Hepatocyte growth factor receptor signaling (Anopheles gambiae)

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1RHOpathwayCDC42pathwayTrancriptionCytoplasmAKT PathwayTranscriptionRight Click for CommentsExtracellularRAC1pathwayAnoikisActinChanges in Cytoskeletonand Cell mobilityTranscriptionof Cox2AP-1AgaP_AGAP009628ITGA1CRKLMetSTAT3ELK1AgaP_AGAP009499AgaP_AGAP002986MAPK8AgaP_AGAP001103PIK3CAAgaP_AGAP002729MAPK3AgaP_AGAP009207RAP1BAgaP_AGAP011118AgaP_AGAP008532AgaP_AGAP001874RAF1HRASHGFAgaP_AGAP004320MAP4K1AgaP_AGAP008532AgaP_AGAP011768PTK2BAgaP_AGAP006510MAP2K2AgaP_AGAP009180PTK2BFOSAgaP_AGAP011118GAB1AgaP_AGAP002438INTBAgaP_AGAP000932AgaP_AGAP006510AgaP_AGAP006386PPP


Description

Signaling pathway of the Hepatocyte Growth Factor Receptor (Homo sapiens) also know as C-Met. The C-Met activation results in the stimulation of a variety of intracellular signalling pathways, which regulate several processes such as: motility, migration, proliferation and invasion.

Comments

GenMAPP remarks 
Converted to human by GenMAPP.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP313(r21339) with a 52% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Organ SL, Tsao MS; ''An overview of the c-MET signaling pathway.''; Ther Adv Med Oncol, 2011 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118650view15:03, 31 May 2021DeSlOntology Term : 'Rho/Rac/Cdc42 mediated signaling pathway' added !
118649view15:02, 31 May 2021DeSlOntology Term : 'hepatocyte' added !
118648view15:02, 31 May 2021DeSlAdded states to DataNodes iso textlabel "P'
118647view15:01, 31 May 2021DeSlConnected unconnected lines by converting to graphical lines
118646view15:00, 31 May 2021DeSlUpdated ReceptorSquare to binding in correct direction with lit. ref
118644view14:52, 31 May 2021DeSlAdded description from WP313
118038view11:50, 23 May 2021EweitzModified title
87668view08:55, 25 July 2016LindarieswijkOntology Term : 'scatter factor/hepatocyte growth factor signaling pathway' added !
79426view23:43, 21 March 2015Khanspersupdate schema
79425view23:42, 21 March 2015KhanspersReverted to version '18:46, 1 March 2011' by Khanspers
67876view16:58, 27 June 2013MaintBotUpdated to 2013 gpml schema
40460view18:46, 1 March 2011MaintBotRemoved redundant pathway information and comments
32288view13:10, 15 August 2009MaintBotFixed text labels
31841view12:29, 14 August 2009MaintBotFixed group labels
31316view20:16, 13 August 2009MaintBotFixed text labels
30804view23:47, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AgaP_AGAP000932GeneProduct1270418 (Entrez Gene)
AgaP_AGAP001103GeneProduct1282062 (Entrez Gene)
AgaP_AGAP001874GeneProduct1281247 (Entrez Gene)
AgaP_AGAP002438GeneProduct1273523 (Entrez Gene)
AgaP_AGAP002729GeneProduct1273239 (Entrez Gene)
AgaP_AGAP002986GeneProduct1272970 (Entrez Gene)
AgaP_AGAP004320GeneProduct1274463 (Entrez Gene) Interim Symbol: Dock1 predicted and Name: dedicator of cyto-kinesis 1 (predicted)
AgaP_AGAP006386GeneProduct1276998 (Entrez Gene)
AgaP_AGAP006510GeneProduct1277104 (Entrez Gene)
AgaP_AGAP008532GeneProduct1277441 (Entrez Gene)
AgaP_AGAP009180GeneProduct1280136 (Entrez Gene) Son of sevenless homolog 1 (Drosophila) (predicted)
AgaP_AGAP009207GeneProduct1280167 (Entrez Gene)
AgaP_AGAP009499GeneProduct1271411 (Entrez Gene)
AgaP_AGAP009628GeneProduct3292014 (Entrez Gene)
AgaP_AGAP011118GeneProduct1270807 (Entrez Gene)
AgaP_AGAP011768GeneProduct1280872 (Entrez Gene)
CRKLGeneProduct
ELK1GeneProduct
FOSGeneProduct
GAB1GeneProduct
HGFGeneProduct
HRASGeneProduct
INTBGeneProduct1272405 (Entrez Gene)
ITGA1GeneProduct
MAP2K2GeneProduct
MAP4K1GeneProduct
MAPK3GeneProduct
MAPK8GeneProduct
MetGeneProduct
PIK3CAGeneProduct
PTK2BGeneProduct
RAF1GeneProduct
RAP1BGeneProduct
STAT3GeneProduct

Annotated Interactions

No annotated interactions
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