Axon guidance (Homo sapiens)

From WikiPathways

(Difference between revisions)
Jump to: navigation, search
(added KEGG pathway as reference)
Current revision (15:59, 20 April 2024) (view source)
(Modified title)
 
Line 1: Line 1:
<?xml version="1.0" encoding="UTF-8"?>
<?xml version="1.0" encoding="UTF-8"?>
-
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Axon Guidance" Organism="Homo sapiens">
+
<Pathway xmlns="http://pathvisio.org/GPML/2013a" Name="Axon guidance" Organism="Homo sapiens">
-
   <Comment></Comment>
+
   <Comment/>
   <Comment Source="WikiPathways-description">Axon Guidance. Pathway took from KEGG (https://www.kegg.jp/entry/map04360)</Comment>
   <Comment Source="WikiPathways-description">Axon Guidance. Pathway took from KEGG (https://www.kegg.jp/entry/map04360)</Comment>
   <BiopaxRef>ann1</BiopaxRef>
   <BiopaxRef>ann1</BiopaxRef>
   <BiopaxRef>ba3</BiopaxRef>
   <BiopaxRef>ba3</BiopaxRef>
-
   <Graphics BoardWidth="2622.5" BoardHeight="3362.5" />
+
   <Graphics BoardWidth="2622.5" BoardHeight="3362.5"/>
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="sa133" Type="Pathway">
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="sa133" Type="Pathway">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1737.5" CenterY="2322.5" Width="220.0" Height="30.0" ZOrder="5" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1737.5" CenterY="2322.5" Width="220.0" Height="30.0" ZOrder="5" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04810" />
+
     <Xref Database="KEGG Pathway" ID="hsa04810"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MAPK signaling pathway" GraphId="sa131" Type="Pathway">
   <DataNode TextLabel="MAPK signaling pathway" GraphId="sa131" Type="Pathway">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1447.5" CenterY="2262.5" Width="180.0" Height="30.0" ZOrder="12" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1447.5" CenterY="2262.5" Width="180.0" Height="30.0" ZOrder="12" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04010" />
+
     <Xref Database="KEGG Pathway" ID="hsa04010"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="DCC" GraphId="sa14" Type="Protein">
   <DataNode TextLabel="DCC" GraphId="sa14" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="555.5" Width="86.0" Height="46.0" ZOrder="16" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="555.5" Width="86.0" Height="46.0" ZOrder="16" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_005215" />
+
     <Xref Database="RefSeq" ID="NM_005215"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LRRC4C" GraphId="sa1" Type="Protein">
   <DataNode TextLabel="LRRC4C" GraphId="sa1" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="960.0" CenterY="180.0" Width="80.0" Height="40.0" ZOrder="20" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="960.0" CenterY="180.0" Width="80.0" Height="40.0" ZOrder="20" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000148948" />
+
     <Xref Database="Ensembl" ID="ENSG00000148948"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CFL1" GraphId="sa100" Type="Protein">
   <DataNode TextLabel="CFL1" GraphId="sa100" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1577.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="21" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1577.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="21" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000172757" />
+
     <Xref Database="Ensembl" ID="ENSG00000172757"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOA" GraphId="sa101" Type="Protein">
   <DataNode TextLabel="RHOA" GraphId="sa101" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1427.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="22" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1427.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="22" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="667" />
+
     <Xref Database="HGNC Accession number" ID="667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLXNA1" GraphId="sa103" Type="Protein">
   <DataNode TextLabel="PLXNA1" GraphId="sa103" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1862.5" Width="80.0" Height="40.0" ZOrder="23" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1862.5" Width="80.0" Height="40.0" ZOrder="23" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000114554" />
+
     <Xref Database="Ensembl" ID="ENSG00000114554"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NRP1" GraphId="sa104" Type="Protein">
   <DataNode TextLabel="NRP1" GraphId="sa104" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1902.5" Width="80.0" Height="40.0" ZOrder="24" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1902.5" Width="80.0" Height="40.0" ZOrder="24" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8829" />
+
     <Xref Database="Entrez Gene" ID="8829"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="L1CAM" GraphId="sa105" Type="Protein">
   <DataNode TextLabel="L1CAM" GraphId="sa105" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1972.5" Width="80.0" Height="40.0" ZOrder="25" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1972.5" Width="80.0" Height="40.0" ZOrder="25" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="P32004" />
+
     <Xref Database="Uniprot-TrEMBL" ID="P32004"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SEMA3A" GraphId="sa106" Type="Protein">
   <DataNode TextLabel="SEMA3A" GraphId="sa106" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="800.0" CenterY="1880.0" Width="80.0" Height="40.0" ZOrder="26" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="800.0" CenterY="1880.0" Width="80.0" Height="40.0" ZOrder="26" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_006080" />
+
     <Xref Database="RefSeq" ID="NM_006080"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FES" GraphId="sa107" Type="Protein">
   <DataNode TextLabel="FES" GraphId="sa107" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1912.5" Width="80.0" Height="40.0" ZOrder="27" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1912.5" Width="80.0" Height="40.0" ZOrder="27" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002005" />
+
     <Xref Database="RefSeq" ID="NM_002005"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FYN" GraphId="sa108" Type="Protein">
   <DataNode TextLabel="FYN" GraphId="sa108" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1962.5" Width="80.0" Height="40.0" ZOrder="28" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1962.5" Width="80.0" Height="40.0" ZOrder="28" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FYN" />
+
     <Xref Database="HGNC" ID="FYN"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CDK5" GraphId="sa109" Type="Protein">
   <DataNode TextLabel="CDK5" GraphId="sa109" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="1962.5" Width="80.0" Height="40.0" ZOrder="29" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="1962.5" Width="80.0" Height="40.0" ZOrder="29" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="CDK5" />
+
     <Xref Database="HGNC" ID="CDK5"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLCG1" GraphId="sa11" Type="Protein">
   <DataNode TextLabel="PLCG1" GraphId="sa11" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1097.5" CenterY="502.5" Width="80.0" Height="40.0" ZOrder="30" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1097.5" CenterY="502.5" Width="80.0" Height="40.0" ZOrder="30" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9065" />
+
     <Xref Database="HGNC Accession number" ID="9065"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="DPYSL5" GraphId="sa110" Type="Protein">
   <DataNode TextLabel="DPYSL5" GraphId="sa110" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1427.5" CenterY="1892.5" Width="80.0" Height="40.0" ZOrder="31" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1427.5" CenterY="1892.5" Width="80.0" Height="40.0" ZOrder="31" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q9BPU6" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q9BPU6"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="DPYSL2" GraphId="sa111" Type="Protein">
   <DataNode TextLabel="DPYSL2" GraphId="sa111" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1427.5" CenterY="1932.5" Width="80.0" Height="40.0" ZOrder="32" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1427.5" CenterY="1932.5" Width="80.0" Height="40.0" ZOrder="32" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_001386" />
+
     <Xref Database="RefSeq" ID="NM_001386"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLXNB2" GraphId="sa113" Type="Protein">
   <DataNode TextLabel="PLXNB2" GraphId="sa113" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2112.5" Width="80.0" Height="40.0" ZOrder="33" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2112.5" Width="80.0" Height="40.0" ZOrder="33" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9104" />
+
     <Xref Database="HGNC Accession number" ID="9104"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SEMA4F" GraphId="sa114" Type="Protein">
   <DataNode TextLabel="SEMA4F" GraphId="sa114" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="747.5" CenterY="2112.5" Width="80.0" Height="40.0" ZOrder="34" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="747.5" CenterY="2112.5" Width="80.0" Height="40.0" ZOrder="34" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="10734" />
+
     <Xref Database="HGNC Accession number" ID="10734"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SEMA5B" GraphId="sa115" Type="Protein">
   <DataNode TextLabel="SEMA5B" GraphId="sa115" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="750.0" CenterY="2165.0" Width="80.0" Height="40.0" ZOrder="35" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="750.0" CenterY="2165.0" Width="80.0" Height="40.0" ZOrder="35" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="54437" />
+
     <Xref Database="Entrez Gene" ID="54437"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SEMA6C" GraphId="sa116" Type="Protein">
   <DataNode TextLabel="SEMA6C" GraphId="sa116" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="750.0" CenterY="2205.0" Width="80.0" Height="40.0" ZOrder="36" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="750.0" CenterY="2205.0" Width="80.0" Height="40.0" ZOrder="36" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000143434" />
+
     <Xref Database="Ensembl" ID="ENSG00000143434"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SEMA7A" GraphId="sa117" Type="Protein">
   <DataNode TextLabel="SEMA7A" GraphId="sa117" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="747.5" CenterY="2292.5" Width="80.0" Height="40.0" ZOrder="37" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="747.5" CenterY="2292.5" Width="80.0" Height="40.0" ZOrder="37" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="8482" />
+
     <Xref Database="Entrez Gene" ID="8482"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MET" GraphId="sa118" Type="Protein">
   <DataNode TextLabel="MET" GraphId="sa118" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2152.5" Width="80.0" Height="40.0" ZOrder="38" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2152.5" Width="80.0" Height="40.0" ZOrder="38" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="MET" />
+
     <Xref Database="HGNC" ID="MET"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PLXNC1" GraphId="sa119" Type="Protein">
   <DataNode TextLabel="PLXNC1" GraphId="sa119" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2262.5" Width="80.0" Height="40.0" ZOrder="39" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2262.5" Width="80.0" Height="40.0" ZOrder="39" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9106" />
+
     <Xref Database="HGNC Accession number" ID="9106"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTK2" GraphId="sa12" Type="Protein">
   <DataNode TextLabel="PTK2" GraphId="sa12" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1096.5" CenterY="553.5" Width="80.0" Height="40.0" ZOrder="40" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1096.5" CenterY="553.5" Width="80.0" Height="40.0" ZOrder="40" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9611" />
+
     <Xref Database="HGNC Accession number" ID="9611"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ITGB1" GraphId="sa120" Type="Protein">
   <DataNode TextLabel="ITGB1" GraphId="sa120" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="41" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="41" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002211" />
+
     <Xref Database="RefSeq" ID="NM_002211"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTK2" GraphId="sa121" Type="Protein">
   <DataNode TextLabel="PTK2" GraphId="sa121" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1127.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="42" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1127.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="42" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9611" />
+
     <Xref Database="HGNC Accession number" ID="9611"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAC1" GraphId="sa122" Type="Protein">
   <DataNode TextLabel="RAC1" GraphId="sa122" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2092.5" Width="80.0" Height="40.0" ZOrder="43" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2092.5" Width="80.0" Height="40.0" ZOrder="43" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5879" />
+
     <Xref Database="Entrez Gene" ID="5879"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PAK4" GraphId="sa123" Type="Protein">
   <DataNode TextLabel="PAK4" GraphId="sa123" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="2092.5" Width="80.0" Height="40.0" ZOrder="44" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="2092.5" Width="80.0" Height="40.0" ZOrder="44" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="16059" />
+
     <Xref Database="HGNC Accession number" ID="16059"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RRAS" GraphId="sa125" Type="Protein">
   <DataNode TextLabel="RRAS" GraphId="sa125" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2142.5" Width="80.0" Height="40.0" ZOrder="45" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2142.5" Width="80.0" Height="40.0" ZOrder="45" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="RRAS" />
+
     <Xref Database="HGNC" ID="RRAS"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RND1" GraphId="sa126" Type="Protein">
   <DataNode TextLabel="RND1" GraphId="sa126" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="46" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="46" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="18314" />
+
     <Xref Database="HGNC Accession number" ID="18314"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARHGEF12" GraphId="sa127" Type="Protein">
   <DataNode TextLabel="ARHGEF12" GraphId="sa127" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2242.5" Width="80.0" Height="40.0" ZOrder="47" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2242.5" Width="80.0" Height="40.0" ZOrder="47" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_015313" />
+
     <Xref Database="RefSeq" ID="NM_015313"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOA" GraphId="sa129" Type="Protein">
   <DataNode TextLabel="RHOA" GraphId="sa129" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1317.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="48" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1317.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="48" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="667" />
+
     <Xref Database="HGNC Accession number" ID="667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SRC" GraphId="sa13" Type="Protein" GroupRef="d677a">
   <DataNode TextLabel="SRC" GraphId="sa13" Type="Protein" GroupRef="d677a">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1117.5" CenterY="802.5" Width="80.0" Height="40.0" ZOrder="49" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1117.5" CenterY="802.5" Width="80.0" Height="40.0" ZOrder="49" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="P12931" />
+
     <Xref Database="Uniprot-TrEMBL" ID="P12931"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAF1" GraphId="sa130" Type="Protein">
   <DataNode TextLabel="RAF1" GraphId="sa130" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1467.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="50" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1467.5" CenterY="2192.5" Width="80.0" Height="40.0" ZOrder="50" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000132155" />
+
     <Xref Database="Ensembl" ID="ENSG00000132155"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MAPK1" GraphId="sa132" Type="Protein">
   <DataNode TextLabel="MAPK1" GraphId="sa132" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="51" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="2322.5" Width="80.0" Height="40.0" ZOrder="51" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000100030" />
+
     <Xref Database="Ensembl" ID="ENSG00000100030"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SHH" GraphId="sa134" Type="Protein">
   <DataNode TextLabel="SHH" GraphId="sa134" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="787.5" CenterY="2532.5" Width="80.0" Height="40.0" ZOrder="52" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="787.5" CenterY="2532.5" Width="80.0" Height="40.0" ZOrder="52" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q15465" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q15465"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTCH1" GraphId="sa135" Type="Protein">
   <DataNode TextLabel="PTCH1" GraphId="sa135" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2432.5" Width="80.0" Height="40.0" ZOrder="53" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2432.5" Width="80.0" Height="40.0" ZOrder="53" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_000264" />
+
     <Xref Database="RefSeq" ID="NM_000264"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SMO" GraphId="sa136" Type="Protein">
   <DataNode TextLabel="SMO" GraphId="sa136" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="54" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="54" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="11119" />
+
     <Xref Database="HGNC Accession number" ID="11119"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="BOC" GraphId="sa137" Type="Protein">
   <DataNode TextLabel="BOC" GraphId="sa137" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2602.5" Width="80.0" Height="40.0" ZOrder="55" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2602.5" Width="80.0" Height="40.0" ZOrder="55" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="91653" />
+
     <Xref Database="Entrez Gene" ID="91653"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SMO" GraphId="sa138" Type="Protein">
   <DataNode TextLabel="SMO" GraphId="sa138" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2672.5" Width="80.0" Height="40.0" ZOrder="56" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2672.5" Width="80.0" Height="40.0" ZOrder="56" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="11119" />
+
     <Xref Database="HGNC Accession number" ID="11119"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCA" GraphId="sa139" Type="Protein">
   <DataNode TextLabel="PRKCA" GraphId="sa139" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="57" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="57" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="PRKCA" />
+
     <Xref Database="HGNC" ID="PRKCA"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ILK" GraphId="sa141" Type="Protein">
   <DataNode TextLabel="ILK" GraphId="sa141" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="58" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="2512.5" Width="80.0" Height="40.0" ZOrder="58" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000166333" />
+
     <Xref Database="Ensembl" ID="ENSG00000166333"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="WNT5A" GraphId="sa143" Type="Protein">
   <DataNode TextLabel="WNT5A" GraphId="sa143" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="787.5" CenterY="2792.5" Width="80.0" Height="40.0" ZOrder="59" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="787.5" CenterY="2792.5" Width="80.0" Height="40.0" ZOrder="59" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="WNT5A" />
+
     <Xref Database="HGNC" ID="WNT5A"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FZD3" GraphId="sa144" Type="Protein">
   <DataNode TextLabel="FZD3" GraphId="sa144" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2772.5" Width="80.0" Height="40.0" ZOrder="60" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2772.5" Width="80.0" Height="40.0" ZOrder="60" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FZD3" />
