N-glycan biosynthesis (Ovis aries)

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DDOSDolicholBeta-D-MannosyldiacetylchitobiosyldiphosphodolicholALG12(Glc)3 (GlcNAc)2 (Man)9 (PP-Dol)1MGAT4A(Glc)1 (GlcNAc)2 (Man)9 (PP-Dol)1RPN1ALG13MAN1A1N-Acetyl-D-glucosaminyldiphosphodolicholMAN1C1MGAT3(GlcNAc)2 (Man)3 (PP-Dol)1LOC114113140ALG9GDP-mannoseALG2Dolichol KinaseRPN2Dolichyl Beta-D-Glucosyl PhosphateMGAT1MOGS(GlcNAc)5 (Man)3 (Asn)1(GlcNAc)2 (Man)4 (PP-Dol)1B4GALT1Dolichyl phosphate D-mannoseVarious types of N-glycan biosynthesis(Gal)2 (GlcNAc)4 (LFuc)1 (Man)3 (Asn)1(GlcNAc)2 (Man)7 (PP-Dol)1MGAT4BST6GAL1 N,N'-Chitobiosyldiphosphodolichol(GlcNAc)2 (Man)5 (PP-Dol)1Polyprenol ReductaseGlycosaminoglycan biosynthesis - Keratan sulfateGANABMAN2A2B4GALT3DPAGT1STT3BALG10ALG5ALG3L-Asparagine(Glc)1 (GlcNAc)2 (Man)9 (Asn)1(GlcNAc)2 (Man)6 (PP-Dol)1DAD1DPM1(Gal)2 (GlcNAc)4 (LFuc)1 (Man)3 (Neu5Ac)2 (Asn)1MGAT5B(GlcNAc)3 (Man)5 (Asn)1ALG14Ditrans,polycis-polyprenolDolichyl PhosphateTUSC3MGAT2MGAT4D(GlcNAc)2 (Man)2 (PP-Dol)1ALG11(GlcNAc)3 (Man)3 (Asn)1MAN1A2DMP2(GlcNAc)2 (Man)8 (PP-Dol)1ST6GAL2STT3A(GlcNAc)2 (Man)8 (Asn)1(Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1Terpenoid Backbone Biosynthesis(GlcNAc)2 (Man)9 (Asn)1ALG8ALG1(Glc)2 (GlcNAc)2 (Man)9 (Asn)1(GlcNAc)2 (Man)5 (Asn)1Dolichyl DiphosphateALG6DMP3FUT8(GlcNAc)4 (LFuc)1 (Man)3 (Asn)1(GlcNAc)5 (Man)3 (Asn)1DolichyldiphosphataseMGAT4CMGAT5(Glc)3 (GlcNAc)2 (Man)9 (Asn)1Fructose and Mannose Metabolism(GlcNAc)4 (Man)3 (Asn)1(GlcNAc)6 (Man)3 (Asn)1(GlcNAc)7 (Man)3 (Asn)1(GlcNAc)2 (Man)9 (PP-Dol)1ALG2ALG11ALG9GANABMAN1B1


Description

N-Glycan Biosynthesis - Ovis Aries (Sheep)

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Ontology Terms

 

