BMP signaling pathway (Danio rerio)

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1binds BMP-2 and BMP-4?degradation of Smad1 and Smad5BMP ligandsbinds BMP-2 and BMP-4ZF marker genesGata genesputative Xenopus direct bmp targetsdanio rerio bmp targetsBMP target genesbmpr1b#snip1bmp1b/tolloidfollistatin-like 1bmpr2#goosecoidbmp1a/tolloidcrim1bmp7/snailhouse (snh)follistatindeltaNP63/tp73l#prdcbmp15#deltaNP63/tp73l#gata4bmp5#bmpr2#bmpr1ab#bmp2b/swirl(swr)bmp2afollistatin likenoggin3tolloid-like 1/mini fin (mfn)noggin2snai1abmp6Crimtwsg1adeltaNP63/tp73lsmad4#bmper#voxid3smad1#acvr2b#bmpr1abmp2bmsx btwsg1b#smad6#deltaNP63/tp73l#tbx2a#acvrl1/violet beauregarde (vbg)msx eventbmp4rack1 (gnb2l1)admp#smad1acvr2b#snai2acvr1/lost a fin (laf)bmp8#kheper/zfhx1gremlin 1bambismad6smad5/somitabun (sbn)gata2hrbmsx apcca#smad4#bambisnai1b#follistatinmsx cbmp4gata3bmp5lsmurf-1(WWP1)deltaNP63/tp73l#chordin/dino(din)bmpr1b#Ubiquitin carrier proteinsmad6#smad1Nucleoporin like protein RABnoggin3prdcsmad8bmp3#Rbl15#smurf2msx egata1/vlad tepes (vlt)gata5smad7follistatin 2#bmp1l#Rbl15bmp5#tbx2bsmad4#bmp1b/tolloidgremlin 1bmp1abambigata6bmp7msx dnoggin1bmp1bgata2


Description

No description

Comments

GenMAPP notes 
* = not present in GenMAPP gene database
GenMAPP remarks 
# = not represented in Agilent zebrafish 22K oligochip

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Ontology Terms

 