+
     <Xref Database="HGNC" ID="FZD3"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RYK" GraphId="sa145" Type="Protein">
   <DataNode TextLabel="RYK" GraphId="sa145" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2812.5" Width="80.0" Height="40.0" ZOrder="61" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2812.5" Width="80.0" Height="40.0" ZOrder="61" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000163785" />
+
     <Xref Database="Ensembl" ID="ENSG00000163785"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="TRPC1" GraphId="sa147" Type="Protein">
   <DataNode TextLabel="TRPC1" GraphId="sa147" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2862.5" Width="80.0" Height="40.0" ZOrder="62" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2862.5" Width="80.0" Height="40.0" ZOrder="62" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="TRPC1" />
+
     <Xref Database="HGNC" ID="TRPC1"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CAMK2A" GraphId="sa148" Type="Protein">
   <DataNode TextLabel="CAMK2A" GraphId="sa148" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="2862.5" Width="80.0" Height="40.0" ZOrder="63" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="2862.5" Width="80.0" Height="40.0" ZOrder="63" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="1460" />
+
     <Xref Database="HGNC Accession number" ID="1460"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="WNT4" GraphId="sa149" Type="Protein">
   <DataNode TextLabel="WNT4" GraphId="sa149" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="787.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="64" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="787.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="64" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000162552" />
+
     <Xref Database="Ensembl" ID="ENSG00000162552"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="UNC5D" GraphId="sa15" Type="Protein">
   <DataNode TextLabel="UNC5D" GraphId="sa15" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="802.5" Width="80.0" Height="40.0" ZOrder="65" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="802.5" Width="80.0" Height="40.0" ZOrder="65" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q6UXZ4" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q6UXZ4"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FZD3" GraphId="sa150" Type="Protein">
   <DataNode TextLabel="FZD3" GraphId="sa150" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="66" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="66" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FZD3" />
+
     <Xref Database="HGNC" ID="FZD3"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PIK3CA" GraphId="sa151" Type="Protein">
   <DataNode TextLabel="PIK3CA" GraphId="sa151" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="67" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="67" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="8975" />
+
     <Xref Database="HGNC Accession number" ID="8975"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PDPK1" GraphId="sa152" Type="Protein">
   <DataNode TextLabel="PDPK1" GraphId="sa152" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="68" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="68" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000140992" />
+
     <Xref Database="Ensembl" ID="ENSG00000140992"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PRKCZ" GraphId="sa153" Type="Protein">
   <DataNode TextLabel="PRKCZ" GraphId="sa153" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1457.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="69" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1457.5" CenterY="2972.5" Width="80.0" Height="40.0" ZOrder="69" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5590" />
+
     <Xref Database="Entrez Gene" ID="5590"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PARD3" GraphId="sa154" Type="Protein">
   <DataNode TextLabel="PARD3" GraphId="sa154" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1457.5" CenterY="2932.5" Width="80.0" Height="40.0" ZOrder="70" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1457.5" CenterY="2932.5" Width="80.0" Height="40.0" ZOrder="70" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="PARD3" />
+
     <Xref Database="HGNC" ID="PARD3"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PARD6A" GraphId="sa155" Type="Protein">
   <DataNode TextLabel="PARD6A" GraphId="sa155" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1457.5" CenterY="3012.5" Width="80.0" Height="40.0" ZOrder="71" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1457.5" CenterY="3012.5" Width="80.0" Height="40.0" ZOrder="71" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000102981" />
+
     <Xref Database="Ensembl" ID="ENSG00000102981"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="TRPC1" GraphId="sa157" Type="Protein">
   <DataNode TextLabel="TRPC1" GraphId="sa157" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="72" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="72" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="TRPC1" />
+
     <Xref Database="HGNC" ID="TRPC1"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PPP3CA" GraphId="sa159" Type="Protein">
   <DataNode TextLabel="PPP3CA" GraphId="sa159" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="73" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="73" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9314" />
+
     <Xref Database="HGNC Accession number" ID="9314"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NTN1" GraphId="sa16" Type="Protein">
   <DataNode TextLabel="NTN1" GraphId="sa16" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="807.5" CenterY="662.5" Width="80.0" Height="40.0" ZOrder="74" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="807.5" CenterY="662.5" Width="80.0" Height="40.0" ZOrder="74" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="8029" />
+
     <Xref Database="HGNC Accession number" ID="8029"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="BMPR2" GraphId="sa160" Type="Protein">
   <DataNode TextLabel="BMPR2" GraphId="sa160" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="3192.5" Width="80.0" Height="40.0" ZOrder="75" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="3192.5" Width="80.0" Height="40.0" ZOrder="75" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="659" />
+
     <Xref Database="Entrez Gene" ID="659"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="BMPR1B" GraphId="sa161" Type="Protein">
   <DataNode TextLabel="BMPR1B" GraphId="sa161" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="3232.5" Width="80.0" Height="40.0" ZOrder="76" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="3232.5" Width="80.0" Height="40.0" ZOrder="76" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="658" />
+
     <Xref Database="Entrez Gene" ID="658"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="BMP7" GraphId="sa162" Type="Protein">
   <DataNode TextLabel="BMP7" GraphId="sa162" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="787.5" CenterY="3192.5" Width="80.0" Height="40.0" ZOrder="77" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="787.5" CenterY="3192.5" Width="80.0" Height="40.0" ZOrder="77" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="1074" />
+
     <Xref Database="HGNC Accession number" ID="1074"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GDF7" GraphId="sa163" Type="Protein">
   <DataNode TextLabel="GDF7" GraphId="sa163" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="787.5" CenterY="3232.5" Width="80.0" Height="40.0" ZOrder="78" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="787.5" CenterY="3232.5" Width="80.0" Height="40.0" ZOrder="78" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="GDF7" />
+
     <Xref Database="HGNC" ID="GDF7"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SHH" GraphId="sa165" Type="Protein">
   <DataNode TextLabel="SHH" GraphId="sa165" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1457.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="79" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1457.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="79" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q15465" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q15465"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CFL1" GraphId="sa166" Type="Protein">
   <DataNode TextLabel="CFL1" GraphId="sa166" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1647.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="80" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1647.5" CenterY="3092.5" Width="80.0" Height="40.0" ZOrder="80" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000172757" />
+
     <Xref Database="Ensembl" ID="ENSG00000172757"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LIMK1" GraphId="sa168" Type="Protein">
   <DataNode TextLabel="LIMK1" GraphId="sa168" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1117.5" CenterY="3212.5" Width="80.0" Height="40.0" ZOrder="81" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1117.5" CenterY="3212.5" Width="80.0" Height="40.0" ZOrder="81" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="6613" />
+
     <Xref Database="HGNC Accession number" ID="6613"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CFL1" GraphId="sa169" Type="Protein">
   <DataNode TextLabel="CFL1" GraphId="sa169" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1287.5" CenterY="3212.5" Width="80.0" Height="40.0" ZOrder="82" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1287.5" CenterY="3212.5" Width="80.0" Height="40.0" ZOrder="82" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000172757" />
+
     <Xref Database="Ensembl" ID="ENSG00000172757"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NTN3" GraphId="sa17" Type="Protein">
   <DataNode TextLabel="NTN3" GraphId="sa17" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="807.5" CenterY="712.5" Width="80.0" Height="40.0" ZOrder="83" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="807.5" CenterY="712.5" Width="80.0" Height="40.0" ZOrder="83" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="4917" />
+
     <Xref Database="Entrez Gene" ID="4917"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CDC42" GraphId="sa170" Type="Protein">
   <DataNode TextLabel="CDC42" GraphId="sa170" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1420.0" CenterY="610.0" Width="80.0" Height="40.0" ZOrder="84" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1420.0" CenterY="610.0" Width="80.0" Height="40.0" ZOrder="84" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="998" />
+
     <Xref Database="Entrez Gene" ID="998"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NCK2" GraphId="sa171" Type="Protein">
   <DataNode TextLabel="NCK2" GraphId="sa171" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1110.0" CenterY="1660.0" Width="80.0" Height="40.0" ZOrder="85" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1110.0" CenterY="1660.0" Width="80.0" Height="40.0" ZOrder="85" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="7665" />
+
     <Xref Database="HGNC Accession number" ID="7665"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CDC42" GraphId="sa172" Type="Protein">
   <DataNode TextLabel="CDC42" GraphId="sa172" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1410.0" CenterY="1530.0" Width="80.0" Height="40.0" ZOrder="86" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1410.0" CenterY="1530.0" Width="80.0" Height="40.0" ZOrder="86" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="998" />
+
     <Xref Database="Entrez Gene" ID="998"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GSK3B" GraphId="sa173" Type="Protein">
   <DataNode TextLabel="GSK3B" GraphId="sa173" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1430.0" CenterY="2000.0" Width="80.0" Height="40.0" ZOrder="87" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1430.0" CenterY="2000.0" Width="80.0" Height="40.0" ZOrder="87" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="GSK3B" />
+
     <Xref Database="HGNC" ID="GSK3B"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FYN" GraphId="sa174" Type="Protein">
   <DataNode TextLabel="FYN" GraphId="sa174" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1110.0" CenterY="2680.0" Width="80.0" Height="40.0" ZOrder="88" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1110.0" CenterY="2680.0" Width="80.0" Height="40.0" ZOrder="88" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FYN" />
+
     <Xref Database="HGNC" ID="FYN"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GSK3B" GraphId="sa175" Type="Protein">
   <DataNode TextLabel="GSK3B" GraphId="sa175" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1640.0" CenterY="2970.0" Width="80.0" Height="40.0" ZOrder="89" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1640.0" CenterY="2970.0" Width="80.0" Height="40.0" ZOrder="89" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="GSK3B" />
+
     <Xref Database="HGNC" ID="GSK3B"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NTN4" GraphId="sa18" Type="Protein">
   <DataNode TextLabel="NTN4" GraphId="sa18" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="807.5" CenterY="762.5" Width="80.0" Height="40.0" ZOrder="90" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="807.5" CenterY="762.5" Width="80.0" Height="40.0" ZOrder="90" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="59277" />
+
     <Xref Database="Entrez Gene" ID="59277"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="DCC" GraphId="sa19" Type="Protein">
   <DataNode TextLabel="DCC" GraphId="sa19" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="762.5" Width="80.0" Height="40.0" ZOrder="91" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="762.5" Width="80.0" Height="40.0" ZOrder="91" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_005215" />
+
     <Xref Database="RefSeq" ID="NM_005215"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LRRC4" GraphId="sa2" Type="Protein">
   <DataNode TextLabel="LRRC4" GraphId="sa2" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="960.0" CenterY="220.0" Width="80.0" Height="40.0" ZOrder="92" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="960.0" CenterY="220.0" Width="80.0" Height="40.0" ZOrder="92" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="15586" />
+
     <Xref Database="HGNC Accession number" ID="15586"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTK2" GraphId="sa22" Type="Protein" GroupRef="d677a">
   <DataNode TextLabel="PTK2" GraphId="sa22" Type="Protein" GroupRef="d677a">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1117.5" CenterY="722.5" Width="80.0" Height="40.0" ZOrder="93" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1117.5" CenterY="722.5" Width="80.0" Height="40.0" ZOrder="93" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9611" />
+
     <Xref Database="HGNC Accession number" ID="9611"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NCK1" GraphId="sa23" Type="Protein">
   <DataNode TextLabel="NCK1" GraphId="sa23" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1097.5" CenterY="612.5" Width="80.0" Height="40.0" ZOrder="94" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1097.5" CenterY="612.5" Width="80.0" Height="40.0" ZOrder="94" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000158092" />
+
     <Xref Database="Ensembl" ID="ENSG00000158092"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTPN11" GraphId="sa24" Type="Protein">
   <DataNode TextLabel="PTPN11" GraphId="sa24" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1017.5" CenterY="842.5" Width="80.0" Height="40.0" ZOrder="95" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1017.5" CenterY="842.5" Width="80.0" Height="40.0" ZOrder="95" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9644" />
+
     <Xref Database="HGNC Accession number" ID="9644"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NFATC2" GraphId="sa25" Type="Protein">
   <DataNode TextLabel="NFATC2" GraphId="sa25" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1357.5" CenterY="402.5" Width="80.0" Height="40.0" ZOrder="96" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1357.5" CenterY="402.5" Width="80.0" Height="40.0" ZOrder="96" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="7776" />
+
     <Xref Database="HGNC Accession number" ID="7776"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PAK4" GraphId="sa26" Type="Protein">
   <DataNode TextLabel="PAK4" GraphId="sa26" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1177.5" CenterY="612.5" Width="80.0" Height="40.0" ZOrder="97" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1177.5" CenterY="612.5" Width="80.0" Height="40.0" ZOrder="97" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="16059" />
+
     <Xref Database="HGNC Accession number" ID="16059"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SRC" GraphId="sa27" Type="Protein">
   <DataNode TextLabel="SRC" GraphId="sa27" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1237.5" CenterY="572.5" Width="80.0" Height="40.0" ZOrder="98" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1237.5" CenterY="572.5" Width="80.0" Height="40.0" ZOrder="98" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="P12931" />
+
     <Xref Database="Uniprot-TrEMBL" ID="P12931"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FYN" GraphId="sa28" Type="Protein">
   <DataNode TextLabel="FYN" GraphId="sa28" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1237.5" CenterY="532.5" Width="80.0" Height="40.0" ZOrder="99" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1237.5" CenterY="532.5" Width="80.0" Height="40.0" ZOrder="99" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FYN" />
+
     <Xref Database="HGNC" ID="FYN"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOA" GraphId="sa29" Type="Protein">
   <DataNode TextLabel="RHOA" GraphId="sa29" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1237.5" CenterY="462.5" Width="80.0" Height="40.0" ZOrder="100" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1237.5" CenterY="462.5" Width="80.0" Height="40.0" ZOrder="100" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="667" />
+
     <Xref Database="HGNC Accession number" ID="667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="TRPC1" GraphId="sa3" Type="Protein">
   <DataNode TextLabel="TRPC1" GraphId="sa3" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="967.5" CenterY="352.5" Width="80.0" Height="40.0" ZOrder="101" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="967.5" CenterY="352.5" Width="80.0" Height="40.0" ZOrder="101" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="TRPC1" />
+
     <Xref Database="HGNC" ID="TRPC1"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROCK1" GraphId="sa30" Type="Protein">
   <DataNode TextLabel="ROCK1" GraphId="sa30" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1357.5" CenterY="462.5" Width="80.0" Height="40.0" ZOrder="102" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1357.5" CenterY="462.5" Width="80.0" Height="40.0" ZOrder="102" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6093" />
+
     <Xref Database="Entrez Gene" ID="6093"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAC1" GraphId="sa33" Type="Protein">
   <DataNode TextLabel="RAC1" GraphId="sa33" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1420.0" CenterY="570.0" Width="80.0" Height="40.0" ZOrder="103" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1420.0" CenterY="570.0" Width="80.0" Height="40.0" ZOrder="103" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5879" />
+
     <Xref Database="Entrez Gene" ID="5879"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ABLIM3" GraphId="sa35" Type="Protein">
   <DataNode TextLabel="ABLIM3" GraphId="sa35" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1556.5" CenterY="590.5" Width="80.0" Height="40.0" ZOrder="104" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1556.5" CenterY="590.5" Width="80.0" Height="40.0" ZOrder="104" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="O94929" />
+
     <Xref Database="Uniprot-TrEMBL" ID="O94929"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NEO1" GraphId="sa38" Type="Protein">
   <DataNode TextLabel="NEO1" GraphId="sa38" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="105" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="105" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="7754" />
+
     <Xref Database="HGNC Accession number" ID="7754"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LRIG2" GraphId="sa39" Type="Protein">