Bibliography

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  1. Oriol R, Martinez-Duncker I, Chantret I, Mollicone R, Codogno P; ''Common origin and evolution of glycosyltransferases using Dol-P-monosaccharides as donor substrate.''; Mol Biol Evol, 2002 PubMed Europe PMC Scholia
  2. Roth J; ''Protein N-glycosylation along the secretory pathway: relationship to organelle topography and function, protein quality control, and cell interactions.''; Chem Rev, 2002 PubMed Europe PMC Scholia
  3. Breitling J, Aebi M; ''N-linked protein glycosylation in the endoplasmic reticulum.''; Cold Spring Harb Perspect Biol, 2013 PubMed Europe PMC Scholia
  4. Cumming DA; ''Chapter 14: Pathways and functions of mammalian protein glycosylation''; Gene Transfer and Expression in Mammalian Cells, 2003 PubMed Europe PMC Scholia
  5. Cipollo JF, Trimble RB, Chi JH, Yan Q, Dean N; ''The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum.''; J Biol Chem, 2001 PubMed Europe PMC Scholia
  6. Thiel C, Schwarz M, Peng J, Grzmil M, Hasilik M, Braulke T, Kohlschütter A, von Figura K, Lehle L, Körner C; ''A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis.''; J Biol Chem, 2003 PubMed Europe PMC Scholia
  7. O'Reilly MK, Zhang G, Imperiali B; ''In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis.''; Biochemistry, 2006 PubMed Europe PMC Scholia
  8. Frank CG, Aebi M; ''ALG9 mannosyltransferase is involved in two different steps of lipid-linked oligosaccharide biosynthesis.''; Glycobiology, 2005 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
128708view22:13, 20 February 2024EgonwFixed a datasource
128707view22:11, 20 February 2024EgonwCorrect data source
125501view20:40, 21 February 2023AlexanderPicofixed invalid citation xref
122596view10:53, 20 April 2022EweitzModified description
122595view10:34, 20 April 2022EweitzModified description
122592view10:28, 20 April 2022EweitzModified title
122558view02:15, 16 April 2022EweitzModified title
122088view15:31, 10 March 2022ChristeldeVriesModified description
122087view15:31, 10 March 2022ChristeldeVriesModified description
122086view14:30, 10 March 2022ChristeldeVriesOntology Term : 'lipid metabolic pathway' added !
122085view14:22, 10 March 2022ChristeldeVriesOntology Term : 'glycan metabolic pathway' added !
122084view14:20, 10 March 2022ChristeldeVriesOntology Term : 'N-linked glycan biosynthetic pathway' added !
122083view14:16, 10 March 2022ChristeldeVriesFixed the references using the .bat file
122018view10:06, 9 March 2022ChristeldeVriesAdded identifier of (GlcNAc)2 (Man)5 (Asn)1. Improved layout for a better overview and readability.
121645view10:59, 23 February 2022ChristeldeVriesUpdated the references
121605view22:10, 21 February 2022EgonwModified title
121604view22:09, 21 February 2022EgonwUpdated the species to sheep
121447view14:33, 17 February 2022ChristeldeVriesChanged links to other pathways
121390view09:42, 17 February 2022ChristeldeVriesNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
N,N'-ChitobiosyldiphosphodolicholMetaboliteG00002 (KEGG Glycan)
(Gal)2 (GlcNAc)4 (LFuc)1 (Man)3 (Asn)1MetaboliteG00017 (KEGG Glycan)
(Gal)2 (GlcNAc)4 (LFuc)1 (Man)3 (Neu5Ac)2 (Asn)1MetaboliteG00018 (KEGG Glycan)
(Glc)1 (GlcNAc)2 (Man)9 (Asn)1MetaboliteG00010 (KEGG Drug)
(Glc)1 (GlcNAc)2 (Man)9 (PP-Dol)1MetaboliteG10598 (KEGG Glycan)
(Glc)2 (GlcNAc)2 (Man)9 (Asn)1MetaboliteG00171 (KEGG Glycan)
(Glc)2 (GlcNAc)2 (Man)9 (PP-Dol)1MetaboliteG10599 (KEGG Glycan)
(Glc)3 (GlcNAc)2 (Man)9 (Asn)1MetaboliteG00009 (KEGG Glycan)
(Glc)3 (GlcNAc)2 (Man)9 (PP-Dol)1MetaboliteG00008 (KEGG Glycan)
(GlcNAc)2 (Man)2 (PP-Dol)1MetaboliteG00004 (KEGG Glycan) Sometimes referred to as: - Alpha-D-Mannosyl-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol
(GlcNAc)2 (Man)3 (PP-Dol)1MetaboliteG00005 (KEGG Glycan)
(GlcNAc)2 (Man)4 (PP-Dol)1MetaboliteG10526 (KEGG Glycan)
(GlcNAc)2 (Man)5 (Asn)1Metabolite
(GlcNAc)2 (Man)5 (PP-Dol)1MetaboliteG00006 (KEGG Glycan) Sometimes referred to as: - (alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol
(GlcNAc)2 (Man)6 (PP-Dol)1MetaboliteG10595 (KEGG Glycan)
(GlcNAc)2 (Man)7 (PP-Dol)1MetaboliteG10596 (KEGG Glycan)
(GlcNAc)2 (Man)8 (Asn)1MetaboliteG10694 (KEGG Glycan)
(GlcNAc)2 (Man)8 (PP-Dol)1MetaboliteG10597 (KEGG Glycan)
(GlcNAc)2 (Man)9 (Asn)1MetaboliteG00011 (KEGG Glycan)
(GlcNAc)2 (Man)9 (PP-Dol)1MetaboliteG00007 (KEGG Glycan)
(GlcNAc)3 (Man)3 (Asn)1MetaboliteG00014 (KEGG Glycan)
(GlcNAc)3 (Man)5 (Asn)1MetaboliteG00013 (KEGG Glycan)
(GlcNAc)4 (LFuc)1 (Man)3 (Asn)1MetaboliteG00016 (KEGG Glycan)
(GlcNAc)4 (Man)3 (Asn)1MetaboliteG00015 (KEGG Glycan)
(GlcNAc)5 (Man)3 (Asn)1MetaboliteG00019 (KEGG Glycan)
(GlcNAc)5 (Man)3 (Asn)1MetaboliteG00020 (KEGG Glycan)
(GlcNAc)6 (Man)3 (Asn)1MetaboliteG00021 (KEGG Glycan)
(GlcNAc)7 (Man)3 (Asn)1MetaboliteG00022 (KEGG Glycan)
ALG10GeneProductENSOARG00000019292 (Ensembl) Sometimes referred to as:

- dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase - alpha-1,2-glucosyltransferase

- ALG10 alpha-1,2-glucosyltransferase
ALG11GeneProductXP_004012140 (NCBI Protein) Sometimes referred to as:

- GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

- Alpha-1,2-mannosyltransferase
ALG12GeneProductENSOARG00000019629 (Ensembl) Sometimes referred to as:

- Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase - Alpha-1,6-mannosyltransferase

- ALG12 alpha-1,6-mannosyltransferase
ALG13GeneProductENSOARG00000017633 (Ensembl) Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform X1.
ALG14GeneProductXP_027828046 (NCBI Protein) Sometimes referred to as:

- UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform X1

- beta-1,4-N-acetylglucosaminyltransferase
ALG1GeneProductENSOARG00000005002 (Ensembl) Sometimes referred to as:

- chitobiosyldiphosphodolichol beta-mannosyltransferase isoform X1 - chitobiosyldiphosphodolichol beta-mannosyltransferase

ALG2GeneProductXP_004004274 (NCBI Protein) Sometimes referred to as:

- alpha-1,3/1,6-mannosyltransferase ALG2

- alpha-1,3/alpha-1,6-mannosyltransferase
ALG3GeneProductENSOARG00000020606 (Ensembl) Sometimes referred to as:

- Alpha-1,3-mannosyltransferase - Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

- ALG3 alpha-1,3- mannosyltransferase
ALG5GeneProductENSOARG00000010275 (Ensembl) Sometimes referred to as:

- ALG5 dolichyl-phosphate beta-glucosyltransferase

- Dolichyl-phosphate beta-glucosyltransferase
ALG6GeneProductENSOARG00000009650 (Ensembl) Sometimes referred to as:

- ALG6 alpha-1,3-glucosyltransferase

- Alpha-1,3-glucosyltransferase
ALG8GeneProductENSOARG00000006601 (Ensembl) Sometimes referred to as:

- Alpha-1,3-glucosyltransferase

- ALG8 alpha-1,3-glucosyltransferase
ALG9GeneProductENSOARG00000014873 (Ensembl)
B4GALT1GeneProductENSOARG00000009544 (Ensembl) Sometimes referred to as: - Beta-1,4-galactosyltransferase 1
B4GALT3GeneProductENSOARG00000009668 (Ensembl) Sometimes referred to as: - Beta-1,4-galactosyltransferase 3
Beta-D-MannosyldiacetylchitobiosyldiphosphodolicholMetaboliteG00003 (KEGG Glycan)
DAD1GeneProductENSOARG00000019440 (Ensembl) Sometimes referred to as:

- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 - Oligosaccharyltransferase complex subunit epsilon

- Defender against cell death 1
DDOSGeneProductENSOARG00000009017 (Ensembl) Sometimes referred to as:

- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

- Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
DMP2ProteinENSOARG00000011136 (Ensembl) Sometimes referred to as:

- Dolichol phosphate-mannose biosynthesis regulatory protein

- Dolichyl-phosphate mannosyltransferase subunit 2
DMP3ProteinENSOARG00000006665 (Ensembl) Sometimes referred to as: - Dolichol-phosphate mannosyltransferase subunit 3
DPAGT1ProteinENSOARG00000013201 (Ensembl) Sometimes referred to as:

- Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 - UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase isoform X1

- ALG7 (=gene)
DPM1ProteinENSOARG00000013988 (Ensembl) Sometimes referred to as: - Dolichol-phosphate mannosyltransferase subunit 1
Ditrans,polycis-polyprenolMetaboliteCHEBI:67132 (ChEBI) In literature also simply refered to as polyprenol.
Dolichol KinaseProteinENSOARG00000019081 (Ensembl) Sometimes referred to as: - DOLK
DolicholMetaboliteCHEBI:16091 (ChEBI)
Dolichyl Beta-D-Glucosyl PhosphateMetaboliteLMPR03080014 (LIPID MAPS) Sometimes referred to as:

- α-(3-methylbut-2-en-1-yl)-ω-{4-[(β-D-glucopyranosyloxy)(hydroxy)phosphoryloxy]-2-methylbutyl}poly[(2E)-2-methylbut-2-ene-1,4-diyl]

- Dolichyl beta-D-glucosyl phosphate
Dolichyl DiphosphateMetaboliteLMPR03090023 (LIPID MAPS) Sometimes referred to as: - Dolichol diphosphate
Dolichyl PhosphateMetaboliteLMPR03080015 (LIPID MAPS) Sometimes referred to as:

- Dolichol phosphate - Dolicholmonophosphate

Dolichyl phosphate D-mannoseMetabolite6598 (PubChem-substance) Sometimes referred to as:

- Dolichyl phosphate D-mannose - Dolichyl D-mannosyl phosphate

- Dolichyl beta-D-mannosyl phosphate
DolichyldiphosphataseProteinXP_027822123 (NCBI Protein) Sometimes referred to as:

- DOLPP1

- Dolichyldiphosphatase 1 isoform X5
FUT8GeneProductENSOARG00000021160 (Ensembl) Sometimes referred to as:

- Fucosyltransferase 8

- Alpha-(1,6)-fucosyltransferase
Fructose and Mannose MetabolismPathwayoas00051 (KEGG Pathway) This pathway can be found in the Kegg database. Here, one can manually adjust the general-species pathway to the Ovis Aries pathway.
GANABGeneProductENSOARG00000015910 (Ensembl) Sometimes referred to as:

- Neutral alpha-glucosidase AB isoform X1 - Mannosyl-oligosaccharide alpha-1,3-glucosidase

- Glucosidase II alpha subunit
GDP-mannoseMetaboliteC00096 (KEGG Compound) Sometimes referred to as:

- GDP mannose - GDP-mannose - GDP-alpha-D-mannose - Guanosine diphosphate mannose

- The α-anomer of GDP-D-mannose
Glycosaminoglycan biosynthesis - Keratan sulfatePathwayoas00533 (KEGG Pathway)
L-AsparagineMetaboliteCHEBI:17196 (ChEBI) Sometimes referred to as "Asn-X-Ser/Thr" because oligosaccharyltransferase (OST) selects the Asn-X-Ser/Thr consensus sequence on polypeptide chains
LOC114113140GeneProductA0A6P7DPQ4 (Uniprot-TrEMBL) Sometimes referred to as:

- Sialyltransferase 1

- Beta-galactoside alpha-2,6-sialyltransferase 1-like
MAN1A1GeneProductENSOARG00000008408 (Ensembl) Sometimes referred to as:

- Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA - Mannosyl-oligosaccharide alpha-1,2-mannosidase - Mannosidase alpha class 1A member 1

- Alpha-1,2-Mannosidase
MAN1A2GeneProductENSOARG00000020315 (Ensembl) Sometimes referred to as:

- Mannosidase alpha class 1A member 2 - Alpha-1,2-Mannosidase - Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

- Mannosyl-oligosaccharide alpha-1,2-mannosidase
MAN1B1GeneProductA0A6P7DSV8 (Uniprot-TrEMBL) Sometimes referred to as:

- Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase isoform X1 - Endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase

- Alpha-1,2-Mannosidase
MAN1C1GeneProductENSOARG00000005906 (Ensembl) Sometimes referred to as:

- Mannosidase alpha class 1C member 1 - Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC isoform X1

- Alpha-1,2-Mannosidase
MAN2A2GeneProductENSOARG00000012575 (Ensembl) Sometimes referred to as:

- Alpha-mannosidase II - Alpha-mannosidase 2x isoform X1

- Mannosidase alpha class 2A member 2
MGAT1GeneProductENSOARG00000016716 (Ensembl) Sometimes referred to as:

- Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

- Alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT2GeneProductENSOARG00000000832 (Ensembl) Sometimes referred to as:

- Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

- Alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT3GeneProductA0A6P7DZW7 (Uniprot-TrEMBL) Sometimes referred to as:

- Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase

- Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase isoform X3
MGAT4AGeneProductENSOARG00000013496 (Ensembl) Sometimes referred to as:

- alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X2

- alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A
MGAT4BGeneProductENSOARG00000002936 (Ensembl) Sometimes referred to as:

- Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B isoform X1

- Alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B
MGAT4CGeneProductA0A6P7DXD1 (Uniprot-TrEMBL) Sometimes referred to as:

- MGAT4 family member C - Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

- Alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C
MGAT4DGeneProductENSOARG00000012558 (Ensembl) Sometimes referred to as:

- MGAT4 family member D - alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B

- alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D
MGAT5BGeneProductENSOARG00000006412 (Ensembl) Sometimes referred to as:

- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B isoform X1 - Mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

- alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
MGAT5GeneProductENSOARG00000011436 (Ensembl) Sometimes referred to as:

- Alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

- Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
MOGSGeneProductENSOARG00000012692 (Ensembl) Sometimes referred to as: - Mannosyl-oligosaccharide glucosidase
N-Acetyl-D-glucosaminyldiphosphodolicholMetaboliteG00001 (KEGG Compound)
Polyprenol ReductaseProteinENSOARG00000001390 (Ensembl) Also referred to as:

- Steroid 5 alpha-reductase 3 - 3-oxo-5-alpha-steroid 4-dehydrogenase 3 - polyprenol reductase isoform X3

From gene:

- SRD5A3
RPN1GeneProductXP_027813657 (NCBI Protein) Sometimes referred to as:

- Ribophorin I - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

- Oligosaccharyltransferase complex subunit alpha
RPN2GeneProductENSOARG00000017801 (Ensembl) Sometimes referred to as:

- Ribophorin II - Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X2

- Oligosaccharyltransferase complex subunit delta
ST6GAL1GeneProductENSOARG00000020506 (Ensembl) Sometimes referred to as:

- Beta-galactoside alpha-2,6-sialyltransferase 1

- ST6 beta-galactoside alpha-2,6-sialyltransferase 1
ST6GAL2GeneProductA0A6P7DVZ4 (Uniprot-TrEMBL) Sometimes referred to as:

- Beta-galactoside alpha-2,6-sialyltransferase 2

- Beta-galactoside alpha-2,6-sialyltransferase 2 isoform X1
STT3AGeneProductENSOARG00000011533 (Ensembl) Sometimes referred to as:

- STT3 oligosaccharyltransferase complex catalytic subunit A - dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A isoform X3

- Dolichyl-diphosphooligosaccharide--protein glycotransferase
STT3BGeneProductENSOARG00000014854 (Ensembl) Sometimes referred to as:

- STT3 oligosaccharyltransferase complex catalytic subunit B - dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

- Dolichyl-diphosphooligosaccharide--protein glycotransferase
TUSC3GeneProductENSOARG00000009678 (Ensembl) Sometimes referred to as:

- Tumor suppressor candidate 3 isoform X4 - Oligosaccharyltransferase complex subunit gamma

Terpenoid Backbone BiosynthesisPathwayoas00900 (KEGG Pathway) This pathway can be found in the Kegg database. Here, one can manually adjust the general-species pathway to the Ovis Aries pathway.
Various types of N-glycan biosynthesisPathwayoas00513 (KEGG Pathway) This pathway can be found in the Kegg database. Here, one can manually adjust the general-species pathway to the Ovis Aries pathway.

Annotated Interactions

No annotated interactions

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