Bibliography

  1. Krens SF, Corredor-Adamez M, He S, Snaar-Jagalska BE, Spaink HP; ''ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis.''; BMC Genomics, 2008 PubMed Europe PMC Scholia
  2. Liu X, Wang Q, Meng A; ''Detection of Smad Signaling in Zebrafish Embryos.''; Methods Mol Biol, 2016 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118479view05:38, 28 May 2021EgonwReplaced UniGene IDs with Ensembl IDs
118478view05:33, 28 May 2021EgonwReplaced UniGene IDs with Ensembl IDs from the comments
111797view15:07, 7 September 2020LaurentFixed interactions
111762view19:04, 5 September 2020EgonwCorrected the data source
109427view08:48, 17 March 2020L DupuisChanged interaction line to graphical line
101827view09:21, 12 November 2018EgonwReplaced old Uniprot data sources with the new ones.
95492view13:07, 18 December 2017DeSlRemoved "last modified" item
95490view12:25, 18 December 2017DeSlModified description
95489view12:21, 18 December 2017DeSlChanged IDs from Dr-database which didn't map to BridgeDB with Uniprot/ensemble.
89465view13:14, 15 September 2016Mkutmonremove space in ontology term id
87369view09:56, 22 July 2016MaintBotadded missing graphids
84689view20:18, 15 March 2016Khanspersconnected interactions and updated xrefs
84688view20:12, 15 March 2016KhanspersPeriodical save, work in progress
84687view20:01, 15 March 2016KhanspersQuick edit to datanode annotation or property
84686view19:59, 15 March 2016Khanspersremoved hash marks
68610view03:50, 6 July 2013MaintBotUpdated to 2013 gpml schema
67097view10:06, 26 June 2013Christine ChichesterOntology Term : 'Bone morphogenetic proteins signaling pathway' added !
58784view22:44, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40771view22:14, 1 March 2011MaintBotRemoved redundant pathway information and comments
29890view11:17, 9 June 2009Thomasupdated ensembl references
29184view18:25, 9 April 2009KhanspersChanges pathway name: removed "zebrafish"
21123view11:30, 14 November 2008MaintBot[[Pathway:Danio rerio:BMP Signaling]] moved to [[Pathway:WP211]]: Moved to stable identifier
16287view20:41, 17 June 2008Khanspers[[Pathway:Danio rerio:Dr BMP-signaling]] moved to [[Pathway:Danio rerio:BMP Signaling]]: Removed species code prefix
15416view23:50, 27 May 2008KhanspersPeriodical save, work in progress
14271view07:10, 22 May 2008SFGKrensModified categories
14043view08:16, 21 May 2008SFGKrensNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CrimGeneProductDr.87739 (UniGene)
Nucleoporin like protein RABGeneProduct393560 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000021158
Rbl15#GeneProductDr.48738 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000034837
Rbl15GeneProduct445053 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000034837
Ubiquitin carrier proteinGeneProduct565498 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000047452
acvr1/lost a fin (laf)GeneProduct30615 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000017977
acvr2b#GeneProduct30457 (Entrez Gene)
acvr2b#GeneProductENSDARG00000041516 (Ensembl)
acvrl1/violet beauregarde (vbg)GeneProduct266753 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000043462
admp#GeneProduct140619 (Entrez Gene)
bambiGeneProduct431736 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000078899
bambiGeneProduct83496 (Entrez Gene)
bmp15#GeneProductDr.7003 (UniGene)
bmp1a/tolloidGeneProductDr.80162 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000033284
bmp1aGeneProductDr.76758 (UniGene)
bmp1b/tolloidGeneProduct335826 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000059795
bmp1b/tolloidGeneProduct559877 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000059795
bmp1bGeneProduct559877 (Entrez Gene)
bmp1l#GeneProduct30204 (Entrez Gene)
bmp2aGeneProduct30631 (Entrez Gene)
bmp2b/swirl(swr)GeneProductDr.568 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000060734
bmp2bGeneProductDr.568 (UniGene)
bmp3#GeneProduct335252 (Entrez Gene)
bmp4GeneProduct30612 (Entrez Gene)
bmp5#GeneProduct394026 (Entrez Gene)
bmp5lGeneProduct337711 (Entrez Gene)
bmp6GeneProductDr.85164 (UniGene)
bmp7/snailhouse (snh)GeneProduct30584 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000016472
bmp7GeneProductDr.77644 (UniGene)
bmp8#GeneProduct378445 (Entrez Gene)
bmper#GeneProductDr.38460 (UniGene)
bmpr1aGeneProduct58145 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000026768
bmpr1ab#GeneProductDr.7989 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000066309
bmpr1b#GeneProduct30742 (Entrez Gene)
bmpr1b#GeneProductENSDARG00000005600 (Ensembl)
bmpr2#GeneProduct555655 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000002334
bmpr2#GeneProduct562822 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000056764
chordin/dino(din)GeneProductDr.75804 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000045110
crim1GeneProduct404210 (Entrez Gene)
deltaNP63/tp73l#GeneProduct325581 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000065285
deltaNP63/tp73l#GeneProduct335185 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000065137
deltaNP63/tp73lGeneProduct260407 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000065137
follistatin 2#GeneProductDr.76601 (Other) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000080772
follistatin likeGeneProductDr.4964 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000080772
follistatin-like 1GeneProductDr.4964 (UniGene)
follistatinGeneProduct30235 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000051065
follistatinGeneProduct557352 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000034851
gata1/vlad tepes (vlt)GeneProductDr.355 (UniGene)
gata2GeneProduct30480 (Entrez Gene)
gata3GeneProduct30458 (Entrez Gene)
gata4GeneProduct30483 (Entrez Gene)
gata5GeneProduct30482 (Entrez Gene)
gata6GeneProduct58076 (Entrez Gene)
goosecoidGeneProductDr.289 (UniGene)
gremlin 1GeneProduct405778 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000076092
hrbGeneProductDr.1483 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000043960
id3GeneProduct246093 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000021064
kheper/zfhx1GeneProductDr.78569 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000047724
msx aGeneProduct30528 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000017825
msx bGeneProduct30511 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000008486
msx cGeneProduct30526 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000014176
msx dGeneProduct30531 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000003441
msx eGeneProduct30527 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000002232
msx eGeneProductDr.75086 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000002232
noggin1GeneProductDr.78473 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000081766
noggin2GeneProductDr.8123 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000063231
noggin3GeneProduct30173 (Entrez Gene)
pcca#GeneProduct437019 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000034097
prdcGeneProduct378455 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000024960
prdcGeneProduct550399 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000024960
rack1 (gnb2l1)GeneProduct30722 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000061001
smad1#GeneProduct323405 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000033566
smad1GeneProduct30628 (Entrez Gene)
smad4#GeneProduct30640 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000035478
smad4#GeneProductDr.8327 (UniGene)
smad4#GeneProductENSDARG00000045094 (Ensembl)
smad5/somitabun (sbn)GeneProduct30641 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000054175
smad6#GeneProduct116992 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000014508
smad6#GeneProductDr.30811 (UniGene)
smad6GeneProductENSDARG00000031763 (Ensembl)
smad7GeneProductDr.52521 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000024277
smad8GeneProductDr.75542 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000028618
smurf-1(WWP1)GeneProductDr.76814 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000004923
smurf2GeneProductDr.77630 (UniGene)
snai1aGeneProductDr.75079 (UniGene)
snai1b#GeneProductDr.625 (UniGene)
snai2GeneProductDr.75349 (UniGene)
snip1GeneProduct474374 (Entrez Gene)
tbx2a#GeneProduct30247 (Entrez Gene)
tbx2bGeneProduct30253 (Entrez Gene)
tolloid-like 1/mini fin (mfn)GeneProduct474335 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000054472
twsg1aGeneProductDr.45891 (UniGene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000049963
twsg1b#GeneProduct259304 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000059299
ventGeneProduct64810 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000017456
voxGeneProduct64807 (Entrez Gene) http://www.ensembl.org/Danio_rerio/searchview?_q=ENSDART00000008176

Annotated Interactions

No annotated interactions
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