   <DataNode TextLabel="LRIG2" GraphId="sa39" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1022.5" Width="80.0" Height="40.0" ZOrder="106" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1022.5" Width="80.0" Height="40.0" ZOrder="106" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="9860" />
+
     <Xref Database="Entrez Gene" ID="9860"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NTNG1" GraphId="sa4" Type="Protein">
   <DataNode TextLabel="NTNG1" GraphId="sa4" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="880.0" CenterY="180.0" Width="80.0" Height="40.0" ZOrder="107" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="880.0" CenterY="180.0" Width="80.0" Height="40.0" ZOrder="107" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="23319" />
+
     <Xref Database="HGNC Accession number" ID="23319"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGMA" GraphId="sa40" Type="Protein">
   <DataNode TextLabel="RGMA" GraphId="sa40" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="777.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="108" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="777.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="108" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="56963" />
+
     <Xref Database="Entrez Gene" ID="56963"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTK2" GraphId="sa41" Type="Protein">
   <DataNode TextLabel="PTK2" GraphId="sa41" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1157.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="109" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1157.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="109" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9611" />
+
     <Xref Database="HGNC Accession number" ID="9611"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ARHGEF12" GraphId="sa42" Type="Protein">
   <DataNode TextLabel="ARHGEF12" GraphId="sa42" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1027.5" CenterY="972.5" Width="80.0" Height="40.0" ZOrder="110" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1027.5" CenterY="972.5" Width="80.0" Height="40.0" ZOrder="110" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_015313" />
+
     <Xref Database="RefSeq" ID="NM_015313"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOA" GraphId="sa43" Type="Protein">
   <DataNode TextLabel="RHOA" GraphId="sa43" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1297.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="111" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1297.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="111" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="667" />
+
     <Xref Database="HGNC Accession number" ID="667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROCK1" GraphId="sa44" Type="Protein">
   <DataNode TextLabel="ROCK1" GraphId="sa44" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1417.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="112" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1417.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="112" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6093" />
+
     <Xref Database="Entrez Gene" ID="6093"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MYL12B" GraphId="sa45" Type="Protein">
   <DataNode TextLabel="MYL12B" GraphId="sa45" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1547.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="113" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1547.5" CenterY="932.5" Width="80.0" Height="40.0" ZOrder="113" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="103910" />
+
     <Xref Database="Entrez Gene" ID="103910"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="EPHA2" GraphId="sa46" Type="Protein">
   <DataNode TextLabel="EPHA2" GraphId="sa46" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1152.5" Width="80.0" Height="40.0" ZOrder="114" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1152.5" Width="80.0" Height="40.0" ZOrder="114" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="EPHA2" />
+
     <Xref Database="HGNC" ID="EPHA2"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="EPHB1" GraphId="sa47" Type="Protein">
   <DataNode TextLabel="EPHB1" GraphId="sa47" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1202.5" Width="80.0" Height="40.0" ZOrder="115" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1202.5" Width="80.0" Height="40.0" ZOrder="115" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="EPHB1" />
+
     <Xref Database="HGNC" ID="EPHB1"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ABL1" GraphId="sa48" Type="Protein">
   <DataNode TextLabel="ABL1" GraphId="sa48" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1117.5" CenterY="1102.5" Width="80.0" Height="40.0" ZOrder="116" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1117.5" CenterY="1102.5" Width="80.0" Height="40.0" ZOrder="116" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000097007" />
+
     <Xref Database="Ensembl" ID="ENSG00000097007"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NTNG2" GraphId="sa5" Type="Protein">
   <DataNode TextLabel="NTNG2" GraphId="sa5" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="880.0" CenterY="220.0" Width="80.0" Height="40.0" ZOrder="117" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="880.0" CenterY="220.0" Width="80.0" Height="40.0" ZOrder="117" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_032536" />
+
     <Xref Database="RefSeq" ID="NM_032536"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RASA1" GraphId="sa50" Type="Protein">
   <DataNode TextLabel="RASA1" GraphId="sa50" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1120.0" CenterY="1172.0" Width="80.0" Height="40.0" ZOrder="118" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1120.0" CenterY="1172.0" Width="80.0" Height="40.0" ZOrder="118" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002890" />
+
     <Xref Database="RefSeq" ID="NM_002890"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NGEF" GraphId="sa51" Type="Protein">
   <DataNode TextLabel="NGEF" GraphId="sa51" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1117.5" CenterY="1252.5" Width="80.0" Height="40.0" ZOrder="119" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1117.5" CenterY="1252.5" Width="80.0" Height="40.0" ZOrder="119" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q8N5V2" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q8N5V2"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ENAH" GraphId="sa52" Type="Protein">
   <DataNode TextLabel="ENAH" GraphId="sa52" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1257.5" CenterY="1102.5" Width="80.0" Height="40.0" ZOrder="120" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1257.5" CenterY="1102.5" Width="80.0" Height="40.0" ZOrder="120" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_018212" />
+
     <Xref Database="RefSeq" ID="NM_018212"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="HRAS" GraphId="sa53" Type="Protein">
   <DataNode TextLabel="HRAS" GraphId="sa53" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1256.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="121" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1256.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="121" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000174775" />
+
     <Xref Database="Ensembl" ID="ENSG00000174775"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MAPK1" GraphId="sa54" Type="Protein">
   <DataNode TextLabel="MAPK1" GraphId="sa54" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1407.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="122" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1407.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="122" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000100030" />
+
     <Xref Database="Ensembl" ID="ENSG00000100030"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAC1" GraphId="sa56" Type="Protein">
   <DataNode TextLabel="RAC1" GraphId="sa56" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1257.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="123" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1257.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="123" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5879" />
+
     <Xref Database="Entrez Gene" ID="5879"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CDC42" GraphId="sa57" Type="Protein">
   <DataNode TextLabel="CDC42" GraphId="sa57" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1257.5" CenterY="1272.5" Width="80.0" Height="40.0" ZOrder="124" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1257.5" CenterY="1272.5" Width="80.0" Height="40.0" ZOrder="124" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="998" />
+
     <Xref Database="Entrez Gene" ID="998"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOA" GraphId="sa58" Type="Protein">
   <DataNode TextLabel="RHOA" GraphId="sa58" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1257.5" CenterY="1332.5" Width="80.0" Height="40.0" ZOrder="125" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1257.5" CenterY="1332.5" Width="80.0" Height="40.0" ZOrder="125" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="667" />
+
     <Xref Database="HGNC Accession number" ID="667"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROCK1" GraphId="sa59" Type="Protein">
   <DataNode TextLabel="ROCK1" GraphId="sa59" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1407.5" CenterY="1332.5" Width="80.0" Height="40.0" ZOrder="126" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1407.5" CenterY="1332.5" Width="80.0" Height="40.0" ZOrder="126" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="6093" />
+
     <Xref Database="Entrez Gene" ID="6093"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="EFNA1" GraphId="sa61" Type="Protein">
   <DataNode TextLabel="EFNA1" GraphId="sa61" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="597.5" CenterY="1152.5" Width="80.0" Height="40.0" ZOrder="127" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="597.5" CenterY="1152.5" Width="80.0" Height="40.0" ZOrder="127" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="1942" />
+
     <Xref Database="Entrez Gene" ID="1942"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="EFNB1" GraphId="sa62" Type="Protein">
   <DataNode TextLabel="EFNB1" GraphId="sa62" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="597.5" CenterY="1202.5" Width="80.0" Height="40.0" ZOrder="128" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="597.5" CenterY="1202.5" Width="80.0" Height="40.0" ZOrder="128" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="P98172" />
+
     <Xref Database="Uniprot-TrEMBL" ID="P98172"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CXCR4" GraphId="sa63" Type="Protein">
   <DataNode TextLabel="CXCR4" GraphId="sa63" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="597.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="129" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="597.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="129" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_001008540" />
+
     <Xref Database="RefSeq" ID="NM_001008540"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CXCR4" GraphId="sa65" Type="Protein">
   <DataNode TextLabel="CXCR4" GraphId="sa65" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="130" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="130" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_001008540" />
+
     <Xref Database="RefSeq" ID="NM_001008540"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="CXCL12" GraphId="sa66" Type="Protein">
   <DataNode TextLabel="CXCL12" GraphId="sa66" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="777.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="131" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="777.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="131" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="P48061" />
+
     <Xref Database="Uniprot-TrEMBL" ID="P48061"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PAK4" GraphId="sa69" Type="Protein">
   <DataNode TextLabel="PAK4" GraphId="sa69" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1407.5" CenterY="1252.5" Width="80.0" Height="40.0" ZOrder="132" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1407.5" CenterY="1252.5" Width="80.0" Height="40.0" ZOrder="132" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="16059" />
+
     <Xref Database="HGNC Accession number" ID="16059"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RASA1" GraphId="sa71" Type="Protein">
   <DataNode TextLabel="RASA1" GraphId="sa71" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="457.5" CenterY="1132.5" Width="80.0" Height="40.0" ZOrder="133" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="457.5" CenterY="1132.5" Width="80.0" Height="40.0" ZOrder="133" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002890" />
+
     <Xref Database="RefSeq" ID="NM_002890"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="FYN" GraphId="sa72" Type="Protein">
   <DataNode TextLabel="FYN" GraphId="sa72" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="457.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="134" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="457.5" CenterY="1172.5" Width="80.0" Height="40.0" ZOrder="134" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="FYN" />
+
     <Xref Database="HGNC" ID="FYN"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NCK2" GraphId="sa74" Type="Protein">
   <DataNode TextLabel="NCK2" GraphId="sa74" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="457.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="135" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="457.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="135" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="7665" />
+
     <Xref Database="HGNC Accession number" ID="7665"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PTK2" GraphId="sa75" Type="Protein">
   <DataNode TextLabel="PTK2" GraphId="sa75" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="327.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="136" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="327.5" CenterY="1232.5" Width="80.0" Height="40.0" ZOrder="136" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9611" />
+
     <Xref Database="HGNC Accession number" ID="9611"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RGS3" GraphId="sa77" Type="Protein">
   <DataNode TextLabel="RGS3" GraphId="sa77" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="457.5" CenterY="1292.5" Width="80.0" Height="40.0" ZOrder="137" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="457.5" CenterY="1292.5" Width="80.0" Height="40.0" ZOrder="137" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9999" />
+
     <Xref Database="HGNC Accession number" ID="9999"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNAI1" GraphId="sa78" Type="Protein">
   <DataNode TextLabel="GNAI1" GraphId="sa78" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="457.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="138" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="457.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="138" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002069" />
+
     <Xref Database="RefSeq" ID="NM_002069"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PPP3CA" GraphId="sa8" Type="Protein">
   <DataNode TextLabel="PPP3CA" GraphId="sa8" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1227.5" CenterY="352.5" Width="80.0" Height="40.0" ZOrder="139" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1227.5" CenterY="352.5" Width="80.0" Height="40.0" ZOrder="139" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="9314" />
+
     <Xref Database="HGNC Accession number" ID="9314"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="GNAI1" GraphId="sa80" Type="Protein">
   <DataNode TextLabel="GNAI1" GraphId="sa80" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="140" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1412.5" Width="80.0" Height="40.0" ZOrder="140" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_002069" />
+
     <Xref Database="RefSeq" ID="NM_002069"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROBO2" GraphId="sa83" Type="Protein">
   <DataNode TextLabel="ROBO2" GraphId="sa83" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1552.5" Width="80.0" Height="40.0" ZOrder="141" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1552.5" Width="80.0" Height="40.0" ZOrder="141" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_001128929" />
+
     <Xref Database="RefSeq" ID="NM_001128929"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROBO1" GraphId="sa84" Type="Protein">
   <DataNode TextLabel="ROBO1" GraphId="sa84" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1592.5" Width="80.0" Height="40.0" ZOrder="142" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1592.5" Width="80.0" Height="40.0" ZOrder="142" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="Q9Y6N7" />
+
     <Xref Database="Uniprot-TrEMBL" ID="Q9Y6N7"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLIT1" GraphId="sa85" Type="Protein">
   <DataNode TextLabel="SLIT1" GraphId="sa85" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="777.5" CenterY="1552.5" Width="80.0" Height="40.0" ZOrder="143" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="777.5" CenterY="1552.5" Width="80.0" Height="40.0" ZOrder="143" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="SLIT1" />
+
     <Xref Database="HGNC" ID="SLIT1"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLIT2" GraphId="sa86" Type="Protein">
   <DataNode TextLabel="SLIT2" GraphId="sa86" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="777.5" CenterY="1592.5" Width="80.0" Height="40.0" ZOrder="144" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="777.5" CenterY="1592.5" Width="80.0" Height="40.0" ZOrder="144" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="9353" />
+
     <Xref Database="Entrez Gene" ID="9353"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SLIT3" GraphId="sa87" Type="Protein">
   <DataNode TextLabel="SLIT3" GraphId="sa87" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="777.5" CenterY="1652.5" Width="80.0" Height="40.0" ZOrder="145" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="777.5" CenterY="1652.5" Width="80.0" Height="40.0" ZOrder="145" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC" ID="SLIT3" />
+
     <Xref Database="HGNC" ID="SLIT3"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ROBO3" GraphId="sa88" Type="Protein">
   <DataNode TextLabel="ROBO3" GraphId="sa88" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="957.5" CenterY="1672.5" Width="80.0" Height="40.0" ZOrder="146" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="957.5" CenterY="1672.5" Width="80.0" Height="40.0" ZOrder="146" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_022370" />
+
     <Xref Database="RefSeq" ID="NM_022370"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ABL1" GraphId="sa89" Type="Protein">
   <DataNode TextLabel="ABL1" GraphId="sa89" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1522.5" Width="80.0" Height="40.0" ZOrder="147" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1522.5" Width="80.0" Height="40.0" ZOrder="147" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Ensembl" ID="ENSG00000097007" />
+
     <Xref Database="Ensembl" ID="ENSG00000097007"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="NFATC2" GraphId="sa9" Type="Protein">
   <DataNode TextLabel="NFATC2" GraphId="sa9" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1357.5" CenterY="302.5" Width="80.0" Height="40.0" ZOrder="148" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1357.5" CenterY="302.5" Width="80.0" Height="40.0" ZOrder="148" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="7776" />
+
     <Xref Database="HGNC Accession number" ID="7776"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="ENAH" GraphId="sa90" Type="Protein">
   <DataNode TextLabel="ENAH" GraphId="sa90" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="1522.5" Width="80.0" Height="40.0" ZOrder="149" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="1522.5" Width="80.0" Height="40.0" ZOrder="149" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_018212" />
+
     <Xref Database="RefSeq" ID="NM_018212"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="SRGAP2" GraphId="sa91" Type="Protein">
   <DataNode TextLabel="SRGAP2" GraphId="sa91" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1110.0" CenterY="1570.0" Width="80.0" Height="40.0" ZOrder="150" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1110.0" CenterY="1570.0" Width="80.0" Height="40.0" ZOrder="150" FontSize="12" Valign="Middle"/>
-
     <Xref Database="RefSeq" ID="NM_015326" />
+
     <Xref Database="RefSeq" ID="NM_015326"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PAK4" GraphId="sa92" Type="Protein">
   <DataNode TextLabel="PAK4" GraphId="sa92" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1110.0" CenterY="1620.0" Width="80.0" Height="40.0" ZOrder="151" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1110.0" CenterY="1620.0" Width="80.0" Height="40.0" ZOrder="151" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="16059" />
+
     <Xref Database="HGNC Accession number" ID="16059"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAC1" GraphId="sa94" Type="Protein">
   <DataNode TextLabel="RAC1" GraphId="sa94" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="1642.5" Width="80.0" Height="40.0" ZOrder="152" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="1642.5" Width="80.0" Height="40.0" ZOrder="152" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5879" />
+
     <Xref Database="Entrez Gene" ID="5879"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RAC1" GraphId="sa95" Type="Protein">
   <DataNode TextLabel="RAC1" GraphId="sa95" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="153" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="153" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Entrez Gene" ID="5879" />
+
     <Xref Database="Entrez Gene" ID="5879"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="PAK4" GraphId="sa96" Type="Protein">
   <DataNode TextLabel="PAK4" GraphId="sa96" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="154" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="154" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="16059" />
+
     <Xref Database="HGNC Accession number" ID="16059"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RHOD" GraphId="sa97" Type="Protein">
   <DataNode TextLabel="RHOD" GraphId="sa97" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="155" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1107.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="155" FontSize="12" Valign="Middle"/>
-
     <Xref Database="Uniprot-TrEMBL" ID="O00212" />
+
     <Xref Database="Uniprot-TrEMBL" ID="O00212"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="RND1" GraphId="sa98" Type="Protein">
   <DataNode TextLabel="RND1" GraphId="sa98" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1267.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="156" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1267.5" CenterY="1832.5" Width="80.0" Height="40.0" ZOrder="156" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="18314" />
+
     <Xref Database="HGNC Accession number" ID="18314"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="LIMK1" GraphId="sa99" Type="Protein">
   <DataNode TextLabel="LIMK1" GraphId="sa99" Type="Protein">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1427.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="157" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1427.5" CenterY="1782.5" Width="80.0" Height="40.0" ZOrder="157" FontSize="12" Valign="Middle"/>
-
     <Xref Database="HGNC Accession number" ID="6613" />
+
     <Xref Database="HGNC Accession number" ID="6613"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Ca2+" GraphId="sa140" Type="Metabolite">
   <DataNode TextLabel="Ca2+" GraphId="sa140" Type="Metabolite">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2432.5" Width="52.5" Height="42.5" ZOrder="161" FontSize="12" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1107.5" CenterY="2432.5" Width="52.5" Height="42.5" ZOrder="161" FontSize="12" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:29108" />
+
     <Xref Database="ChEBI" ID="CHEBI:29108"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Ca2+" GraphId="sa146" Type="Metabolite">
   <DataNode TextLabel="Ca2+" GraphId="sa146" Type="Metabolite">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1107.5" CenterY="2862.5" Width="52.5" Height="42.5" ZOrder="162" FontSize="12" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1107.5" CenterY="2862.5" Width="52.5" Height="42.5" ZOrder="162" FontSize="12" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:29108" />
+
     <Xref Database="ChEBI" ID="CHEBI:29108"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Ca2+" GraphId="sa158" Type="Metabolite">
   <DataNode TextLabel="Ca2+" GraphId="sa158" Type="Metabolite">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1098.1666666666677" CenterY="3091.1666666666656" Width="52.5" Height="42.5" ZOrder="163" FontSize="12" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1098.1666666666677" CenterY="3091.1666666666656" Width="52.5" Height="42.5" ZOrder="163" FontSize="12" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:29108" />
+
     <Xref Database="ChEBI" ID="CHEBI:29108"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Ca2+" GraphId="sa7" Type="Metabolite">
   <DataNode TextLabel="Ca2+" GraphId="sa7" Type="Metabolite">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1097.5" CenterY="352.4999999999999" Width="52.5" Height="42.5" ZOrder="164" FontSize="12" Valign="Middle" Color="0000ff" />
+
     <Graphics CenterX="1097.5" CenterY="352.4999999999999" Width="52.5" Height="42.5" ZOrder="164" FontSize="12" Valign="Middle" Color="0000ff"/>
-
     <Xref Database="ChEBI" ID="CHEBI:29108" />
+
     <Xref Database="ChEBI" ID="CHEBI:29108"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="" GraphId="sa60">
   <DataNode TextLabel="" GraphId="sa60">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="997.5" CenterY="1172.5" Width="25.0" Height="22.5" ZOrder="166" FontSize="12" Valign="Middle" ShapeType="Oval" />
+
     <Graphics CenterX="997.5" CenterY="1172.5" Width="25.0" Height="22.5" ZOrder="166" FontSize="12" Valign="Middle" ShapeType="Oval"/>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="b0cf2" Type="Pathway">
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="b0cf2" Type="Pathway">
-
     <Graphics CenterX="1645.5000000000005" CenterY="462.6666666666668" Width="212.99999999999994" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1645.5000000000005" CenterY="462.6666666666668" Width="212.99999999999994" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04810" />
+
     <Xref Database="KEGG Pathway" ID="hsa04810"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Cytokine-cytokine receptor interaction" GraphId="b430b" Type="Pathway">
   <DataNode TextLabel="Cytokine-cytokine receptor interaction" GraphId="b430b" Type="Pathway">
-
     <Graphics CenterX="790.8333333333331" CenterY="1298.666666666666" Width="239.66666666666654" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="790.8333333333331" CenterY="1298.666666666666" Width="239.66666666666654" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04060" />
+
     <Xref Database="KEGG Pathway" ID="hsa04060"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Wnt signaling pathway" GraphId="df150" Type="Pathway">
   <DataNode TextLabel="Wnt signaling pathway" GraphId="df150" Type="Pathway">
-
     <Graphics CenterX="653.8333333333335" CenterY="2893.3333333333335" Width="166.33333333333294" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="653.8333333333335" CenterY="2893.3333333333335" Width="166.33333333333294" Height="25.0" ZOrder="32768" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04310" />
+
     <Xref Database="KEGG Pathway" ID="hsa04310"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="f96a7" Type="Pathway">
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="f96a7" Type="Pathway">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1923.5000000000011" CenterY="3215.1666666666665" Width="220.0" Height="30.0" ZOrder="32774" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1923.5000000000011" CenterY="3215.1666666666665" Width="220.0" Height="30.0" ZOrder="32774" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04810" />
+
     <Xref Database="KEGG Pathway" ID="hsa04810"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="b3d54" Type="Pathway">
   <DataNode TextLabel="Regulation of actin cytoskeleton" GraphId="b3d54" Type="Pathway">
-
     <Graphics CenterX="1888.3750000000002" CenterY="1530.7500000000007" Width="215.91666666666686" Height="25.0" ZOrder="32775" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1888.3750000000002" CenterY="1530.7500000000007" Width="215.91666666666686" Height="25.0" ZOrder="32775" FontWeight="Bold" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04810" />
+
     <Xref Database="KEGG Pathway" ID="hsa04810"/>
   </DataNode>
   </DataNode>
   <DataNode TextLabel="MAPK signaling pathway" GraphId="ae2d7" Type="Pathway">
   <DataNode TextLabel="MAPK signaling pathway" GraphId="ae2d7" Type="Pathway">
-
     <Comment></Comment>
+
     <Comment/>
-
     <Graphics CenterX="1941.5" CenterY="1214.5" Width="180.0" Height="30.0" ZOrder="32776" FontSize="12" Valign="Middle" Color="14961e" />
+
     <Graphics CenterX="1941.5" CenterY="1214.5" Width="180.0" Height="30.0" ZOrder="32776" FontSize="12" Valign="Middle" Color="14961e"/>
-
     <Xref Database="KEGG Pathway" ID="hsa04010" />
+
     <Xref Database="KEGG Pathway" ID="hsa04010"/>
   </DataNode>
   </DataNode>
   <State GraphRef="sa25" TextLabel="P" GraphId="sa25-rs1">
   <State GraphRef="sa25" TextLabel="P" GraphId="sa25-rs1">
-
     <Graphics RelX="-0.9142439901038983" RelY="-0.921512019792209" Width="15.0" Height="15.0" ShapeType="Oval" />
+
     <Graphics RelX="-0.9142439901038983" RelY="-0.921512019792209" Width="15.0" Height="15.0" ShapeType="Oval"/>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </State>
   </State>
   <State GraphRef="sa9" TextLabel="" GraphId="sa9-rs1">
   <State GraphRef="sa9" TextLabel="" GraphId="sa9-rs1">
-
     <Graphics RelX="-0.9142439901038927" RelY="-0.9215120197922175" Width="15.0" Height="15.0" ShapeType="Oval" />
+
     <Graphics RelX="-0.9142439901038927" RelY="-0.9215120197922175" Width="15.0" Height="15.0" ShapeType="Oval"/>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </State>
   </State>
   <Interaction GraphId="re1">
   <Interaction GraphId="re1">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="167" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="167" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1000.0" Y="190.0" GraphRef="sa1" RelX="1.0" RelY="0.5" />
+
       <Point X="1000.0" Y="190.0" GraphRef="sa1" RelX="1.0" RelY="0.5"/>
-
       <Point X="2360.166666666664" Y="290.16666666666674" GraphRef="a11b7" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="2360.166666666664" Y="290.16666666666674" GraphRef="a11b7" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re10">
   <Interaction GraphId="re10">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="168" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="168" LineThickness="1.0">
-
       <Point X="1137.5" Y="782.5" GraphRef="sa13" RelX="0.5" RelY="-1.0" />
+
       <Point X="1137.5" Y="782.5" GraphRef="sa13" RelX="0.5" RelY="-1.0"/>
-
       <Point X="1137.5" Y="742.5" GraphRef="sa22" RelX="0.5" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="1137.5" Y="742.5" GraphRef="sa22" RelX="0.5" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re100">
   <Interaction GraphId="re100">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="169" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="169" LineThickness="1.0">
-
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1067.5" Y="2192.5" GraphRef="sa126" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="2192.5" GraphRef="sa126" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re101">
   <Interaction GraphId="re101">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="170" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="170" LineThickness="1.0">
-
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1067.5" Y="2242.5" GraphRef="sa127" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="2242.5" GraphRef="sa127" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re102">
   <Interaction GraphId="re102">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="171" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="171" LineThickness="1.0">
-
       <Point X="1147.5" Y="2142.5" GraphRef="sa125" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2142.5" GraphRef="sa125" RelX="1.0" RelY="0.0"/>
-
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re103">
   <Interaction GraphId="re103">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="172" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="172" LineThickness="1.0">
-
       <Point X="1147.5" Y="2192.5" GraphRef="sa126" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2192.5" GraphRef="sa126" RelX="1.0" RelY="0.0"/>
-
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re104">
   <Interaction GraphId="re104">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="173" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="173" LineThickness="1.0">
-
       <Point X="1147.5" Y="2242.5" GraphRef="sa127" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2242.5" GraphRef="sa127" RelX="1.0" RelY="0.0"/>
-
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1277.5" Y="2192.5" GraphRef="sa129" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re105">
   <Interaction GraphId="re105">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="174" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="174" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1357.5" Y="2192.5" GraphRef="sa129" RelX="1.0" RelY="0.0" />
+
       <Point X="1357.5" Y="2192.5" GraphRef="sa129" RelX="1.0" RelY="0.0"/>
-
       <Point X="1427.5" Y="2192.5" GraphRef="sa130" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1427.5" Y="2192.5" GraphRef="sa130" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re106">
   <Interaction GraphId="re106">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="175" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="175" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1167.5" Y="2322.5" GraphRef="sa121" RelX="1.0" RelY="0.0" />
+
       <Point X="1167.5" Y="2322.5" GraphRef="sa121" RelX="1.0" RelY="0.0"/>
-
       <Point X="1247.5" Y="2322.5" GraphRef="sa132" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1247.5" Y="2322.5" GraphRef="sa132" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re107">
   <Interaction GraphId="re107">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="176" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="176" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1327.5" Y="2322.5" GraphRef="sa132" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="2322.5" GraphRef="sa132" RelX="1.0" RelY="0.0"/>
-
       <Point X="1627.5" Y="2322.5" GraphRef="sa133" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1627.5" Y="2322.5" GraphRef="sa133" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re108">
   <Interaction GraphId="re108">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="177" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="177" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1847.5" Y="2322.5" GraphRef="sa133" RelX="1.0" RelY="0.0" />
+
       <Point X="1847.5" Y="2322.5" GraphRef="sa133" RelX="1.0" RelY="0.0"/>
-
       <Point X="2233.250000000002" Y="1677.8333333333348" GraphRef="a5031" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2233.250000000002" Y="1677.8333333333348" GraphRef="a5031" RelX="-0.5" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re109">
   <Interaction GraphId="re109">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="178" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="178" LineThickness="1.0">
-
       <Point X="957.5" Y="2452.5" GraphRef="sa135" RelX="0.0" RelY="1.0" />
+
       <Point X="957.5" Y="2452.5" GraphRef="sa135" RelX="0.0" RelY="1.0"/>
-
       <Point X="957.5" Y="2492.5" GraphRef="sa136" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="957.5" Y="2492.5" GraphRef="sa136" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="id10002">
   <Interaction GraphId="id10002">
-
     <Attribute Key="org.pathvisio.core.ds" Value="" />
+
     <Attribute Key="org.pathvisio.core.ds" Value=""/>
-
     <Attribute Key="org.pathvisio.core.id" Value="" />
+
     <Attribute Key="org.pathvisio.core.id" Value=""/>
     <Graphics ConnectorType="Segmented" ZOrder="179" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="179" LineThickness="1.0">
-
       <Point X="1267.5" Y="352.5" GraphRef="sa8" RelX="1.0" RelY="0.0" />
+
       <Point X="1267.5" Y="352.5" GraphRef="sa8" RelX="1.0" RelY="0.0"/>
-
       <Point X="1338.0" Y="353.0" GraphRef="id10001" RelX="0.5" RelY="0.004236983863847854" ArrowHead="mim-catalysis" />
+
       <Point X="1338.0" Y="353.0" GraphRef="id10001" RelX="0.5" RelY="0.004236983863847854" ArrowHead="mim-catalysis"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re11">
   <Interaction GraphId="re11">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="179" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="179" LineThickness="1.0">
-
       <Point X="1337.5" Y="382.5" GraphRef="sa25" RelX="-0.5" RelY="-1.0" />
+
       <Point X="1337.5" Y="382.5" GraphRef="sa25" RelX="-0.5" RelY="-1.0"/>
-
       <Point X="1337.5" Y="322.5" GraphRef="sa9" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1337.5" Y="322.5" GraphRef="sa9" RelX="-0.5" RelY="1.0" ArrowHead="Arrow"/>
-
       <Anchor Position="0.4917372830643976" Shape="None" GraphId="id10001" />
+
       <Anchor Position="0.4917372830643976" Shape="None" GraphId="id10001"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re110">
   <Interaction GraphId="re110">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="180" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="180" LineThickness="1.0">
-
       <Point X="813.5000000000001" Y="2512.5" GraphRef="sa134" RelX="0.6500000000000028" RelY="-1.0" />
+
       <Point X="813.5000000000001" Y="2512.5" GraphRef="sa134" RelX="0.6500000000000028" RelY="-1.0"/>
-
       <Point X="917.5" Y="2432.5" GraphRef="sa135" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2432.5" GraphRef="sa135" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re111">
   <Interaction GraphId="re111">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="181" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="181" LineThickness="1.0">
-
       <Point X="957.5" Y="2622.5" GraphRef="sa137" RelX="0.0" RelY="1.0" />
+
       <Point X="957.5" Y="2622.5" GraphRef="sa137" RelX="0.0" RelY="1.0"/>
-
       <Point X="957.5" Y="2652.5" GraphRef="sa138" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="957.5" Y="2652.5" GraphRef="sa138" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re112">
   <Interaction GraphId="re112">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="182" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="182" LineThickness="1.0">
-
       <Point X="823.2500000000013" Y="2551.749999999999" GraphRef="sa134" RelX="0.8937500000000312" RelY="0.9624999999999545" />
+
       <Point X="823.2500000000013" Y="2551.749999999999" GraphRef="sa134" RelX="0.8937500000000312" RelY="0.9624999999999545"/>
-
       <Point X="917.5" Y="2602.5" GraphRef="sa137" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2602.5" GraphRef="sa137" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re113">
   <Interaction GraphId="re113">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="183" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="183" LineThickness="1.0">
-
       <Point X="1107.5" Y="2453.75" GraphRef="sa140" RelX="0.0" RelY="1.0" />
+
       <Point X="1107.5" Y="2453.75" GraphRef="sa140" RelX="0.0" RelY="1.0"/>
-
       <Point X="1107.5" Y="2492.5" GraphRef="sa139" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1107.5" Y="2492.5" GraphRef="sa139" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re114">
   <Interaction GraphId="re114">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="184" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="184" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="997.5" Y="2512.5" GraphRef="sa136" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2512.5" GraphRef="sa136" RelX="1.0" RelY="0.0"/>
-
       <Point X="1081.25" Y="2443.125" GraphRef="sa140" RelX="-1.0" RelY="0.5" ArrowHead="Arrow" />
+
       <Point X="1081.25" Y="2443.125" GraphRef="sa140" RelX="-1.0" RelY="0.5" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re115">
   <Interaction GraphId="re115">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="185" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="185" LineThickness="1.0">
-
