Osteoblast signaling (Rattus norvegicus)
From WikiPathways
Description
Osteoblasts are specialized, terminally differentiated uninucleated cells responsible for bone formation. Their activity is tightly regulated by external stimuli, originating from e.g. the parathyroid glands, osteocytes, etc. Along with osteoclasts, which are responsible for bone degradation, osteoblasts are key regulators of the shape and volume of bone tissue.
Quality Tags
Ontology Terms
Bibliography
- Shymanskyi I, Lisakovska O, Mazanova A, Labudzynskyi D, Veliky M; ''Vitamin D(3) Modulates Impaired Crosstalk Between RANK and Glucocorticoid Receptor Signaling in Bone Marrow Cells After Chronic Prednisolone Administration.''; Front Endocrinol (Lausanne), 2018 PubMed Europe PMC Scholia
History
View all... |
External references
DataNodes
View all... |
Name | Type | Database reference | Comment |
---|---|---|---|
Bone sialoprotein | GeneProduct | 25295 (Entrez Gene) | |
Collagen 1 | GeneProduct | 29393 (Entrez Gene) | |
FGF-23 | GeneProduct | 170583 (Entrez Gene) | |
NPT3 | GeneProduct | 25548 (Entrez Gene) | |
Osteocalcin | GeneProduct | 25295 (Entrez Gene) | |
Osteoprotegerin | GeneProduct | 25341 (Entrez Gene) | |
PDGF Ra | GeneProduct | 25267 (Entrez Gene) | |
PDGF Rb | GeneProduct | 24629 (Entrez Gene) | |
PDGF-BB | Metabolite | ||
PTH receptor | GeneProduct | 56813 (Entrez Gene) | |
Parathyroid hormone | GeneProduct | 24694 (Entrez Gene) | |
Phosphate | Metabolite | 18367 (ChEBI) | |
RANK ligand | GeneProduct | 117516 (Entrez Gene) | |
Sodium | Metabolite | 29101 (ChEBI) | |
Soluble RANK ligand | GeneProduct | ||
Vitamin D | Metabolite | 27300 (ChEBI) | |
avb3 integrin | GeneProduct |
Annotated Interactions
No annotated interactions