S1P receptor signal transduction (Canis familiaris)

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GPCRs similar to S1PS1PR2MAPK3GNAI3GNAI1S1PR3MAPK1PLCB2AKT2GNAI2S1PR1ASAH1PLCB3MAPK6SPHK1PLCB1MAPK4LOC51190MAPK12RACGAP1PIK3C2BS1PR5AKT3MAPK7SPHK2AKT1


Description

No description

Comments

GenMAPP notes 
Representation of Figure 2. from T. Hla, et al. 2001, Science, 294, pg. 1877
GenMAPP remarks 
Right click here for reference.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP26(r20731) with a 96% conversion rate.

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Ontology Terms

 

Bibliography

  1. Hla T, Lee MJ, Ancellin N, Paik JH, Kluk MJ; ''Lysophospholipids--receptor revelations.''; Science, 2001 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
118659view15:18, 31 May 2021DeSlOntology Term : 'signaling pathway' added !
118658view15:18, 31 May 2021DeSlOntology Term : 'G protein mediated signaling pathway' added !
118657view15:17, 31 May 2021DeSlConnected last unconnected line
118656view15:16, 31 May 2021DeSlAdded description from WP26
118655view15:15, 31 May 2021DeSlCleaned up comments in description
118654view15:14, 31 May 2021DeSlConverted top complex to group, according to lit. ref.
118653view15:12, 31 May 2021DeSlUpdated title according to WP26
118652view15:12, 31 May 2021DeSlRedrawn, structured, converted complexes to groups, as in original (WP26)
87662view08:55, 25 July 2016LindarieswijkOntology Term : 'sphingosine 1-phosphate signaling pathway' added !
68536view22:21, 5 July 2013MaintBotUpdated to 2013 gpml schema
40692view21:50, 1 March 2011MaintBotRemoved redundant pathway information and comments
31808view12:20, 14 August 2009MaintBotFixed group labels
30767view23:14, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1GeneProduct490878 (Entrez Gene)
AKT2GeneProduct449021 (Entrez Gene)
AKT3GeneProduct442964 (Entrez Gene)
ASAH1GeneProduct482897 (Entrez Gene)
GNAI1GeneProduct478227 (Entrez Gene)
GNAI2GeneProduct442957 (Entrez Gene)
GNAI3GeneProduct611810 (Entrez Gene)
LOC51190GeneProduct
MAPK12GeneProduct607023 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK4GeneProduct491690 (Entrez Gene)
MAPK6GeneProduct478311 (Entrez Gene)
MAPK7GeneProduct489532 (Entrez Gene)
PIK3C2BGeneProduct478938 (Entrez Gene)
PLCB1GeneProduct485773 (Entrez Gene)
PLCB2GeneProduct487491 (Entrez Gene)
PLCB3GeneProduct476034 (Entrez Gene)
RACGAP1GeneProduct486549 (Entrez Gene)
S1PR1GeneProduct490138 (Entrez Gene)
S1PR2GeneProduct484959 (Entrez Gene)
S1PR3GeneProduct484199 (Entrez Gene)
S1PR5GeneProduct610828 (Entrez Gene)
SPHK1GeneProduct483329 (Entrez Gene)
SPHK2GeneProduct484401 (Entrez Gene)

Annotated Interactions

No annotated interactions
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