       <Point X="997.5" Y="2512.5" GraphRef="sa136" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2512.5" GraphRef="sa136" RelX="1.0" RelY="0.0"/>
-
       <Point X="1067.5" Y="2512.5" GraphRef="sa139" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="2512.5" GraphRef="sa139" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re116">
   <Interaction GraphId="re116">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="186" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="186" LineThickness="1.0">
-
       <Point X="1147.5" Y="2512.5" GraphRef="sa139" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2512.5" GraphRef="sa139" RelX="1.0" RelY="0.0"/>
-
       <Point X="1247.5" Y="2512.5" GraphRef="sa141" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1247.5" Y="2512.5" GraphRef="sa141" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re117">
   <Interaction GraphId="re117">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="187" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="187" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1327.5" Y="2512.5" GraphRef="sa141" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="2512.5" GraphRef="sa141" RelX="1.0" RelY="0.0"/>
-
       <Point X="2262.166666666669" Y="1677.8333333333348" GraphRef="a5031" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2262.166666666669" Y="1677.8333333333348" GraphRef="a5031" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re118">
   <Interaction GraphId="re118">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="188" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="188" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="997.5" Y="2672.5" GraphRef="sa138" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2672.5" GraphRef="sa138" RelX="1.0" RelY="0.0"/>
-
       <Point X="1070.0" Y="2680.0" GraphRef="sa174" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1070.0" Y="2680.0" GraphRef="sa174" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re119">
   <Interaction GraphId="re119">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="189" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="189" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1150.0" Y="2680.0" GraphRef="sa174" RelX="1.0" RelY="0.0" />
+
       <Point X="1150.0" Y="2680.0" GraphRef="sa174" RelX="1.0" RelY="0.0"/>
-
       <Point X="2358.6666666666665" Y="2387.0" />
+
       <Point X="2358.6666666666665" Y="2387.0"/>
-
       <Point X="2415.666666666672" Y="2094.0000000000005" GraphRef="f3965" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="2415.666666666672" Y="2094.0000000000005" GraphRef="f3965" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re12">
   <Interaction GraphId="re12">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="190" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="190" LineThickness="1.0">
-
       <Point X="1000.5" Y="544.0" GraphRef="sa14" RelX="1.0" RelY="-0.5" />
+
       <Point X="1000.5" Y="544.0" GraphRef="sa14" RelX="1.0" RelY="-0.5"/>
-
       <Point X="1057.5" Y="502.5" GraphRef="sa11" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1057.5" Y="502.5" GraphRef="sa11" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re120">
   <Interaction GraphId="re120">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="191" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="191" LineThickness="1.0">
-
       <Point X="827.5" Y="2792.5" GraphRef="sa143" RelX="1.0" RelY="0.0" />
+
       <Point X="827.5" Y="2792.5" GraphRef="sa143" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="2792.5" GraphRef="sa145" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2792.5" GraphRef="sa145" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re121">
   <Interaction GraphId="re121">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="192" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="192" LineThickness="1.0">
-
       <Point X="997.5" Y="2862.5" GraphRef="sa147" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2862.5" GraphRef="sa147" RelX="1.0" RelY="0.0"/>
-
       <Point X="1081.25" Y="2862.5" GraphRef="sa146" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1081.25" Y="2862.5" GraphRef="sa146" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re122">
   <Interaction GraphId="re122">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="193" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="193" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="997.5" Y="2792.5" GraphRef="sa144" RelX="1.0" RelY="1.0" />
+
       <Point X="997.5" Y="2792.5" GraphRef="sa144" RelX="1.0" RelY="1.0"/>
-
       <Point X="1081.25" Y="2851.875" GraphRef="sa146" RelX="-1.0" RelY="-0.5" ArrowHead="Arrow" />
+
       <Point X="1081.25" Y="2851.875" GraphRef="sa146" RelX="-1.0" RelY="-0.5" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re123">
   <Interaction GraphId="re123">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="194" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="194" LineThickness="1.0">
-
       <Point X="1128.75" Y="2862.5" GraphRef="sa146" RelX="0.8095238095238095" RelY="0.0" />
+
       <Point X="1128.75" Y="2862.5" GraphRef="sa146" RelX="0.8095238095238095" RelY="0.0"/>
-
       <Point X="1247.5" Y="2862.5" GraphRef="sa148" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1247.5" Y="2862.5" GraphRef="sa148" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re124">
   <Interaction GraphId="re124">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="195" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="195" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1327.5" Y="2862.5" GraphRef="sa148" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="2862.5" GraphRef="sa148" RelX="1.0" RelY="0.0"/>
-
       <Point X="2444.5833333333385" Y="2106.5000000000005" GraphRef="f3965" RelX="-0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2444.5833333333385" Y="2106.5000000000005" GraphRef="f3965" RelX="-0.5" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re125">
   <Interaction GraphId="re125">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="196" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="196" LineThickness="1.0">
-
       <Point X="827.5" Y="2972.5" GraphRef="sa149" RelX="1.0" RelY="0.0" />
+
       <Point X="827.5" Y="2972.5" GraphRef="sa149" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="2972.5" GraphRef="sa150" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2972.5" GraphRef="sa150" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re126">
   <Interaction GraphId="re126">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="197" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="197" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="997.5" Y="2972.5" GraphRef="sa150" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2972.5" GraphRef="sa150" RelX="1.0" RelY="0.0"/>
-
       <Point X="1067.5" Y="2972.5" GraphRef="sa151" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1067.5" Y="2972.5" GraphRef="sa151" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re127">
   <Interaction GraphId="re127">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="198" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="198" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1147.5" Y="2972.5" GraphRef="sa151" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2972.5" GraphRef="sa151" RelX="1.0" RelY="0.0"/>
-
       <Point X="1247.5" Y="2972.5" GraphRef="sa152" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1247.5" Y="2972.5" GraphRef="sa152" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re128">
   <Interaction GraphId="re128">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="199" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="199" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1327.5" Y="2972.5" GraphRef="sa152" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="2972.5" GraphRef="sa152" RelX="1.0" RelY="0.0"/>
-
       <Point X="1417.5" Y="2972.5" GraphRef="sa153" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1417.5" Y="2972.5" GraphRef="sa153" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re129">
   <Interaction GraphId="re129">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="200" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="200" LineThickness="1.0">
-
       <Point X="1497.5" Y="2972.5" GraphRef="sa153" RelX="1.0" RelY="0.0" />
+
       <Point X="1497.5" Y="2972.5" GraphRef="sa153" RelX="1.0" RelY="0.0"/>
-
       <Point X="1597.0008919280708" Y="2970.0731489773643" GraphRef="sa175" RelX="-1.0749777017982296" RelY="0.0036574488682163064" ArrowHead="mim-inhibition" />
+
       <Point X="1597.0008919280708" Y="2970.0731489773643" GraphRef="sa175" RelX="-1.0749777017982296" RelY="0.0036574488682163064" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re13">
   <Interaction GraphId="re13">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="201" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="201" LineThickness="1.0">
-
       <Point X="1000.5" Y="544.0" GraphRef="sa14" RelX="1.0" RelY="-0.5" />
+
       <Point X="1000.5" Y="544.0" GraphRef="sa14" RelX="1.0" RelY="-0.5"/>
-
       <Point X="1056.5" Y="543.5" GraphRef="sa12" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification" />
+
       <Point X="1056.5" Y="543.5" GraphRef="sa12" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re130">
   <Interaction GraphId="re130">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="202" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="202" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1680.0" Y="2970.0" GraphRef="sa175" RelX="1.0" RelY="0.0" />
+
       <Point X="1680.0" Y="2970.0" GraphRef="sa175" RelX="1.0" RelY="0.0"/>
-
       <Point X="2473.5000000000055" Y="2106.5000000000005" GraphRef="f3965" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2473.5000000000055" Y="2106.5000000000005" GraphRef="f3965" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re131">
   <Interaction GraphId="re131">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="203" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="203" LineThickness="1.0">
-
       <Point X="997.5" Y="3092.5" GraphRef="sa157" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="3092.5" GraphRef="sa157" RelX="1.0" RelY="0.0"/>
-
       <Point X="1071.9166666666677" Y="3091.1666666666656" GraphRef="sa158" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1071.9166666666677" Y="3091.1666666666656" GraphRef="sa158" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re132">
   <Interaction GraphId="re132">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="204" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="204" LineThickness="1.0">
-
       <Point X="1119.4166666666677" Y="3091.1666666666656" GraphRef="sa158" RelX="0.8095238095238095" RelY="0.0" />
+
       <Point X="1119.4166666666677" Y="3091.1666666666656" GraphRef="sa158" RelX="0.8095238095238095" RelY="0.0"/>
-
       <Point X="1247.5" Y="3092.5" GraphRef="sa159" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1247.5" Y="3092.5" GraphRef="sa159" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re133">
   <Interaction GraphId="re133">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="205" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="205" LineThickness="1.0">
-
       <Point X="937.5" Y="3172.5" GraphRef="sa160" RelX="-0.5" RelY="-1.0" />
+
       <Point X="937.5" Y="3172.5" GraphRef="sa160" RelX="-0.5" RelY="-1.0"/>
-
       <Point X="937.5" Y="3112.5" GraphRef="sa157" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="937.5" Y="3112.5" GraphRef="sa157" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re134">
   <Interaction GraphId="re134">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="206" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="206" LineThickness="1.0">
-
       <Point X="957.5" Y="3112.5" GraphRef="sa157" RelX="0.0" RelY="1.0" />
+
       <Point X="957.5" Y="3112.5" GraphRef="sa157" RelX="0.0" RelY="1.0"/>
-
       <Point X="957.5" Y="3172.5" GraphRef="sa160" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="957.5" Y="3172.5" GraphRef="sa160" RelX="0.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re135">
   <Interaction GraphId="re135">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="207" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="207" LineThickness="1.0">
-
       <Point X="827.5" Y="3212.5" GraphRef="sa163" RelX="1.0" RelY="-1.0" />
+
       <Point X="827.5" Y="3212.5" GraphRef="sa163" RelX="1.0" RelY="-1.0"/>
-
       <Point X="917.5" Y="3212.5" GraphRef="sa161" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="3212.5" GraphRef="sa161" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re136">
   <Interaction GraphId="re136">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="208" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="208" LineThickness="1.0">
-
       <Point X="1327.5" Y="3092.5" GraphRef="sa159" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="3092.5" GraphRef="sa159" RelX="1.0" RelY="0.0"/>
-
       <Point X="1417.5" Y="3092.5" GraphRef="sa165" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1417.5" Y="3092.5" GraphRef="sa165" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re137">
   <Interaction GraphId="re137">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="209" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="209" LineThickness="1.0">
-
       <Point X="1497.5" Y="3092.5" GraphRef="sa165" RelX="1.0" RelY="0.0" />
+
       <Point X="1497.5" Y="3092.5" GraphRef="sa165" RelX="1.0" RelY="0.0"/>
-
       <Point X="1607.5" Y="3092.5" GraphRef="sa166" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1607.5" Y="3092.5" GraphRef="sa166" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re138">
   <Interaction GraphId="re138">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="210" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="210" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1687.5" Y="3092.5" GraphRef="sa166" RelX="1.0" RelY="0.0" />
+
       <Point X="1687.5" Y="3092.5" GraphRef="sa166" RelX="1.0" RelY="0.0"/>
-
       <Point X="2291.0833333333358" Y="1677.8333333333348" GraphRef="a5031" RelX="0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2291.0833333333358" Y="1677.8333333333348" GraphRef="a5031" RelX="0.5" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re139">
   <Interaction GraphId="re139">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="211" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="211" LineThickness="1.0">
-
       <Point X="997.5" Y="3212.5" GraphRef="sa161" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="3212.5" GraphRef="sa161" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1077.5" Y="3212.5" GraphRef="sa168" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1077.5" Y="3212.5" GraphRef="sa168" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re14">
   <Interaction GraphId="re14">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="212" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="212" LineThickness="1.0">
-
       <Point X="1056.5" Y="563.5" GraphRef="sa12" RelX="-1.0" RelY="0.5" />
+
       <Point X="1056.5" Y="563.5" GraphRef="sa12" RelX="-1.0" RelY="0.5"/>
-
       <Point X="1000.5" Y="567.0" GraphRef="sa14" RelX="1.0" RelY="0.5" ArrowHead="mim-modification" />
+
       <Point X="1000.5" Y="567.0" GraphRef="sa14" RelX="1.0" RelY="0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re140">
   <Interaction GraphId="re140">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="213" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="213" LineThickness="1.0">
-
       <Point X="1157.5" Y="3212.5" GraphRef="sa168" RelX="1.0" RelY="0.0" />
+
       <Point X="1157.5" Y="3212.5" GraphRef="sa168" RelX="1.0" RelY="0.0"/>
-
       <Point X="1244.5" Y="3212.5" GraphRef="sa169" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition" />
+
       <Point X="1244.5" Y="3212.5" GraphRef="sa169" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re141">
   <Interaction GraphId="re141">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="214" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="214" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1327.5" Y="3212.5" GraphRef="sa169" RelX="1.0" RelY="0.0" />
+
       <Point X="1327.5" Y="3212.5" GraphRef="sa169" RelX="1.0" RelY="0.0"/>
-
       <Point X="1813.5000000000011" Y="3215.1666666666665" GraphRef="f96a7" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1813.5000000000011" Y="3215.1666666666665" GraphRef="f96a7" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re142">
   <Interaction GraphId="re142">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="215" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="215" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="2033.5000000000011" Y="3215.1666666666665" GraphRef="f96a7" RelX="1.0" RelY="0.0" />
+
       <Point X="2033.5000000000011" Y="3215.1666666666665" GraphRef="f96a7" RelX="1.0" RelY="0.0"/>
-
       <Point X="2502.4166666666724" Y="2106.5000000000005" GraphRef="f3965" RelX="0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="2502.4166666666724" Y="2106.5000000000005" GraphRef="f3965" RelX="0.5" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re143">
   <Interaction GraphId="re143">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="216" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="216" LineThickness="1.0">
-
       <Point X="457.5" Y="1312.5" GraphRef="sa77" RelX="0.0" RelY="1.0" />
+
       <Point X="457.5" Y="1312.5" GraphRef="sa77" RelX="0.0" RelY="1.0"/>
-
       <Point X="457.5" Y="1389.5" GraphRef="sa78" RelX="0.0" RelY="-1.15" ArrowHead="mim-inhibition" />
+
       <Point X="457.5" Y="1389.5" GraphRef="sa78" RelX="0.0" RelY="-1.15" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re144">
   <Interaction GraphId="re144">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="217" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="217" LineThickness="1.0">
-
       <Point X="1447.5" Y="1172.5" GraphRef="sa54" RelX="1.0" RelY="0.0" />
+
       <Point X="1447.5" Y="1172.5" GraphRef="sa54" RelX="1.0" RelY="0.0"/>
-
       <Point X="1896.5" Y="1199.5" GraphRef="ae2d7" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1896.5" Y="1199.5" GraphRef="ae2d7" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re145">
   <Interaction GraphId="re145">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="218" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="218" LineThickness="1.0">
-
       <Point X="1447.5" Y="1252.5" GraphRef="sa69" RelX="1.0" RelY="0.0" />
+
       <Point X="1447.5" Y="1252.5" GraphRef="sa69" RelX="1.0" RelY="0.0"/>
-
       <Point X="1896.5" Y="1229.5" GraphRef="ae2d7" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="1896.5" Y="1229.5" GraphRef="ae2d7" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re146">
   <Interaction GraphId="re146">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="219" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="219" LineThickness="1.0">
-
       <Point X="1150.0" Y="1570.0" GraphRef="sa91" RelX="1.0" RelY="0.0" />
+
       <Point X="1150.0" Y="1570.0" GraphRef="sa91" RelX="1.0" RelY="0.0"/>
-
       <Point X="1330.0" Y="1570.0" />
+
       <Point X="1330.0" Y="1570.0"/>
-
       <Point X="1330.0" Y="1530.0" />
+
       <Point X="1330.0" Y="1530.0"/>
-
       <Point X="1367.0" Y="1530.0" GraphRef="sa172" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition" />
+
       <Point X="1367.0" Y="1530.0" GraphRef="sa172" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re147">
   <Interaction GraphId="re147">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ZOrder="220" LineStyle="Broken" LineThickness="1.0">
     <Graphics ZOrder="220" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1450.0" Y="1530.0" GraphRef="sa172" RelX="1.0" RelY="0.0" />
+
       <Point X="1450.0" Y="1530.0" GraphRef="sa172" RelX="1.0" RelY="0.0"/>
-
       <Point X="1780.4166666666665" Y="1530.7500000000007" GraphRef="b3d54" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1780.4166666666665" Y="1530.7500000000007" GraphRef="b3d54" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re148">
   <Interaction GraphId="re148">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="221" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="221" LineThickness="1.0">
-
       <Point X="1430.0" Y="1980.0" GraphRef="sa173" RelX="0.0" RelY="-1.0" />
+
       <Point X="1430.0" Y="1980.0" GraphRef="sa173" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1427.5" Y="1952.5" GraphRef="sa111" RelX="0.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="1427.5" Y="1952.5" GraphRef="sa111" RelX="0.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re149">
