Triacylglyceride synthesis (Caenorhabditis elegans)
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Dihydroxyacetone phosphate
Phosphatic acid
Glycerol-3-phosphate
Diacylglycerol
Fatty acyl CoA
Monoacylglycerol
Glycerol
Fatty Acid Synthesis
Degradation
Path
Triacylglycerol
Fatty Acid Synthesis
Fatty Acyl CoA
Dihydroxyacetonephosphate
Lysophosphatic Acid
acyldihydroxyacetonephosphate
C05D11.7
acl-7
F53C3.13
AYR1
acl-11
MGAT3
LPL
lipase
C46C11.1
Y53G8B.2
gly-20
AGPAT3
AGPAT4
K11H3.1
PPAP2C
PPAP2B
DGAT1
R11F4.1
acl-2
gly-14
AGPAT2
ads-1
LIPC
acl-6
GK2
Description
Most fats within this species are stored as triglycerides (TGs). TGs are composed out of a glycerol backbone, connecting three fatty acid chains.
Comments
GenMAPP notes
Created by Magali Jaillard, Marijke Vermeer, Michiel Adrieans, Ron Schormans and Chris Evelo
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Bibliography
Barros AG, Liu J, Lemieux GA, Mullaney BC, Ashrafi K; ''Analyses of C. elegans fat metabolic pathways.''; Methods Cell Biol, 2012
PubMed
Europe PMC
Scholia
Srinivasan S; ''Regulation of body fat in Caenorhabditis elegans.''; Annu Rev Physiol, 2015
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
118568
view
12:14, 28 May 2021
DeSl
Annotated some lipids with WP143 counterpart (Human)
118567
view
12:10, 28 May 2021
DeSl
Modified description
118566
view
12:08, 28 May 2021
DeSl
Added another lit. ref
118565
view
12:06, 28 May 2021
DeSl
Added lit ref., cleaned up comments in description
118564
view
12:05, 28 May 2021
DeSl
Merged fatty acyl CoA nodes
118563
view
12:04, 28 May 2021
DeSl
Reconnected all enzymes properly
118562
view
12:00, 28 May 2021
DeSl
Added PW ref.
118561
view
12:00, 28 May 2021
DeSl
Converted all textlabels to DataNodes
118474
view
15:20, 27 May 2021
Ziska
Connected lines
118163
view
10:41, 25 May 2021
Eweitz
Modified title
68482
view
20:47, 5 July 2013
MaintBot
Updated to 2013 gpml schema
67717
view
11:53, 26 June 2013
Ddigles
Ontology Term : 'triacylglycerol biosynthetic pathway' added !
40635
view
19:57, 1 March 2011
MaintBot
Removed redundant pathway information and comments
21125
view
11:30, 14 November 2008
MaintBot
[[Pathway:Caenorhabditis elegans:Triacylglyceride Synthesis BiGCaT]] moved to [[Pathway:WP212]]: Moved to stable identifier
8582
view
14:04, 7 January 2008
MaintBot
Added to category $category
8580
view
14:03, 7 January 2008
Evelo
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AGPAT2
GeneProduct
AGPAT3
GeneProduct
AGPAT4
GeneProduct
AYR1
GeneProduct
Yeast
C05D11.7
GeneProduct
175910 (Entrez Gene)
C46C11.1
GeneProduct
180737 (Entrez Gene)
DGAT1
GeneProduct
Degradation Path
Pathway
Diacylglycerol
Metabolite
Dihydroxyacetone phosphate
Metabolite
16108 (ChEBI)
Dihydroxyacetonephosphate
Metabolite
16108 (ChEBI)
F53C3.13
GeneProduct
173734 (Entrez Gene)
Fatty Acid Synthesis
Pathway
WP38 (WikiPathways)
Fatty Acyl CoA
Metabolite
Fatty acyl CoA
Metabolite
GK2
GeneProduct
Glycerol-3-phosphate
Metabolite
15978 (ChEBI)
Glycerol
Metabolite
17754 (ChEBI)
K11H3.1
GeneProduct
176399 (Entrez Gene)
LIPC
GeneProduct
LPL
GeneProduct
Lysophosphatic Acid
Metabolite
MGAT3
GeneProduct
Monoacylglycerol
Metabolite
PPAP2B
GeneProduct
PPAP2C
GeneProduct
Phosphatic acid
Metabolite
R11F4.1
GeneProduct
173747 (Entrez Gene)
Triacylglycerol
Metabolite
17855 (ChEBI)
Y53G8B.2
GeneProduct
175417 (Entrez Gene)
acl-11
GeneProduct
185044 (Entrez Gene)
acl-2
GeneProduct
179398 (Entrez Gene)
acl-6
GeneProduct
178928 (Entrez Gene)
acl-7
GeneProduct
174916 (Entrez Gene)
acyldihydroxyacetonephosphate
Metabolite
ads-1
GeneProduct
175192 (Entrez Gene)
gly-14
GeneProduct
175453 (Entrez Gene)
gly-20
GeneProduct
179562 (Entrez Gene)
lipase
GeneProduct
179771 (Entrez Gene)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions