This pathway is inspired by the Lipidmaps>Sphingolipids pathway [1].
Sphingolipids are a class of lipids, which act as signal transduction and cell recognition molecules.
This pathway provides an overview of the different tail lengths (on the right), which are used to convert sphinganine to DH-ceramide. All products are annotated with a lipid-class identifier.
Han G, Gupta SD, Gable K, Niranjanakumari S, Moitra P, Eichler F, Brown RH Jr, Harmon JM, Dunn TM; ''Identification of small subunits of mammalian serinepalmitoyltransferase that confer distinct acyl-CoA substrate specificities.''; Proc Natl Acad Sci U S A, 2009 PubMedEurope PMCScholia
Merrill AH Jr; ''De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway.''; J Biol Chem, 2002 PubMedEurope PMCScholia
Dennis EA, Deems RA, Harkewicz R, Quehenberger O, Brown HA, Milne SB, Myers DS, Glass CK, Hardiman G, Reichart D, Merrill AH Jr, Sullards MC, Wang E, Murphy RC, Raetz CR, Garrett TA, Guan Z, Ryan AC, Russell DW, McDonald JG, Thompson BM, Shaw WA, Sud M, Zhao Y, Gupta S, Maurya MR, Fahy E, Subramaniam S; ''''; , PubMedEurope PMCScholia
Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
Ontology Terms
Bibliography
History
External references
DataNodes
Annotated Interactions