   <Interaction GraphId="re149">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="222" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="222" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1467.5" Y="1832.5" GraphRef="sa101" RelX="1.0" RelY="0.0" />
+
       <Point X="1467.5" Y="1832.5" GraphRef="sa101" RelX="1.0" RelY="0.0"/>
-
       <Point X="1942.3541666666667" Y="1543.2500000000007" GraphRef="b3d54" RelX="0.5" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1942.3541666666667" Y="1543.2500000000007" GraphRef="b3d54" RelX="0.5" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re15">
   <Interaction GraphId="re15">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="223" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="223" LineThickness="1.0">
-
       <Point X="1000.5" Y="567.0" GraphRef="sa14" RelX="1.0" RelY="0.5" />
+
       <Point X="1000.5" Y="567.0" GraphRef="sa14" RelX="1.0" RelY="0.5"/>
-
       <Point X="1057.5" Y="612.5" GraphRef="sa23" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1057.5" Y="612.5" GraphRef="sa23" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re150">
   <Interaction GraphId="re150">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="224" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="224" LineThickness="1.0">
-
       <Point X="1267.5" Y="1502.5" GraphRef="sa90" RelX="0.0" RelY="-1.0" />
+
       <Point X="1267.5" Y="1502.5" GraphRef="sa90" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1268.0" Y="1462.0" />
+
       <Point X="1268.0" Y="1462.0"/>
-
       <Point X="1834.0" Y="1463.0" />
+
       <Point X="1834.0" Y="1463.0"/>
-
       <Point X="1834.3958333333333" Y="1518.2500000000007" GraphRef="b3d54" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1834.3958333333333" Y="1518.2500000000007" GraphRef="b3d54" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re16">
   <Interaction GraphId="re16">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="225" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="225" LineThickness="1.0">
-
       <Point X="1237.5" Y="512.5" GraphRef="sa28" RelX="0.0" RelY="-1.0" />
+
       <Point X="1237.5" Y="512.5" GraphRef="sa28" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1237.5" Y="485.5" GraphRef="sa29" RelX="0.0" RelY="1.15" ArrowHead="mim-inhibition" />
+
       <Point X="1237.5" Y="485.5" GraphRef="sa29" RelX="0.0" RelY="1.15" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re17">
   <Interaction GraphId="re17">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="226" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="226" LineThickness="1.0">
-
       <Point X="1277.5" Y="462.5" GraphRef="sa29" RelX="1.0" RelY="0.0" />
+
       <Point X="1277.5" Y="462.5" GraphRef="sa29" RelX="1.0" RelY="0.0"/>
-
       <Point X="1317.5" Y="462.5" GraphRef="sa30" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1317.5" Y="462.5" GraphRef="sa30" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re18">
   <Interaction GraphId="re18">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="227" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="227" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1397.5" Y="462.5" GraphRef="sa30" RelX="1.0" RelY="0.0" />
+
       <Point X="1397.5" Y="462.5" GraphRef="sa30" RelX="1.0" RelY="0.0"/>
-
       <Point X="1539.0000000000005" Y="462.6666666666668" GraphRef="b0cf2" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1539.0000000000005" Y="462.6666666666668" GraphRef="b0cf2" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re19">
   <Interaction GraphId="re19">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="228" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="228" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1698.7500000000005" Y="475.1666666666668" GraphRef="b0cf2" RelX="0.5" RelY="1.0" />
+
       <Point X="1698.7500000000005" Y="475.1666666666668" GraphRef="b0cf2" RelX="0.5" RelY="1.0"/>
-
       <Point X="1699.0" Y="726.0" />
+
       <Point X="1699.0" Y="726.0"/>
-
       <Point X="2509.0" Y="733.0" />
+
       <Point X="2509.0" Y="733.0"/>
-
       <Point X="2502.4166666666724" Y="2081.5000000000005" GraphRef="f3965" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="2502.4166666666724" Y="2081.5000000000005" GraphRef="f3965" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re2">
   <Interaction GraphId="re2">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="229" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="229" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1000.0" Y="210.0" GraphRef="sa2" RelX="1.0" RelY="-0.5" />
+
       <Point X="1000.0" Y="210.0" GraphRef="sa2" RelX="1.0" RelY="-0.5"/>
-
       <Point X="2330.2499999999973" Y="290.16666666666674" GraphRef="a11b7" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="2330.2499999999973" Y="290.16666666666674" GraphRef="a11b7" RelX="-0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re20">
   <Interaction GraphId="re20">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="230" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="230" LineThickness="1.0">
-
       <Point X="1380.0" Y="590.0" GraphRef="sa170" RelX="-1.0" RelY="-1.0" />
+
       <Point X="1380.0" Y="590.0" GraphRef="sa170" RelX="-1.0" RelY="-1.0"/>
-
       <Point X="1217.5" Y="612.5" GraphRef="sa26" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1217.5" Y="612.5" GraphRef="sa26" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re21">
   <Interaction GraphId="re21">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="231" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="231" LineThickness="1.0">
-
       <Point X="1277.5" Y="552.5" GraphRef="sa28" RelX="1.0" RelY="1.0" />
+
       <Point X="1277.5" Y="552.5" GraphRef="sa28" RelX="1.0" RelY="1.0"/>
-
       <Point X="1380.0" Y="590.0" GraphRef="sa170" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1380.0" Y="590.0" GraphRef="sa170" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re22">
   <Interaction GraphId="re22">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="232" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="232" LineThickness="1.0">
-
       <Point X="1136.5" Y="553.5" GraphRef="sa12" RelX="1.0" RelY="0.0" />
+
       <Point X="1136.5" Y="553.5" GraphRef="sa12" RelX="1.0" RelY="0.0"/>
-
       <Point X="1197.5" Y="552.5" GraphRef="sa27" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1197.5" Y="552.5" GraphRef="sa27" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re23">
   <Interaction GraphId="re23">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="233" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="233" LineThickness="1.0">
-
       <Point X="1460.0" Y="590.0" GraphRef="sa170" RelX="1.0" RelY="-1.0" />
+
       <Point X="1460.0" Y="590.0" GraphRef="sa170" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1516.5" Y="590.5" GraphRef="sa35" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1516.5" Y="590.5" GraphRef="sa35" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re24">
   <Interaction GraphId="re24">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="234" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="234" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1596.5" Y="590.5" GraphRef="sa35" RelX="1.0" RelY="0.0" />
+
       <Point X="1596.5" Y="590.5" GraphRef="sa35" RelX="1.0" RelY="0.0"/>
-
       <Point X="1645.5000000000005" Y="475.1666666666668" GraphRef="b0cf2" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1645.5000000000005" Y="475.1666666666668" GraphRef="b0cf2" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re25">
   <Interaction GraphId="re25">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="235" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="235" LineThickness="1.0">
-
       <Point X="826.9545454545452" Y="642.5" GraphRef="sa16" RelX="0.4863636363636289" RelY="-1.0" />
+
       <Point X="826.9545454545452" Y="642.5" GraphRef="sa16" RelX="0.4863636363636289" RelY="-1.0"/>
-
       <Point X="914.5" Y="552.5" GraphRef="sa14" RelX="-1.0" RelY="-0.13043478260869565" ArrowHead="mim-modification" />
+
       <Point X="914.5" Y="552.5" GraphRef="sa14" RelX="-1.0" RelY="-0.13043478260869565" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re26">
   <Interaction GraphId="re26">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="236" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="236" LineThickness="1.0">
-
       <Point X="825.8333333333329" Y="682.5" GraphRef="sa16" RelX="0.45833333333332293" RelY="1.0" />
+
       <Point X="825.8333333333329" Y="682.5" GraphRef="sa16" RelX="0.45833333333332293" RelY="1.0"/>
-
       <Point X="917.5" Y="782.5" GraphRef="sa19" RelX="-1.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="782.5" GraphRef="sa19" RelX="-1.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re27">
   <Interaction GraphId="re27">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="237" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="237" LineThickness="1.0">
-
       <Point X="1077.5" Y="722.5" GraphRef="sa22" RelX="-1.0" RelY="0.0" />
+
       <Point X="1077.5" Y="722.5" GraphRef="sa22" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="762.5" GraphRef="sa19" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="762.5" GraphRef="sa19" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re28">
   <Interaction GraphId="re28">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="238" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="238" LineThickness="1.0">
-
       <Point X="1077.5" Y="722.5" GraphRef="sa22" RelX="-1.0" RelY="0.0" />
+
       <Point X="1077.5" Y="722.5" GraphRef="sa22" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="802.5" GraphRef="sa15" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="802.5" GraphRef="sa15" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re29">
   <Interaction GraphId="re29">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="239" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="239" LineThickness="1.0">
-
       <Point X="1077.5" Y="802.5" GraphRef="sa13" RelX="-1.0" RelY="0.0" />
+
       <Point X="1077.5" Y="802.5" GraphRef="sa13" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="762.5" GraphRef="sa19" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="762.5" GraphRef="sa19" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re3">
   <Interaction GraphId="re3">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="240" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="240" LineThickness="1.0">
-
       <Point X="1007.5" Y="352.5" GraphRef="sa3" RelX="1.0" RelY="0.0" />
+
       <Point X="1007.5" Y="352.5" GraphRef="sa3" RelX="1.0" RelY="0.0"/>
-
       <Point X="1071.25" Y="352.4999999999999" GraphRef="sa7" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1071.25" Y="352.4999999999999" GraphRef="sa7" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re30">
   <Interaction GraphId="re30">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="241" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="241" LineThickness="1.0">
-
       <Point X="1077.5" Y="802.5" GraphRef="sa13" RelX="-1.0" RelY="0.0" />
+
       <Point X="1077.5" Y="802.5" GraphRef="sa13" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="802.5" GraphRef="sa15" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="802.5" GraphRef="sa15" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re31">
   <Interaction GraphId="re31">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="242" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="242" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1165.5" Y="762.5" GraphRef="bbfa1" RelX="1.0" RelY="0.0" />
+
       <Point X="1165.5" Y="762.5" GraphRef="bbfa1" RelX="1.0" RelY="0.0"/>
-
       <Point X="2291.0833333333358" Y="1652.8333333333348" GraphRef="a5031" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="2291.0833333333358" Y="1652.8333333333348" GraphRef="a5031" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re32">
   <Interaction GraphId="re32">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="243" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="243" LineThickness="1.0">
-
       <Point X="817.5" Y="932.5" GraphRef="sa40" RelX="1.0" RelY="0.0" />
+
       <Point X="817.5" Y="932.5" GraphRef="sa40" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="932.5" GraphRef="sa38" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="932.5" GraphRef="sa38" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re33">
   <Interaction GraphId="re33">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="244" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="244" LineThickness="1.0">
-
       <Point X="957.5" Y="1002.5" GraphRef="sa39" RelX="0.0" RelY="-1.0" />
+
       <Point X="957.5" Y="1002.5" GraphRef="sa39" RelX="0.0" RelY="-1.0"/>
-
       <Point X="957.5" Y="952.5" GraphRef="sa38" RelX="0.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="957.5" Y="952.5" GraphRef="sa38" RelX="0.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re34">
   <Interaction GraphId="re34">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="245" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="245" LineThickness="1.0">
-
       <Point X="808.611111111111" Y="952.4999999999999" GraphRef="sa40" RelX="0.7777777777777743" RelY="0.9999999999999943" />
+
       <Point X="808.611111111111" Y="952.4999999999999" GraphRef="sa40" RelX="0.7777777777777743" RelY="0.9999999999999943"/>
-
       <Point X="914.9764645738703" Y="1020.8777272260595" GraphRef="sa39" RelX="-1.063088385653242" RelY="-0.08111363869702473" ArrowHead="mim-inhibition" />
+
       <Point X="914.9764645738703" Y="1020.8777272260595" GraphRef="sa39" RelX="-1.063088385653242" RelY="-0.08111363869702473" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re35">
   <Interaction GraphId="re35">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="246" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="246" LineThickness="1.0">
-
       <Point X="997.5" Y="932.5" GraphRef="sa38" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="932.5" GraphRef="sa38" RelX="1.0" RelY="0.0"/>
-
       <Point X="1117.5" Y="932.5" GraphRef="sa41" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1117.5" Y="932.5" GraphRef="sa41" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re36">
   <Interaction GraphId="re36">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="247" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="247" LineThickness="1.0">
-
       <Point X="1337.5" Y="932.5" GraphRef="sa43" RelX="1.0" RelY="0.0" />
+
       <Point X="1337.5" Y="932.5" GraphRef="sa43" RelX="1.0" RelY="0.0"/>
-
       <Point X="1377.5" Y="932.5" GraphRef="sa44" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1377.5" Y="932.5" GraphRef="sa44" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re37">
   <Interaction GraphId="re37">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="248" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="248" LineThickness="1.0">
-
       <Point X="1197.5" Y="932.5" GraphRef="sa41" RelX="1.0" RelY="0.0" />
+
       <Point X="1197.5" Y="932.5" GraphRef="sa41" RelX="1.0" RelY="0.0"/>
-
       <Point X="1257.5" Y="932.5" GraphRef="sa43" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1257.5" Y="932.5" GraphRef="sa43" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re38">
   <Interaction GraphId="re38">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="249" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="249" LineThickness="1.0">
-
       <Point X="1457.5" Y="932.5" GraphRef="sa44" RelX="1.0" RelY="0.0" />
+
       <Point X="1457.5" Y="932.5" GraphRef="sa44" RelX="1.0" RelY="0.0"/>
-
       <Point X="1507.5" Y="932.5" GraphRef="sa45" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1507.5" Y="932.5" GraphRef="sa45" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re39">
   <Interaction GraphId="re39">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="250" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="250" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1587.5" Y="932.5" GraphRef="sa45" RelX="1.0" RelY="0.0" />
+
       <Point X="1587.5" Y="932.5" GraphRef="sa45" RelX="1.0" RelY="0.0"/>
-
       <Point X="2330.2499999999973" Y="315.16666666666674" GraphRef="a11b7" RelX="-0.5" RelY="1.0" ArrowHead="mim-inhibition" />
+
       <Point X="2330.2499999999973" Y="315.16666666666674" GraphRef="a11b7" RelX="-0.5" RelY="1.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re4">
   <Interaction GraphId="re4">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ZOrder="251" LineStyle="Broken" LineThickness="1.0">
     <Graphics ZOrder="251" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1557.0000000000011" Y="302.6666666666669" GraphRef="a88fa" RelX="1.0" RelY="0.0" />
+
       <Point X="1557.0000000000011" Y="302.6666666666669" GraphRef="a88fa" RelX="1.0" RelY="0.0"/>
-
       <Point X="2300.3333333333303" Y="302.66666666666674" GraphRef="a11b7" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="2300.3333333333303" Y="302.66666666666674" GraphRef="a11b7" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re40">
   <Interaction GraphId="re40">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="252" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="252" LineThickness="1.0">
-
       <Point X="1157.5" Y="1102.5" GraphRef="sa48" RelX="1.0" RelY="0.0" />
+
       <Point X="1157.5" Y="1102.5" GraphRef="sa48" RelX="1.0" RelY="0.0"/>
-
       <Point X="1217.5" Y="1102.5" GraphRef="sa52" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1217.5" Y="1102.5" GraphRef="sa52" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re41">
   <Interaction GraphId="re41">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="253" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="253" LineThickness="1.0">
-
       <Point X="1160.0" Y="1172.0" GraphRef="sa50" RelX="1.0" RelY="0.0" />
+
       <Point X="1160.0" Y="1172.0" GraphRef="sa50" RelX="1.0" RelY="0.0"/>
-
       <Point X="1213.502831524935" Y="1172.3696883271712" GraphRef="sa53" RelX="-1.0749292118766278" RelY="-0.006515583641441935" ArrowHead="mim-inhibition" />
+
       <Point X="1213.502831524935" Y="1172.3696883271712" GraphRef="sa53" RelX="-1.0749292118766278" RelY="-0.006515583641441935" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re42">
   <Interaction GraphId="re42">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="254" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="254" LineThickness="1.0">
-
       <Point X="1296.5" Y="1172.5" GraphRef="sa53" RelX="1.0" RelY="0.0" />
+
       <Point X="1296.5" Y="1172.5" GraphRef="sa53" RelX="1.0" RelY="0.0"/>
-
       <Point X="1367.5" Y="1172.5" GraphRef="sa54" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1367.5" Y="1172.5" GraphRef="sa54" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re43">
   <Interaction GraphId="re43">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="255" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="255" LineThickness="1.0">
-
       <Point X="1297.5" Y="1332.5" GraphRef="sa58" RelX="1.0" RelY="0.0" />
+
       <Point X="1297.5" Y="1332.5" GraphRef="sa58" RelX="1.0" RelY="0.0"/>
-
       <Point X="1367.5" Y="1332.5" GraphRef="sa59" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1367.5" Y="1332.5" GraphRef="sa59" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re44">
   <Interaction GraphId="re44">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="256" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="256" LineThickness="1.0">
-
       <Point X="1157.5" Y="1252.5" GraphRef="sa51" RelX="1.0" RelY="0.0" />
+
       <Point X="1157.5" Y="1252.5" GraphRef="sa51" RelX="1.0" RelY="0.0"/>
-
       <Point X="1214.5" Y="1252.5" GraphRef="sa57" RelX="-1.075" RelY="-1.0" ArrowHead="mim-inhibition" />
+
       <Point X="1214.5" Y="1252.5" GraphRef="sa57" RelX="-1.075" RelY="-1.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re45">
   <Interaction GraphId="re45">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="257" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="257" LineThickness="1.0">
-
       <Point X="1157.5" Y="1272.5" GraphRef="sa51" RelX="1.0" RelY="1.0" />
+
       <Point X="1157.5" Y="1272.5" GraphRef="sa51" RelX="1.0" RelY="1.0"/>
-
       <Point X="1217.5" Y="1332.5" GraphRef="sa58" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1217.5" Y="1332.5" GraphRef="sa58" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re46">
   <Interaction GraphId="re46">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="258" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="258" LineThickness="1.0">
-
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0" />
+
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0"/>
