl)
APOA1GeneProductENSG00000118137 (Ensembl)
APOA2GeneProductENSG00000158874 (Ensembl)
APOA5GeneProductENSG00000110243 (Ensembl)
APOC3GeneProductENSG00000110245 (Ensembl)
ARL5BGeneProductENSG00000165997 (Ensembl)
ARNTGeneProduct405 (Entrez Gene)
Antioxidant proteinsPathway
B3GNT5GeneProductENSG00000176597 (Ensembl)
BAATGeneProductENSG00000136881 (Ensembl)
BAX GeneProductENSG00000087088 (Ensembl)
BHLHE40GeneProductENSG00000134107 (Ensembl)
BIRC2GeneProductENSG00000110330 (Ensembl)
BIRC3GeneProductENSG00000023445 (Ensembl)
BLVRBGeneProductENSG00000090013 (Ensembl)
Bile acid detoxificationPathway
Bile acid neosynthesisPathway
Bile acid & xenobiotics transportPathway
CAP2GeneProductENSG00000112186 (Ensembl)
CBR1GeneProductENSG00000159228 (Ensembl)
CBR3GeneProductENSG00000159231 (Ensembl)
CCL20GeneProductENSG00000115009 (Ensembl)
CCL2GeneProductENSG00000108691 (Ensembl)
CCND1GeneProductENSG00000110092 (Ensembl)
CDC37GeneProductENSG00000105401 (Ensembl)
CDC42EP3GeneProductENSG00000163171 (Ensembl)
CDK1GeneProductENSG00000170312 (Ensembl)
CDK4GeneProductENSG00000135446 (Ensembl)
CDKN1BGeneProductENSG00000111276 (Ensembl)
CDKN1CGeneProductENSG00000129757 (Ensembl)
CES1GeneProductENSG00000198848 (Ensembl)
CES2GeneProductENSG00000172831 (Ensembl)
CES3GeneProductENSG00000172828 (Ensembl)
CES4AGeneProductENSG00000172824 (Ensembl)
CES5AGeneProductENSG00000159398 (Ensembl)
CPEB4GeneProductENSG00000113742 (Ensembl)
CPT1AGeneProductENSG00000110090 (Ensembl)
CPT2GeneProductENSG00000157184 (Ensembl)
CUL1GeneProductENSG00000055130 (Ensembl)
CXCR7GeneProductENSG00000144476 (Ensembl)
CYP1A1GeneProductENSG00000140465 (Ensembl)
CYP1A2GeneProductENSG00000140505 (Ensembl)
CYP1B1GeneProductENSG00000138061 (Ensembl)
CYP2A6GeneProductENSG00000255974 (Ensembl)
CYP2B6GeneProductENSG00000197408 (Ensembl)
CYP2C19GeneProductENSG00000165841 (Ensembl)
CYP2C9GeneProductENSG00000138109 (Ensembl)
CYP3A4GeneProductENSG00000160868 (Ensembl)
CYP3A5GeneProductENSG00000106258 (Ensembl)
CYP3A7GeneProductENSG00000160870 (Ensembl)
CYP4A11GeneProductENSG00000187048 (Ensembl)
CYP4F12GeneProductENSG00000186204 (Ensembl)
CYP7A1GeneProductENSG00000167910 (Ensembl)
CYP8B1GeneProductENSG00000180432 (Ensembl)
Cell proliferation and apoptosisPathway
Cell proliferation

and differentiation

Pathway
Cholesterol catabolismPathway
Co-activators
DBIGeneProductENSG00000155368 (Ensembl)
DNAJB1GeneProductENSG00000132002 (Ensembl)
DNAJC15GeneProductENSG00000120675 (Ensembl)
DNAJC7GeneProductENSG00000168259 (Ensembl)
