Metabolism overview (Homo sapiens)

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Transaminationsβ-OxidationFatty acid biosynthesisKetone bodies metabolismPentose Phosphates PathwayUrea cycleAcyl glycerol metabolismGlycolysisGluconeogenesisCitric acid cycleGlycogen metabolismErythrose4-phosphateArgininosuccinicCitrullineOxaoacetic acid2-trans-hexadecenoyl-CoAGlycogen6-Phospho-gluconelactoneGlyceraldehyde-3-phosphateGlutamic acidPhosphatidic acidGlyceraldehyde-3-phosphateMalonyl-CoAOctanoyl-ACP2-OxoglutaricAcetoacetyl-CoAFatty acyl CoAPalmitoyl-ACPGlutamic acidPhosphoenolpyruvaatRibulose5-phosphateα-Amino acidDiacylglycerolGlyceraldehyde3-phosphateglycerol-3-phosphatePyruvic acidNH3Oxaloacetic acid3-Hydroxy-hexadecanoyl-ACPAcetyl Coenzyme A2-oxo acidGlycerolPyruvic acidMalic acidPalmitoyl-CoARibose-5-phosphate6-phosphonicacid3-hydroxy-CoA hexadecanoylArginineSedoheptulose7-phosphateAspartic acidAlanineDihydroxy acetonephosphate1,3-BiphosphoglycericTriacylglycerolTAGAspartic acidFructase-6-phosphateMalonyl ACPCarbonyl phosphateFructose-1,6-biphosphateMalic acid3-oxo-palmitoyl-CoAGlucose-6-phosphatase2-PhosphoglycerateXylulose5-phosphate2-trans-hexadecenoyl-ACPMonoacylglycerolMAGOxaloacetic acidPalmitoyl carnitineFatty acidUrea3-Oxo-hexadecanoyl-ACPUDP-glucoseAcetyl Coenzyme AGlucoseCitric acidCitric acidSuccinic AcidLysophosphatic acidOxaloacetic acid3-phosphoglycerateAcetyl-ACPGlutamine Palmitic acidFructose-2,6-biphosphate2-Oxo acidGlucose-1-phosphateDiacylglycerolPyruvic acidAspartic acidα-amino acidMalic acidglycerol-3-phosphateDihydroxy acetonephosphateFructase-6-phosphateTetradecanoyl-ACP2-trans-tetradecanoyl-ACP3-hydroxy-tetradecanoyl-ACP3-oxo-tetradecanoyl-ACPDodecanoyl-ACP2-trans-dodecanoyl-ACP3-hydroxy-dodecanoyl-ACP3-oxo-dodecanoyl-ACPDecanoyl-ACP2-trans-decanoyl-ACP3-hydroxy-decanoyl-ACP3-oxo-decanoyl-ACP2-trans-octenoyl-ACP3-Hydroxy-octenoyl-ACP3-oxo-octanoyl-ACPHexanoyl-ACP2-trans-hexanoyl-ACP3-Hydroxy hexanoyl-ACP3-oxo-hexanoyl-ACPButyryl-ACP2-trans-butenoyl-ACP2-hydroxy-butyryl-ACPAcetoacetyl-ACPPyruvic acidPalmitoyl carnitinePalmitoyl-CoATetradecanoyl-CoA2-trans-tetradecanoyl-CoA3-hydroxy-tetradecanoyl-CoA3-oxo-tetradecanoyl-CoADodecanoyl-CoA2-trans-dodecanoyl-CoA3-hydroxy-dodecanoyl-CoA3-oxo-dodecanoyl-CoADecanoyl-CoA2-trans-decanoyl-CoA3-hydroxy-decanoyl-CoA3-oxo-decanoyl-CoAOctanoyl-CoA2-trans-octenoyl-CoA3-Hydroxy-octenoyl-CoA3-oxo-octanoyl-CoAHexanoyl-CA2-trans-hexanoyl-CoA3-Hydroxy hexanoyl-CoA3-oxo-hexanoyl-CoAButyryl-CoA2-trans-butenoyl-CoA2-hydroxy-butyryl-CoAAcetoacetyl-CoAPyruvic acidAcetoacetic AcidSuccinyl-CoAAcetoacetyl-CoAHMG-CoAAcetoacetic acidAcetone3-hydroxybutyric acidKetone bodies metabolismIsocitric acid2-Oxoglutaric acidSuccinyl-CoASuccinic acidFumaric acidMalic acidOxaloacetic acidGlyoxylic acidOxaloacetic acidα-Amino acid2-Oxo acidα-Amino acidα-Amino acid2-Oxo acid2-Oxo acidα-Amino acid2-Oxo acidAspartic acid2-Oxo acidα-Amino acid2-Oxoglutaric acidFumaric acidOrnithine