-
       <Point X="1077.5" Y="1102.5" GraphRef="sa48" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1077.5" Y="1102.5" GraphRef="sa48" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re47">
   <Interaction GraphId="re47">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="259" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="259" LineThickness="1.0">
-
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0" />
+
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0"/>
-
       <Point X="1080.0" Y="1172.0" GraphRef="sa50" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1080.0" Y="1172.0" GraphRef="sa50" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re48">
   <Interaction GraphId="re48">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="260" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="260" LineThickness="1.0">
-
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0" />
+
       <Point X="1010.0" Y="1172.5" GraphRef="sa60" RelX="1.0" RelY="0.0"/>
-
       <Point X="1077.5" Y="1252.5" GraphRef="sa51" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1077.5" Y="1252.5" GraphRef="sa51" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re49">
   <Interaction GraphId="re49">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="261" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="261" LineThickness="1.0">
-
       <Point X="637.5" Y="1142.5" GraphRef="sa61" RelX="1.0" RelY="-0.5" />
+
       <Point X="637.5" Y="1142.5" GraphRef="sa61" RelX="1.0" RelY="-0.5"/>
-
       <Point X="917.5" Y="1142.5" GraphRef="sa46" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="1142.5" GraphRef="sa46" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re5">
   <Interaction GraphId="re5">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="262" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="262" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1397.5" Y="302.5" GraphRef="sa9" RelX="1.0" RelY="0.0" />
+
       <Point X="1397.5" Y="302.5" GraphRef="sa9" RelX="1.0" RelY="0.0"/>
-
       <Point X="1467.0000000000011" Y="302.6666666666669" GraphRef="a88fa" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1467.0000000000011" Y="302.6666666666669" GraphRef="a88fa" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re50">
   <Interaction GraphId="re50">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="263" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="263" LineThickness="1.0">
-
       <Point X="917.5" Y="1162.5" GraphRef="sa46" RelX="-1.0" RelY="0.5" />
+
       <Point X="917.5" Y="1162.5" GraphRef="sa46" RelX="-1.0" RelY="0.5"/>
-
       <Point X="637.5" Y="1162.5" GraphRef="sa61" RelX="1.0" RelY="0.5" ArrowHead="mim-modification" />
+
       <Point X="637.5" Y="1162.5" GraphRef="sa61" RelX="1.0" RelY="0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re51">
   <Interaction GraphId="re51">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="264" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="264" LineThickness="1.0">
-
       <Point X="637.5" Y="1192.5" GraphRef="sa62" RelX="1.0" RelY="-0.5" />
+
       <Point X="637.5" Y="1192.5" GraphRef="sa62" RelX="1.0" RelY="-0.5"/>
-
       <Point X="917.5" Y="1192.5" GraphRef="sa47" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="1192.5" GraphRef="sa47" RelX="-1.0" RelY="-0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re52">
   <Interaction GraphId="re52">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="265" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="265" LineThickness="1.0">
-
       <Point X="917.5" Y="1212.5" GraphRef="sa47" RelX="-1.0" RelY="0.5" />
+
       <Point X="917.5" Y="1212.5" GraphRef="sa47" RelX="-1.0" RelY="0.5"/>
-
       <Point X="637.5" Y="1212.5" GraphRef="sa62" RelX="1.0" RelY="0.5" ArrowHead="mim-modification" />
+
       <Point X="637.5" Y="1212.5" GraphRef="sa62" RelX="1.0" RelY="0.5" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re53">
   <Interaction GraphId="re53">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="266" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="266" LineThickness="1.0">
-
       <Point X="737.5" Y="1412.5" GraphRef="sa66" RelX="-1.0" RelY="0.0" />
+
       <Point X="737.5" Y="1412.5" GraphRef="sa66" RelX="-1.0" RelY="0.0"/>
-
       <Point X="637.5" Y="1412.5" GraphRef="sa63" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="637.5" Y="1412.5" GraphRef="sa63" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re54">
   <Interaction GraphId="re54">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="267" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="267" LineThickness="1.0">
-
       <Point X="817.5" Y="1412.5" GraphRef="sa66" RelX="1.0" RelY="0.0" />
+
       <Point X="817.5" Y="1412.5" GraphRef="sa66" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="1412.5" GraphRef="sa65" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="1412.5" GraphRef="sa65" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re55">
   <Interaction GraphId="re55">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="268" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="268" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1941.5" Y="1229.5" GraphRef="ae2d7" RelX="0.0" RelY="1.0" />
+
       <Point X="1941.5" Y="1229.5" GraphRef="ae2d7" RelX="0.0" RelY="1.0"/>
-
       <Point X="1942.3541666666667" Y="1518.2500000000007" GraphRef="b3d54" RelX="0.5" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1942.3541666666667" Y="1518.2500000000007" GraphRef="b3d54" RelX="0.5" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re56">
   <Interaction GraphId="re56">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="269" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="269" LineThickness="1.0">
-
       <Point X="1297.5" Y="1252.5" GraphRef="sa57" RelX="1.0" RelY="-1.0" />
+
       <Point X="1297.5" Y="1252.5" GraphRef="sa57" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1367.5" Y="1252.5" GraphRef="sa69" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1367.5" Y="1252.5" GraphRef="sa69" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re57">
   <Interaction GraphId="re57">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="270" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="270" LineThickness="1.0">
-
       <Point X="557.5" Y="1152.5" GraphRef="sa61" RelX="-1.0" RelY="0.0" />
+
       <Point X="557.5" Y="1152.5" GraphRef="sa61" RelX="-1.0" RelY="0.0"/>
-
       <Point X="497.5" Y="1152.5" GraphRef="sa72" RelX="1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="497.5" Y="1152.5" GraphRef="sa72" RelX="1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re58">
   <Interaction GraphId="re58">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="271" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="271" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="417.5" Y="1152.5" GraphRef="sa71" RelX="-1.0" RelY="1.0" />
+
       <Point X="417.5" Y="1152.5" GraphRef="sa71" RelX="-1.0" RelY="1.0"/>
-
       <Point X="237.33333333333331" Y="1151.9999999999998" GraphRef="c7b43" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="237.33333333333331" Y="1151.9999999999998" GraphRef="c7b43" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re59">
   <Interaction GraphId="re59">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="272" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="272" LineThickness="1.0">
-
       <Point X="557.5" Y="1202.5" GraphRef="sa62" RelX="-1.0" RelY="0.0" />
+
       <Point X="557.5" Y="1202.5" GraphRef="sa62" RelX="-1.0" RelY="0.0"/>
-
       <Point X="497.5" Y="1232.5" GraphRef="sa74" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="497.5" Y="1232.5" GraphRef="sa74" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re60">
   <Interaction GraphId="re60">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="273" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="273" LineThickness="1.0">
-
       <Point X="417.5" Y="1232.5" GraphRef="sa74" RelX="-1.0" RelY="0.0" />
+
       <Point X="417.5" Y="1232.5" GraphRef="sa74" RelX="-1.0" RelY="0.0"/>
-
       <Point X="367.5" Y="1232.5" GraphRef="sa75" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="367.5" Y="1232.5" GraphRef="sa75" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re61">
   <Interaction GraphId="re61">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="274" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="274" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="287.5" Y="1232.5" GraphRef="sa75" RelX="-1.0" RelY="0.0" />
+
       <Point X="287.5" Y="1232.5" GraphRef="sa75" RelX="-1.0" RelY="0.0"/>
-
       <Point X="241.33333333333337" Y="1232.0000000000005" GraphRef="da94b" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="241.33333333333337" Y="1232.0000000000005" GraphRef="da94b" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re62">
   <Interaction GraphId="re62">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="275" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="275" LineThickness="1.0">
-
       <Point X="557.5" Y="1412.5" GraphRef="sa63" RelX="-1.0" RelY="0.0" />
+
       <Point X="557.5" Y="1412.5" GraphRef="sa63" RelX="-1.0" RelY="0.0"/>
-
       <Point X="497.5" Y="1412.5" GraphRef="sa78" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="497.5" Y="1412.5" GraphRef="sa78" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re63">
   <Interaction GraphId="re63">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="276" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="276" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="417.5" Y="1412.5" GraphRef="sa78" RelX="-1.0" RelY="0.0" />
+
       <Point X="417.5" Y="1412.5" GraphRef="sa78" RelX="-1.0" RelY="0.0"/>
-
       <Point X="252.66666666666654" Y="1411.3333333333337" GraphRef="f3efc" RelX="1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="252.66666666666654" Y="1411.3333333333337" GraphRef="f3efc" RelX="1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re64">
   <Interaction GraphId="re64">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="277" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="277" LineThickness="1.0">
-
       <Point X="997.5" Y="1412.5" GraphRef="sa65" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="1412.5" GraphRef="sa65" RelX="1.0" RelY="0.0"/>
-
       <Point X="1067.5" Y="1412.5" GraphRef="sa80" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="1412.5" GraphRef="sa80" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re65">
   <Interaction GraphId="re65">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="278" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="278" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1147.5" Y="1412.5" GraphRef="sa80" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1412.5" GraphRef="sa80" RelX="1.0" RelY="0.0"/>
-
       <Point X="1888.375" Y="1518.2500000000007" GraphRef="b3d54" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="1888.375" Y="1518.2500000000007" GraphRef="b3d54" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re66">
   <Interaction GraphId="re66">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="279" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="279" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1996.3333333333335" Y="1530.7500000000007" GraphRef="b3d54" RelX="1.0" RelY="0.0" />
+
       <Point X="1996.3333333333335" Y="1530.7500000000007" GraphRef="b3d54" RelX="1.0" RelY="0.0"/>
-
       <Point X="2262.166666666669" Y="1652.8333333333348" GraphRef="a5031" RelX="0.0" RelY="-1.0" ArrowHead="Arrow" />
+
       <Point X="2262.166666666669" Y="1652.8333333333348" GraphRef="a5031" RelX="0.0" RelY="-1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re68">
   <Interaction GraphId="re68">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="281" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="281" LineThickness="1.0">
-
       <Point X="817.5" Y="1572.5" GraphRef="sa86" RelX="1.0" RelY="-1.0" />
+
       <Point X="817.5" Y="1572.5" GraphRef="sa86" RelX="1.0" RelY="-1.0"/>
-
       <Point X="917.5" Y="1572.5" GraphRef="sa84" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="1572.5" GraphRef="sa84" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re69">
   <Interaction GraphId="re69">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="282" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="282" LineThickness="1.0">
-
       <Point X="937.5" Y="1652.5" GraphRef="sa88" RelX="-0.5" RelY="-1.0" />
+
       <Point X="937.5" Y="1652.5" GraphRef="sa88" RelX="-0.5" RelY="-1.0"/>
-
       <Point X="937.5" Y="1615.5" GraphRef="sa84" RelX="-0.5" RelY="1.15" ArrowHead="mim-inhibition" />
+
       <Point X="937.5" Y="1615.5" GraphRef="sa84" RelX="-0.5" RelY="1.15" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re7">
   <Interaction GraphId="re7">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="283" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="283" LineThickness="1.0">
-
       <Point X="1123.75" Y="352.4999999999999" GraphRef="sa7" RelX="1.0" RelY="0.0" />
+
       <Point X="1123.75" Y="352.4999999999999" GraphRef="sa7" RelX="1.0" RelY="0.0"/>
-
       <Point X="1187.5" Y="352.5" GraphRef="sa8" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1187.5" Y="352.5" GraphRef="sa8" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re70">
   <Interaction GraphId="re70">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="284" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="284" LineThickness="1.0">
-
       <Point X="1147.5" Y="1522.5" GraphRef="sa89" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1522.5" GraphRef="sa89" RelX="1.0" RelY="0.0"/>
-
       <Point X="1227.5" Y="1522.5" GraphRef="sa90" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1227.5" Y="1522.5" GraphRef="sa90" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re71">
   <Interaction GraphId="re71">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="285" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="285" LineThickness="1.0">
-
       <Point X="1067.5" Y="1522.5" GraphRef="sa89" RelX="-1.0" RelY="0.0" />
+
       <Point X="1067.5" Y="1522.5" GraphRef="sa89" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="1572.5" GraphRef="sa83" RelX="1.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="1572.5" GraphRef="sa83" RelX="1.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re72">
   <Interaction GraphId="re72">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="286" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="286" LineThickness="1.0">
-
       <Point X="997.5" Y="1572.5" GraphRef="sa84" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="1572.5" GraphRef="sa84" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1070.0" Y="1570.0" GraphRef="sa91" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1070.0" Y="1570.0" GraphRef="sa91" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re73">
   <Interaction GraphId="re73">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="287" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="287" LineThickness="1.0">
-
       <Point X="1150.0" Y="1640.0" GraphRef="sa171" RelX="1.0" RelY="-1.0" />
+
       <Point X="1150.0" Y="1640.0" GraphRef="sa171" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1227.5" Y="1642.5" GraphRef="sa94" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1227.5" Y="1642.5" GraphRef="sa94" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re74">
   <Interaction GraphId="re74">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="288" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="288" LineThickness="1.0">
-
       <Point X="997.5" Y="1572.5" GraphRef="sa84" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="1572.5" GraphRef="sa84" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1070.0" Y="1640.0" GraphRef="sa171" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1070.0" Y="1640.0" GraphRef="sa171" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re75">
   <Interaction GraphId="re75">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="289" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="289" LineThickness="1.0">
-
       <Point X="1147.5" Y="1782.5" GraphRef="sa95" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1782.5" GraphRef="sa95" RelX="1.0" RelY="0.0"/>
-
       <Point X="1227.5" Y="1782.5" GraphRef="sa96" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1227.5" Y="1782.5" GraphRef="sa96" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re76">
   <Interaction GraphId="re76">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="290" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="290" LineThickness="1.0">
-
       <Point X="1147.5" Y="1832.5" GraphRef="sa97" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1832.5" GraphRef="sa97" RelX="1.0" RelY="0.0"/>
-
       <Point X="1224.5" Y="1832.5" GraphRef="sa98" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition" />
+
       <Point X="1224.5" Y="1832.5" GraphRef="sa98" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re77">
   <Interaction GraphId="re77">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="291" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="291" LineThickness="1.0">
-
       <Point X="1307.5" Y="1782.5" GraphRef="sa96" RelX="1.0" RelY="0.0" />
+
       <Point X="1307.5" Y="1782.5" GraphRef="sa96" RelX="1.0" RelY="0.0"/>
-
       <Point X="1387.5" Y="1782.5" GraphRef="sa99" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1387.5" Y="1782.5" GraphRef="sa99" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re78">
   <Interaction GraphId="re78">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="292" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="292" LineThickness="1.0">
-
       <Point X="1467.5" Y="1782.5" GraphRef="sa99" RelX="1.0" RelY="0.0" />
+
       <Point X="1467.5" Y="1782.5" GraphRef="sa99" RelX="1.0" RelY="0.0"/>
-
       <Point X="1534.5" Y="1782.5" GraphRef="sa100" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition" />
+
       <Point X="1534.5" Y="1782.5" GraphRef="sa100" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re79">
   <Interaction GraphId="re79">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="293" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="293" LineThickness="1.0">
-
       <Point X="1307.5" Y="1832.5" GraphRef="sa98" RelX="1.0" RelY="0.0" />
+
       <Point X="1307.5" Y="1832.5" GraphRef="sa98" RelX="1.0" RelY="0.0"/>
-
       <Point X="1384.5" Y="1832.5" GraphRef="sa101" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition" />
+
       <Point X="1384.5" Y="1832.5" GraphRef="sa101" RelX="-1.075" RelY="0.0" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re8">
   <Interaction GraphId="re8">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="294" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="294" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1097.5" Y="482.5" GraphRef="sa11" RelX="0.0" RelY="-1.0" />
+
       <Point X="1097.5" Y="482.5" GraphRef="sa11" RelX="0.0" RelY="-1.0"/>
-
       <Point X="1097.5" Y="373.7499999999999" GraphRef="sa7" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1097.5" Y="373.7499999999999" GraphRef="sa7" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re80">
   <Interaction GraphId="re80">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="295" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="295" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1617.5" Y="1782.5" GraphRef="sa100" RelX="1.0" RelY="0.0" />
+
       <Point X="1617.5" Y="1782.5" GraphRef="sa100" RelX="1.0" RelY="0.0"/>
-
       <Point X="1888.375" Y="1543.2500000000007" GraphRef="b3d54" RelX="0.0" RelY="1.0" ArrowHead="Arrow" />
+
       <Point X="1888.375" Y="1543.2500000000007" GraphRef="b3d54" RelX="0.0" RelY="1.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re81">
   <Interaction GraphId="re81">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="296" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="296" LineThickness="1.0">
-
       <Point X="997.5" Y="1882.5" GraphRef="sa103" RelX="1.0" RelY="1.0" />
+
       <Point X="997.5" Y="1882.5" GraphRef="sa103" RelX="1.0" RelY="1.0"/>
-
       <Point X="1067.5" Y="1782.5" GraphRef="sa95" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="1782.5" GraphRef="sa95" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re82">
   <Interaction GraphId="re82">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="297" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="297" LineThickness="1.0">
-
       <Point X="997.5" Y="1882.5" GraphRef="sa104" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="1882.5" GraphRef="sa104" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1067.5" Y="1832.5" GraphRef="sa97" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1067.5" Y="1832.5" GraphRef="sa97" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re83">