DNERGeneProductENSG00000187957 (Ensembl)
DegradationPathway
Drug and steroid metabolismPathway
EDN2GeneProductENSG00000127129 (Ensembl)
EGFR pathwayPathway
EGFRGeneProductENSG00000146648 (Ensembl)
EGR1GeneProductENSG00000120738 (Ensembl)
EHHADHGeneProductENSG00000113790 (Ensembl)
ENC1GeneProductENSG00000171617 (Ensembl)
EP300GeneProductENSG00000100393 (Ensembl)
EPB41L4BGeneProductENSG00000095203 (Ensembl)
EPHA2GeneProductENSG00000142627 (Ensembl)
EPHA3GeneProductENSG00000044524 (Ensembl)
ESR1GeneProductENSG00000091831 (Ensembl)
ETNK2GeneProductENSG00000143845 (Ensembl)
FABP1GeneProductENSG00000163586 (Ensembl)
FASNGeneProductENSG00000169710 (Ensembl)
FGD4GeneProductENSG00000139132 (Ensembl)
FGF13GeneProductENSG00000129682 (Ensembl)
FGF19GeneProductENSG00000162344 (Ensembl)
FGFBP1GeneProductENSG00000137440 (Ensembl)
FKBP5GeneProductENSG00000096060 (Ensembl)
FOXO1GeneProductENSG00000150907 (Ensembl)
FTH1GeneProductENSG00000167996 (Ensembl)
FTLGeneProductENSG00000087086 (Ensembl)
G6PDGeneProductENSG00000160211 (Ensembl)
GADD45BGeneProductENSG00000099860 (Ensembl)
GCC1GeneProductENSG00000179562 (Ensembl)
GCLCGeneProductENSG00000001084 (Ensembl)
GCLMGeneProductENSG00000023909 (Ensembl)
GGT1GeneProductENSG00000100031 (Ensembl)
GPAMGeneProductENSG00000119927 (Ensembl)
GPR115GeneProductENSG00000153294 (Ensembl)
GPR153GeneProductENSG00000158292 (Ensembl)
GPX2GeneProductENSG00000176153 (Ensembl)
GPX3GeneProductENSG00000211445 (Ensembl)
GSRGeneProductENSG00000104687 (Ensembl)
GSTA1GeneProductENSG00000243955 (Ensembl)
GSTA2GeneProductENSG00000244067 (Ensembl)
GSTA3GeneProductENSG00000174156 (Ensembl)
GSTA4GeneProductENSG00000170899 (Ensembl)
GSTA5GeneProductENSG00000182793 (Ensembl)
GSTM1GeneProductENSG00000134184 (Ensembl)
GSTM2GeneProductENSG00000213366 (Ensembl)
GSTM3GeneProductENSG00000134202 (Ensembl)
GSTM4GeneProductENSG00000168765 (Ensembl)
GSTM5GeneProductENSG00000134201 (Ensembl)
GSTP1GeneProductENSG00000084207 (Ensembl)
GSTT1GeneProductENSG00000277656 (Ensembl)
GSTT2GeneProductENSG00000099984 (Ensembl)
Growth and apoptosisPathway
Growth factors and receptorsPathway
HBEGFGeneProductENSG00000113070 (Ensembl)
HES1GeneProductENSG00000114315 (Ensembl)
HGFGeneProductENSG00000019991 (Ensembl)
HMOX1GeneProductENSG00000100292 (Ensembl)
HSP90AA1 GeneProductENSG00000080824 (Ensembl)
HSP90AA1GeneProductENSG00000080824 (Ensembl)
HSP90AB1GeneProductENSG00000096384 (Ensembl)
HSPA1AGeneProductENSG00000204389 (Ensembl)
Hepatocyte proliferationPathwayin mice (possibly also in humans?)
