Lac-Phe pathway (Mus musculus)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none L-phenylalanineABCC5(S)-lactateLac-PheCNDP2Lac-PheName: Lac-Phe pathwayOrganism: Mus musculus


Description

Lac-Phe is formed by Cndp2 and exported outside the cell, into the blood circulation by Abcc5. It is linked to food intake and obesity, where it is increased after exercise and suppresses food intake. Homology converted from WP5239

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Quality Tags

Image:Curated.pngApproved version

Ontology Terms

Pathway Ontology : disease pathway
Cell Type : epithelial cell
 

Bibliography

  1. ''''; , PubMed Europe PMC Scholia
  2. ''''; , PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
124561
Approved
view00:49, 9 November 2022EweitzModified description
123035view07:11, 20 June 2022EgonwRemoved the RHEA prefix
123030view08:39, 18 June 2022EgonwOntology Term : 'obesity' added !
123029view08:39, 18 June 2022EgonwOntology Term : 'signaling pathway' added !
123028view08:39, 18 June 2022EgonwOntology Term : 'classic metabolic pathway' added !
123025view08:38, 18 June 2022EgonwModified description
123022view08:36, 18 June 2022EgonwModified description
123020view08:30, 18 June 2022EgonwNew pathway

External references

DataNodes

Name  ↓Type  ↓Database reference  ↓Comment  ↓
(S)-lactateMetabolite16651 (ChEBI)
ABCC5GeneProductQ9R1X5 (Uniprot-TrEMBL)
CNDP2ProteinQ9D1A2 (Uniprot-TrEMBL)
L-phenylalanineMetabolite58095 (ChEBI)
Lac-PheMetabolite167456 (ChEBI)

Annotated Interactions

Source  ↓Target  ↓Type  ↓Database reference  ↓Comment  ↓
(S)-lactateLac-Phemim-conversion66724 (Rhea)
Lac-PheLac-Phe66720 (Rhea)
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP5240"
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