Fatty acid biosynthesis (Drosophila melanogaster)
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Description
The production of fatty acids from acetyl-CoA and NADPH through the use of enzymes known as fatty acid synthases is referred to as fatty acid synthesis. This biological process occurs within the cytoplasm of cells. The majority of acetyl-CoA that is transformed into fatty acids originates from carbohydrates through the glycolytic pathway.
Quality Tags
Ontology Terms
Bibliography
- de Renobales M, Blomquist GJ; ''Biosynthesis of medium chain fatty acids in Drosophila melanogaster.''; Arch Biochem Biophys, 1984 PubMed Europe PMC Scholia
- Keith AD; ''Fatty acid metabolism in Drosophila melanogaster: interaction between dietary fatty acids and de novo synthesis.''; Comp Biochem Physiol, 1967 PubMed Europe PMC Scholia
- Parvy JP, Napal L, Rubin T, Poidevin M, Perrin L, Wicker-Thomas C, Montagne J; ''Drosophila melanogaster Acetyl-CoA-carboxylase sustains a fatty acid-dependent remote signal to waterproof the respiratory system.''; PLoS Genet, 2012 PubMed Europe PMC Scholia
- Lowe PN, Rhodes S; ''Purification and characterization of [acyl-carrier-protein] acetyltransferase from Escherichia coli.''; Biochem J, 1988 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
3-L-Hydroxyacyl-CoA | Metabolite | ||
3-ketoacyl-CoA | Metabolite | CHEBI:57347 (ChEBI) | |
ACACB | GeneProduct | ||
ACSL4 | GeneProduct | ||
ACSL5 | GeneProduct | ||
ACSL6 | GeneProduct | ||
ATPCL | GeneProduct | 36760 (Entrez Gene) | |
AcCoAS | GeneProduct | 40348 (Entrez Gene) | |
Acetoacetyl-ACP | Metabolite | CHEBI:2393 (ChEBI) | |
Acetyl-ACP | Metabolite | C03939 (KEGG Compound) | |
Acetyl-CoA | Metabolite | 392413 (Chemspider) | |
Acetyl-synthase | |||
Acyl-CoA (n+2) | Metabolite | CHEBI:37554 (ChEBI) | |
Butyryl-ACP | Metabolite | CHEBI:3247 (ChEBI) | |
CG11198 | GeneProduct | 35761 (Entrez Gene) | |
CG1516 | GeneProduct | 36020 (Entrez Gene) | |
CG16935 | GeneProduct | 36540 (Entrez Gene) | |
CG3523 | GeneProduct | 33524 (Entrez Gene) | |
CG3961 | GeneProduct | 40056 (Entrez Gene) | |
CG6543 | GeneProduct | 36536 (Entrez Gene) | |
CG6984 | GeneProduct | 36926 (Entrez Gene) | |
CG9577 | GeneProduct | 33016 (Entrez Gene) | |
Citrate | Metabolite | 29081 (Chemspider) | |
Crotonoyl-ACP | Metabolite | ||
DECR1 | GeneProduct | ||
ECHDC1 | GeneProduct | ||
ECHDC2 | GeneProduct | ||
Fatty acyl CoA | Metabolite | CHEBI:37554 (ChEBI) | |
HADHSC | GeneProduct | ||
Long-Chain fatty acid | Metabolite | CHEBI:15904 (ChEBI) | |
Malonyl-ACP | Metabolite | C01209 (KEGG Compound) | |
Malonyl-CoA | Metabolite | HMDB0001175 (HMDB) | |
Oxaloacetate | Metabolite | 2509917 (Chemspider) | |
PECR | GeneProduct | ||
Palmitate | Metabolite | 440215 (Chemspider) | |
Palmitoyl-ACP | |||
Pyruvate | Metabolite | 96901 (Chemspider) | |
SCD | GeneProduct | 252579 (Entrez Gene) | |
Triacylglyceride Synthesis MAPP | Pathway | WP279 (WikiPathways) | |
beta-hydroxybutyryl | Metabolite | 644065 (PubChem-compound) | |
l(2)44DEa | GeneProduct | 46068 (Entrez Gene) | |
trans-delta2-enoyl-CoA | Metabolite | ||
yip2 | GeneProduct | 34313 (Entrez Gene) |
Annotated Interactions
No annotated interactions