IFNGGeneProductENSG00000111537 (Ensembl)
IGFBP1 GeneProductENSG00000146678 (Ensembl)
IL11GeneProductENSG00000095752 (Ensembl)
IL12AGeneProductENSG00000168811 (Ensembl)
IL12BGeneProductENSG00000113302 (Ensembl)
IL17BGeneProductENSG00000127743 (Ensembl)
IL1BGeneProductENSG00000125538 (Ensembl)
IL2 GeneProductENSG00000109471 (Ensembl)
IP6K3GeneProductENSG00000161896 (Ensembl)
IRS2GeneProductENSG00000185950 (Ensembl)
InflammationPathway
JUNBGeneProductENSG00000171223 (Ensembl)
JUNDGeneProductENSG00000130522 (Ensembl)
JUNGeneProductENSG00000177606 (Ensembl)
KAT2BGeneProductENSG00000114166 (Ensembl)
KEAP1GeneProductENSG00000079999 (Ensembl)
KLK15GeneProductENSG00000174562 (Ensembl)
KTN1GeneProductENSG00000126777 (Ensembl)
LRRC8AGeneProductENSG00000136802 (Ensembl)
Ligand
Ligand ProteinOmeprazole, TCDD, PCB
MAFFGeneProductENSG00000185022 (Ensembl)
MAFGGeneProductENSG00000197063 (Ensembl)
ME1GeneProductENSG00000065833 (Ensembl)
MFGE8GeneProductENSG00000140545 (Ensembl)
MGAMGeneProductENSG00000179087 (Ensembl)
MGST1GeneProductENSG00000008394 (Ensembl)
MGST2GeneProductENSG00000085871 (Ensembl)
MGST3GeneProductENSG00000143198 (Ensembl)
MT1IPGeneProduct644314 (Entrez Gene)
MYCGeneProductENSG00000136997 (Ensembl)
MYOFGeneProductENSG00000138119 (Ensembl)
MetabolismPathway
Multi-drug resistancePathway
NAV3GeneProductENSG00000067798 (Ensembl)
NCOA1GeneProductENSG00000084676 (Ensembl)
NCOA2GeneProductENSG00000140396 (Ensembl)
NCOA3GeneProductENSG00000124151 (Ensembl)
NCOA6GeneProductENSG00000198646 (Ensembl)
NFE2L2GeneProductENSG00000116044 (Ensembl)
NFKB2GeneProductENSG00000077150 (Ensembl)
NQO1GeneProductENSG00000181019 (Ensembl)
NR0B2GeneProductENSG00000131910 (Ensembl)
NR1H3GeneProductENSG00000025434 (Ensembl)
NR1H4GeneProductENSG00000012504 (Ensembl)
NR1I2GeneProductENSG00000144852 (Ensembl)
NR1I3GeneProductENSG00000143257 (Ensembl)
NR3C1GeneProductENSG00000113580 (Ensembl)
NRG1GeneProductENSG00000157168 (Ensembl)
NRIP1GeneProductENSG00000180530 (Ensembl)
Nuclear receptorsPathway
OtherPathway
PCK1GeneProductENSG00000124253 (Ensembl)
PDE4BGeneProductENSG00000184588 (Ensembl)
PDGFBGeneProductENSG00000100311 (Ensembl)
PDK4GeneProductENSG00000004799 (Ensembl)
PGDGeneProductENSG00000142657 (Ensembl)
PLK2GeneProductENSG00000145632 (Ensembl)
PLTPGeneProductENSG00000100979 (Ensembl)
PMP2GeneProductENSG00000147588 (Ensembl)
POLKGeneProductENSG00000122008 (Ensembl)
POU5F1GeneProductENSG00000204531 (Ensembl)
PPAR alpha ligand
PPARAGeneProductENSG00000186951 (Ensembl)
PPARDGeneProductENSG00000112033 (Ensembl)
PPARGC1AGeneProductENSG00000109819 (Ensembl)
PPP1R14CGeneProductENSG00000198729 (Ensembl)
PPP2R4GeneProductENSG00000119383 (Ensembl) plays a role in translocation of CAR
PRDX1GeneProductENSG00000117450 (Ensembl)
PRDX6GeneProductENSG00000117592 (Ensembl)
PRRG4GeneProductENSG00000135378 (Ensembl)
PSMC5GeneProductENSG00000087191 (Ensembl)
PTGES3GeneProductENSG00000110958 (Ensembl)
