Methionine degradation (Saccharomyces cerevisiae)
From WikiPathways
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize.
Description from [KEGG](https://www.kegg.jp/entry/map00270).
Quality Tags
Ontology Terms
Bibliography
- ''Cysteine and methionine metabolism''; KEGG,
- ''YeastPathways''; YeastPathways,
History
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External references
DataNodes
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Name ![]() | Type ![]() | Database reference ![]() | Comment ![]() |
---|---|---|---|
ATP | Metabolite | 1927-31-7 (CAS) ![]() | |
H+ | Metabolite | 15378 (ChEBI) ![]() | |
H2O | Metabolite | 15377 (ChEBI) ![]() | |
L-methionine | Metabolite | 63-68-3 (CAS) ![]() | |
S-adenosyl-L-homocysteine | Metabolite | 57856 (ChEBI) ![]() | |
S-adenosyl-L-methionine | Metabolite | 59789 (ChEBI) ![]() | |
SAH1 | GeneProduct | S000000845 (SGD) ![]() | |
SAM1 | GeneProduct | S000004170 (SGD) ![]() | |
SAM2 | GeneProduct | S000002910 (SGD) ![]() | |
adenosine | Metabolite | 58-61-7 (CAS) ![]() | |
diphosphate | Metabolite | 2466-09-3 (CAS) ![]() | |
homocysteine | Metabolite | 6027-13-0 (CAS) ![]() | |
phosphate | Metabolite | 14265-44-2 (CAS) ![]() |
Annotated Interactions
No annotated interactions