Description

High level overview of human metabolism, including fatty acid biosynthesis, beta-oxidation, ketone metabolism, citric acid cycle, urea cycle, transamination, and glycogen metabolism.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
124180view07:19, 25 September 2022Egonwsmall typo fix
124179view07:14, 25 September 2022EgonwFixed a KEGG identifier
124178view06:24, 25 September 2022EgonwAdded the missing protein part of the name
123798view12:14, 15 August 2022Egonwsmall typo fix
116568view10:51, 8 May 2021EweitzModified title
116567view10:50, 8 May 2021EweitzModified description
107971view10:55, 18 November 2019FehrhartConnected unconnected lines
107895view13:32, 9 November 2019EgonwFixed char encoding issues and some spelling errors.
107892view13:09, 9 November 2019EgonwModified description
102898view12:27, 27 January 2019EgonwFixed the identifier for palmitic acid.
94732view14:55, 5 October 2017DeSlConnected unconnected lines.
94722view14:14, 5 October 2017DeSlConnected unconnected lines
88646view15:02, 12 August 2016JmeliusOntology Term : 'classic metabolic pathway' added !
85642view16:54, 4 June 2016EgonwFixed an incomplete ID.
84021view08:41, 11 January 2016CLemmensModified description
84020view08:39, 11 January 2016CLemmensNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,3-BiphosphoglycericMetaboliteC00236 (KEGG Compound)
2-Oxo acidMetaboliteC00161 (KEGG Compound)
2-Oxoglutaric acidMetaboliteC00026 (KEGG Compound)
2-OxoglutaricMetaboliteC00026 (KEGG Compound)
2-PhosphoglycerateMetaboliteC00631 (KEGG Compound)
2-hydroxy-butyryl-ACPMetaboliteC04618 (KEGG Compound)
2-hydroxy-butyryl-CoAMetaboliteC01144 (KEGG Compound)
2-oxo acidMetaboliteC00611 (KEGG Compound)
2-trans-butenoyl-ACPMetaboliteC04618 (KEGG Compound)
2-trans-butenoyl-CoAMetaboliteC00877 (KEGG Compound)
2-trans-decanoyl-ACPMetaboliteC05754 (KEGG Compound)
2-trans-decanoyl-CoAMetaboliteC05275 (KEGG Compound)
2-trans-dodecanoyl-ACPMetaboliteC05758 (KEGG Compound)
2-trans-dodecanoyl-CoAMetaboliteC03221 (KEGG Compound)
2-trans-hexadecenoyl-ACPMetaboliteC05763 (KEGG Compound)
2-trans-hexadecenoyl-CoAMetaboliteC05272 (KEGG Compound)
2-trans-hexanoyl-ACPMetaboliteC05748 (KEGG Compound)
2-trans-hexanoyl-CoAMetaboliteC05271 (KEGG Compound)
2-trans-octenoyl-ACPMetaboliteC05751 (KEGG Compound)
2-trans-octenoyl-CoAMetaboliteC05276 (KEGG Compound)
2-trans-tetradecanoyl-ACPMetaboliteC05761 (KEGG Compound)
2-trans-tetradecanoyl-CoAMetaboliteC05273 (KEGG Compound)
3-Hydroxy hexanoyl-ACPMetaboliteC05747 (KEGG Compound)
3-Hydroxy hexanoyl-CoAMetaboliteC05268 (KEGG Compound)
3-Hydroxy-hexadecanoyl-ACPMetaboliteC04633 (KEGG Compound)