PTGR1GeneProductENSG00000106853 (Ensembl)
PTGS2GeneProductENSG00000073756 (Ensembl)
Phase 1

proteins

Pathway
Phase 2 metabolismPathway
Phase 2

proteins

Pathway
RGS2GeneProductENSG00000116741 (Ensembl)
RXRAGeneProductENSG00000186350 (Ensembl)
S100PGeneProductENSG00000163993 (Ensembl)
SCDGeneProductENSG00000099194 (Ensembl)
SCNN1AGeneProductENSG00000111319 (Ensembl)
SCP2GeneProductENSG00000116171 (Ensembl)
SDPRGeneProductENSG00000168497 (Ensembl)
SEC14L1GeneProductENSG00000129657 (Ensembl)
SERPINA1GeneProductENSG00000197249 (Ensembl)
SERPINB2GeneProductENSG00000197632 (Ensembl)
SERPINB9GeneProductENSG00000170542 (Ensembl)
SERTAD2GeneProductENSG00000179833 (Ensembl)
SLC10A1GeneProductENSG00000100652 (Ensembl) inhibition
SLC19A2GeneProductENSG00000117479 (Ensembl)
SLC26A2GeneProductENSG00000155850 (Ensembl)
SLC27A1GeneProductENSG00000130304 (Ensembl)
SLC27A5GeneProductENSG00000083807 (Ensembl)
SLC2A10GeneProductENSG00000197496 (Ensembl)
SLC2A11GeneProductENSG00000133460 (Ensembl)
SLC2A12GeneProductENSG00000146411 (Ensembl)
SLC2A13GeneProductENSG00000151229 (Ensembl)
SLC2A14GeneProductENSG00000173262 (Ensembl)
SLC2A1GeneProductENSG00000117394 (Ensembl)
SLC2A2GeneProductENSG00000163581 (Ensembl)
SLC2A3GeneProductENSG00000059804 (Ensembl)
SLC2A4GeneProductENSG00000181856 (Ensembl)
SLC2A5GeneProductENSG00000142583 (Ensembl)
SLC2A6GeneProductENSG00000160326 (Ensembl)
SLC2A7GeneProductENSG00000197241 (Ensembl)
SLC2A8GeneProductENSG00000136856 (Ensembl)
SLC2A9GeneProductENSG00000109667 (Ensembl)
SLC39A10GeneProductENSG00000196950 (Ensembl)
SLC39A11GeneProductENSG00000133195 (Ensembl)
SLC39A12GeneProductENSG00000148482 (Ensembl)
SLC39A13GeneProductENSG00000165915 (Ensembl)
SLC39A14GeneProductENSG00000104635 (Ensembl)
SLC39A1GeneProductENSG00000143570 (Ensembl)
SLC39A2GeneProductENSG00000165794 (Ensembl)
SLC39A3GeneProductENSG00000141873 (Ensembl)
SLC39A4GeneProductENSG00000147804 (Ensembl)
SLC39A5GeneProductENSG00000139540 (Ensembl)
SLC39A6GeneProductENSG00000141424 (Ensembl)
SLC39A7GeneProductENSG00000112473 (Ensembl)
SLC39A8GeneProductENSG00000138821 (Ensembl)
SLC39A9GeneProductENSG00000029364 (Ensembl)
SLC5A10GeneProductENSG00000154025 (Ensembl)
SLC5A11GeneProductENSG00000158865 (Ensembl)
SLC5A12GeneProductENSG00000148942 (Ensembl)
SLC5A1GeneProductENSG00000100170 (Ensembl)
SLC5A2GeneProductENSG00000140675 (Ensembl)
SLC5A3GeneProductENSG00000198743 (Ensembl)
SLC5A4GeneProductENSG00000100191 (Ensembl)
SLC5A5GeneProductENSG00000105641 (Ensembl)
SLC5A6GeneProductENSG00000138074 (Ensembl)
SLC5A7GeneProductENSG00000115665 (Ensembl)
SLC5A8GeneProductENSG00000256870 (Ensembl)
SLC5A9GeneProductENSG00000117834 (Ensembl)
SLC6A11GeneProductENSG00000132164 (Ensembl)
SLC6A13GeneProductENSG00000010379 (Ensembl)
SLC6A14GeneProductENSG00000268104 (Ensembl)
SLC6A15GeneProductENSG00000072041 (Ensembl)
SLC6A16GeneProductENSG00000063127 (Ensembl)
SLC6A17GeneProductENSG00000197106 (Ensembl)
