Lipid particles composition (Homo sapiens)

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ArcPathVisio Brace Ellipse EndoplasmicReticulum GolgiApparatus HexagonPathVisio MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TriangleEquilateralEast TrianglePathVisio none aka LDL1ROSHDLLDLRIDLLDLLPLFAglycerolcholesterylesterApo C-IIIApo C-IIcholesterolCETPApo A-IIApo ELCATApo A-ITGApo B-100cholesterylesterApo EApo C-IIApo C-IIIVLDLApo B-48Apo EApo C-IIApo C-IIITGcholesterolChylomicroncholesterolcholesteroloxLDLcholesterolaka LDL2Apo EName: Lipid particles compositionOrganism: Homo sapiens


Description

This particle describes the chemical composition of various lipid particles. See also [WP430](https://www.wikipathways.org/index.php/Pathway:WP430) for a basic overview of cholesterol synthesis, and for the disease related to the lipoproteins in this pathway see [WP4522](https://www.wikipathways.org/index.php/Pathway:WP4522).

Additional sources

[A. Goldberg, Overview of Lipid Metabolism, 2015.](http://www.msdmanuals.com/professional/endocrine-and-metabolic-disorders/lipid-disorders/overview-of-lipid-metabolism).

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Quality Tags

Image:Curated.pngApproved version
Image:MissingXref.pngAnnotate nodes

Ontology Terms

Pathway Ontology : prolactin signaling pathway
 

Bibliography

  1. Steinberg D; ''Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis.''; Circulation, 1997 PubMed Europe PMC Scholia
  2. Mahley RW; ''Apolipoprotein E: cholesterol transport protein with expanding role in cell biology.''; Science, 1988 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
137976
Approved
view21:13, 10 March 2025KhanspersModified description
117687view12:09, 22 May 2021EweitzModified title
106212view12:10, 16 August 2019MaintBotHMDB identifier normalization
103449view16:42, 1 March 2019DeSlModified description
89202view04:01, 23 August 2016AriuttaOntology Term : 'lipid metabolic pathway' added !
87388view11:05, 22 July 2016MaintBotadded missing graphids
84331view09:02, 6 February 2016EgonwMarked complex labels with ChEBI IDs as metabolite.
84144view13:49, 19 January 2016EgonwAnother piece of the puzzle (HT to Freddy for pointing me to the paper)
84085view12:24, 13 January 2016EgonwAdded a reference for the LDL->oxLDL conversion.
84017view16:10, 10 January 2016EgonwMore info and more particles.
84004view15:14, 9 January 2016EgonwAdded TG to VLDL.
84003view15:08, 9 January 2016EgonwAdded more identifiers.
84002view14:55, 9 January 2016EgonwModified description
84001view14:54, 9 January 2016EgonwModified description
84000view14:51, 9 January 2016EgonwModified title
83999view14:50, 9 January 2016EgonwNew pathway

External references

DataNodes

View all...
Name  ↓Type  ↓Database reference  ↓Comment  ↓
Apo A-IIProteinP02652 (Uniprot-TrEMBL)
Apo A-IProteinP02647 (Uniprot-TrEMBL)
Apo B-100ProteinP04114 (Uniprot-TrEMBL)
Apo B-48Protein
Apo C-IIIProteinP02656 (Uniprot-TrEMBL)
Apo C-IIProteinP02655 (Uniprot-TrEMBL)
Apo EProteinP02649 (Uniprot-TrEMBL)
CETPGeneProductENSG00000087237 (Ensembl)
ChylomicronComplex
FAMetaboliteCHEBI:35366 (ChEBI)
HDLMetaboliteCHEBI:39025 (ChEBI)
IDLComplex
LCATGeneProductENSG00000213398 (Ensembl)
LDLMetaboliteCHEBI:39026 (ChEBI)
LDLRGeneProductENSG00000130164 (Ensembl)
LPLGeneProductENSG00000175445 (Ensembl)
ROSMetaboliteCHEBI:26523 (ChEBI)
TGMetaboliteCHEBI:17855 (ChEBI)
VLDLMetaboliteCHEBI:39027 (ChEBI)
cholesterolMetaboliteHMDB0000067 (HMDB)
cholesteryl esterMetaboliteCHEBI:17002 (ChEBI)
glycerolMetaboliteHMDB0000131 (HMDB)
oxLDLMetaboliteCHEBI:60151 (ChEBI)

Annotated Interactions

No annotated interactions

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