miRNA degrading enzymes (Homo sapiens)

Revision as of 08:47, 25 June 2018 by Madeomuga (Talk | contribs)

Description

No description

: "MicroRNAs (miRNAs) are short (∼22 nucleotide) RNAs that are important for the regulation of numerous biological processes. Accordingly, the expression of miRNAs is itself tightly controlled by mechanisms acting at the level of transcription as well as processing of miRNA precursors. Recently, active degradation of mature miRNAs has been identified as another mechanism that is important for miRNA homeostasis. Here we review the molecular factors and cellular conditions that promote miRNA turnover. We also discuss what is known about the physiological relevance of miRNA decay." Großhans H. et al 2012

View approved pathways at the new wikipathways.org.

Rüegger S, Großhans H; ''MicroRNA turnover: when, how, and why.''; Trends Biochem Sci, 2012 PubMed Europe PMC Scholia
Zhang Z, Qin YW, Brewer G, Jing Q; ''MicroRNA degradation and turnover: regulating the regulators.''; Wiley Interdiscip Rev RNA, 2012 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
120818	view	19:10, 11 January 2022	Khanspers	Modified description
120603	view	22:28, 17 December 2021	Khanspers	Ontology Term : 'microRNA pathway' added !
120602	view	22:27, 17 December 2021	Khanspers	updated interactions
120601	view	22:22, 17 December 2021	Khanspers	MOved comment to Description
97927	view	08:57, 25 June 2018	Madeomuga	Modified description
97923	view	08:47, 25 June 2018	Madeomuga	New pathway

Name	Type	Database reference
PNPT1	GeneProduct	ENSG00000138035 (Ensembl)
RRP41	GeneProduct	Q9NPD3 (Uniprot-TrEMBL)
XRN1	GeneProduct	ENSG00000114127 (Ensembl)

No annotated interactions