   <Interaction GraphId="re83">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="298" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="298" LineThickness="1.0">
-
       <Point X="1267.5" Y="1852.5" GraphRef="sa98" RelX="0.0" RelY="1.0" />
+
       <Point X="1267.5" Y="1852.5" GraphRef="sa98" RelX="0.0" RelY="1.0"/>
-
       <Point X="1267.6211599041496" Y="1882.4022643440514" />
+
       <Point X="1267.6211599041496" Y="1882.4022643440514"/>
-
       <Point X="997.5" Y="1882.5" GraphRef="sa103" RelX="1.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="1882.5" GraphRef="sa103" RelX="1.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re84">
   <Interaction GraphId="re84">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="299" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="299" LineThickness="1.0">
-
       <Point X="937.5" Y="1952.5" GraphRef="sa105" RelX="-0.5" RelY="-1.0" />
+
       <Point X="937.5" Y="1952.5" GraphRef="sa105" RelX="-0.5" RelY="-1.0"/>
-
       <Point X="937.5" Y="1922.5" GraphRef="sa104" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="937.5" Y="1922.5" GraphRef="sa104" RelX="-0.5" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re85">
   <Interaction GraphId="re85">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="300" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="300" LineThickness="1.0">
-
       <Point X="840.0" Y="1880.0" GraphRef="sa106" RelX="1.0" RelY="0.0" />
+
       <Point X="840.0" Y="1880.0" GraphRef="sa106" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="1882.5" GraphRef="sa103" RelX="-1.0" RelY="1.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="1882.5" GraphRef="sa103" RelX="-1.0" RelY="1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re86">
   <Interaction GraphId="re86">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="301" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="301" LineThickness="1.0">
-
       <Point X="1067.5" Y="1912.5" GraphRef="sa107" RelX="-1.0" RelY="0.0" />
+
       <Point X="1067.5" Y="1912.5" GraphRef="sa107" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="1882.5" GraphRef="sa104" RelX="1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="1882.5" GraphRef="sa104" RelX="1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re87">
   <Interaction GraphId="re87">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="302" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="302" LineThickness="1.0">
-
       <Point X="1067.5" Y="1962.5" GraphRef="sa108" RelX="-1.0" RelY="0.0" />
+
       <Point X="1067.5" Y="1962.5" GraphRef="sa108" RelX="-1.0" RelY="0.0"/>
-
       <Point X="997.5" Y="1902.5" GraphRef="sa104" RelX="1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="997.5" Y="1902.5" GraphRef="sa104" RelX="1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re88">
   <Interaction GraphId="re88">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="303" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="303" LineThickness="1.0">
-
       <Point X="1147.5" Y="1962.5" GraphRef="sa108" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1962.5" GraphRef="sa108" RelX="1.0" RelY="0.0"/>
-
       <Point X="1227.5" Y="1962.5" GraphRef="sa109" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1227.5" Y="1962.5" GraphRef="sa109" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re89">
   <Interaction GraphId="re89">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="304" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="304" LineThickness="1.0">
-
       <Point X="1147.5" Y="1912.5" GraphRef="sa107" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="1912.5" GraphRef="sa107" RelX="1.0" RelY="0.0"/>
-
       <Point X="1387.5" Y="1912.5" GraphRef="sa111" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1387.5" Y="1912.5" GraphRef="sa111" RelX="-1.0" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re9">
   <Interaction GraphId="re9">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="305" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="305" LineThickness="1.0">
-
       <Point X="1097.5" Y="742.5" GraphRef="sa22" RelX="-0.5" RelY="1.0" />
+
       <Point X="1097.5" Y="742.5" GraphRef="sa22" RelX="-0.5" RelY="1.0"/>
-
       <Point X="1097.5" Y="782.5" GraphRef="sa13" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification" />
+
       <Point X="1097.5" Y="782.5" GraphRef="sa13" RelX="-0.5" RelY="-1.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re90">
   <Interaction GraphId="re90">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="306" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="306" LineThickness="1.0">
-
       <Point X="1307.5" Y="1962.5" GraphRef="sa109" RelX="1.0" RelY="0.0" />
+
       <Point X="1307.5" Y="1962.5" GraphRef="sa109" RelX="1.0" RelY="0.0"/>
-
       <Point X="1387.5" Y="1932.5" GraphRef="sa111" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1387.5" Y="1932.5" GraphRef="sa111" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re91">
   <Interaction GraphId="re91">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="307" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="307" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1467.5" Y="1912.5" GraphRef="sa111" RelX="1.0" RelY="-1.0" />
+
       <Point X="1467.5" Y="1912.5" GraphRef="sa111" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1599.6666666666706" Y="1914.0000000000014" GraphRef="b7127" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1599.6666666666706" Y="1914.0000000000014" GraphRef="b7127" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re92">
   <Interaction GraphId="re92">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Elbow" ZOrder="308" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Elbow" ZOrder="308" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="1754.6666666666679" Y="1914.0000000000014" GraphRef="b7127" RelX="1.0" RelY="0.0" />
+
       <Point X="1754.6666666666679" Y="1914.0000000000014" GraphRef="b7127" RelX="1.0" RelY="0.0"/>
-
       <Point X="2101.3333333333335" Y="1789.666666666668" />
+
       <Point X="2101.3333333333335" Y="1789.666666666668"/>
-
       <Point X="2204.3333333333353" Y="1665.3333333333348" GraphRef="a5031" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="2204.3333333333353" Y="1665.3333333333348" GraphRef="a5031" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re93">
   <Interaction GraphId="re93">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="309" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="309" LineThickness="1.0">
-
       <Point X="787.5" Y="2112.5" GraphRef="sa114" RelX="1.0" RelY="0.0" />
+
       <Point X="787.5" Y="2112.5" GraphRef="sa114" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="2112.5" GraphRef="sa113" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2112.5" GraphRef="sa113" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re94">
   <Interaction GraphId="re94">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="310" LineStyle="Broken" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="310" LineStyle="Broken" LineThickness="1.0">
-
       <Point X="997.5" Y="2322.5" GraphRef="sa120" RelX="1.0" RelY="0.0" />
+
       <Point X="997.5" Y="2322.5" GraphRef="sa120" RelX="1.0" RelY="0.0"/>
-
       <Point X="1087.5" Y="2322.5" GraphRef="sa121" RelX="-1.0" RelY="0.0" ArrowHead="Arrow" />
+
       <Point X="1087.5" Y="2322.5" GraphRef="sa121" RelX="-1.0" RelY="0.0" ArrowHead="Arrow"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re95">
   <Interaction GraphId="re95">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="311" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="311" LineThickness="1.0">
-
       <Point X="787.5" Y="2292.5" GraphRef="sa117" RelX="1.0" RelY="0.0" />
+
       <Point X="787.5" Y="2292.5" GraphRef="sa117" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="2262.5" GraphRef="sa119" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2262.5" GraphRef="sa119" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re96">
   <Interaction GraphId="re96">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="312" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="312" LineThickness="1.0">
-
       <Point X="787.5" Y="2292.5" GraphRef="sa117" RelX="1.0" RelY="0.0" />
+
       <Point X="787.5" Y="2292.5" GraphRef="sa117" RelX="1.0" RelY="0.0"/>
-
       <Point X="917.5" Y="2322.5" GraphRef="sa120" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="917.5" Y="2322.5" GraphRef="sa120" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re97">
   <Interaction GraphId="re97">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="313" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="313" LineThickness="1.0">
-
       <Point X="1147.5" Y="2092.5" GraphRef="sa122" RelX="1.0" RelY="0.0" />
+
       <Point X="1147.5" Y="2092.5" GraphRef="sa122" RelX="1.0" RelY="0.0"/>
-
       <Point X="1227.5" Y="2092.5" GraphRef="sa123" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification" />
+
       <Point X="1227.5" Y="2092.5" GraphRef="sa123" RelX="-1.0" RelY="0.0" ArrowHead="mim-modification"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re98">
   <Interaction GraphId="re98">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="314" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="314" LineThickness="1.0">
-
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1064.8952705736267" Y="2093.9884168150707" GraphRef="sa122" RelX="-1.0651182356593325" RelY="0.0744208407535325" ArrowHead="mim-inhibition" />
+
       <Point X="1064.8952705736267" Y="2093.9884168150707" GraphRef="sa122" RelX="-1.0651182356593325" RelY="0.0744208407535325" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Interaction GraphId="re99">
   <Interaction GraphId="re99">
-
     <Comment></Comment>
+
     <Comment/>
     <Graphics ConnectorType="Segmented" ZOrder="315" LineThickness="1.0">
     <Graphics ConnectorType="Segmented" ZOrder="315" LineThickness="1.0">
-
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0" />
+
       <Point X="997.5" Y="2132.5" GraphRef="sa118" RelX="1.0" RelY="-1.0"/>
-
       <Point X="1064.5301515190165" Y="2142.075735931288" GraphRef="sa125" RelX="-1.0742462120245875" RelY="-0.021213203435604556" ArrowHead="mim-inhibition" />
+
       <Point X="1064.5301515190165" Y="2142.075735931288" GraphRef="sa125" RelX="-1.0742462120245875" RelY="-0.021213203435604556" ArrowHead="mim-inhibition"/>
     </Graphics>
     </Graphics>
-
     <Xref Database="" ID="" />
+
     <Xref Database="" ID=""/>
   </Interaction>
   </Interaction>
   <Label TextLabel="Axon outgrowth" GraphId="a11b7">
   <Label TextLabel="Axon outgrowth" GraphId="a11b7">
-
     <Graphics CenterX="2360.166666666664" CenterY="302.66666666666674" Width="119.66666666666706" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="2360.166666666664" CenterY="302.66666666666674" Width="119.66666666666706" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Axon repulsion" GraphId="a5031">
   <Label TextLabel="Axon repulsion" GraphId="a5031">
-
     <Graphics CenterX="2262.166666666669" CenterY="1665.3333333333348" Width="115.66666666666694" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="2262.166666666669" CenterY="1665.3333333333348" Width="115.66666666666694" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Transcription" GraphId="a88fa">
   <Label TextLabel="Transcription" GraphId="a88fa">
-
     <Graphics CenterX="1512.0000000000011" CenterY="302.6666666666669" Width="90.0" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1512.0000000000011" CenterY="302.6666666666669" Width="90.0" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Attraction" GraphId="c7b43">
   <Label TextLabel="Attraction" GraphId="c7b43">
-
     <Graphics CenterX="189.49999999999994" CenterY="1151.9999999999998" Width="95.66666666666674" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="189.49999999999994" CenterY="1151.9999999999998" Width="95.66666666666674" Height="25.0" ZOrder="28672" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Repulsion" GraphId="da94b">
   <Label TextLabel="Repulsion" GraphId="da94b">
-
     <Graphics CenterX="193.5" CenterY="1232.0000000000005" Width="95.66666666666674" Height="25.0" ZOrder="32770" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="193.5" CenterY="1232.0000000000005" Width="95.66666666666674" Height="25.0" ZOrder="32770" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Attraction" GraphId="f3efc">
   <Label TextLabel="Attraction" GraphId="f3efc">
-
     <Graphics CenterX="204.83333333333317" CenterY="1411.3333333333337" Width="95.66666666666674" Height="25.0" ZOrder="32771" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="204.83333333333317" CenterY="1411.3333333333337" Width="95.66666666666674" Height="25.0" ZOrder="32771" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Axon attraction" GraphId="f3965">
   <Label TextLabel="Axon attraction" GraphId="f3965">
-
     <Graphics CenterX="2473.5000000000055" CenterY="2094.0000000000005" Width="115.66666666666694" Height="25.0" ZOrder="32772" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="2473.5000000000055" CenterY="2094.0000000000005" Width="115.66666666666694" Height="25.0" ZOrder="32772" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Label TextLabel="Microtubule organization" GraphId="b7127">
   <Label TextLabel="Microtubule organization" GraphId="b7127">
-
     <Graphics CenterX="1677.1666666666692" CenterY="1914.0000000000014" Width="154.99999999999721" Height="25.0" ZOrder="32773" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle" />
+
     <Graphics CenterX="1677.1666666666692" CenterY="1914.0000000000014" Width="154.99999999999721" Height="25.0" ZOrder="32773" FillColor="ffffff" FontWeight="Bold" FontSize="12" Valign="Middle"/>
   </Label>
   </Label>
   <Shape TextLabel="Neuron" GraphId="ca1">
   <Shape TextLabel="Neuron" GraphId="ca1">
-
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" />
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/>
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="1780.0" CenterY="1730.0" Width="1625.0" Height="3205.0" ZOrder="1" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0" />
+
     <Graphics CenterX="1780.0" CenterY="1730.0" Width="1625.0" Height="3205.0" ZOrder="1" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape TextLabel="Guidance cues" GraphId="ca2">
   <Shape TextLabel="Guidance cues" GraphId="ca2">
-
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" />
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/>
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="362.5" CenterY="1297.5" Width="470.0" Height="530.0" ZOrder="2" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0" />
+
     <Graphics CenterX="362.5" CenterY="1297.5" Width="470.0" Height="530.0" ZOrder="2" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0"/>
   </Shape>
   </Shape>
   <Shape TextLabel="Null" GraphId="ca3">
   <Shape TextLabel="Null" GraphId="ca3">
-
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell" />
+
     <Attribute Key="org.pathvisio.CellularComponentProperty" Value="Cell"/>
-
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double" />
+
     <Attribute Key="org.pathvisio.DoubleLineProperty" Value="Double"/>
-
     <Graphics CenterX="647.5" CenterY="2162.5" Width="225.0" Height="185.0" ZOrder="3" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0" />
+
     <Graphics CenterX="647.5" CenterY="2162.5" Width="225.0" Height="185.0" ZOrder="3" FontSize="12" Valign="Bottom" ShapeType="Rectangle" LineThickness="3.0" Rotation="0.0"/>
   </Shape>
   </Shape>
-
   <Group GroupId="d677a" GraphId="bbfa1" Style="Group" />
+
   <Group GroupId="d677a" GraphId="bbfa1" Style="Group"/>
-
   <InfoBox CenterX="0.0" CenterY="0.0" />
+
   <InfoBox CenterX="0.0" CenterY="0.0"/>
   <Biopax>
   <Biopax>
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
     <bp:openControlledVocabulary xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#">
Line 2,049: Line 2,049:
     </bp:PublicationXref>
     </bp:PublicationXref>
     <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="ba3">
     <bp:PublicationXref xmlns:bp="http://www.biopax.org/release/biopax-level3.owl#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" rdf:id="ba3">
-
       <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:ID>
+
       <bp:ID rdf:datatype="http://www.w3.org/2001/XMLSchema#string"/>
       <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
       <bp:DB rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubMed</bp:DB>
-
       <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:TITLE>
+
       <bp:TITLE rdf:datatype="http://www.w3.org/2001/XMLSchema#string"/>
       <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://www.kegg.jp/entry/map04360</bp:SOURCE>
       <bp:SOURCE rdf:datatype="http://www.w3.org/2001/XMLSchema#string">https://www.kegg.jp/entry/map04360</bp:SOURCE>
-
       <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string"></bp:YEAR>
+
       <bp:YEAR rdf:datatype="http://www.w3.org/2001/XMLSchema#string"/>
     </bp:PublicationXref>
     </bp:PublicationXref>
   </Biopax>
   </Biopax>
</Pathway>
</Pathway>

Current revision

Error rendering pathway page

This revision of the pathway probably contains invalid GPML code. If this happens to the most recent revision, try reverting the pathway using the pathway history displayed below or contact the site administrators (see WikiPathways:About) to resolve this problem.

Pathway history

View all...
CompareRevisionActionTimeUserComment
129446view15:59, 20 April 2024EweitzModified title
129395view17:39, 8 April 2024Khanspersadded KEGG pathway as reference
129394view17:38, 8 April 2024KhanspersOntology Term : 'signaling pathway pertinent to the brain and nervous system' added !
129393view17:37, 8 April 2024KhanspersOntology Term : 'neuron' added !
129392view17:34, 8 April 2024Khanspersadded xrefs, updated interactions, removed redundant and empty nodes
129389view00:36, 6 April 2024Khanspersupdated interactions to elbows, changed pathway nodes to labels
129388view00:21, 6 April 2024Khanspersremoved fill color for nodes and cell shapes, updated pathway and metabolite nodes
124308view16:09, 12 October 2022LLadeiraModified title
124307view16:06, 12 October 2022LLadeiraNew pathway

Error details

exception 'Exception' with message 'Unable to convert to /var/www/wikipathways/images/2/2e/WP5289_prev.svg:
<BR>Status:1
<BR>Message:Exception in thread "main" java.lang.NullPointerException
	at org.pathvisio.core.Engine.getPathwayImporters(Unknown Source)
	at org.pathvisio.core.Engine.importPathway(Unknown Source)
	at org.pathvisio.core.util.Converter.main(Unknown Source)

<BR>Command:java -Xmx1024M -jar /var/www/wikipathways/wpi/bin/pathvisio_core.jar "/var/www/wikipathways" "/var/www/wikipathways/images/2/2e/WP5289_prev.svg" 2>&1<BR>' in /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php:1255
Stack trace:
#0 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1227): Pathway::convertWithPathVisio(false, '/var/www/wikipa...')
#1 /var/www/wikipathways/wpi/extensions/Pathways/Pathway.php(1137): Pathway->saveConvertedByPathVisioCache('svg')
#2 /var/www/wikipathways/wpi/extensions/Pathways/PathwayPage.php(21): Pathway->updateCache('svg')
#3 [internal function]: renderPathwayPage(Object(Parser), '<?xml version="...', Object(StripState))
#4 /var/www/wikipathways/includes/Hooks.php(125): call_user_func_array('renderPathwayPa...', Array)
#5 /var/www/wikipathways/includes/parser/Parser.php(318): wfRunHooks('ParserBeforeStr...', Array)
#6 /var/www/wikipathways/includes/OutputPage.php(405): Parser->parse('<?xml version="...', Object(Title), Object(ParserOptions), true, true, 129446)
#7 /var/www/wikipathways/includes/OutputPage.php(391): OutputPage->addWikiTextTitle('<?xml version="...', Object(Title), true, true)
#8 /var/www/wikipathways/includes/OutputPage.php(500): OutputPage->addWikiTextTitleTidy('<?xml version="...', Object(Title), true)
#9 /var/www/wikipathways/includes/DifferenceEngine.php(313): OutputPage->addWikiTextTidy('<?xml version="...')
#10 /var/www/wikipathways/includes/DifferenceEngine.php(271): DifferenceEngine->renderNewRevision()
#11 /var/www/wikipathways/includes/Article.php(729): DifferenceEngine->showDiffPage(false)
#12 /var/www/wikipathways/includes/Wiki.php(437): Article->view()
#13 /var/www/wikipathways/includes/Wiki.php(59): MediaWiki->performAction(Object(OutputPage), Object(Article), Object(Title), Object(User), Object(WebRequest))
#14 /var/www/wikipathways/index.php(93): MediaWiki->initialize(Object(Title), Object(Article), Object(OutputPage), Object(User), Object(WebRequest))
#15 {main}
Personal tools