Peroxiredoxin 2 induced ovarian failure (Mus musculus)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Park SJ, Kim JH, Lee DG, Kim JM, Lee DS; ''Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice.''; Free Radic Biol Med, 2018 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	110293	view	14:20, 2 May 2020	Egonw	Replaced secondary ChEBI identifiers with a primary identifiers.
	110230	view	14:26, 27 April 2020	Egonw	Updated the data source.
	110070	view	08:45, 16 April 2020	Fehrhart	Ontology Term : 'c-Jun N-terminal kinases MAPK signaling pathway' added !
	110069	view	08:45, 16 April 2020	Fehrhart	Added reference and some graphical adjustments
	110068	view	08:43, 16 April 2020	Fehrhart	Modified description
	109438	view	12:54, 17 March 2020	Fehrhart	Ontology Term : 'ovarian dysfunction' added !
	109437	view	12:54, 17 March 2020	Fehrhart	Ontology Term : 'signaling pathway' added !
	109250	view	11:56, 2 March 2020	Laurent	Modified title
	109233	view	12:10, 1 March 2020	Bas Lahaije	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
3Beta-HSD	Protein	E9PXG7 (Uniprot-TrEMBL)
Bax	GeneProduct	ENSMUSG00000003873 (Ensembl)
CYP11A1	Protein	Q9QZ82 (Uniprot-TrEMBL)	Mitochondrial
Caspase-3	Protein	A0A1B0GRX1 (Uniprot-TrEMBL)
Cytochrome c	Protein	P62897 (Uniprot-TrEMBL)	Somatic
Estradiol-17beta	Metabolite	CHEBI:4864 (ChEBI)
JNK	Protein	ENSMUSP00000023291 (Ensembl Mouse)
PARP	Metabolite	CHEBI:62913 (ChEBI)
Peroxiredoxin-2	Protein	Q61171 (Uniprot-TrEMBL)
Progesterone	Metabolite	CHEBI:45786 (ChEBI)
Reactive oxygen species	Metabolite	CHEBI:26523 (ChEBI)
StAR	Protein	P51557 (Uniprot-TrEMBL)	Mitichondrial Type your comment here

Annotated Interactions

No annotated interactions