Ebola virus infection in host (Homo sapiens)

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ITGA2CLEC10AASGR1ADAM17ICAM2ICAM3RHOBCD209CLEC4MHAVCR1MHC1GAS6TYRO3ITGA3ITGA4ITGA5ITGA1ITGA6ITGB1ITGB3BST2RAB7ACell MembraneRAB5ANPC1NPC2CTSBCTSLLysosomeNucleusAXLMERTKIKBKEIRF7KPNA1CLEC4GVP35VP24IQGAP1VP40TBK1EBOLAC1QBPTLR4TIMD4VIRUS'RNATPCN2TSG101STAT1NEDD4SOCS3PIK3RCDC42Trans-InfectionMHC2MacropinocytosisIRF3Interferon ResponseExit of Secreted GPAssembly and BuddingCLATHRINITGAVsGPCytokine Signal1CLEC6AMBL2GP1,241CAVEOLINFOLR1RHOC4ssGPTranscription, Traduction and ReplicationVP30Cell AdhesionImmune Surveillance LNPLopes, E. N. 2017EndosomeFusion toCleave EnvelopeFusion to Ebola's GPChanges the pHGPRAC1EGFRExit byAKT1MFGE8CD300APRKRADDX58HAVCR2IL4DAB2IPTFAP2ARAB9AEIF2AK2EIF2S1VPS33AVPS18VPS39VPS41VPS11VPS16NFKBVPS4AdsRNAEPS15ERKRASA2RHOAGELSOLIN2ACTINActin CytoskeletonEP300CREBBPCDC44F-ACTINFILAMINPAK133TIAM1VAV2IGF1RCLTCCLTACLTBCLTCL1CAV1CAV2CAV3PIK3R1PIK3CAPIK3CBPIK3CDPIK3R3PIK3R2IsoformsPP1LC8TOP1FLNAFLNBFLNCGSNSCINMAPK1MAPK3NFKB1NFKB2RELRELAACTN1ACTN4ACTBACTG1HLA-AHLA-BHLA-CHLA-DMAHLA-DMBHLA-DOAHLA-DOBHLA-DPA1HLA-EHLA-FHLA-GHLA-DPB1HLA-DQA1HLA-DQA2HLA-DQB1HLA-DQB2HLA-DRAHLA-DRB1HLA-DRB3HLA-DRB4HLA-DRB566342234313173343321313131966137182019136421172127262117234137131361366632626613131362206661322422243222262226666261361010202110101010101010101010101010101010510101010131344333342342342642564622264RELB13EBOLAEBOLAPtdSerGP3


Description

Study of Ebola interaction with human proteins. The corse of the representation it occurred by left to right. The numbers on circles are relatived study of the evolutionary levels (provisional data).