3-Hydroxy-octenoyl-ACPMetaboliteC04620 (KEGG Compound)
3-Hydroxy-octenoyl-CoAMetaboliteC05266 (KEGG Compound)
3-Oxo-hexadecanoyl-ACPMetaboliteC05762 (KEGG Compound)
3-hydroxy-CoA hexadecanoylMetaboliteC05258 (KEGG Compound)
3-hydroxy-decanoyl-ACP MetaboliteC04619 (KEGG Compound)
3-hydroxy-decanoyl-CoA MetaboliteC05264 (KEGG Compound)
3-hydroxy-dodecanoyl-ACPMetaboliteC05757 (KEGG Compound)
3-hydroxy-dodecanoyl-CoAMetaboliteC05262 (KEGG Compound)
3-hydroxy-tetradecanoyl-ACPMetaboliteC04688 (KEGG Compound)
3-hydroxy-tetradecanoyl-CoAMetaboliteC05260 (KEGG Compound)
3-hydroxybutyric acidMetaboliteC01089 (KEGG Compound)
3-oxo-decanoyl-ACPMetaboliteC05753 (KEGG Compound)
3-oxo-decanoyl-CoAMetaboliteC05265 (KEGG Compound)
3-oxo-dodecanoyl-ACPMetaboliteC05756 (KEGG Compound)
3-oxo-dodecanoyl-CoAMetaboliteC05261 (KEGG Compound)
3-oxo-hexanoyl-ACPMetaboliteC05746 (KEGG Compound)
3-oxo-hexanoyl-CoAMetaboliteC05269 (KEGG Compound)
3-oxo-octanoyl-ACPMetaboliteC05750 (KEGG Compound)
3-oxo-octanoyl-CoAMetaboliteC05267 (KEGG Compound)
3-oxo-palmitoyl-CoAMetaboliteC05259 (KEGG Compound)
3-oxo-tetradecanoyl-ACPMetaboliteC05759 (KEGG Compound)
3-oxo-tetradecanoyl-CoAMetaboliteC05261 (KEGG Compound)
3-phosphoglycerateMetaboliteC00197 (KEGG Compound)
6-Phospho-glucone lactoneMetabolite439452 (PubChem-compound)
6-phosphonic acidMetabolite91493 (PubChem-compound)
Acetoacetic AcidMetaboliteC00164 (KEGG Compound)
Acetoacetic acidMetaboliteC00164 (KEGG Compound)
Acetoacetyl-ACPMetaboliteC05744 (KEGG Compound)
Acetoacetyl-CoAMetaboliteC00332 (KEGG Compound)
AcetoneMetaboliteC00207 (KEGG Compound)
Acetyl Coenzyme AMetaboliteC00024 (KEGG Compound)
Acetyl-ACPMetaboliteC03939 (KEGG Compound)
AlanineMetaboliteC00133 (KEGG Compound)
ArginineMetaboliteC00062 (KEGG Compound)
ArgininosuccinicMetaboliteCHEBI:15682 (ChEBI)
Aspartic acidMetaboliteC00036 (KEGG Compound)
Aspartic acidMetaboliteC00049 (KEGG Compound)
Butyryl-ACPMetaboliteC05745 (KEGG Compound)
Butyryl-CoAMetaboliteC00136 (KEGG Compound)
Carbonyl phosphateMetaboliteC00169 (KEGG Compound)
Citric acidMetaboliteC00158 (KEGG Compound)
CitrullineMetaboliteC00327 (KEGG Compound)
Decanoyl-ACPMetaboliteC05755 (KEGG Compound)
Decanoyl-CoAMetaboliteC05274 (KEGG Compound)
DiacylglycerolMetaboliteC00641 (KEGG Compound)
Dihydroxy acetone phosphateMetaboliteC00111 (KEGG Compound)
Dodecanoyl-ACPMetaboliteC05223 (KEGG Compound)
Dodecanoyl-CoAMetaboliteC01832 (KEGG Compound)
Erythrose 4-phosphateMetaboliteC05382 (KEGG Compound)
Fatty acidMetaboliteC00162 (KEGG Compound)
Fatty acyl CoAMetaboliteC00040 (KEGG Compound)
Fructase-6 -phosphateMetaboliteC00085 (KEGG Compound)