SLC6A18GeneProductENSG00000164363 (Ensembl)
SLC6A19GeneProductENSG00000174358 (Ensembl)
SLC6A1GeneProductENSG00000157103 (Ensembl)
SLC6A20GeneProductENSG00000163817 (Ensembl)
SLC6A2GeneProductENSG00000103546 (Ensembl)
SLC6A3GeneProductENSG00000142319 (Ensembl)
SLC6A4GeneProductENSG00000108576 (Ensembl)
SLC6A5GeneProductENSG00000165970 (Ensembl)
SLC6A6GeneProductENSG00000131389 (Ensembl)
SLC6A7GeneProductENSG00000011083 (Ensembl)
SLC6A8GeneProductENSG00000130821 (Ensembl)
SLC6A9GeneProductENSG00000196517 (Ensembl)
SLC7A11GeneProductENSG00000151012 (Ensembl)
SLC7A5GeneProductENSG00000103257 (Ensembl)
SLCO1B1GeneProductENSG00000134538 (Ensembl)
SLCO2B1GeneProductENSG00000137491 (Ensembl) inhibition
SMARCA1GeneProductENSG00000102038 (Ensembl)
SMC1AGeneProductENSG00000072501 (Ensembl)
SNAI2GeneProductENSG00000019549 (Ensembl)
SOD3GeneProductENSG00000109610 (Ensembl)
SP1GeneProductENSG00000185591 (Ensembl)
SPINK13GeneProductENSG00000214510 (Ensembl)
SPRY1GeneProductENSG00000164056 (Ensembl)
SQSTM1GeneProductENSG00000161011 (Ensembl)
SRC GeneProductENSG00000197122 (Ensembl)
SRC GeneProductENSG00000197122 (Ensembl)
SRCGeneProductENSG00000197122 (Ensembl)
SREBF1GeneProductENSG00000072310 (Ensembl)
SRGNGeneProductENSG00000122862 (Ensembl)
SRPX2GeneProductENSG00000102359 (Ensembl)
SRXN1GeneProductENSG00000172070 (Ensembl)
STAT3GeneProductENSG00000168610 (Ensembl)
STOMGeneProductENSG00000148175 (Ensembl)
SULT1A1GeneProductENSG00000196502 (Ensembl) during fasting
SULT2A1GeneProductENSG00000105398 (Ensembl)
Signal transductionPathway
TGFAGeneProductENSG00000163235 (Ensembl)
TGFB1GeneProductENSG00000105329 (Ensembl)
TGFB2GeneProductENSG00000092969 (Ensembl)
TGFBR2GeneProductENSG00000163513 (Ensembl)
TGFBR3GeneProductENSG00000069702 (Ensembl)
THBDGeneProductENSG00000178726 (Ensembl)
TNF GeneProductENSG00000232810 (Ensembl)
TNFAIP3GeneProductENSG00000118503 (Ensembl)
TNS4GeneProductENSG00000131746 (Ensembl)
TSC22D3GeneProductENSG00000157514 (Ensembl)
TXNGeneProductENSG00000136810 (Ensembl)
TXNRD1GeneProductENSG00000198431 (Ensembl)
TXNRD3GeneProductENSG00000197763 (Ensembl)
Transcription factorsPathway
TransportPathway
UGT1A1GeneProductENSG00000241635 (Ensembl)
UGT1A3GeneProductENSG00000243135 (Ensembl)
UGT1A4GeneProductENSG00000244474 (Ensembl)
UGT1A6GeneProductENSG00000167165 (Ensembl)
UGT1A7GeneProductENSG00000244122 (Ensembl)
UGT1A9GeneProductENSG00000241119 (Ensembl)
UGT2B4GeneProductENSG00000156096 (Ensembl)
UGT2B7GeneProductENSG00000171234 (Ensembl)
Unknown
VDRGeneProductENSG00000111424 (Ensembl)
ZIC2GeneProductENSG00000043355 (Ensembl)
bile acid conjugationPathway
fatty acid transportPathway
lipoprotein metabolismPathway
mitochondrial beta-oxidationPathway
mitochondrial omega-oxidationPathway
p23GeneProductENSG00000110958 (Ensembl)
peroxisomal beta-oxidationPathway

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2882"
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