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
120623view22:45, 20 December 2021KhanspersModified title
118435view14:40, 27 May 2021Mkutmonfixed publication refs
117706view12:26, 22 May 2021EweitzModified title
101851view14:32, 13 November 2018Elisson nl
101850view14:30, 13 November 2018Elisson nlInteractions correction
98605view20:09, 20 September 2018Elisson nlModified description
98604view19:52, 20 September 2018Elisson nlModified description
98603view19:48, 20 September 2018Elisson nlModification in interactions
98602view19:09, 20 September 2018Elisson nlAnnotated interaction
98332view04:31, 23 August 2018Elisson nlModified description
98331view04:08, 23 August 2018Elisson nlReferences Accentuation Correction
98330view03:54, 23 August 2018Elisson nlReferences Changed
98292view15:35, 16 August 2018DeSlAdded last missing IDs, coloured MHC1 and 2 subunits for clarity 9couldn't find a ID for these groups). Also added a lit. reference describing the effect of LC8 on VP35
98291view15:17, 16 August 2018DeSlAdded more identifiers.
98290view14:57, 16 August 2018DeSlModified description
97372view19:31, 11 May 2018Elisson nlNew References
97362view20:19, 10 May 2018Elisson nlReferences
97361view19:57, 10 May 2018Elisson nlReferences
97360view19:37, 10 May 2018Elisson nlReferences
97357view19:15, 10 May 2018Elisson nlReferences
97356view19:12, 10 May 2018Elisson nlReferences
97353view19:00, 10 May 2018Elisson nlReferences
97351view18:55, 10 May 2018Elisson nlNew References
97327view19:23, 9 May 2018KhanspersOntology Term : 'viral infectious disease' added !
97326view19:22, 9 May 2018KhanspersOntology Term : 'Ebola hemorrhagic fever' added !
97325view19:22, 9 May 2018Khanspersadded xrefs
97170view21:45, 2 May 2018Elisson nlReferences
96845view17:45, 12 April 2018Elisson nlModified description
96805view10:25, 9 April 2018DeSlChanged lines to graphical lines for Ebola virus drawing
96804view10:17, 9 April 2018DeSlAdded IDs from https://www.wikipathways.org/index.php/Pathway:WP4180
96119view02:55, 20 February 2018Elisson nlModified description
96118view02:47, 20 February 2018Elisson nlNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ACTBGeneProductENSG00000075624 (Ensembl)
ACTG1GeneProductENSG00000184009 (Ensembl)
ACTINGeneProduct
ACTN1GeneProductENSG00000072110 (Ensembl)
ACTN4GeneProductENSG00000130402 (Ensembl)
ADAM17GeneProductENSG00000151694 (Ensembl)
AKT1GeneProductENSG00000142208 (Ensembl)
ASGR1GeneProductENSG00000141505 (Ensembl)
AXLGeneProductENSG00000167601 (Ensembl)
BST2GeneProductENSG00000130303 (Ensembl)
C1QBPGeneProductENSG00000108561 (Ensembl)
CAV1GeneProductENSG00000105974 (Ensembl)
CAV2GeneProductENSG00000105971 (Ensembl)
CAV3GeneProductENSG00000182533 (Ensembl)
CAVEOLINGeneProduct
CD209GeneProductENSG00000090659 (Ensembl)
CD300AGeneProductENSG00000167851 (Ensembl)
CDC42GeneProductENSG00000070831 (Ensembl)
CDC44GeneProduct
CLATHRINGeneProduct
CLEC10AGeneProductENSG00000132514 (Ensembl)
CLEC4GGeneProductENSG00000182566 (Ensembl)
CLEC4MGeneProductENSG00000104938 (Ensembl)
CLEC6AGeneProductENSG00000205846 (Ensembl)
CLTAGeneProductENSG00000122705 (Ensembl)
CLTBGeneProductENSG00000175416 (Ensembl)
CLTCGeneProductENSG00000141367 (Ensembl)
CLTCL1GeneProductENSG00000070371 (Ensembl)
CREBBPGeneProductENSG00000005339 (Ensembl)
CTSBGeneProductENSG00000164733 (Ensembl)
CTSLGeneProductENSG00000135047 (Ensembl)
DAB2IPGeneProductENSG00000136848 (Ensembl)
DDX58GeneProductENSG00000107201 (Ensembl)
EGFRGeneProductENSG00000146648 (Ensembl)
EIF2AK2GeneProductENSG00000055332 (Ensembl)
EIF2S1GeneProductENSG00000134001 (Ensembl)
EP300GeneProductENSG00000100393 (Ensembl)
EPS15GeneProductENSG00000085832 (Ensembl)
ERKGeneProduct
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FLNAGeneProductENSG00000196924 (Ensembl)
FLNBGeneProduct
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GELSOLINGeneProductA0A0A0MS51 (Uniprot-TrEMBL)
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HLA-DQA1GeneProductENSG00000196735 (Ensembl)
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VAV2GeneProductENSG00000160293 (Ensembl)
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VPS39GeneProductENSG00000166887 (Ensembl)
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VPS4AGeneProductENSG00000132612 (Ensembl)

Annotated Interactions

View all...
SourceTargetTypeDatabase referenceComment
CTSBEBOLAArrow2 (Other) PUBMED
CTSLEBOLAArrow3 (Other) PUBMED
EBOLANPC1Arrow4 (Other) PUBMED
ERK1 (Other) PUBMED
F-ACTIN7 (Other) PUBMED
FILAMIN6 (Other) PUBMED
NPC2NPC1Arrow5 (Other) PUBMED
PAK18 (Other) PUBMED
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP4217"