Fructase-6-phosphateMetaboliteC00085 (KEGG Compound)
Fructose-1,6-biphosphateMetaboliteC05345 (KEGG Compound)
Fructose-2,6-biphosphateMetabolite105021 (PubChem-compound)
Fumaric acidMetaboliteC00122 (KEGG Compound)
Glucose-1- phosphateMetaboliteC00103 (KEGG Compound)
Glucose-6-phosphataseMetaboliteC00668 (KEGG Compound)
GlucoseMetaboliteC00031 (KEGG Compound)
Glutamic acidMetaboliteC00025 (KEGG Compound)
Glutamine MetaboliteC00064 (KEGG Compound)
Glyceraldehyde 3-phosphateMetaboliteC05345 (KEGG Compound)
Glyceraldehyde-3- phosphateMetaboliteC00118 (KEGG Compound)
GlycerolMetaboliteC00116 (KEGG Compound)
GlycogenMetaboliteC00182 (KEGG Compound)
Glyoxylic acidMetaboliteC00048 (KEGG Compound)
HMG-CoAMetaboliteC00356 (KEGG Compound)
Hexanoyl-ACPMetaboliteC05749 (KEGG Compound)
Hexanoyl-CAMetaboliteC05270 (KEGG Compound)
Isocitric acidMetaboliteC00311 (KEGG Compound)
Lysophosphatic acidMetaboliteC00681 (KEGG Compound)
Malic acidMetaboliteC00122 (KEGG Compound)
Malic acidMetaboliteC00149 (KEGG Compound)
Malonyl ACPMetaboliteC01209 (KEGG Compound)
Malonyl-CoAMetaboliteC00083 (KEGG Compound)
Monoacylglycerol MAGMetaboliteC01885 (KEGG Compound)
NH3MetaboliteC00014 (KEGG Compound)
Octanoyl-ACPMetaboliteC05752 (KEGG Compound)
Octanoyl-CoAMetaboliteC01944 (KEGG Compound)
OrnithineMetaboliteC00077 (KEGG Compound)
Oxaloacetic acidMetaboliteC00036 (KEGG Compound)
Oxaloacetic acidMetaboliteC00122 (KEGG Compound)
Oxaoacetic acidMetaboliteC00036 (KEGG Compound)
Palmitic acidMetaboliteQ209727 (Wikidata)
Palmitoyl carnitineMetaboliteC02990 (KEGG Compound)
Palmitoyl-ACPMetaboliteC05764 (KEGG Compound)
Palmitoyl-CoAMetaboliteC00154 (KEGG Compound)
Phosphatidic acidMetaboliteC00416 (KEGG Compound)
PhosphoenolpyruvaatMetaboliteC00074 (KEGG Compound)
Pyruvic acidMetaboliteC00022 (KEGG Compound)
Ribose-

5-phosphate

MetaboliteC00117 (KEGG Compound)
Ribulose 5-phosphateMetaboliteC00199 (KEGG Compound)
Sedoheptulose 7-phosphateMetaboliteC05382 (KEGG Compound)
Succinic AcidMetaboliteC00042 (KEGG Compound)
Succinic acidMetaboliteC00042 (KEGG Compound)
Succinyl-CoAMetaboliteC00091 (KEGG Compound)
Tetradecanoyl-ACPMetaboliteC05761 (KEGG Compound)
Tetradecanoyl-CoAMetaboliteC02593 (KEGG Compound)
Triacylglycerol TAGMetaboliteC00422 (KEGG Compound)
UDP-glucoseMetaboliteC00029 (KEGG Compound)
UreaMetaboliteC00086 (KEGG Compound)
Xylulose 5-phosphateMetaboliteC00231 (KEGG Compound)
glycerol-3- phosphateMetaboliteC00093 (KEGG Compound)
α-Amino acidMetaboliteC00151 (KEGG Compound)
α-amino acidMetaboliteC00151 (KEGG Compound)

Annotated Interactions

No annotated interactions

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